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The map label for this gene is aroF [H]

Identifier: 77459291

GI number: 77459291

Start: 3511237

End: 3512313

Strand: Direct

Name: aroF [H]

Synonym: Pfl01_3069

Alternate gene names: 77459291

Gene position: 3511237-3512313 (Clockwise)

Preceding gene: 77459284

Following gene: 77459293

Centisome position: 54.54

GC content: 60.54

Gene sequence:

>1077_bases
ATGAACTCGTCCGTTTCTGCTCTGCCACTGTCCACCCTGAACCCTGCCAACGAAGCATTGACCCTGCGTCTGCCGAGTTC
GCTGCAACTCAAACAGCAATTGCCCCTGAGCAATGCGCTGAACCAGCAAGTCGTTGCACACCGCCAGGCGGTCCGCGCGA
TTCTCGATGGCCATGACCCGCGTTTGCTGGTGATCGTCGGCCCCTGCTCGATACACGACCCTGAGTCCGCGCTTGAATAC
GCCAGCAAACTTTCGCATCTGGCCGAAGAAGTCCGTGATGACATGCTGCTGGTGATGCGTGCCTACGTCGAAAAACCTCG
CACCACCGTCGGTTGGAAAGGCCTTGCCTACGACCCTCATCTGGATGGCAGCGACGACATGGCTGCCGGCCTCACCCTGT
CGCGCGAACTGATGCTCGAAATGATCCGCGTCGGACTTCCGATTGCCACCGAACTGCTGCAGCCCATGGCCGCCGGGTAC
TTCGATGACTTGCTGAGCTGGGTCGCCATTGGCGCCCGTACTACCGAGTCCCAGATCCACCGGGAAATGGCCAGTGGACT
GAGCATGCCGGTCGGCTTCAAGAACGGCACCGATGGCGGCGTGACTGTCGCCGTTGACGCGATGCGTTCGGCAGCACATC
CCCATCGTCACTTCGGCGTCGACAGCCAGGGCCACCCGGCAATCATCCAGACCCCGGGCAACCAGGACACACATCTGGTG
CTGCGCGGTGGCCACCAAGGGCCGAACTACGACCGCGAAAGCGTTTCCAGAATCAACGCCGAGTTGAACCGCCTGAAGAT
CCCGAAGCGGATGATGGTTGATTGCAGTCATGCCAACAGTGGCAAGGACCCACTCCGGCAGCCAGGCGTGTTCAACGATG
TGCTGGAGCAACGCTTGAAGGGCGACCGCTCGCTGGTCGGCATGATGCTTGAGTCACACCTGTTTGAAGGATGCCAGCCG
TTGAGCGAGTCGCTTCGGTACGGAGTTTCGATTACCGATGCCTGCCTCGGGTTCGATTCCACCAGGCAGTTGCTGCTGGA
CGCAGCGCATCGCATGCGAAAACAGACCTCAGCCTGA

Upstream 100 bases:

>100_bases
GTGGCAAGCCAACACACGTAGCCAATCCGGCCAATTGTCGAACACCCCAGTAGGGCCGATTGAGCGGGAAGACCCCGCCC
TCCGCCCTGGAAGACCGAAT

Downstream 100 bases:

>100_bases
CAGTGAACACCGCCCTCCGCTGCGCGTTCTCACGGAGGGCGGTGCAGTGTTCACAACAGATGATCACGCCTGCACTTGCA
GCAACATCACCTCGGACTGC

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MNSSVSALPLSTLNPANEALTLRLPSSLQLKQQLPLSNALNQQVVAHRQAVRAILDGHDPRLLVIVGPCSIHDPESALEY
ASKLSHLAEEVRDDMLLVMRAYVEKPRTTVGWKGLAYDPHLDGSDDMAAGLTLSRELMLEMIRVGLPIATELLQPMAAGY
FDDLLSWVAIGARTTESQIHREMASGLSMPVGFKNGTDGGVTVAVDAMRSAAHPHRHFGVDSQGHPAIIQTPGNQDTHLV
LRGGHQGPNYDRESVSRINAELNRLKIPKRMMVDCSHANSGKDPLRQPGVFNDVLEQRLKGDRSLVGMMLESHLFEGCQP
LSESLRYGVSITDACLGFDSTRQLLLDAAHRMRKQTSA

Sequences:

>Translated_358_residues
MNSSVSALPLSTLNPANEALTLRLPSSLQLKQQLPLSNALNQQVVAHRQAVRAILDGHDPRLLVIVGPCSIHDPESALEY
ASKLSHLAEEVRDDMLLVMRAYVEKPRTTVGWKGLAYDPHLDGSDDMAAGLTLSRELMLEMIRVGLPIATELLQPMAAGY
FDDLLSWVAIGARTTESQIHREMASGLSMPVGFKNGTDGGVTVAVDAMRSAAHPHRHFGVDSQGHPAIIQTPGNQDTHLV
LRGGHQGPNYDRESVSRINAELNRLKIPKRMMVDCSHANSGKDPLRQPGVFNDVLEQRLKGDRSLVGMMLESHLFEGCQP
LSESLRYGVSITDACLGFDSTRQLLLDAAHRMRKQTSA
>Mature_358_residues
MNSSVSALPLSTLNPANEALTLRLPSSLQLKQQLPLSNALNQQVVAHRQAVRAILDGHDPRLLVIVGPCSIHDPESALEY
ASKLSHLAEEVRDDMLLVMRAYVEKPRTTVGWKGLAYDPHLDGSDDMAAGLTLSRELMLEMIRVGLPIATELLQPMAAGY
FDDLLSWVAIGARTTESQIHREMASGLSMPVGFKNGTDGGVTVAVDAMRSAAHPHRHFGVDSQGHPAIIQTPGNQDTHLV
LRGGHQGPNYDRESVSRINAELNRLKIPKRMMVDCSHANSGKDPLRQPGVFNDVLEQRLKGDRSLVGMMLESHLFEGCQP
LSESLRYGVSITDACLGFDSTRQLLLDAAHRMRKQTSA

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788953, Length=334, Percent_Identity=53.2934131736527, Blast_Score=364, Evalue=1e-102,
Organism=Escherichia coli, GI1786969, Length=349, Percent_Identity=48.9971346704871, Blast_Score=329, Evalue=2e-91,
Organism=Escherichia coli, GI1787996, Length=338, Percent_Identity=44.9704142011834, Blast_Score=290, Evalue=1e-79,
Organism=Saccharomyces cerevisiae, GI6320240, Length=338, Percent_Identity=46.7455621301775, Blast_Score=329, Evalue=3e-91,
Organism=Saccharomyces cerevisiae, GI6319726, Length=341, Percent_Identity=47.2140762463343, Blast_Score=306, Evalue=3e-84,

Paralogues:

None

Copy number: 2,200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 39137; Mature: 39137

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSSVSALPLSTLNPANEALTLRLPSSLQLKQQLPLSNALNQQVVAHRQAVRAILDGHDP
CCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCC
RLLVIVGPCSIHDPESALEYASKLSHLAEEVRDDMLLVMRAYVEKPRTTVGWKGLAYDPH
EEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
LDGSDDMAAGLTLSRELMLEMIRVGLPIATELLQPMAAGYFDDLLSWVAIGARTTESQIH
CCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
REMASGLSMPVGFKNGTDGGVTVAVDAMRSAAHPHRHFGVDSQGHPAIIQTPGNQDTHLV
HHHHCCCCCCCCCCCCCCCCEEEEHHHHHHHCCCHHHCCCCCCCCCEEEECCCCCCCEEE
LRGGHQGPNYDRESVSRINAELNRLKIPKRMMVDCSHANSGKDPLRQPGVFNDVLEQRLK
EECCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHC
GDRSLVGMMLESHLFEGCQPLSESLRYGVSITDACLGFDSTRQLLLDAAHRMRKQTSA
CHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNSSVSALPLSTLNPANEALTLRLPSSLQLKQQLPLSNALNQQVVAHRQAVRAILDGHDP
CCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCC
RLLVIVGPCSIHDPESALEYASKLSHLAEEVRDDMLLVMRAYVEKPRTTVGWKGLAYDPH
EEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
LDGSDDMAAGLTLSRELMLEMIRVGLPIATELLQPMAAGYFDDLLSWVAIGARTTESQIH
CCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
REMASGLSMPVGFKNGTDGGVTVAVDAMRSAAHPHRHFGVDSQGHPAIIQTPGNQDTHLV
HHHHCCCCCCCCCCCCCCCCEEEEHHHHHHHCCCHHHCCCCCCCCCEEEECCCCCCCEEE
LRGGHQGPNYDRESVSRINAELNRLKIPKRMMVDCSHANSGKDPLRQPGVFNDVLEQRLK
EECCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHC
GDRSLVGMMLESHLFEGCQPLSESLRYGVSITDACLGFDSTRQLLLDAAHRMRKQTSA
CHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6146618; 6396419; 9205837; 9278503; 1977738; 6104668; 2857723; 9056491 [H]