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The map label for this gene is nodT [H]

Identifier: 77458708

GI number: 77458708

Start: 2838208

End: 2839668

Strand: Reverse

Name: nodT [H]

Synonym: Pfl01_2483

Alternate gene names: 77458708

Gene position: 2839668-2838208 (Counterclockwise)

Preceding gene: 77458711

Following gene: 77458704

Centisome position: 44.11

GC content: 63.31

Gene sequence:

>1461_bases
ATGCCCCCCCTCCGCCCGATTGCTCTTTTGGTTACCGCCGGCTTGATGTCAGGTTGCGCGGTAGGCCCGGATTACCATCG
TCCGGACGCCCCGATTTCGGACCATTACGTCGGCCAGTCCGCTGTCGAACCGCGGTCCGAATCGACGCCGGATAATCTTG
TCGCCTGGTGGAAAAACTTTAATGATCCACTGCTGACCGACTTCATCAACCAGGCGCTGCAGCAGAATCTGGACCTGGCG
CAGGCGTCAGCGCGCGTCACCCAGGCCAGGGCCGGCCTGGGCGCCGCCAATGCAGCACTGCTGCCCTCGGCGAGCATCAG
CGCACAGGCTGCACGCGCTTATCAGTCCGTCGAGACACCACTGGGCCAGGTGTTGAATTCAACACCCGGCTACGACCGTT
ACGGCAATGCCTACGAGGCCAACCTTGAGGCAGGCTGGGAAGTAGATGTATTTGGCGGACTGCGCCGCGGACGCGAGGCG
GCACTGGCCGAGTACCAGTCCTCGGCAGCGGGTTTCACCGCTACAAGGTTGGCGATCGCTGCGCAAACGGCCGATATCTA
CATCACCCTGCGCGGATTACAGGCACGGCTGGAGATTGCCAACCGGCAAGTCGAAACCCGGCGCGCGTTGCTGGAAAAGG
TCCGGCTGCTTTACGGCAAGGGTCTGGCCGCGGAGTATCAGGTGCGCCAGGCCGAGGGTGAGTTGTCGCAAGTCCAGGCG
ACCGTTCCGGTACTGCAAAGCGGTCTGGAGGCGGCCATGAATGCGATGGACGTGCTGCTCGGCACGCCTCCCGGCACTCA
CCGCACGCAACTGGCACGTGAGGGCGAGATTCCCGATGTGCCGTCGCTGAATAGGCTGGGCACTCCGGCAGATCTGCTGC
GGCGCAGACCGGACCTGATCGTCGCCGAACGCCGCCTTGCGGCCTCCAACGCGCGTATCGGTGAAGCGATTGCCGAGTAC
TACCCGAAATTTTCCCTCAGCGCCTTGCTCGGCAGCGCGACAGCCGTCTCCGGCGGCAATCTTTTCACCAGTGGCGCAAG
CCAGTCGGCCGGTGTCTTGGGTTTGCGCTGGCGGCTATTCGACTTCGCACGCATCAACGCCCGGATCGATCAGGCCAAAG
GCCAGGAATCTGAAGCATTGGCCGCGTATCGCCAGTCAGTACTGCGCGCCACCGAAGATGTAGAGAACGCGCTGTCCTCA
CTGGTGAATCGGCAAACTCAGACCACCACCCTTACCGGCGGCGAAGAGGCGCTGACTCAAGCTCGCCAGTCCTCGTTCAC
CGCCTATGAAAAAGGCACCGCCAGCCTGATCGATGTCCTGCACGCCGACGAAACACTGTTGCAGGCCTCCGACGCCAGAG
CGCAAGCGCGGACCGAATCGGCCCGTGCGGCGGTGGCGGTATTCAAGTCGCTCGGTGGAGGATGGCAACCCGTTGAGCCG
GGTTCTGTAGCGGCGCGCTGA

Upstream 100 bases:

>100_bases
CTACCCACCTCTGAAAGCTGCCAAACTTCACGAGCGTCGCTAATTGACAGATTGTGACCAAAACATATTATGGTCACAAA
CAGCCCGCCAAGGAACTCAC

Downstream 100 bases:

>100_bases
GCAGCAACCTCAGATCGCTTCAAGAGTCGGGAGACACGTGTACTCCCGACCCGCATTTGGCTTGATGGCGCTCAACTAGA
AGCGATAACTGACCGACGTA

Product: RND efflux system outer membrane lipoprotein NodT

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 486; Mature: 485

Protein sequence:

>486_residues
MPPLRPIALLVTAGLMSGCAVGPDYHRPDAPISDHYVGQSAVEPRSESTPDNLVAWWKNFNDPLLTDFINQALQQNLDLA
QASARVTQARAGLGAANAALLPSASISAQAARAYQSVETPLGQVLNSTPGYDRYGNAYEANLEAGWEVDVFGGLRRGREA
ALAEYQSSAAGFTATRLAIAAQTADIYITLRGLQARLEIANRQVETRRALLEKVRLLYGKGLAAEYQVRQAEGELSQVQA
TVPVLQSGLEAAMNAMDVLLGTPPGTHRTQLAREGEIPDVPSLNRLGTPADLLRRRPDLIVAERRLAASNARIGEAIAEY
YPKFSLSALLGSATAVSGGNLFTSGASQSAGVLGLRWRLFDFARINARIDQAKGQESEALAAYRQSVLRATEDVENALSS
LVNRQTQTTTLTGGEEALTQARQSSFTAYEKGTASLIDVLHADETLLQASDARAQARTESARAAVAVFKSLGGGWQPVEP
GSVAAR

Sequences:

