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The map label for this gene is kdgR [H]

Identifier: 77459125

GI number: 77459125

Start: 3344115

End: 3345140

Strand: Direct

Name: kdgR [H]

Synonym: Pfl01_2900

Alternate gene names: 77459125

Gene position: 3344115-3345140 (Clockwise)

Preceding gene: 77459121

Following gene: 77459126

Centisome position: 51.94

GC content: 60.62

Gene sequence:

>1026_bases
ATGAACGACTTCTCCGCCGCCCAGCGCAGCCGCGTCACCATGCTCGACGTCGCCGAACACGCCGGTGTGTCCAAGGCCAG
CGTCTCGCGCTTTATCGGCGATGACCGCGCCCTGCTCTCCGATGCCATTGCCCAGCGCATCGAGCAGGCGATTGCCGAAC
TCGGCTATCGCCCCAATCAAATGGCTCGAGGCCTGAAACGCGGACGCACCCGACTGATCGGCATGCTGGTGGCCGATATC
CGCAACCCTTATTCGATTGCCGTGATGCACGGGGTGGAAACCGCCTGCCGCCGACATGGCTACAGCCTGGTGGTGTGCAA
CACCGACCGCGATGACGAGCAGGAACGCCAGCACCTGGCGCTGTTGCGCTCGTACAACATCGAAGGGCTGATCGTGAACA
CCTTGGGCCACCACCGGGATGAACTGGATGAGCTGAAGCGGGAAATGCCACTGGTGCTGGTGGATCGCAAGGTCGATGGG
CTGGACAGCGACATGGTCGGTTTGAACAACCCGCGAGCCATCGAGCTGGCGATGGAACATCTTGAGCAACGCGGCTATCG
CGATGTGCTGTTGGTGACGGAACCTTATGACGGCACCAGTTCGCGGATCGAGCGGGTCAGCAGTTTTCAGCAGCAGGTTG
GCCAGCGCAAAAGCATGAATGGTGCGATGCTGGAAACCGGCCCAAGCCTTGCGAACGATCTTCAAACCTTTTTAGACACA
CCTGATTCGGGCCCTAAAGCCCTGTTCTGCGCCAATGGCGTGGCGGCGCTGGCTTGCACCCGGGCCCTGCGCGAGATCGG
CTGCCGGTTGTTTGAGGATGTCGGGATGATCGCGCTGGATGATCTGGATTGGTATCCGTTGGTAGGTAGCGGGATCACCG
CCCTCGCTCAGCCTACAAAGGAGATTGGGGCGCGGGCGTTTGAGTGTTTGCTCAAGCGGTTGCGTGGGGATGATGAAGTC
GCGCGAACTCTGGATTTTGCACCGATGCTGATCGAGCGCGGCTCAACGCTCAGCAAGGCGGAATAA

Upstream 100 bases:

>100_bases
TCGGTTTTCTTTGTGGGGAAGCGGTTTTTCTGGCTTGACGAGGAGCCGAGAAACGGGTCTCCTGAAACCGGTTTCATGAC
ATAAAAACAAGGTTCACCCT

Downstream 100 bases:

>100_bases
GGCCCTACGGGGCCACCAAAAAATTTTTGAACAAAAATGAAACCGGTTTCAGAGGTAGATAACAATGAATAGACCTGCCG
TTTCCATCAGCCTGTCCAGC

Product: LacI family transcription regulator

Products: NA

Alternate protein names: Kdg operon repressor [H]

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MNDFSAAQRSRVTMLDVAEHAGVSKASVSRFIGDDRALLSDAIAQRIEQAIAELGYRPNQMARGLKRGRTRLIGMLVADI
RNPYSIAVMHGVETACRRHGYSLVVCNTDRDDEQERQHLALLRSYNIEGLIVNTLGHHRDELDELKREMPLVLVDRKVDG
LDSDMVGLNNPRAIELAMEHLEQRGYRDVLLVTEPYDGTSSRIERVSSFQQQVGQRKSMNGAMLETGPSLANDLQTFLDT
PDSGPKALFCANGVAALACTRALREIGCRLFEDVGMIALDDLDWYPLVGSGITALAQPTKEIGARAFECLLKRLRGDDEV
ARTLDFAPMLIERGSTLSKAE

Sequences:

>Translated_341_residues
MNDFSAAQRSRVTMLDVAEHAGVSKASVSRFIGDDRALLSDAIAQRIEQAIAELGYRPNQMARGLKRGRTRLIGMLVADI
RNPYSIAVMHGVETACRRHGYSLVVCNTDRDDEQERQHLALLRSYNIEGLIVNTLGHHRDELDELKREMPLVLVDRKVDG
LDSDMVGLNNPRAIELAMEHLEQRGYRDVLLVTEPYDGTSSRIERVSSFQQQVGQRKSMNGAMLETGPSLANDLQTFLDT
PDSGPKALFCANGVAALACTRALREIGCRLFEDVGMIALDDLDWYPLVGSGITALAQPTKEIGARAFECLLKRLRGDDEV
ARTLDFAPMLIERGSTLSKAE
>Mature_341_residues
MNDFSAAQRSRVTMLDVAEHAGVSKASVSRFIGDDRALLSDAIAQRIEQAIAELGYRPNQMARGLKRGRTRLIGMLVADI
RNPYSIAVMHGVETACRRHGYSLVVCNTDRDDEQERQHLALLRSYNIEGLIVNTLGHHRDELDELKREMPLVLVDRKVDG
LDSDMVGLNNPRAIELAMEHLEQRGYRDVLLVTEPYDGTSSRIERVSSFQQQVGQRKSMNGAMLETGPSLANDLQTFLDT
PDSGPKALFCANGVAALACTRALREIGCRLFEDVGMIALDDLDWYPLVGSGITALAQPTKEIGARAFECLLKRLRGDDEV
ARTLDFAPMLIERGSTLSKAE

Specific function: Transcriptional repressor of the kdg operon for pectin utilization [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=334, Percent_Identity=30.8383233532934, Blast_Score=157, Evalue=7e-40,
Organism=Escherichia coli, GI1787948, Length=338, Percent_Identity=28.1065088757396, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1790369, Length=343, Percent_Identity=28.2798833819242, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI48994940, Length=339, Percent_Identity=25.6637168141593, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1789068, Length=340, Percent_Identity=26.1764705882353, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790715, Length=336, Percent_Identity=24.4047619047619, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1788474, Length=341, Percent_Identity=24.633431085044, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786540, Length=336, Percent_Identity=25, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1789202, Length=288, Percent_Identity=26.3888888888889, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1787906, Length=208, Percent_Identity=28.8461538461538, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1786268, Length=318, Percent_Identity=24.8427672955975, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787580, Length=329, Percent_Identity=22.1884498480243, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789456, Length=341, Percent_Identity=23.1671554252199, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790689, Length=257, Percent_Identity=21.4007782101167, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012310
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37770; Mature: 37770

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDFSAAQRSRVTMLDVAEHAGVSKASVSRFIGDDRALLSDAIAQRIEQAIAELGYRPNQ
CCCHHHHHHCCCHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHH
MARGLKRGRTRLIGMLVADIRNPYSIAVMHGVETACRRHGYSLVVCNTDRDDEQERQHLA
HHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHH
LLRSYNIEGLIVNTLGHHRDELDELKREMPLVLVDRKVDGLDSDMVGLNNPRAIELAMEH
HHHHCCCCEEEEHHHCCCHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHH
LEQRGYRDVLLVTEPYDGTSSRIERVSSFQQQVGQRKSMNGAMLETGPSLANDLQTFLDT
HHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHCC
PDSGPKALFCANGVAALACTRALREIGCRLFEDVGMIALDDLDWYPLVGSGITALAQPTK
CCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCHHHHHCCHH
EIGARAFECLLKRLRGDDEVARTLDFAPMLIERGSTLSKAE
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MNDFSAAQRSRVTMLDVAEHAGVSKASVSRFIGDDRALLSDAIAQRIEQAIAELGYRPNQ
CCCHHHHHHCCCHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHH
MARGLKRGRTRLIGMLVADIRNPYSIAVMHGVETACRRHGYSLVVCNTDRDDEQERQHLA
HHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHH
LLRSYNIEGLIVNTLGHHRDELDELKREMPLVLVDRKVDGLDSDMVGLNNPRAIELAMEH
HHHHCCCCEEEEHHHCCCHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHH
LEQRGYRDVLLVTEPYDGTSSRIERVSSFQQQVGQRKSMNGAMLETGPSLANDLQTFLDT
HHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHCC
PDSGPKALFCANGVAALACTRALREIGCRLFEDVGMIALDDLDWYPLVGSGITALAQPTK
CCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCHHHHHCCHH
EIGARAFECLLKRLRGDDEVARTLDFAPMLIERGSTLSKAE
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]