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The map label for this gene is aldH [H]

Identifier: 77459446

GI number: 77459446

Start: 3703723

End: 3705303

Strand: Reverse

Name: aldH [H]

Synonym: Pfl01_3224

Alternate gene names: 77459446

Gene position: 3705303-3703723 (Counterclockwise)

Preceding gene: 77459447

Following gene: 77459445

Centisome position: 57.55

GC content: 63.82

Gene sequence:

>1581_bases
ATGACTCAGATTCTCGGTCACAACTACATCGGCGGTCGTCGCAGCGCGGCGGGCAACGTCAAGCTGCAAAGCGTCGACGC
CACTACGGGCGAAGCACTGCCCCACGATTTCATTCAGGCCACGGAAGCGGAAGTCGACGCCGCCGCAAAAGCCGCTGCGG
CGGCGTATCCGGCGTATCGCAGCCTCAGCGCCGAACGCCGCGCGCAGTTTCTCGATGCGATTGCCGATGAGCTGGATGCG
CTGGGCGATGATTTCGTCGCCGTGGTCTGCCGCGAGACCGCACTGCCGTCCGGGCGAATTCAAGGTGAAAGAGGTCGCAC
CAGTGGCCAGATGCGCTTGTTCGCCAAAGTCCTGCGACGCGGTGATTTCTACGGTGCGCGCATCGACCTGCCGTTGCCCG
ATCGTCAGCCGCTGCCGCGTCCGGATCTGCGCCAGTACCGCATCGGCCTCGGCCCGGTGGCGGTGTTCGGTGCAAGCAAC
TTTCCACTGGCATTCTCCACCGCCGGCGGTGATACCGCGTCGGCGCTGGCGGCCGGTTGCCCGGTGGTGTTCAAGGCCCA
CAGCGGTCATATGGCTACGGCCGAACTCGTCGCTGATGCGCTGATCCGCGCGGCGGAAAAAACCGCCATGCCGGCCGGTG
TGTTCAACATGATCTACGGCGGTGGCGTCGGCGAATGGCTGGTCAAGCATCCGGCTATTCAGGCCGTGGGTTTCACCGGT
TCGCTGCGAGGCGGACGGGCACTGTGTGACATGGCCGCCACGCGCCCTCAACCGATTCCGGTGTTCGCCGAGATGTCGAG
CATCAACCCGGTGATCGTATTGCCCCAGGCTTTGGCCGTGCGTTCGGACACCGTCGCTCGCGATCTGACTGCGTCGGTGG
TGCAGGGCTGCGGTCAGTTCTGTACCAATCCGGGTCTGGTGATCGGCATCCGTTCGCCACAGTTCACCGCGTTTGTTGAG
CAAGTCGCGGCGCTGATCGGAGATCAAGCGGCGCAAACCATGCTCAATGCCGGCACCCTCGGCAGCTACGGCAAAGGCCT
GGAAAAACTCCTGGCCCACGCCGGCATCGAGCATCTGGCGGGCAATCCGCAACAGGGCAATCAGGCGCAGCCGCAGTTGT
TCAAGGCCGACGTCAGCCTGTTGATCGATGGCGATGAAGTGCTGCAGGAAGAAGTGTTCGGCCCGACTTCGGTGATCGTC
GAAGTGGCCGACAAGGCGCAGCTGAGTGCGGCGTTGCAGGGCCTGCATGGGCAACTGACGGCGACAATTATCGGCGAACA
GGCGGATTTCGAACGCTTCCCGGAGCTGACGCCATTGCTGGAGCAGAAGGTCGGTCGGATCCTGCTCAACGGTTATCCGA
CCGGTGTTGAGGTTTGTGATTCGATGGTGCACGGCGGGCCGTATCCGGCGACGTCCGATGCCCGCGGCACCTCGGTGGGT
ACGTTGGCGATCGATCGTTTCCTGCGCCCGGTGTGCTTCCAGAACTACCCCGACAGCCTGCTGCCGGAACCGCTGAAAAA
CGCCAACCCGCTGCGCATTCAGCGGCTGGTCGACGGCAAGCCATCGCGCGAAGCCCTCTGA

Upstream 100 bases:

>100_bases
AATCAGCCAGGCTGAATTCGGCGCACCGCTGGTCAACGGCATCGCCCCGGTCGCAGCGGCATTCGAACCGGACAGCATCG
GCACCCTTTAAGGAGATCTC

Downstream 100 bases:

