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The map label for this gene is eco

Identifier: 77458845

GI number: 77458845

Start: 2998958

End: 2999443

Strand: Reverse

Name: eco

Synonym: Pfl01_2620

Alternate gene names: 77458845

Gene position: 2999443-2998958 (Counterclockwise)

Preceding gene: 77458847

Following gene: 77458841

Centisome position: 46.59

GC content: 61.32

Gene sequence:

>486_bases
ATGGGAAATTTCACCGTCCGCGCGACGGCCGGCCTGATGCTCGCCAGCCTGTCCACCCTCGCCCACGCCGCCAAGCTTGA
AGACACCGCGCCTTATCCGAAGGCCGAAGCGGGCTTCACGCGCCAGGTCATCCACCTGCCGCAACAGGCCCAGGAAGAAA
ACTTCAAAGTCGAAATCCTCGCCGGCAAAACCCTCGAAGTCGATTGCAACCGCCAGCGTCTGGGCGGCACCCTCGAAGAG
AAAAACCTCGAAGGCTGGGGCTATCCGTTCTACCGCCTGGAAAAAGTCAGCGGCCCGATGAGCACGCTGATGGCCTGCCC
GCCCGGCACCCAGAAAAAACGCGTATTCGTGCCGGTGATCGGTGACGGTTTCACCGTGCGCTACAACAGCAAGCTGCCGA
TCGTGGTTTACGCACCGCAGGACGTTGAAGTGCGTTTCCGCATCTGGTCGGCCTCGGACAAGATTGGCGTGGCCATTCCC
GAGTAA

Upstream 100 bases:

>100_bases
CGTGCAGGCACTGCAATTTGCAAGCGGCTGGCGGTTTGCATTCATCGCCTGCGACAGTGAGAATGCCCGTCAACCAACGT
ACACCCGCCAGGAGGCTTCA

Downstream 100 bases:

>100_bases
CTTCAAGCCACAACGCCGCACGCCGCCGCTCGCTCGGCGACGTGTCGCAAGCTGTCGAAATTGATATTGGCGCCAGAATC
GATGGCGATCAGCGTCTGAC

Product: ecotin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MGNFTVRATAGLMLASLSTLAHAAKLEDTAPYPKAEAGFTRQVIHLPQQAQEENFKVEILAGKTLEVDCNRQRLGGTLEE
KNLEGWGYPFYRLEKVSGPMSTLMACPPGTQKKRVFVPVIGDGFTVRYNSKLPIVVYAPQDVEVRFRIWSASDKIGVAIP
E

Sequences:

>Translated_161_residues
MGNFTVRATAGLMLASLSTLAHAAKLEDTAPYPKAEAGFTRQVIHLPQQAQEENFKVEILAGKTLEVDCNRQRLGGTLEE
KNLEGWGYPFYRLEKVSGPMSTLMACPPGTQKKRVFVPVIGDGFTVRYNSKLPIVVYAPQDVEVRFRIWSASDKIGVAIP
E
>Mature_160_residues
GNFTVRATAGLMLASLSTLAHAAKLEDTAPYPKAEAGFTRQVIHLPQQAQEENFKVEILAGKTLEVDCNRQRLGGTLEEK
NLEGWGYPFYRLEKVSGPMSTLMACPPGTQKKRVFVPVIGDGFTVRYNSKLPIVVYAPQDVEVRFRIWSASDKIGVAIPE

Specific function: General inhibitor of family S1 serine proteases

COG id: COG4574

COG function: function code R; Serine protease inhibitor ecotin

Gene ontology:

Cell location: Periplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protease inhibitor I11 (ecotin) family

Homologues:

Organism=Escherichia coli, GI1788538, Length=154, Percent_Identity=53.8961038961039, Blast_Score=170, Evalue=4e-44,

Paralogues:

None

Copy number: 260 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): ECOT_PSEPF (Q3KCZ4)

Other databases:

- EMBL:   CP000094
- RefSeq:   YP_348351.1
- ProteinModelPortal:   Q3KCZ4
- SMR:   Q3KCZ4
- STRING:   Q3KCZ4
- MEROPS:   I11.001
- GeneID:   3714261
- GenomeReviews:   CP000094_GR
- KEGG:   pfo:Pfl01_2620
- eggNOG:   COG4574
- HOGENOM:   HBG710412
- OMA:   RYDSRLP
- ProtClustDB:   PRK03719
- BioCyc:   PFLU205922:PFL_2620-MONOMER
- HAMAP:   MF_00706
- InterPro:   IPR005658
- InterPro:   IPR023189
- InterPro:   IPR023084
- Gene3D:   G3DSA:2.60.40.550
- PIRSF:   PIRSF006865

Pfam domain/function: PF03974 Ecotin; SSF49772 Prot_inh_ecotin

EC number: NA

Molecular weight: Translated: 17783; Mature: 17652

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNFTVRATAGLMLASLSTLAHAAKLEDTAPYPKAEAGFTRQVIHLPQQAQEENFKVEIL
CCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCCCCCEEEEE
AGKTLEVDCNRQRLGGTLEEKNLEGWGYPFYRLEKVSGPMSTLMACPPGTQKKRVFVPVI
ECCEEEEECCHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHEEECCCCCCCCEEEEEEE
GDGFTVRYNSKLPIVVYAPQDVEVRFRIWSASDKIGVAIPE
CCCEEEEECCCCCEEEECCCCCEEEEEEEECCCCEEEEECC
>Mature Secondary Structure 
GNFTVRATAGLMLASLSTLAHAAKLEDTAPYPKAEAGFTRQVIHLPQQAQEENFKVEIL
CCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCCCCCEEEEE
AGKTLEVDCNRQRLGGTLEEKNLEGWGYPFYRLEKVSGPMSTLMACPPGTQKKRVFVPVI
ECCEEEEECCHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHEEECCCCCCCCEEEEEEE
GDGFTVRYNSKLPIVVYAPQDVEVRFRIWSASDKIGVAIPE
CCCEEEEECCCCCEEEECCCCCEEEEEEEECCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA