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The map label for this gene is aldH [H]

Identifier: 77459495

GI number: 77459495

Start: 3754796

End: 3756361

Strand: Direct

Name: aldH [H]

Synonym: Pfl01_3273

Alternate gene names: 77459495

Gene position: 3754796-3756361 (Clockwise)

Preceding gene: 77459494

Following gene: 77459498

Centisome position: 58.32

GC content: 64.05

Gene sequence:

>1566_bases
ATGACTCTGACCGGCCACCTGCTGATTGGCGCCGCTGACGTCCCCGCTACCGAGGGCACGATGAAGGCGCTGAACCCGGC
AACCAACCAATTGCTCGAACCGGAATTCGCCCTCGGCGGTGCGTCGCAGATCGATCAGGCGGCAACCCTCGCTGATGCGG
CCTTCGACAGCTACAGCCACACCTCGCTGGCCGAGCGTGCGGCGTTTCTGGAAAGCATCGCCGACAACCTCGACGCCGTC
CGTGAGGAGCTGGCCGCCCGCGCCGCACTGGAAACCGGCCTGCCCCAGGCACAACTGGAGGGCGAAGCCGCCAAGGCCGC
CACCCAGTTCCGCCAGTTCGCCGACGTGGTGCGCAAGGGTCGCTTCCTGCAATTGGCGATCGACCCGGCGCAACCCGATC
GCCAGCCGCGGCCACGGATGGATCATCGCCTGCAAAAAGTCGCCATCGGCCCGGTGGCGATCTTCGGAGCAAGCAATTTT
CCGATCTCCTATTCAGTGGCCGGCGGTGACACCGCGTCGGCACTCGCGGCCGGTGCAACGGTGATTCTCAAGGCGCATAA
CGCGCATCCCGGTGCCTCGGAAATCCAGGCGCGCGCCATCCGTAAAGCGGTGCAAATGCACGGTCTGCACGAAGGGGTTT
TCTCCATGGTGCGCGGTGGTGGCAATGCCATCGGTGAGGCGCTGGTCGATCATCCTTTGATTAAAGCGGTGACGTTCACC
GGTTCAGAGGTGGGCGGCATGGCGCTTTATCGTCGCGCGCAATTACGGCCTGATCCGATCCCGGTGTTCACCGAAATGAC
CAGCGTCAACCCGACGTTCATTCTGCCCGCAGCGCTGTCCGCGCGTGGCGGTGAAATCGGCGATGGCTTTGTCGAGCGGA
TGCTGGTGAATGTCGGGCAGGCCTGTCTGTGTCCGTCGATCCTGATCGCGGTCGAGGGCGAAGGTCTGCAAGCGTTGCGC
AGCGCCATGATCAAGCGGGTCAGTGCAGCGTCGGCGCGTACGATGCTGACGCCGGGGATTCACGGTTCATACGTCAAAGG
GCTGGTGGCAATGGAAAGCGTGGGGGCCAATCTGGTGGCGGTCGGCGCGCCGGCGGATGGTCAGTTTGAGGGACGCTCGG
CGTTGTTGGAAGTTGACGGCCAAGGCCTGCTCAGCGAACCGGCGCTGGCCCATGAAGTGTTCGGTCCGGCGGCGCTGTTG
GTAACGGTCAGGGATGATGAAGAGTTGCTGGCGGTCGCCCGTTCGTTCAAGGGTCAACTGAGCGCAGCCATTCACCTTGA
AGACCGCGATCTGGATCTGGCCCGGCGTCTGCTACCGATCCTCGAGCGCCGCACCGGACGCATCGTGGTCAACGCTTTCG
CCCATCCGCAGGAAGTGACCTTCGCCACCGTACACGGCGGGCCGTTCCCGGCCACCTCGGACAGCCGTTTCACCTCGGTC
GGCATGACCTCGATCGAGCGCTTTTTGCGGCCGGTGGCGTATCAGGGCTTTCCCGATGCATTACTGCCGGAGGTGTTGCG
CGACGCCAATCCACTCGATCTGCCCCGCAGCATCGACGGCCAATAA

Upstream 100 bases:

>100_bases
TGATGCACGCCGCCCATGAACTCAACGGTCCGACGTTCGCCCATGTCATCACCACTACAGACGAACTGATCGCCAACCTT
CAGTCGCAAGGTGACGCAAA

Downstream 100 bases:

>100_bases
AAAATGCCCGGTTCGGCGGATCACCGAATCGGGCATGCTTGTTCAATCAAATAAGCAGGTCCTCATAGAAAGCGCCGTAC
GGAAGCTCGGGGTGTTCGAT

Product: aldehyde dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 521; Mature: 520