>100_bases
CTCACGCCGCATGATCGTTCCCGCGAAGGGCGTGGGAGCGATCAAACGCGGGGCTTTGAGCTATCATTGGCCCTTTCCCC
CCTGAAAGACATGATTGCCA

Product: aldehyde dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 526; Mature: 525

Protein sequence:

>526_residues
MTQILGHNYIGGRRSAAGNVKLQSVDATTGEALPHDFIQATEAEVDAAAKAAAAAYPAYRSLSAERRAQFLDAIADELDA
LGDDFVAVVCRETALPSGRIQGERGRTSGQMRLFAKVLRRGDFYGARIDLPLPDRQPLPRPDLRQYRIGLGPVAVFGASN
FPLAFSTAGGDTASALAAGCPVVFKAHSGHMATAELVADALIRAAEKTAMPAGVFNMIYGGGVGEWLVKHPAIQAVGFTG
SLRGGRALCDMAATRPQPIPVFAEMSSINPVIVLPQALAVRSDTVARDLTASVVQGCGQFCTNPGLVIGIRSPQFTAFVE
QVAALIGDQAAQTMLNAGTLGSYGKGLEKLLAHAGIEHLAGNPQQGNQAQPQLFKADVSLLIDGDEVLQEEVFGPTSVIV
EVADKAQLSAALQGLHGQLTATIIGEQADFERFPELTPLLEQKVGRILLNGYPTGVEVCDSMVHGGPYPATSDARGTSVG
TLAIDRFLRPVCFQNYPDSLLPEPLKNANPLRIQRLVDGKPSREAL

Sequences:

>Translated_526_residues
MTQILGHNYIGGRRSAAGNVKLQSVDATTGEALPHDFIQATEAEVDAAAKAAAAAYPAYRSLSAERRAQFLDAIADELDA
LGDDFVAVVCRETALPSGRIQGERGRTSGQMRLFAKVLRRGDFYGARIDLPLPDRQPLPRPDLRQYRIGLGPVAVFGASN
FPLAFSTAGGDTASALAAGCPVVFKAHSGHMATAELVADALIRAAEKTAMPAGVFNMIYGGGVGEWLVKHPAIQAVGFTG
SLRGGRALCDMAATRPQPIPVFAEMSSINPVIVLPQALAVRSDTVARDLTASVVQGCGQFCTNPGLVIGIRSPQFTAFVE
QVAALIGDQAAQTMLNAGTLGSYGKGLEKLLAHAGIEHLAGNPQQGNQAQPQLFKADVSLLIDGDEVLQEEVFGPTSVIV
EVADKAQLSAALQGLHGQLTATIIGEQADFERFPELTPLLEQKVGRILLNGYPTGVEVCDSMVHGGPYPATSDARGTSVG
TLAIDRFLRPVCFQNYPDSLLPEPLKNANPLRIQRLVDGKPSREAL
>Mature_525_residues
TQILGHNYIGGRRSAAGNVKLQSVDATTGEALPHDFIQATEAEVDAAAKAAAAAYPAYRSLSAERRAQFLDAIADELDAL
GDDFVAVVCRETALPSGRIQGERGRTSGQMRLFAKVLRRGDFYGARIDLPLPDRQPLPRPDLRQYRIGLGPVAVFGASNF
PLAFSTAGGDTASALAAGCPVVFKAHSGHMATAELVADALIRAAEKTAMPAGVFNMIYGGGVGEWLVKHPAIQAVGFTGS
LRGGRALCDMAATRPQPIPVFAEMSSINPVIVLPQALAVRSDTVARDLTASVVQGCGQFCTNPGLVIGIRSPQFTAFVEQ
VAALIGDQAAQTMLNAGTLGSYGKGLEKLLAHAGIEHLAGNPQQGNQAQPQLFKADVSLLIDGDEVLQEEVFGPTSVIVE
VADKAQLSAALQGLHGQLTATIIGEQADFERFPELTPLLEQKVGRILLNGYPTGVEVCDSMVHGGPYPATSDARGTSVGT
LAIDRFLRPVCFQNYPDSLLPEPLKNANPLRIQRLVDGKPSREAL

