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The map label for this gene is ytcJ [H]

Identifier: 77459376

GI number: 77459376

Start: 3621772

End: 3623529

Strand: Direct

Name: ytcJ [H]

Synonym: Pfl01_3154

Alternate gene names: 77459376

Gene position: 3621772-3623529 (Clockwise)

Preceding gene: 77459370

Following gene: 77459377

Centisome position: 56.25

GC content: 62.74

Gene sequence:

>1758_bases
ATGAAAAGATTCATCCCGCTTTTCACAAAAAATCTGCTGATCGCCGCTATGAGTTTTGCCTCGATGGAAGCCATGGCCGC
CACCGATCTGGTGCTGTTCAATGGCAAGATTTTCACCGCCGACCGCGCTCAACCGAAGGTTCAGGCGCTGGCCGTGGAGA
ACGGCAAGGTGCTGAAAGTCGGCAGCGATGCGCAGATCAAGGCCTTGATCGAACCCGGCACCCAGGTCATCGACCTGAAA
GGCCAGGCGCTGATGCCCGGCCTGATCGACAGCCACTCCCACGCAATTTTCGGCGGACTGGAAATGGTCTCGGCCAACAT
GGAAGACGAGGTGGTCGGTCTGGATGAACTGGAAAAACGCCTGCGCGGCTGGCGTGACGACGGCAAGGCCCGGCATGGCG
ATGTGTTGAGCGTGGCCGGCATGAGTTCGGCGTATTGGGCCAAGGCTGAAGCGCTGGGCAAAATCTTCAATAACGGCGAA
TGGACCGACGTGCCGGTGGTGTTCACCGGCAGCGATCACCACACGGCGTGGGCCAACAACGTGATGCTCAAGCGTGCGGG
CATCGACGCCGCGCTGCTGAAAACCCTGCCGGACGCGGAAAAAGACACCCTCGGCAAACTGGCCAACGGTGAACCGAACG
GCTTTGTGGTCGACGCCGGTTGGGATCGGGTTGCCTCGAAAATGCCAGTGCCGAGCCCGGCCGACATGCTCAAAGCCGCG
CAATCGGCGGTGCGTTTCAACAACAGCCTCGGCATCACCGCGTGGATGGACCCCGCCGCCAACGCCGCGCCGGGCGAGCC
GGTGTTCGCCCTCAAGCCCACCGAGAAAACCGTCGGCGTGCTGCCGGCCTACAAGGCCCTGTCGGAAAGCGGCGGCATGA
CTGCCCACGTCGCCGCACTGCTGGTGGCCAATCCGAAAAGCGTCCCGGCCGATCTCGACACCCTCGACAAGGTGCGCCGG
CAGTTTCAGGGCATTCCCAACCTCACGCTGCCGGGGATCAAGATCTTCGCCGACGGCGTGATCGAGTACCCGGCCCAGAG
CGCGGCGATGATCGATCCCTACAGCAACTCGCACAAACAGGGCGAATTGCTGATCGATCCGCAGCATTTCGGCGAACTGG
TCAGTGCCATCGACCAGCGCGGCTGGCTGGTGCACATCCACGCCATCGGCGACCGCGCGGTGCGCGAATCGCTGAACGGC
ATAGCCCAGGCGCGCAAGGACCGGCAAAGCGGCGTAACGCACTCGATCACCCACCTGCAAATGGTCAACCCGAAGGAGTT
CGCCCGCTTCAAGCCGCTGAACGTGATTGCCTCGATGCAACTGCTGTGGGCCAGCGCCGACGACTACACCACCGACATGA
TCAAGCCTTACGTCAGCGCTCTTGCCTTTCGCTATCAATACCCGGCGCATTCGCTGCTCAAACAGGGCGCGACGATTGCC
GGCGCGAGCGACTGGCCGGTGTCCTCGCCGAACCCGTGGAACGCCATGGCCCAGGCCATCACCCGCACCGGGCCGCTGGG
CGTGCTCAACGCCGACGAACGCCTGGACCGTGAAACCATGTTCTACGCCTACACCGCCAACGCGGCGCGGACCATCGGCC
TGGAACAACAGATTGGCTCGCTGAGCCCCGGCAAACAGGCCGATTTCATCGTGCTCGATCGCGACGTGTTCAGCGTCGAT
GACAAAGCCCTGCATGACACCCAGGTGCTGCAAACCTGGTTCGCCGGCCGTCAGGTCTACGCCCCTACCCTCCAATAA

Upstream 100 bases:

>100_bases
TTTTCCATTCAGGCAAAAACGTTTTTCGTGAGGGAGGCGTTCTGTCGGGCGTTGGCAGCCACTAATCTGGCCATCAGACG
CAATAACAAGGAAATGTTCA

Downstream 100 bases:

>100_bases
CAATCGCCGTATCCGCTGCCCGACCCCGCGCCAGCCGCCGGGGTCCGGCGCAGCCTTGCCCGCTTCCTGCCCATAACAAC
CACAACAACGGGACTTCACA

Product: amidohydrolase-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 585; Mature: 585

Protein sequence:

>585_residues
MKRFIPLFTKNLLIAAMSFASMEAMAATDLVLFNGKIFTADRAQPKVQALAVENGKVLKVGSDAQIKALIEPGTQVIDLK
GQALMPGLIDSHSHAIFGGLEMVSANMEDEVVGLDELEKRLRGWRDDGKARHGDVLSVAGMSSAYWAKAEALGKIFNNGE
WTDVPVVFTGSDHHTAWANNVMLKRAGIDAALLKTLPDAEKDTLGKLANGEPNGFVVDAGWDRVASKMPVPSPADMLKAA
QSAVRFNNSLGITAWMDPAANAAPGEPVFALKPTEKTVGVLPAYKALSESGGMTAHVAALLVANPKSVPADLDTLDKVRR
QFQGIPNLTLPGIKIFADGVIEYPAQSAAMIDPYSNSHKQGELLIDPQHFGELVSAIDQRGWLVHIHAIGDRAVRESLNG
IAQARKDRQSGVTHSITHLQMVNPKEFARFKPLNVIASMQLLWASADDYTTDMIKPYVSALAFRYQYPAHSLLKQGATIA
GASDWPVSSPNPWNAMAQAITRTGPLGVLNADERLDRETMFYAYTANAARTIGLEQQIGSLSPGKQADFIVLDRDVFSVD
DKALHDTQVLQTWFAGRQVYAPTLQ

Sequences:

>Translated_585_residues
MKRFIPLFTKNLLIAAMSFASMEAMAATDLVLFNGKIFTADRAQPKVQALAVENGKVLKVGSDAQIKALIEPGTQVIDLK
GQALMPGLIDSHSHAIFGGLEMVSANMEDEVVGLDELEKRLRGWRDDGKARHGDVLSVAGMSSAYWAKAEALGKIFNNGE
WTDVPVVFTGSDHHTAWANNVMLKRAGIDAALLKTLPDAEKDTLGKLANGEPNGFVVDAGWDRVASKMPVPSPADMLKAA
QSAVRFNNSLGITAWMDPAANAAPGEPVFALKPTEKTVGVLPAYKALSESGGMTAHVAALLVANPKSVPADLDTLDKVRR
QFQGIPNLTLPGIKIFADGVIEYPAQSAAMIDPYSNSHKQGELLIDPQHFGELVSAIDQRGWLVHIHAIGDRAVRESLNG
IAQARKDRQSGVTHSITHLQMVNPKEFARFKPLNVIASMQLLWASADDYTTDMIKPYVSALAFRYQYPAHSLLKQGATIA
GASDWPVSSPNPWNAMAQAITRTGPLGVLNADERLDRETMFYAYTANAARTIGLEQQIGSLSPGKQADFIVLDRDVFSVD
DKALHDTQVLQTWFAGRQVYAPTLQ
>Mature_585_residues
MKRFIPLFTKNLLIAAMSFASMEAMAATDLVLFNGKIFTADRAQPKVQALAVENGKVLKVGSDAQIKALIEPGTQVIDLK
GQALMPGLIDSHSHAIFGGLEMVSANMEDEVVGLDELEKRLRGWRDDGKARHGDVLSVAGMSSAYWAKAEALGKIFNNGE
WTDVPVVFTGSDHHTAWANNVMLKRAGIDAALLKTLPDAEKDTLGKLANGEPNGFVVDAGWDRVASKMPVPSPADMLKAA
QSAVRFNNSLGITAWMDPAANAAPGEPVFALKPTEKTVGVLPAYKALSESGGMTAHVAALLVANPKSVPADLDTLDKVRR
QFQGIPNLTLPGIKIFADGVIEYPAQSAAMIDPYSNSHKQGELLIDPQHFGELVSAIDQRGWLVHIHAIGDRAVRESLNG
IAQARKDRQSGVTHSITHLQMVNPKEFARFKPLNVIASMQLLWASADDYTTDMIKPYVSALAFRYQYPAHSLLKQGATIA
GASDWPVSSPNPWNAMAQAITRTGPLGVLNADERLDRETMFYAYTANAARTIGLEQQIGSLSPGKQADFIVLDRDVFSVD
DKALHDTQVLQTWFAGRQVYAPTLQ

Specific function: Catalyzes The Hydrolytic Cleavage Of A Subset Of L- Isoaspartyl (L-Beta-Aspartyl) Dipeptides. Used To Degrade Proteins Damaged By L-Isoaspartyl Residues Formation. The Best Substrate For The Enzyme Reported Thus Far Is Iso-Asp-Leu. [C]