>Translated_486_residues
MPPLRPIALLVTAGLMSGCAVGPDYHRPDAPISDHYVGQSAVEPRSESTPDNLVAWWKNFNDPLLTDFINQALQQNLDLA
QASARVTQARAGLGAANAALLPSASISAQAARAYQSVETPLGQVLNSTPGYDRYGNAYEANLEAGWEVDVFGGLRRGREA
ALAEYQSSAAGFTATRLAIAAQTADIYITLRGLQARLEIANRQVETRRALLEKVRLLYGKGLAAEYQVRQAEGELSQVQA
TVPVLQSGLEAAMNAMDVLLGTPPGTHRTQLAREGEIPDVPSLNRLGTPADLLRRRPDLIVAERRLAASNARIGEAIAEY
YPKFSLSALLGSATAVSGGNLFTSGASQSAGVLGLRWRLFDFARINARIDQAKGQESEALAAYRQSVLRATEDVENALSS
LVNRQTQTTTLTGGEEALTQARQSSFTAYEKGTASLIDVLHADETLLQASDARAQARTESARAAVAVFKSLGGGWQPVEP
GSVAAR
>Mature_485_residues
PPLRPIALLVTAGLMSGCAVGPDYHRPDAPISDHYVGQSAVEPRSESTPDNLVAWWKNFNDPLLTDFINQALQQNLDLAQ
ASARVTQARAGLGAANAALLPSASISAQAARAYQSVETPLGQVLNSTPGYDRYGNAYEANLEAGWEVDVFGGLRRGREAA
LAEYQSSAAGFTATRLAIAAQTADIYITLRGLQARLEIANRQVETRRALLEKVRLLYGKGLAAEYQVRQAEGELSQVQAT
VPVLQSGLEAAMNAMDVLLGTPPGTHRTQLAREGEIPDVPSLNRLGTPADLLRRRPDLIVAERRLAASNARIGEAIAEYY
PKFSLSALLGSATAVSGGNLFTSGASQSAGVLGLRWRLFDFARINARIDQAKGQESEALAAYRQSVLRATEDVENALSSL
VNRQTQTTTLTGGEEALTQARQSSFTAYEKGTASLIDVLHADETLLQASDARAQARTESARAAVAVFKSLGGGWQPVEPG
SVAAR

Specific function: In Pathogenic Strains It Allows The Bacteria To Invade Brain Microvascular Endothelial Cells (Bmec) Thus Allowing It To Cross The Blood-Brain Barrier And Cause Neonatal Meningitis. [C]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=486, Percent_Identity=24.6913580246914, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI2367348, Length=493, Percent_Identity=23.1237322515213, Blast_Score=89, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 51823; Mature: 51691

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPLRPIALLVTAGLMSGCAVGPDYHRPDAPISDHYVGQSAVEPRSESTPDNLVAWWKNF
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCHHHHHHHHCC
NDPLLTDFINQALQQNLDLAQASARVTQARAGLGAANAALLPSASISAQAARAYQSVETP
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHHHH
LGQVLNSTPGYDRYGNAYEANLEAGWEVDVFGGLRRGREAALAEYQSSAAGFTATRLAIA
HHHHHCCCCCCCCCCCCEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHE
AQTADIYITLRGLQARLEIANRQVETRRALLEKVRLLYGKGLAAEYQVRQAEGELSQVQA
EECCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHH
TVPVLQSGLEAAMNAMDVLLGTPPGTHRTQLAREGEIPDVPSLNRLGTPADLLRRRPDLI
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCHH
VAERRLAASNARIGEAIAEYYPKFSLSALLGSATAVSGGNLFTSGASQSAGVLGLRWRLF
HHHHHHHHCCCHHHHHHHHHCCCHHHHHHHCCHHEECCCCEEECCCCCCCCEEEEHHHHH
DFARINARIDQAKGQESEALAAYRQSVLRATEDVENALSSLVNRQTQTTTLTGGEEALTQ
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHH
ARQSSFTAYEKGTASLIDVLHADETLLQASDARAQARTESARAAVAVFKSLGGGWQPVEP
HHHHCCHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GSVAAR
CCCCCC
>Mature Secondary Structure 
PPLRPIALLVTAGLMSGCAVGPDYHRPDAPISDHYVGQSAVEPRSESTPDNLVAWWKNF
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCHHHHHHHHCC
NDPLLTDFINQALQQNLDLAQASARVTQARAGLGAANAALLPSASISAQAARAYQSVETP
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHHHH
LGQVLNSTPGYDRYGNAYEANLEAGWEVDVFGGLRRGREAALAEYQSSAAGFTATRLAIA
HHHHHCCCCCCCCCCCCEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHE
AQTADIYITLRGLQARLEIANRQVETRRALLEKVRLLYGKGLAAEYQVRQAEGELSQVQA
EECCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHH
TVPVLQSGLEAAMNAMDVLLGTPPGTHRTQLAREGEIPDVPSLNRLGTPADLLRRRPDLI
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCHH
VAERRLAASNARIGEAIAEYYPKFSLSALLGSATAVSGGNLFTSGASQSAGVLGLRWRLF
HHHHHHHHCCCHHHHHHHHHCCCHHHHHHHCCHHEECCCCEEECCCCCCCCEEEEHHHHH
DFARINARIDQAKGQESEALAAYRQSVLRATEDVENALSSLVNRQTQTTTLTGGEEALTQ
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHH
ARQSSFTAYEKGTASLIDVLHADETLLQASDARAQARTESARAAVAVFKSLGGGWQPVEP
HHHHCCHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GSVAAR
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2338917; 2622339 [H]