Specific function: Catalyzes the oxidation of long-chain aliphatic aldehydes to acids. May be implicated in controlling luminescence as it catalyzes the oxidation of the fatty aldehyde substrate for the light-emitting reaction [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507229, Length=270, Percent_Identity=29.6296296296296, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI115387104, Length=442, Percent_Identity=24.4343891402715, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI25777721, Length=279, Percent_Identity=28.673835125448, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1789015, Length=390, Percent_Identity=27.6923076923077, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI87081896, Length=423, Percent_Identity=27.1867612293144, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1786504, Length=414, Percent_Identity=27.536231884058, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1787250, Length=432, Percent_Identity=25.6944444444444, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI25143874, Length=319, Percent_Identity=24.4514106583072, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI25143876, Length=319, Percent_Identity=24.4514106583072, Blast_Score=69, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6319478, Length=338, Percent_Identity=25.1479289940828, Blast_Score=80, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6323822, Length=409, Percent_Identity=25.9168704156479, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI281362580, Length=385, Percent_Identity=25.7142857142857, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI62472918, Length=385, Percent_Identity=25.7142857142857, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI62472926, Length=385, Percent_Identity=25.7142857142857, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI62472936, Length=385, Percent_Identity=25.7142857142857, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21356737, Length=385, Percent_Identity=25.7142857142857, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.4 [H]

Molecular weight: Translated: 55519; Mature: 55388

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQILGHNYIGGRRSAAGNVKLQSVDATTGEALPHDFIQATEAEVDAAAKAAAAAYPAYR
CCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SLSAERRAQFLDAIADELDALGDDFVAVVCRETALPSGRIQGERGRTSGQMRLFAKVLRR
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHC
GDFYGARIDLPLPDRQPLPRPDLRQYRIGLGPVAVFGASNFPLAFSTAGGDTASALAAGC
CCCCCCEEECCCCCCCCCCCCCHHHHHCCCCCEEEECCCCCCEEEECCCCCHHHHHHCCC
PVVFKAHSGHMATAELVADALIRAAEKTAMPAGVFNMIYGGGVGEWLVKHPAIQAVGFTG
CEEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHCCCCEEECCCC
SLRGGRALCDMAATRPQPIPVFAEMSSINPVIVLPQALAVRSDTVARDLTASVVQGCGQF
CCCCCHHHHHHHHCCCCCCCCEEHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
CTNPGLVIGIRSPQFTAFVEQVAALIGDQAAQTMLNAGTLGSYGKGLEKLLAHAGIEHLA
HCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCHHHHC
GNPQQGNQAQPQLFKADVSLLIDGDEVLQEEVFGPTSVIVEVADKAQLSAALQGLHGQLT
CCCCCCCCCCCHHHCCCEEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCEEE
ATIIGEQADFERFPELTPLLEQKVGRILLNGYPTGVEVCDSMVHGGPYPATSDARGTSVG
EEEECCCCCHHHCCCHHHHHHHHHHHEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCHH
TLAIDRFLRPVCFQNYPDSLLPEPLKNANPLRIQRLVDGKPSREAL
HHHHHHHHHHHHHCCCCHHCCCCCCCCCCCEEEHHHHCCCCCCCCC
>Mature Secondary Structure 
TQILGHNYIGGRRSAAGNVKLQSVDATTGEALPHDFIQATEAEVDAAAKAAAAAYPAYR
CCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SLSAERRAQFLDAIADELDALGDDFVAVVCRETALPSGRIQGERGRTSGQMRLFAKVLRR
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHC
GDFYGARIDLPLPDRQPLPRPDLRQYRIGLGPVAVFGASNFPLAFSTAGGDTASALAAGC
CCCCCCEEECCCCCCCCCCCCCHHHHHCCCCCEEEECCCCCCEEEECCCCCHHHHHHCCC
PVVFKAHSGHMATAELVADALIRAAEKTAMPAGVFNMIYGGGVGEWLVKHPAIQAVGFTG
CEEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHCCCCEEECCCC
SLRGGRALCDMAATRPQPIPVFAEMSSINPVIVLPQALAVRSDTVARDLTASVVQGCGQF
CCCCCHHHHHHHHCCCCCCCCEEHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
CTNPGLVIGIRSPQFTAFVEQVAALIGDQAAQTMLNAGTLGSYGKGLEKLLAHAGIEHLA
HCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCHHHHC
GNPQQGNQAQPQLFKADVSLLIDGDEVLQEEVFGPTSVIVEVADKAQLSAALQGLHGQLT
CCCCCCCCCCCHHHCCCEEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCEEE
ATIIGEQADFERFPELTPLLEQKVGRILLNGYPTGVEVCDSMVHGGPYPATSDARGTSVG
EEEECCCCCHHHCCCHHHHHHHHHHHEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCHH
TLAIDRFLRPVCFQNYPDSLLPEPLKNANPLRIQRLVDGKPSREAL
HHHHHHHHHHHHHCCCCHHCCCCCCCCCCCEEEHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8527447; 10903148 [H]