COG id: COG1574

COG function: function code R; Predicted metal-dependent hydrolase with the TIM-barrel fold

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: 3.4.19.- [C]

Molecular weight: Translated: 63310; Mature: 63310

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRFIPLFTKNLLIAAMSFASMEAMAATDLVLFNGKIFTADRAQPKVQALAVENGKVLKV
CCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCEEEECCCCCCCEEEEEECCCCEEEE
GSDAQIKALIEPGTQVIDLKGQALMPGLIDSHSHAIFGGLEMVSANMEDEVVGLDELEKR
CCCCEEEEEECCCCEEEEECCCEECCCHHCCCCCEECCCHHHEECCCCCCEECHHHHHHH
LRGWRDDGKARHGDVLSVAGMSSAYWAKAEALGKIFNNGEWTDVPVVFTGSDHHTAWANN
HCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHCC
VMLKRAGIDAALLKTLPDAEKDTLGKLANGEPNGFVVDAGWDRVASKMPVPSPADMLKAA
EEEEECCCCHHHHHHCCCCCHHHHHHHCCCCCCEEEEECCHHHHHHCCCCCCHHHHHHHH
QSAVRFNNSLGITAWMDPAANAAPGEPVFALKPTEKTVGVLPAYKALSESGGMTAHVAAL
HHHHHHCCCCCEEEEECCCCCCCCCCCEEEECCCCHHHCCCHHHHHHHHCCCCCEEEEEE
LVANPKSVPADLDTLDKVRRQFQGIPNLTLPGIKIFADGVIEYPAQSAAMIDPYSNSHKQ
EEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEECCHHHCCCCCCEEECCCCCCCCC
GELLIDPQHFGELVSAIDQRGWLVHIHAIGDRAVRESLNGIAQARKDRQSGVTHSITHLQ
CCEEECHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEE
MVNPKEFARFKPLNVIASMQLLWASADDYTTDMIKPYVSALAFRYQYPAHSLLKQGATIA
ECCHHHHHHCCCHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCEEE
GASDWPVSSPNPWNAMAQAITRTGPLGVLNADERLDRETMFYAYTANAARTIGLEQQIGS
CCCCCCCCCCCCHHHHHHHHHCCCCCEEECCHHHCCCCEEEEEEECCCHHCCCHHHHHCC
LSPGKQADFIVLDRDVFSVDDKALHDTQVLQTWFAGRQVYAPTLQ
CCCCCCCCEEEEECCEECCCCHHHHHHHHHHHHHCCCEEECCCCC
>Mature Secondary Structure
MKRFIPLFTKNLLIAAMSFASMEAMAATDLVLFNGKIFTADRAQPKVQALAVENGKVLKV
CCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCEEEECCCCCCCEEEEEECCCCEEEE
GSDAQIKALIEPGTQVIDLKGQALMPGLIDSHSHAIFGGLEMVSANMEDEVVGLDELEKR
CCCCEEEEEECCCCEEEEECCCEECCCHHCCCCCEECCCHHHEECCCCCCEECHHHHHHH
LRGWRDDGKARHGDVLSVAGMSSAYWAKAEALGKIFNNGEWTDVPVVFTGSDHHTAWANN
HCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHCC
VMLKRAGIDAALLKTLPDAEKDTLGKLANGEPNGFVVDAGWDRVASKMPVPSPADMLKAA
EEEEECCCCHHHHHHCCCCCHHHHHHHCCCCCCEEEEECCHHHHHHCCCCCCHHHHHHHH
QSAVRFNNSLGITAWMDPAANAAPGEPVFALKPTEKTVGVLPAYKALSESGGMTAHVAAL
HHHHHHCCCCCEEEEECCCCCCCCCCCEEEECCCCHHHCCCHHHHHHHHCCCCCEEEEEE
LVANPKSVPADLDTLDKVRRQFQGIPNLTLPGIKIFADGVIEYPAQSAAMIDPYSNSHKQ
EEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEECCHHHCCCCCCEEECCCCCCCCC
GELLIDPQHFGELVSAIDQRGWLVHIHAIGDRAVRESLNGIAQARKDRQSGVTHSITHLQ
CCEEECHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEE
MVNPKEFARFKPLNVIASMQLLWASADDYTTDMIKPYVSALAFRYQYPAHSLLKQGATIA
ECCHHHHHHCCCHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCEEE
GASDWPVSSPNPWNAMAQAITRTGPLGVLNADERLDRETMFYAYTANAARTIGLEQQIGS
CCCCCCCCCCCCHHHHHHHHHCCCCCEEECCHHHCCCCEEEEEEECCCHHCCCHHHHHCC
LSPGKQADFIVLDRDVFSVDDKALHDTQVLQTWFAGRQVYAPTLQ
CCCCCCCCEEEEECCEECCCCHHHHHHHHHHHHHCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]