Click here to switch to the map view.

The map label for this gene is btr [H]

Identifier: 77459567

GI number: 77459567

Start: 3820107

End: 3820850

Strand: Direct

Name: btr [H]

Synonym: Pfl01_3345

Alternate gene names: 77459567

Gene position: 3820107-3820850 (Clockwise)

Preceding gene: 77459563

Following gene: 77459569

Centisome position: 59.33

GC content: 59.54

Gene sequence:

>744_bases
GTGGCAGAAACTCGCTCGTATCGCGATCAATACCTCAAAACGGCGTGCTCCCGGTGCAGCGTGCTGGAGCTGTGTCTACC
GCTCGGCTTGAACGGTGGAGAAATCGAGCGTCTGGACACGCTGATCGCCCAGCGACTGAAGGTCAAAAAAGGCGCGGCAC
TCTACCGTGCCGGTGATCCTTTGCGTTCCCTCTATGCCGTGCGGCTGGGGTCATTCAAGACCAGCGTGCTGTCGATCGAT
GGTCGCGAGCAAGTCACCGGGTTCCAGATTGCCGGTGAAATGCTCGGTCTGGATGCCATCAGTTCGGATCTGCACACCTG
CGACGCGTTCGCGCTGGAGGACAGCGAAGTCTGCCCCATCCCTTTTGGCCAGCTGGAAAAACTGGCCCGCGAGCTGCCGT
CACTGCAGCACAACCTGAACAGGATCCTCAGCCGGGAGATCGTTCGCGATCACGACATGCTGATGATCCTGGGCAACATG
AGCTCGGATGAACGCCTGGCAGCGTTTCTGTTGAACCTGTCGCAACGCTTGAGCGCTCGTGGCTATTCGTCGCGCAGCTT
TGTGTTGAAGATGCGTCGTGAGGAAATCGGCTCCTACCTGGGCCTGCGCCTCGAAACCATCTGTCGCGGCATCGCCCACC
TGCGCGACCAAAAACTGGTGGAGATTACCGGCCGCGACGTCACCATTCAGAACATGGACGGCCTCAAGCAGTTGATCGTC
GGCTGCCATCGTCACCCGCAGTGA

Upstream 100 bases:

>100_bases
CCTCGGATCCATTCGTCGTTTAACGGCGGCCGACAAGGCTTTTTCCGTGTCAATGGCGACCCGAGAACTATGATCAACAA
TTCATGGTGAGGGCTTTGCG

Downstream 100 bases:

>100_bases
GCGTGCCGACGGGCCGGACGCGCCTTCACGGGGTAATCGCCACCTTCATCACACCGTCACGCTGGTGTGCAAACAAATCG
TAGGCTGCTTCAATGTCATC

Product: Crp/FNR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MAETRSYRDQYLKTACSRCSVLELCLPLGLNGGEIERLDTLIAQRLKVKKGAALYRAGDPLRSLYAVRLGSFKTSVLSID
GREQVTGFQIAGEMLGLDAISSDLHTCDAFALEDSEVCPIPFGQLEKLARELPSLQHNLNRILSREIVRDHDMLMILGNM
SSDERLAAFLLNLSQRLSARGYSSRSFVLKMRREEIGSYLGLRLETICRGIAHLRDQKLVEITGRDVTIQNMDGLKQLIV
GCHRHPQ

Sequences:

>Translated_247_residues
MAETRSYRDQYLKTACSRCSVLELCLPLGLNGGEIERLDTLIAQRLKVKKGAALYRAGDPLRSLYAVRLGSFKTSVLSID
GREQVTGFQIAGEMLGLDAISSDLHTCDAFALEDSEVCPIPFGQLEKLARELPSLQHNLNRILSREIVRDHDMLMILGNM
SSDERLAAFLLNLSQRLSARGYSSRSFVLKMRREEIGSYLGLRLETICRGIAHLRDQKLVEITGRDVTIQNMDGLKQLIV
GCHRHPQ
>Mature_246_residues
AETRSYRDQYLKTACSRCSVLELCLPLGLNGGEIERLDTLIAQRLKVKKGAALYRAGDPLRSLYAVRLGSFKTSVLSIDG
REQVTGFQIAGEMLGLDAISSDLHTCDAFALEDSEVCPIPFGQLEKLARELPSLQHNLNRILSREIVRDHDMLMILGNMS
SDERLAAFLLNLSQRLSARGYSSRSFVLKMRREEIGSYLGLRLETICRGIAHLRDQKLVEITGRDVTIQNMDGLKQLIVG
CHRHPQ

Specific function: May regulate gene expression in response to changes in oxygen levels or to changes in the redox potential of the bacterial environment [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=223, Percent_Identity=43.9461883408072, Blast_Score=207, Evalue=5e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 27674; Mature: 27542

Theoretical pI: Translated: 8.29; Mature: 8.29

Prosite motif: PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAETRSYRDQYLKTACSRCSVLELCLPLGLNGGEIERLDTLIAQRLKVKKGAALYRAGDP
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHCCCCH
LRSLYAVRLGSFKTSVLSIDGREQVTGFQIAGEMLGLDAISSDLHTCDAFALEDSEVCPI
HHHHHHHHHCCHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCC
PFGQLEKLARELPSLQHNLNRILSREIVRDHDMLMILGNMSSDERLAAFLLNLSQRLSAR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHC
GYSSRSFVLKMRREEIGSYLGLRLETICRGIAHLRDQKLVEITGRDVTIQNMDGLKQLIV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEECCHHHHHHHHH
GCHRHPQ
HHHCCCC
>Mature Secondary Structure 
AETRSYRDQYLKTACSRCSVLELCLPLGLNGGEIERLDTLIAQRLKVKKGAALYRAGDP
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHCCCCH
LRSLYAVRLGSFKTSVLSIDGREQVTGFQIAGEMLGLDAISSDLHTCDAFALEDSEVCPI
HHHHHHHHHCCHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCC
PFGQLEKLARELPSLQHNLNRILSREIVRDHDMLMILGNMSSDERLAAFLLNLSQRLSAR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHC
GYSSRSFVLKMRREEIGSYLGLRLETICRGIAHLRDQKLVEITGRDVTIQNMDGLKQLIV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEECCHHHHHHHHH
GCHRHPQ
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7693656; 12910271 [H]