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The map label for this gene is hdfR [H]

Identifier: 77459350

GI number: 77459350

Start: 3591446

End: 3592366

Strand: Direct

Name: hdfR [H]

Synonym: Pfl01_3128

Alternate gene names: 77459350

Gene position: 3591446-3592366 (Clockwise)

Preceding gene: 77459349

Following gene: 77459351

Centisome position: 55.78

GC content: 65.04

Gene sequence:

>921_bases
ATGACGCGGTCCCGGGGCTGCCCGTACAATGCGGGCACCTCAACCACCGGCCCGCCCATGGACATCGACCTCGCCCGCAC
CTTTCTGGAAATCGTCCGTCACGGCAGCCTCGCCGCGGCGGCGGAAAAGCTGTTCGTCACGCAAACGGCAATCACCGCCC
GCGTCCAGAAACTCGAAAGCCAGTTGGGCAGCACGCTGTTCGTGCGCAACCGTGCCGGTGCGCGGCTGACCGCCAATGGC
GAGGCTTTCGTGGTCTACGCCAATCAGCTGGTGCAGACCTGGGAAGCGGCGCGCCGCGACCTGCCCTTGCCCGAGGGCTA
TCACAACGTGCTGCACATCGGCGGCGAGGTCAGTCTGTGCAACCCGCTGATGCTCAGTTGGGCCGCTGAGCTGCGGGAGA
AAATCCCCGGCCACGCTTTGCGCATGGACATCCGCGACGGCGAAAACCTGCTGCGCCAGCTCGAATTGGGGGTGCTCGAT
GCGGCGCTGGTCTATCAACCGGAATATTGGCCGGGACTGCAGGTCGAGCAGGTGCTGGAGGAGAAACTGATTCTGGTGAC
CACGCCCGGCCGCCCTGCCCCCTACGTGTACATCGACTGGGGTCCGGACTTCCGTCGCCAGCACGACGCCGCCCTGCCGG
AAAAAGCCAAGGCTGCCCTGAGCTTCAACCTCGGCCCGCTGGCCCTGCAATACATTCTGGAGAACGGCGGCAGCGGCTAT
TTCCGGACCCGGGTCGTGCGCACCTACTTGGAAAGCGGCGCGCTGGAACCGGTGACCAAAGCCCCGGAATTCGGCTATCC
GACCTACCTCGTCTACTCCCGCGACCGCGACTCGGCGATCCTGCAACAGGCGTTCGATCTGCTGCGCGAAGTGATCAAGG
CCGATGACGACTGGTCGCAGCGCTGGAACCCGTTGAGCTGA

Upstream 100 bases:

>100_bases
GTGCCGGAGTTTTGTTTACAAGCGCAAGACTTGCTGCACGCCGGCGCGGTTGGTGGAGGATTGGGCTCGGGTGCGTGAAG
TCGAAGTGGCTGACTGAACA

Downstream 100 bases:

>100_bases
CGGCCGCTATACACCGGAGCATGGCACTTGTGACCTGAAGGTTGCCCCTGCACAAACGGCGGGATCGGCTACGCTGCCGG
GATAACGACAATATCCGCAG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: H-NS-dependent flhDC regulator [H]

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MTRSRGCPYNAGTSTTGPPMDIDLARTFLEIVRHGSLAAAAEKLFVTQTAITARVQKLESQLGSTLFVRNRAGARLTANG
EAFVVYANQLVQTWEAARRDLPLPEGYHNVLHIGGEVSLCNPLMLSWAAELREKIPGHALRMDIRDGENLLRQLELGVLD
AALVYQPEYWPGLQVEQVLEEKLILVTTPGRPAPYVYIDWGPDFRRQHDAALPEKAKAALSFNLGPLALQYILENGGSGY
FRTRVVRTYLESGALEPVTKAPEFGYPTYLVYSRDRDSAILQQAFDLLREVIKADDDWSQRWNPLS

Sequences:

>Translated_306_residues
MTRSRGCPYNAGTSTTGPPMDIDLARTFLEIVRHGSLAAAAEKLFVTQTAITARVQKLESQLGSTLFVRNRAGARLTANG
EAFVVYANQLVQTWEAARRDLPLPEGYHNVLHIGGEVSLCNPLMLSWAAELREKIPGHALRMDIRDGENLLRQLELGVLD
AALVYQPEYWPGLQVEQVLEEKLILVTTPGRPAPYVYIDWGPDFRRQHDAALPEKAKAALSFNLGPLALQYILENGGSGY
FRTRVVRTYLESGALEPVTKAPEFGYPTYLVYSRDRDSAILQQAFDLLREVIKADDDWSQRWNPLS
>Mature_305_residues
TRSRGCPYNAGTSTTGPPMDIDLARTFLEIVRHGSLAAAAEKLFVTQTAITARVQKLESQLGSTLFVRNRAGARLTANGE
AFVVYANQLVQTWEAARRDLPLPEGYHNVLHIGGEVSLCNPLMLSWAAELREKIPGHALRMDIRDGENLLRQLELGVLDA
ALVYQPEYWPGLQVEQVLEEKLILVTTPGRPAPYVYIDWGPDFRRQHDAALPEKAKAALSFNLGPLALQYILENGGSGYF
RTRVVRTYLESGALEPVTKAPEFGYPTYLVYSRDRDSAILQQAFDLLREVIKADDDWSQRWNPLS

Specific function: Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994962, Length=278, Percent_Identity=30.5755395683453, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1787601, Length=179, Percent_Identity=28.4916201117318, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081904, Length=170, Percent_Identity=29.4117647058824, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789173, Length=176, Percent_Identity=29.5454545454545, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020890
- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34211; Mature: 34080

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRSRGCPYNAGTSTTGPPMDIDLARTFLEIVRHGSLAAAAEKLFVTQTAITARVQKLES
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
QLGSTLFVRNRAGARLTANGEAFVVYANQLVQTWEAARRDLPLPEGYHNVLHIGGEVSLC
HHCCEEEEECCCCCEEEECCCEEEEEHHHHHHHHHHHHHCCCCCCCCHHHEEECCCCCHH
NPLMLSWAAELREKIPGHALRMDIRDGENLLRQLELGVLDAALVYQPEYWPGLQVEQVLE
HHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHH
EKLILVTTPGRPAPYVYIDWGPDFRRQHDAALPEKAKAALSFNLGPLALQYILENGGSGY
CCEEEEECCCCCCCEEEEECCCCHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCH
FRTRVVRTYLESGALEPVTKAPEFGYPTYLVYSRDRDSAILQQAFDLLREVIKADDDWSQ
HHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHH
RWNPLS
CCCCCC
>Mature Secondary Structure 
TRSRGCPYNAGTSTTGPPMDIDLARTFLEIVRHGSLAAAAEKLFVTQTAITARVQKLES
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
QLGSTLFVRNRAGARLTANGEAFVVYANQLVQTWEAARRDLPLPEGYHNVLHIGGEVSLC
HHCCEEEEECCCCCEEEECCCEEEEEHHHHHHHHHHHHHCCCCCCCCHHHEEECCCCCHH
NPLMLSWAAELREKIPGHALRMDIRDGENLLRQLELGVLDAALVYQPEYWPGLQVEQVLE
HHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHH
EKLILVTTPGRPAPYVYIDWGPDFRRQHDAALPEKAKAALSFNLGPLALQYILENGGSGY
CCEEEEECCCCCCCEEEEECCCCHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCH
FRTRVVRTYLESGALEPVTKAPEFGYPTYLVYSRDRDSAILQQAFDLLREVIKADDDWSQ
HHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHH
RWNPLS
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA