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The map label for this gene is aprA [H]

Identifier: 77459585

GI number: 77459585

Start: 3839091

End: 3840497

Strand: Reverse

Name: aprA [H]

Synonym: Pfl01_3363

Alternate gene names: 77459585

Gene position: 3840497-3839091 (Counterclockwise)

Preceding gene: 77459588

Following gene: 77459583

Centisome position: 59.65

GC content: 62.33

Gene sequence:

>1407_bases
ATGTCTCAACCTTCCTCCCAGGCCAGCAGCGCCTACACCGCCGTCGACACCTTCAGTCACCTGTACGACCGGGGCACCGG
CACCGTCAATGGCAAACCGTCGTTCACCGCCGACCAGGCCGCTGACGAAATCCTGCGCAAGGGCATGTCGTGGCAGGACA
AGAATGCCGACGGCAAGATTGATCTGACCTACACGTTCCTGACCGACAAACCGTCGAACTACAACGCGAAACTCGGCAAC
TTCAGCGAGTTCAGCGCCCAGCAAAAAGCCCAGGCCGTGCTGTCGATGCAATCGTGGTCGGACGTGGCCAAAGTCACCTT
CACCGAAGGCAAGGGCGGCGACGGTCACATGACCTTCGGCAACTACGACGTCAGCACCGGCGGCGCAGCGTTCGCCTACC
TGCCGCAGGGCAGCAGCTACGACGGTCAATCGTGGTACCTGATCAACGATCAGTACCAGGTCAACAAGACCCCGGACGCC
AACAACTACGGGCGTCAGACCCTGACCCACGAAATCGGCCACACCCTCGGCCTGTCGCACCCGGGCGCCTACAACGCCGG
CAACGGCAACCCGACCTACGGCGACGCCAAATACGCCGAAGACACCCGTGGCTACAGCCTGATGAGCTACTGGAGCGAAG
CCAACACCGACCAGAACTTCAGCAAGGACGGCAGCGGCGCCTACGCCTCGGCACCGTTGATGGACGACATCGTCGCGGTG
CAGAAACTCTACGGCGCCAACTTCGAAACCCGTGCCGACAACACCGTGTACGGCTTCAACTCGAACGCCGATCGCGACTT
CTACAGCGCCACGTCGAACACCTCGAAAGTGGTGTTCTCGGTGTGGGACGGCGGCGGCAATGACACCCTGGATTTCTCCG
GCTTCAACCAAAACCAGAAGATCAACCTCAACGAAGGCTCGTTCTCCGATGTCGGCGGTCTGGTGGGCAACGTGTCCATC
GCCCACGGTGTGACCGTGGAAAATGCCATTGGCGGTTCGGGCAGTGACCTGCTGATCGGCAACGCGGCGGCCAACGATCT
GATCGGCGGTGCCGGCAACGACATCATTTATGGCGGTGGCGGCGGTGATTCGCTGTGGGGCGGTGAAGGCGCAGACACCT
TCGTGTTCGGCGCGGCCAGCGACTCGACCATGACCGCGCCGGACTGGATCATGGATTTCACCAGCGGCCTGGACAAGATC
GACCTGTCGGGCATCGCTGGGTTCGCCACCGGCGCAGCCACGCTGAACTTCGTCAGCGGCTTCACTGGCCACGCCGGCGA
CGCAATCCTCACGTACTTCGAACAGACCAACCAGACCAGCCTGATGATCGACCTCACAGGCCAGGGCTCGGTGGACTTCG
CGGTGGGTGTGGTGGGGCAGGCGGTGGCGACCGATATCGTCGCGTGA

Upstream 100 bases:

>100_bases
CAGGTTCAATCTGCCTGACAAGGCGAGTGACAGGACGATCTCGCCAGAAGATCGCCGTTTTCTGTCTGACACTGACTCTT
CAGAAACAAGGACGTACACC

Downstream 100 bases:

