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The map label for this gene is galE [H]

Identifier: 77459049

GI number: 77459049

Start: 3255899

End: 3256954

Strand: Direct

Name: galE [H]

Synonym: Pfl01_2824

Alternate gene names: 77459049

Gene position: 3255899-3256954 (Clockwise)

Preceding gene: 77459048

Following gene: 77459050

Centisome position: 50.57

GC content: 59.66

Gene sequence:

>1056_bases
ATGCGCAAAACCACGTTGATTACTGGCGGAGCCGGCTACATCGGCTCGCATACGGCTCTGGCCCTCATTAACGCCGGCCA
CAAGGTGCTGGTGCTCGACAACCTGTGCAACAGCTGTCGAGAGTGCATCCGGCGCCTCGAGCAACTGACCCTGACCCGCG
TCGACTTCATCAAGGGCGATATTCGCGATCCGGTCCTGCTCGACGATATCTTCAGCCGGTACGACATCGAGGCCGTGGTG
CACTTTGCCAGTCTCAAATCCGTCGAAGAAAGCGTGCGCAAGCCGCTGGACTACTACGCCAACAATGTTGCCGGTACGCT
CGACCTGTGCCAGGCAATGGCCCGCAACAACGTTTTCCAACTGGTGTTCAGCTCATCGGCCACGGTGTACGGAGAACCGG
CAAATACGCCGATTGCCGAGGATTTCGGCACCGGCAAACCGGTCAACCCCTATGGCCGCACCAAGCTCATGATCGAAGAG
TTGCTGACGGATCTGTGCAACTCCGATCCGCGCTGGAGCATTGGATTATTGCGTTACTTCAACCCGATCGGCGCCCACGA
AAGCGGAATGATCGGCGAAGACCCGAGCGGCCGACCCAACAACCTGTTGCCTTGCCTGACCCAGGTTGCCATAGGCCGGA
TACCCGAACTCACGGTGTACGGCAGCGACTATCCCACCGTGGACGGGACCTGCGTGCGCGACTACATCCACGTGGTCGAC
CTGGCCATCGGTCATCTCAAGGCACTGCAAGTGCTACAGCACGACAATGGCATTCATTTCTGGAACCTCGGCACGGGCGT
CGGCTACAGCGTGCTACAGATCATCCACAGTTTCGAGGACATCACCGGCATCAGCATTCCGTACCGCTTCGCCCCTCGAC
GTCTCGGCGACATCGCCAAGTGCTGGGCCGATCCGGCCAAGGCAGGACGCGAACTGGGCTGGAGCGCGCAGCGCGGCCTG
GAACAAATGATCACCGATAGCTGGCGCTGGCAGTCGTGCAATCCGCAGGGGTATCAATCTTCATTCAAGATTCCGGCACC
CGTTGCGGTGAAGTGA

Upstream 100 bases:

>100_bases
ATGCCGTGGGTTACAGCGCCCTGCACCCGCACTGGCCACAGGAATTCAAATCGGTTTTCACCTCCCGCTGAGTTCAGCCC
TGAGACAGGAAGGCCTCACC

Downstream 100 bases:

>100_bases
TGCCGATGTTCAGAGAATGTCTGCTGGCCGTGCTGTTTTCGGTTGCGCTGCCAAGCAACGCAGCGCAGGCGCCTCCTGCG
GTGCCGACCACCGGCCTGGT

Product: UDP-galactose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MRKTTLITGGAGYIGSHTALALINAGHKVLVLDNLCNSCRECIRRLEQLTLTRVDFIKGDIRDPVLLDDIFSRYDIEAVV
HFASLKSVEESVRKPLDYYANNVAGTLDLCQAMARNNVFQLVFSSSATVYGEPANTPIAEDFGTGKPVNPYGRTKLMIEE
LLTDLCNSDPRWSIGLLRYFNPIGAHESGMIGEDPSGRPNNLLPCLTQVAIGRIPELTVYGSDYPTVDGTCVRDYIHVVD
LAIGHLKALQVLQHDNGIHFWNLGTGVGYSVLQIIHSFEDITGISIPYRFAPRRLGDIAKCWADPAKAGRELGWSAQRGL
EQMITDSWRWQSCNPQGYQSSFKIPAPVAVK

Sequences:

