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The map label for this gene is ahpC [H]

Identifier: 77459150

GI number: 77459150

Start: 3370854

End: 3371417

Strand: Reverse

Name: ahpC [H]

Synonym: Pfl01_2925

Alternate gene names: 77459150

Gene position: 3371417-3370854 (Counterclockwise)

Preceding gene: 77459151

Following gene: 77459149

Centisome position: 52.36

GC content: 56.21

Gene sequence:

>564_bases
ATGCCTATCATCAACAGCCAAGTAAAACCGTTCAAAGCTACCGCGTTCAAAAACGGCGACTTCGTACAAGTCTCGGACGC
TGACCTGAAAGGCAAATGGTCCGTAGTGTTTTTCTACCCGGCCGACTTCACTTTCGTTTGCCCAACCGAACTCGAAGACC
TGGCTGACAACTACGCCGCCTTCCAGAAACTGGGCGTAGAGATCTACAGCGTTTCGACCGACACCCACTTTGCTCACGCT
GCCTGGCACAACACTTCGCCAGCCATCGGCAAAATCCAGTACACCATGATCGGCGACCCGACTCAGGTCATCTCCCGCAA
CTTCGACGTGCTGATCGAAGAAGCTGGCCTGGCTGACCGTGGCACCTTCGTGATCAACCCTGAAGGCCAGATCAAAATCG
TTGAACTGAACGATGGCGGCGTTGGCCGTGACGCATCCGAGCTGCTGCGCAAAATCAAGGCTGCTCAGTACGTCGCTGCC
CACCCAGGCGAAGTTTGCCCGGCCAAATGGAAAGAAGGCGAGGCCACGCTGGCTCCGTCCCTGGACCTGGTCGGCAAGAT
CTAA

Upstream 100 bases:

>100_bases
CGAAAACAAATCAGCAGCATCAGGTTTGCCAATGAGCCATCCGTCGAGTGACTGGGTAGGATTCACTCATCGAATTCACA
ACCCTGACGGAGAGTCATCA

Downstream 100 bases:

>100_bases
GTCTGTGACACACGCAATACAGGGCGGGACTCCGCACCTACTCAAGTAAGCTGCACCGCCCAATAGAAAAGCCCGGGCGA
GATTCGCTCGGGCTTTTTTT

Product: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen

Products: NA

Alternate protein names: Alkyl hydroperoxide reductase protein C22; Peroxiredoxin; SCRP-23; Sulfate starvation-induced protein 8; SSI8; Thioredoxin peroxidase [H]

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MPIINSQVKPFKATAFKNGDFVQVSDADLKGKWSVVFFYPADFTFVCPTELEDLADNYAAFQKLGVEIYSVSTDTHFAHA
AWHNTSPAIGKIQYTMIGDPTQVISRNFDVLIEEAGLADRGTFVINPEGQIKIVELNDGGVGRDASELLRKIKAAQYVAA
HPGEVCPAKWKEGEATLAPSLDLVGKI

Sequences:

>Translated_187_residues
MPIINSQVKPFKATAFKNGDFVQVSDADLKGKWSVVFFYPADFTFVCPTELEDLADNYAAFQKLGVEIYSVSTDTHFAHA
AWHNTSPAIGKIQYTMIGDPTQVISRNFDVLIEEAGLADRGTFVINPEGQIKIVELNDGGVGRDASELLRKIKAAQYVAA
HPGEVCPAKWKEGEATLAPSLDLVGKI
>Mature_186_residues
PIINSQVKPFKATAFKNGDFVQVSDADLKGKWSVVFFYPADFTFVCPTELEDLADNYAAFQKLGVEIYSVSTDTHFAHAA
WHNTSPAIGKIQYTMIGDPTQVISRNFDVLIEEAGLADRGTFVINPEGQIKIVELNDGGVGRDASELLRKIKAAQYVAAH
PGEVCPAKWKEGEATLAPSLDLVGKI

Specific function: Directly reduces organic hydroperoxides in its reduced dithiol form [H]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI32483377, Length=179, Percent_Identity=47.4860335195531, Blast_Score=168, Evalue=3e-42,
Organism=Homo sapiens, GI5802974, Length=182, Percent_Identity=46.1538461538462, Blast_Score=167, Evalue=5e-42,
Organism=Homo sapiens, GI32189392, Length=175, Percent_Identity=44, Blast_Score=153, Evalue=1e-37,
Organism=Homo sapiens, GI4505591, Length=175, Percent_Identity=41.7142857142857, Blast_Score=147, Evalue=6e-36,
Organism=Homo sapiens, GI32455266, Length=175, Percent_Identity=41.7142857142857, Blast_Score=147, Evalue=6e-36,
Organism=Homo sapiens, GI32455264, Length=175, Percent_Identity=41.7142857142857, Blast_Score=147, Evalue=6e-36,
Organism=Homo sapiens, GI5453549, Length=180, Percent_Identity=40.5555555555556, Blast_Score=143, Evalue=9e-35,
Organism=Homo sapiens, GI33188454, Length=77, Percent_Identity=50.6493506493506, Blast_Score=87, Evalue=9e-18,
Organism=Homo sapiens, GI4758638, Length=161, Percent_Identity=27.9503105590062, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1786822, Length=187, Percent_Identity=67.9144385026738, Blast_Score=287, Evalue=2e-79,
Organism=Caenorhabditis elegans, GI17554494, Length=179, Percent_Identity=44.6927374301676, Blast_Score=158, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI32565831, Length=174, Percent_Identity=41.9540229885057, Blast_Score=146, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI193204376, Length=174, Percent_Identity=41.9540229885057, Blast_Score=146, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI25153706, Length=164, Percent_Identity=27.4390243902439, Blast_Score=66, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6320661, Length=181, Percent_Identity=35.9116022099448, Blast_Score=128, Evalue=6e-31,
Organism=Saccharomyces cerevisiae, GI6323613, Length=182, Percent_Identity=37.3626373626374, Blast_Score=127, Evalue=8e-31,
Organism=Saccharomyces cerevisiae, GI6319407, Length=162, Percent_Identity=30.2469135802469, Blast_Score=75, Evalue=7e-15,
Organism=Drosophila melanogaster, GI17738015, Length=177, Percent_Identity=41.2429378531073, Blast_Score=152, Evalue=2e-37,
Organism=Drosophila melanogaster, GI21357347, Length=182, Percent_Identity=39.5604395604396, Blast_Score=148, Evalue=2e-36,
Organism=Drosophila melanogaster, GI17157991, Length=180, Percent_Identity=40, Blast_Score=147, Evalue=5e-36,
Organism=Drosophila melanogaster, GI24641739, Length=180, Percent_Identity=40, Blast_Score=147, Evalue=5e-36,
Organism=Drosophila melanogaster, GI24656348, Length=181, Percent_Identity=39.7790055248619, Blast_Score=147, Evalue=5e-36,
Organism=Drosophila melanogaster, GI17864676, Length=181, Percent_Identity=39.7790055248619, Blast_Score=147, Evalue=5e-36,
Organism=Drosophila melanogaster, GI24581278, Length=154, Percent_Identity=31.1688311688312, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17975518, Length=158, Percent_Identity=29.1139240506329, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24652436, Length=158, Percent_Identity=29.1139240506329, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24652434, Length=158, Percent_Identity=29.1139240506329, Blast_Score=74, Evalue=7e-14,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017559
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 20404; Mature: 20273

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIINSQVKPFKATAFKNGDFVQVSDADLKGKWSVVFFYPADFTFVCPTELEDLADNYAA
CCCCCCCCCCEEEEEECCCCEEEEECCCCCCEEEEEEEECCCEEEECCCCHHHHHHHHHH
FQKLGVEIYSVSTDTHFAHAAWHNTSPAIGKIQYTMIGDPTQVISRNFDVLIEEAGLADR
HHHHCEEEEEEECCCCEEEEEECCCCCCCCEEEEEEECCHHHHHHCCCEEEEECCCCCCC
GTFVINPEGQIKIVELNDGGVGRDASELLRKIKAAQYVAAHPGEVCPAKWKEGEATLAPS
CEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHEECCCCCCCCCCCCCCCEEECCC
LDLVGKI
CCEECCC
>Mature Secondary Structure 
PIINSQVKPFKATAFKNGDFVQVSDADLKGKWSVVFFYPADFTFVCPTELEDLADNYAA
CCCCCCCCCEEEEEECCCCEEEEECCCCCCEEEEEEEECCCEEEECCCCHHHHHHHHHH
FQKLGVEIYSVSTDTHFAHAAWHNTSPAIGKIQYTMIGDPTQVISRNFDVLIEEAGLADR
HHHHCEEEEEEECCCCEEEEEECCCCCCCCEEEEEEECCHHHHHHCCCEEEEECCCCCCC
GTFVINPEGQIKIVELNDGGVGRDASELLRKIKAAQYVAAHPGEVCPAKWKEGEATLAPS
CEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHEECCCCCCCCCCCCCCCEEECCC
LDLVGKI
CCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]