>100_bases
TCTGAGTCCAAAAAAAACCGCAGTCCTTCACAGGCTGCGGTTTTTTTGTTTTCGGACATCGCTCCACGATAGTGAAATCC
GTTACTGCTCGGTCTCGAGA

Product: epralysin

Products: NA

Alternate protein names: AP [H]

Number of amino acids: Translated: 468; Mature: 467

Protein sequence:

>468_residues
MSQPSSQASSAYTAVDTFSHLYDRGTGTVNGKPSFTADQAADEILRKGMSWQDKNADGKIDLTYTFLTDKPSNYNAKLGN
FSEFSAQQKAQAVLSMQSWSDVAKVTFTEGKGGDGHMTFGNYDVSTGGAAFAYLPQGSSYDGQSWYLINDQYQVNKTPDA
NNYGRQTLTHEIGHTLGLSHPGAYNAGNGNPTYGDAKYAEDTRGYSLMSYWSEANTDQNFSKDGSGAYASAPLMDDIVAV
QKLYGANFETRADNTVYGFNSNADRDFYSATSNTSKVVFSVWDGGGNDTLDFSGFNQNQKINLNEGSFSDVGGLVGNVSI
AHGVTVENAIGGSGSDLLIGNAAANDLIGGAGNDIIYGGGGGDSLWGGEGADTFVFGAASDSTMTAPDWIMDFTSGLDKI
DLSGIAGFATGAATLNFVSGFTGHAGDAILTYFEQTNQTSLMIDLTGQGSVDFAVGVVGQAVATDIVA

Sequences:

>Translated_468_residues
MSQPSSQASSAYTAVDTFSHLYDRGTGTVNGKPSFTADQAADEILRKGMSWQDKNADGKIDLTYTFLTDKPSNYNAKLGN
FSEFSAQQKAQAVLSMQSWSDVAKVTFTEGKGGDGHMTFGNYDVSTGGAAFAYLPQGSSYDGQSWYLINDQYQVNKTPDA
NNYGRQTLTHEIGHTLGLSHPGAYNAGNGNPTYGDAKYAEDTRGYSLMSYWSEANTDQNFSKDGSGAYASAPLMDDIVAV
QKLYGANFETRADNTVYGFNSNADRDFYSATSNTSKVVFSVWDGGGNDTLDFSGFNQNQKINLNEGSFSDVGGLVGNVSI
AHGVTVENAIGGSGSDLLIGNAAANDLIGGAGNDIIYGGGGGDSLWGGEGADTFVFGAASDSTMTAPDWIMDFTSGLDKI
DLSGIAGFATGAATLNFVSGFTGHAGDAILTYFEQTNQTSLMIDLTGQGSVDFAVGVVGQAVATDIVA
>Mature_467_residues
SQPSSQASSAYTAVDTFSHLYDRGTGTVNGKPSFTADQAADEILRKGMSWQDKNADGKIDLTYTFLTDKPSNYNAKLGNF
SEFSAQQKAQAVLSMQSWSDVAKVTFTEGKGGDGHMTFGNYDVSTGGAAFAYLPQGSSYDGQSWYLINDQYQVNKTPDAN
NYGRQTLTHEIGHTLGLSHPGAYNAGNGNPTYGDAKYAEDTRGYSLMSYWSEANTDQNFSKDGSGAYASAPLMDDIVAVQ
KLYGANFETRADNTVYGFNSNADRDFYSATSNTSKVVFSVWDGGGNDTLDFSGFNQNQKINLNEGSFSDVGGLVGNVSIA
HGVTVENAIGGSGSDLLIGNAAANDLIGGAGNDIIYGGGGGDSLWGGEGADTFVFGAASDSTMTAPDWIMDFTSGLDKID
LSGIAGFATGAATLNFVSGFTGHAGDAILTYFEQTNQTSLMIDLTGQGSVDFAVGVVGQAVATDIVA

Specific function: Unknown

COG id: COG2931

COG function: function code Q; RTX toxins and related Ca2+-binding proteins

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 hemolysin-type calcium-binding repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018511
- InterPro:   IPR001343
- InterPro:   IPR016294
- InterPro:   IPR013858
- InterPro:   IPR006026
- InterPro:   IPR011049 [H]

Pfam domain/function: PF00353 HemolysinCabind; PF08548 Peptidase_M10_C [H]

EC number: NA

Molecular weight: Translated: 49083; Mature: 48952

Theoretical pI: Translated: 4.05; Mature: 4.05

Prosite motif: PS01098 LIPASE_GDSL_SER ; PS00142 ZINC_PROTEASE ; PS00330 HEMOLYSIN_CALCIUM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQPSSQASSAYTAVDTFSHLYDRGTGTVNGKPSFTADQAADEILRKGMSWQDKNADGKI
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEE
DLTYTFLTDKPSNYNAKLGNFSEFSAQQKAQAVLSMQSWSDVAKVTFTEGKGGDGHMTFG
EEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCEEEC
NYDVSTGGAAFAYLPQGSSYDGQSWYLINDQYQVNKTPDANNYGRQTLTHEIGHTLGLSH
CEEECCCCEEEEECCCCCCCCCCEEEEECCEEEECCCCCCCCCCHHHHHHHHHHHHCCCC
PGAYNAGNGNPTYGDAKYAEDTRGYSLMSYWSEANTDQNFSKDGSGAYASAPLMDDIVAV
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCEECCCHHHHHHHH
QKLYGANFETRADNTVYGFNSNADRDFYSATSNTSKVVFSVWDGGGNDTLDFSGFNQNQK
HHHHCCCCCCCCCCEEEECCCCCCCCHHCCCCCCCEEEEEEECCCCCCCEEECCCCCCCE
INLNEGSFSDVGGLVGNVSIAHGVTVENAIGGSGSDLLIGNAAANDLIGGAGNDIIYGGG
EEECCCCCHHHHHHHCCEEEECCCEEECCCCCCCCEEEEECCCHHHCCCCCCCCEEEECC
GGDSLWGGEGADTFVFGAASDSTMTAPDWIMDFTSGLDKIDLSGIAGFATGAATLNFVSG
CCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHCC
FTGHAGDAILTYFEQTNQTSLMIDLTGQGSVDFAVGVVGQAVATDIVA
CCCCCCCCEEEEECCCCCEEEEEEECCCCCCEEHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SQPSSQASSAYTAVDTFSHLYDRGTGTVNGKPSFTADQAADEILRKGMSWQDKNADGKI
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEE
DLTYTFLTDKPSNYNAKLGNFSEFSAQQKAQAVLSMQSWSDVAKVTFTEGKGGDGHMTFG
EEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCEEEC
NYDVSTGGAAFAYLPQGSSYDGQSWYLINDQYQVNKTPDANNYGRQTLTHEIGHTLGLSH
CEEECCCCEEEEECCCCCCCCCCEEEEECCEEEECCCCCCCCCCHHHHHHHHHHHHCCCC
PGAYNAGNGNPTYGDAKYAEDTRGYSLMSYWSEANTDQNFSKDGSGAYASAPLMDDIVAV
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCEECCCHHHHHHHH
QKLYGANFETRADNTVYGFNSNADRDFYSATSNTSKVVFSVWDGGGNDTLDFSGFNQNQK
HHHHCCCCCCCCCCEEEECCCCCCCCHHCCCCCCCEEEEEEECCCCCCCEEECCCCCCCE
INLNEGSFSDVGGLVGNVSIAHGVTVENAIGGSGSDLLIGNAAANDLIGGAGNDIIYGGG
EEECCCCCHHHHHHHCCEEEECCCEEECCCCCCCCEEEEECCCHHHCCCCCCCCEEEECC
GGDSLWGGEGADTFVFGAASDSTMTAPDWIMDFTSGLDKIDLSGIAGFATGAATLNFVSG
CCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHCC
FTGHAGDAILTYFEQTNQTSLMIDLTGQGSVDFAVGVVGQAVATDIVA
CCCCCCCCEEEEECCCCCEEEEEEECCCCCCEEHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1427098; 2123832; 10984043; 8253063; 8690704 [H]