Protein sequence:

>521_residues
MTLTGHLLIGAADVPATEGTMKALNPATNQLLEPEFALGGASQIDQAATLADAAFDSYSHTSLAERAAFLESIADNLDAV
REELAARAALETGLPQAQLEGEAAKAATQFRQFADVVRKGRFLQLAIDPAQPDRQPRPRMDHRLQKVAIGPVAIFGASNF
PISYSVAGGDTASALAAGATVILKAHNAHPGASEIQARAIRKAVQMHGLHEGVFSMVRGGGNAIGEALVDHPLIKAVTFT
GSEVGGMALYRRAQLRPDPIPVFTEMTSVNPTFILPAALSARGGEIGDGFVERMLVNVGQACLCPSILIAVEGEGLQALR
SAMIKRVSAASARTMLTPGIHGSYVKGLVAMESVGANLVAVGAPADGQFEGRSALLEVDGQGLLSEPALAHEVFGPAALL
VTVRDDEELLAVARSFKGQLSAAIHLEDRDLDLARRLLPILERRTGRIVVNAFAHPQEVTFATVHGGPFPATSDSRFTSV
GMTSIERFLRPVAYQGFPDALLPEVLRDANPLDLPRSIDGQ

Sequences:

>Translated_521_residues
MTLTGHLLIGAADVPATEGTMKALNPATNQLLEPEFALGGASQIDQAATLADAAFDSYSHTSLAERAAFLESIADNLDAV
REELAARAALETGLPQAQLEGEAAKAATQFRQFADVVRKGRFLQLAIDPAQPDRQPRPRMDHRLQKVAIGPVAIFGASNF
PISYSVAGGDTASALAAGATVILKAHNAHPGASEIQARAIRKAVQMHGLHEGVFSMVRGGGNAIGEALVDHPLIKAVTFT
GSEVGGMALYRRAQLRPDPIPVFTEMTSVNPTFILPAALSARGGEIGDGFVERMLVNVGQACLCPSILIAVEGEGLQALR
SAMIKRVSAASARTMLTPGIHGSYVKGLVAMESVGANLVAVGAPADGQFEGRSALLEVDGQGLLSEPALAHEVFGPAALL
VTVRDDEELLAVARSFKGQLSAAIHLEDRDLDLARRLLPILERRTGRIVVNAFAHPQEVTFATVHGGPFPATSDSRFTSV
GMTSIERFLRPVAYQGFPDALLPEVLRDANPLDLPRSIDGQ
>Mature_520_residues
TLTGHLLIGAADVPATEGTMKALNPATNQLLEPEFALGGASQIDQAATLADAAFDSYSHTSLAERAAFLESIADNLDAVR
EELAARAALETGLPQAQLEGEAAKAATQFRQFADVVRKGRFLQLAIDPAQPDRQPRPRMDHRLQKVAIGPVAIFGASNFP
ISYSVAGGDTASALAAGATVILKAHNAHPGASEIQARAIRKAVQMHGLHEGVFSMVRGGGNAIGEALVDHPLIKAVTFTG
SEVGGMALYRRAQLRPDPIPVFTEMTSVNPTFILPAALSARGGEIGDGFVERMLVNVGQACLCPSILIAVEGEGLQALRS
AMIKRVSAASARTMLTPGIHGSYVKGLVAMESVGANLVAVGAPADGQFEGRSALLEVDGQGLLSEPALAHEVFGPAALLV
TVRDDEELLAVARSFKGQLSAAIHLEDRDLDLARRLLPILERRTGRIVVNAFAHPQEVTFATVHGGPFPATSDSRFTSVG
MTSIERFLRPVAYQGFPDALLPEVLRDANPLDLPRSIDGQ