>Translated_351_residues
MRKTTLITGGAGYIGSHTALALINAGHKVLVLDNLCNSCRECIRRLEQLTLTRVDFIKGDIRDPVLLDDIFSRYDIEAVV
HFASLKSVEESVRKPLDYYANNVAGTLDLCQAMARNNVFQLVFSSSATVYGEPANTPIAEDFGTGKPVNPYGRTKLMIEE
LLTDLCNSDPRWSIGLLRYFNPIGAHESGMIGEDPSGRPNNLLPCLTQVAIGRIPELTVYGSDYPTVDGTCVRDYIHVVD
LAIGHLKALQVLQHDNGIHFWNLGTGVGYSVLQIIHSFEDITGISIPYRFAPRRLGDIAKCWADPAKAGRELGWSAQRGL
EQMITDSWRWQSCNPQGYQSSFKIPAPVAVK
>Mature_351_residues
MRKTTLITGGAGYIGSHTALALINAGHKVLVLDNLCNSCRECIRRLEQLTLTRVDFIKGDIRDPVLLDDIFSRYDIEAVV
HFASLKSVEESVRKPLDYYANNVAGTLDLCQAMARNNVFQLVFSSSATVYGEPANTPIAEDFGTGKPVNPYGRTKLMIEE
LLTDLCNSDPRWSIGLLRYFNPIGAHESGMIGEDPSGRPNNLLPCLTQVAIGRIPELTVYGSDYPTVDGTCVRDYIHVVD
LAIGHLKALQVLQHDNGIHFWNLGTGVGYSVLQIIHSFEDITGISIPYRFAPRRLGDIAKCWADPAKAGRELGWSAQRGL
EQMITDSWRWQSCNPQGYQSSFKIPAPVAVK

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=344, Percent_Identity=53.1976744186046, Blast_Score=373, Evalue=1e-103,
Organism=Homo sapiens, GI56118217, Length=344, Percent_Identity=53.1976744186046, Blast_Score=373, Evalue=1e-103,
Organism=Homo sapiens, GI189083684, Length=344, Percent_Identity=53.1976744186046, Blast_Score=373, Evalue=1e-103,
Organism=Homo sapiens, GI42516563, Length=356, Percent_Identity=25.561797752809, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI7657641, Length=277, Percent_Identity=25.9927797833935, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1786974, Length=333, Percent_Identity=54.3543543543543, Blast_Score=386, Evalue=1e-108,
Organism=Escherichia coli, GI48994969, Length=365, Percent_Identity=24.1095890410959, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1788353, Length=362, Percent_Identity=26.5193370165746, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71982035, Length=344, Percent_Identity=49.1279069767442, Blast_Score=353, Evalue=9e-98,
Organism=Caenorhabditis elegans, GI71982038, Length=346, Percent_Identity=48.8439306358381, Blast_Score=351, Evalue=4e-97,
Organism=Caenorhabditis elegans, GI17539532, Length=321, Percent_Identity=23.98753894081, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319493, Length=346, Percent_Identity=49.7109826589595, Blast_Score=334, Evalue=2e-92,
Organism=Drosophila melanogaster, GI19923002, Length=343, Percent_Identity=54.2274052478134, Blast_Score=394, Evalue=1e-110,
Organism=Drosophila melanogaster, GI21356223, Length=324, Percent_Identity=25.3086419753086, Blast_Score=79, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040
- InterPro:   IPR008089 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 38797; Mature: 38797

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKTTLITGGAGYIGSHTALALINAGHKVLVLDNLCNSCRECIRRLEQLTLTRVDFIKGD
CCCEEEEECCCCCCCCHHHEEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IRDPVLLDDIFSRYDIEAVVHFASLKSVEESVRKPLDYYANNVAGTLDLCQAMARNNVFQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEE
LVFSSSATVYGEPANTPIAEDFGTGKPVNPYGRTKLMIEELLTDLCNSDPRWSIGLLRYF
EEECCCCEEECCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEHHHHHH
NPIGAHESGMIGEDPSGRPNNLLPCLTQVAIGRIPELTVYGSDYPTVDGTCVRDYIHVVD
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHH
LAIGHLKALQVLQHDNGIHFWNLGTGVGYSVLQIIHSFEDITGISIPYRFAPRRLGDIAK
HHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHH
CWADPAKAGRELGWSAQRGLEQMITDSWRWQSCNPQGYQSSFKIPAPVAVK
HHCCHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRKTTLITGGAGYIGSHTALALINAGHKVLVLDNLCNSCRECIRRLEQLTLTRVDFIKGD
CCCEEEEECCCCCCCCHHHEEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IRDPVLLDDIFSRYDIEAVVHFASLKSVEESVRKPLDYYANNVAGTLDLCQAMARNNVFQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEE
LVFSSSATVYGEPANTPIAEDFGTGKPVNPYGRTKLMIEELLTDLCNSDPRWSIGLLRYF
EEECCCCEEECCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEHHHHHH
NPIGAHESGMIGEDPSGRPNNLLPCLTQVAIGRIPELTVYGSDYPTVDGTCVRDYIHVVD
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHH
LAIGHLKALQVLQHDNGIHFWNLGTGVGYSVLQIIHSFEDITGISIPYRFAPRRLGDIAK
HHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHH
CWADPAKAGRELGWSAQRGLEQMITDSWRWQSCNPQGYQSSFKIPAPVAVK
HHCCHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8978088; 8969509; 9384377 [H]