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The map label for this gene is mocR [H]

Identifier: 77459424

GI number: 77459424

Start: 3677530

End: 3678966

Strand: Direct

Name: mocR [H]

Synonym: Pfl01_3202

Alternate gene names: 77459424

Gene position: 3677530-3678966 (Clockwise)

Preceding gene: 77459422

Following gene: 77459425

Centisome position: 57.12

GC content: 63.74

Gene sequence:

>1437_bases
ATGGAACTTCATGTCGTGATCAATGGCCGCAAGGACCTGGCCGGTCAGTTGTACCAGCAACTGCGCGGCGCCATTGAATC
CGGGCGCCTGACCGCCGGCACCCAGTTACCGCCCAGCCGTTTGCTCGCCGAGCAATTGGGGATCTCGCGCAAGACCATTT
CCGACACTTACGCGCAGCTCACTTACGAGAATTTCCTCACCGGCGTGATCGGCAAAGGCACTTACGTCAACGCCCGCTCG
ACGCCGGTACAGCGCAAGCAAAGCCATTCCGAACTGGCCAGTTCCGAGGTGATCGAGAGCTGGCGCAATCTGCCGGTGTT
CCTGCGCCATCCGACGCTTGAGGGTTCGCTGCGTTATGACTTCATCGGCGGCGCCACCAGCAAGGGCCAGTTTCCCCATG
ATGACTGGCGCCGCTGCGTCTCTCACGCACTGCGGCAGATGGCCCATTCCAAAGGCTTCTATAGCGTGCCGGAAGGCCTG
CCGGCGCTGCGCAATGCGATTGCCCGGCACATCGCGTTTTCCCGTGGCGTGAACTGCCAGGACGAGGACATCGTGGTCTG
CAACGGTGCGCAACAGGCGCTGGACCTGATCACCCGCGTGCTGATCCGCCCCGGCAGTCTGGTGGCGATGGAAGATCCCG
GCTACCCGCCGGCGCGGCTGCTGTTCGGCACTCACGGGGCGACGGTGGTCGGCGTGCCGGTGGATGCGGAAGGGATTCAG
GTCGAGCGGATTCCCGAGGGCACGCGGCTGATCTATGTGACGCCGTCGCACCAGTTCCCGCTGGGCATGCCGATGAGCCA
GGCGCGACGCGAAGCTTTGCTCGCGCGGGCCCATGAGCTGGGCGCGATCATCATCGAGGACGACTATGACAGCGAATTCC
GCTACGAGGGCCGCCCGACCGATTCGCTGCACAAGCTCGATCAGCGCGGCATCGTCGCCTACGTCGGCACCTTCTCGAAA
ACCTTGCTGCCGGAGCTGCGGCTCGGCTACGCGATCCTGCCGCCAGCGATCCTCGAAGCGGTGATCCGCGCCAAGCAGCT
CACCGACCTGCACGCCTCCACCCTGCCCCAATGGGCGCTGGCCAAGTTCATCGCCGAGGGCTGCCTGCTCAAGCACATCC
GCCGCTGCCACACCATTTATGCCCAGCGCCGCGAGCGGATCCTGGCGCGGATGGCCACCGACCTGTCGCCGTGGCTGCAA
GCCGTGCCGCCCAGCGCCGGGTTTCACATGGCGGTGTTCTGCAAGGTCCCTATCGATTTGCCGCTGGTGATCGAACTGGC
AAAAAAGGTCGAAGTCGGGCTGTACGCCATCGATGGTTTCTATTATCAGCAGCCGGCCAAAAACGGGATGTACTTCGGTT
TCGGCGCCATCGAGACGCTGGACATCGATATCGCGCTAGACCGCCTGCGCGACATTCTGCAACAGGTCGTTGGGTAG

Upstream 100 bases:

>100_bases
GGAGGCCAATTCACGGTTTTTCAAGCACACAACTTCTGCCCCGCCCGCATTCGGGAGTAATCTGGCCGGCACACTCAATC
GCCCGGAGCGCCCCCTCGCA

Downstream 100 bases:

>100_bases
ATTGGACTAAACGATTAACCGCCGATTGGTTATTGGTGATCCGGGGGTGCAGGCCTATCCTGCACAAGCGTTATCCCTCA
ATGAGCAGGATTCGTCCGGC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:

>478_residues
MELHVVINGRKDLAGQLYQQLRGAIESGRLTAGTQLPPSRLLAEQLGISRKTISDTYAQLTYENFLTGVIGKGTYVNARS
TPVQRKQSHSELASSEVIESWRNLPVFLRHPTLEGSLRYDFIGGATSKGQFPHDDWRRCVSHALRQMAHSKGFYSVPEGL
PALRNAIARHIAFSRGVNCQDEDIVVCNGAQQALDLITRVLIRPGSLVAMEDPGYPPARLLFGTHGATVVGVPVDAEGIQ
VERIPEGTRLIYVTPSHQFPLGMPMSQARREALLARAHELGAIIIEDDYDSEFRYEGRPTDSLHKLDQRGIVAYVGTFSK
TLLPELRLGYAILPPAILEAVIRAKQLTDLHASTLPQWALAKFIAEGCLLKHIRRCHTIYAQRRERILARMATDLSPWLQ
AVPPSAGFHMAVFCKVPIDLPLVIELAKKVEVGLYAIDGFYYQQPAKNGMYFGFGAIETLDIDIALDRLRDILQQVVG

Sequences:

>Translated_478_residues
MELHVVINGRKDLAGQLYQQLRGAIESGRLTAGTQLPPSRLLAEQLGISRKTISDTYAQLTYENFLTGVIGKGTYVNARS
TPVQRKQSHSELASSEVIESWRNLPVFLRHPTLEGSLRYDFIGGATSKGQFPHDDWRRCVSHALRQMAHSKGFYSVPEGL
PALRNAIARHIAFSRGVNCQDEDIVVCNGAQQALDLITRVLIRPGSLVAMEDPGYPPARLLFGTHGATVVGVPVDAEGIQ
VERIPEGTRLIYVTPSHQFPLGMPMSQARREALLARAHELGAIIIEDDYDSEFRYEGRPTDSLHKLDQRGIVAYVGTFSK
TLLPELRLGYAILPPAILEAVIRAKQLTDLHASTLPQWALAKFIAEGCLLKHIRRCHTIYAQRRERILARMATDLSPWLQ
AVPPSAGFHMAVFCKVPIDLPLVIELAKKVEVGLYAIDGFYYQQPAKNGMYFGFGAIETLDIDIALDRLRDILQQVVG
>Mature_478_residues
MELHVVINGRKDLAGQLYQQLRGAIESGRLTAGTQLPPSRLLAEQLGISRKTISDTYAQLTYENFLTGVIGKGTYVNARS
TPVQRKQSHSELASSEVIESWRNLPVFLRHPTLEGSLRYDFIGGATSKGQFPHDDWRRCVSHALRQMAHSKGFYSVPEGL
PALRNAIARHIAFSRGVNCQDEDIVVCNGAQQALDLITRVLIRPGSLVAMEDPGYPPARLLFGTHGATVVGVPVDAEGIQ
VERIPEGTRLIYVTPSHQFPLGMPMSQARREALLARAHELGAIIIEDDYDSEFRYEGRPTDSLHKLDQRGIVAYVGTFSK
TLLPELRLGYAILPPAILEAVIRAKQLTDLHASTLPQWALAKFIAEGCLLKHIRRCHTIYAQRRERILARMATDLSPWLQ
AVPPSAGFHMAVFCKVPIDLPLVIELAKKVEVGLYAIDGFYYQQPAKNGMYFGFGAIETLDIDIALDRLRDILQQVVG

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=318, Percent_Identity=24.2138364779874, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI33469970, Length=318, Percent_Identity=24.2138364779874, Blast_Score=92, Evalue=1e-18,
Organism=Escherichia coli, GI1790797, Length=379, Percent_Identity=28.2321899736148, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1787710, Length=382, Percent_Identity=24.6073298429319, Blast_Score=92, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6321236, Length=342, Percent_Identity=22.2222222222222, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 53059; Mature: 53059

Theoretical pI: Translated: 8.35; Mature: 8.35

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELHVVINGRKDLAGQLYQQLRGAIESGRLTAGTQLPPSRLLAEQLGISRKTISDTYAQL
CEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHH
TYENFLTGVIGKGTYVNARSTPVQRKQSHSELASSEVIESWRNLPVFLRHPTLEGSLRYD
HHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEE
FIGGATSKGQFPHDDWRRCVSHALRQMAHSKGFYSVPEGLPALRNAIARHIAFSRGVNCQ
EECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
DEDIVVCNGAQQALDLITRVLIRPGSLVAMEDPGYPPARLLFGTHGATVVGVPVDAEGIQ
CCCEEEECCHHHHHHHHHHHHHCCCCEEEECCCCCCCHHEEEECCCCEEEEECCCCCCCE
VERIPEGTRLIYVTPSHQFPLGMPMSQARREALLARAHELGAIIIEDDYDSEFRYEGRPT
EEECCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCCEECCCCC
DSLHKLDQRGIVAYVGTFSKTLLPELRLGYAILPPAILEAVIRAKQLTDLHASTLPQWAL
HHHHHHHHCCEEEEEHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHCCCHHHH
AKFIAEGCLLKHIRRCHTIYAQRRERILARMATDLSPWLQAVPPSAGFHMAVFCKVPIDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCC
PLVIELAKKVEVGLYAIDGFYYQQPAKNGMYFGFGAIETLDIDIALDRLRDILQQVVG
HHHHHHHHHHHEEEEEECCEEECCCCCCCCEEECCCEEEEEHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MELHVVINGRKDLAGQLYQQLRGAIESGRLTAGTQLPPSRLLAEQLGISRKTISDTYAQL
CEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHH
TYENFLTGVIGKGTYVNARSTPVQRKQSHSELASSEVIESWRNLPVFLRHPTLEGSLRYD
HHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEE
FIGGATSKGQFPHDDWRRCVSHALRQMAHSKGFYSVPEGLPALRNAIARHIAFSRGVNCQ
EECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
DEDIVVCNGAQQALDLITRVLIRPGSLVAMEDPGYPPARLLFGTHGATVVGVPVDAEGIQ
CCCEEEECCHHHHHHHHHHHHHCCCCEEEECCCCCCCHHEEEECCCCEEEEECCCCCCCE
VERIPEGTRLIYVTPSHQFPLGMPMSQARREALLARAHELGAIIIEDDYDSEFRYEGRPT
EEECCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCCEECCCCC
DSLHKLDQRGIVAYVGTFSKTLLPELRLGYAILPPAILEAVIRAKQLTDLHASTLPQWAL
HHHHHHHHCCEEEEEHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHCCCHHHH
AKFIAEGCLLKHIRRCHTIYAQRRERILARMATDLSPWLQAVPPSAGFHMAVFCKVPIDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCC
PLVIELAKKVEVGLYAIDGFYYQQPAKNGMYFGFGAIETLDIDIALDRLRDILQQVVG
HHHHHHHHHHHEEEEEECCEEECCCCCCCCEEECCCEEEEEHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]