Specific function: Catalyzes the oxidation of long-chain aliphatic aldehydes to acids. May be implicated in controlling luminescence as it catalyzes the oxidation of the fatty aldehyde substrate for the light-emitting reaction [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI12007648, Length=441, Percent_Identity=24.4897959183673, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI21614513, Length=510, Percent_Identity=23.3333333333333, Blast_Score=70, Evalue=5e-12,
Organism=Escherichia coli, GI87082295, Length=479, Percent_Identity=27.5574112734864, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788042, Length=309, Percent_Identity=30.7443365695793, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1787558, Length=481, Percent_Identity=27.4428274428274, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1789015, Length=421, Percent_Identity=25.6532066508314, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI87081896, Length=459, Percent_Identity=25.4901960784314, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1786504, Length=243, Percent_Identity=30.4526748971193, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17551164, Length=458, Percent_Identity=23.3624454148472, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI133930964, Length=443, Percent_Identity=23.7020316027088, Blast_Score=72, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6323822, Length=255, Percent_Identity=30.9803921568627, Blast_Score=80, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6324950, Length=471, Percent_Identity=21.8683651804671, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6319478, Length=255, Percent_Identity=26.2745098039216, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI281362580, Length=445, Percent_Identity=24.7191011235955, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI62472918, Length=445, Percent_Identity=24.7191011235955, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI62472926, Length=445, Percent_Identity=24.7191011235955, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI62472936, Length=445, Percent_Identity=24.7191011235955, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21356737, Length=445, Percent_Identity=24.7191011235955, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24585660, Length=229, Percent_Identity=25.3275109170306, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.4 [H]

Molecular weight: Translated: 54888; Mature: 54757

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLTGHLLIGAADVPATEGTMKALNPATNQLLEPEFALGGASQIDQAATLADAAFDSYSH
CCEECEEEEEECCCCCCCCHHHHCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCH
TSLAERAAFLESIADNLDAVREELAARAALETGLPQAQLEGEAAKAATQFRQFADVVRKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHCC
RFLQLAIDPAQPDRQPRPRMDHRLQKVAIGPVAIFGASNFPISYSVAGGDTASALAAGAT
CEEEEEECCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCEEEEECCCCHHHHHHCCCE
VILKAHNAHPGASEIQARAIRKAVQMHGLHEGVFSMVRGGGNAIGEALVDHPLIKAVTFT
EEEEECCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCHHHHHHHHCCHHHEEEEEC
GSEVGGMALYRRAQLRPDPIPVFTEMTSVNPTFILPAALSARGGEIGDGFVERMLVNVGQ
CCCCCHHHHHHHHCCCCCCCCCEEHHCCCCCCEEEECHHCCCCCCCCHHHHHHHHHHCCC
ACLCPSILIAVEGEGLQALRSAMIKRVSAASARTMLTPGIHGSYVKGLVAMESVGANLVA
HHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHCCCCEEE
VGAPADGQFEGRSALLEVDGQGLLSEPALAHEVFGPAALLVTVRDDEELLAVARSFKGQL
EECCCCCCCCCCEEEEEECCCCCCCCCHHHHHHCCCEEEEEEECCCHHHHHHHHHHCCCC
SAAIHLEDRDLDLARRLLPILERRTGRIVVNAFAHPQEVTFATVHGGPFPATSDSRFTSV
EEEEEECCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCCCCCCCCCCCCHHH
GMTSIERFLRPVAYQGFPDALLPEVLRDANPLDLPRSIDGQ
HHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
TLTGHLLIGAADVPATEGTMKALNPATNQLLEPEFALGGASQIDQAATLADAAFDSYSH
CEECEEEEEECCCCCCCCHHHHCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCH
TSLAERAAFLESIADNLDAVREELAARAALETGLPQAQLEGEAAKAATQFRQFADVVRKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHCC
RFLQLAIDPAQPDRQPRPRMDHRLQKVAIGPVAIFGASNFPISYSVAGGDTASALAAGAT
CEEEEEECCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCEEEEECCCCHHHHHHCCCE
VILKAHNAHPGASEIQARAIRKAVQMHGLHEGVFSMVRGGGNAIGEALVDHPLIKAVTFT
EEEEECCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCHHHHHHHHCCHHHEEEEEC
GSEVGGMALYRRAQLRPDPIPVFTEMTSVNPTFILPAALSARGGEIGDGFVERMLVNVGQ
CCCCCHHHHHHHHCCCCCCCCCEEHHCCCCCCEEEECHHCCCCCCCCHHHHHHHHHHCCC
ACLCPSILIAVEGEGLQALRSAMIKRVSAASARTMLTPGIHGSYVKGLVAMESVGANLVA
HHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHCCCCEEE
VGAPADGQFEGRSALLEVDGQGLLSEPALAHEVFGPAALLVTVRDDEELLAVARSFKGQL
EECCCCCCCCCCEEEEEECCCCCCCCCHHHHHHCCCEEEEEEECCCHHHHHHHHHHCCCC
SAAIHLEDRDLDLARRLLPILERRTGRIVVNAFAHPQEVTFATVHGGPFPATSDSRFTSV
EEEEEECCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCCCCCCCCCCCCHHH
GMTSIERFLRPVAYQGFPDALLPEVLRDANPLDLPRSIDGQ
HHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8527447; 10903148 [H]