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The map label for this gene is yjeP [H]

Identifier: 77458619

GI number: 77458619

Start: 2750740

End: 2753124

Strand: Reverse

Name: yjeP [H]

Synonym: Pfl01_2392

Alternate gene names: 77458619

Gene position: 2753124-2750740 (Counterclockwise)

Preceding gene: 77458624

Following gene: 77458613

Centisome position: 42.76

GC content: 63.44

Gene sequence:

>2385_bases
ATGCGTAATGCATTGAAGTCATTGATGTTCATCGCTTTGATCCTGCTCGGCTCGGGGTTCGTGGCGGTGTCGGCCGCCGA
CCTGTCCGGCACAGCGGATGTCAGCACCGGCGCCCCGCTCCCCGGCGTCTCGCAAAGCGATCTGCAAGCCTTGCAACTGC
GCCTCGACGGACTCAAGCAGCAGATCTCGTCCGCCAACAATTACAACCAGCTCGAAGGCCCGCAGGATCGGGTGCAGACG
TTCATTCTGGACATTGATCGACTGTCGGCGTCGCTGTTGCCGCAGCAGGCGCAACTGGCCGTGCAACTGGGCGTACTCGG
TGCCGCGCCGGCCGAAGCGGTCGCTGCCGAACAAGCCGATATCGCGGCGCAGCGGGCGACGTTGATCGAGCAAAAAACCA
AAGTCGATACGGCGTTGAAGAACCTCGCCATCCTCAAGCAAAGCGCCACGGAGCTGATCACCCAGATCGCCGGTATCCGC
CGCACCTTGCTCGAAAGCGAACTGACGCTCAGCACCGACAGCATTCTGAATCCCGGTTTCTGGGCTCCCCTTGTCAATCC
GTCAGCGGACGACCGCCAGCGTCTGCGCTTTTTCGTCGAACAGGTGCAACAGACCGGTGCCGAAGCCTGGCAACCCGGCC
AGCGTTTTTACACCGCCCTGCTGGTGGTGCTGGCCTTCGTCGTCTGGACGCTGGGCCGGCGGCTGGCCGATCGCTGGCTG
GCGTGGGTGTGCATTCACCGCATGCCGGAGGGTCGACTGCGCCGCAGTTCGCTGGCGTTCGCCTCGGCACTGGCGACACT
CGCGACCACCGCCATCGCCCTGCAACTGCTCTATTACGCCTGCACCCGTCACGTGCCGTTGCCGCCGATGCTGGCGACAT
TTTCCGATGAGTTCGGGAAAGTGGTTTATGCCTGCGTGTTGATCACAGGGCTCAGCCGCGCCCTGCTGTCCACCGAGCAT
CCGTCGTGGCGCTTGCCGGCGGTGGCTGACGAGGTGGCAAACGCGCTGCAGCCATTTGCGCGGATCCTCGCCGCCGCGCT
GCTGGTGCTGGTGACGGCGGTGCAGGTCAGCAATGCCTCCGGCATGAGCAGCCAGATCGTGCTCGCAGGCCGAGGCATCA
TTGCGCTGGTGGTGCTGGTCATCGTCACAACGTTGCTGATGCGCGTCGGTAAAGTGCGCAAAGTGTTGGCGGCGGCCGGG
GATACGCAGGTGGCGGGCAACACGTTTGCCGGGGTGATTTACACCGTGGCCACCCTGGCCATGGTGCTGTCGTTCGGCAC
CCTGCTGACGGGGTATGTGTCGCTGGCGCGGTTCATCACCTACGAACTGGTCTGGGCGTTTATCGTGTTTTCCGGGTTTT
ACCTGCTGATGCAGTTGCTCAAGGACAGCTGCGAGTACTTCTTCTCGCCCCGCCACTCCAGCGGCAAGGCGCTGAAACAG
CTGCTCGGCGTGGGTGATCGGCGTCTCGAACAGGCCTCGACCCTGCTGGCCGGTTTCGGTAGGGCTGCGCTGCTGCTGTT
GGCCGTCATCACGCTGTTTGTCGGCGGGATCGGCACCACCCTGGGCCAACTGGCCAACAACATCGGCACGATCCTCGGCG
GCGCCGGCCTGCGCAAACTGAACATCGTCCCCGGCCATTTGCTCAACGCGATGCTGGCGCTGCTGATCGGCATCTACCTG
ATCCGCGCCCTGCGCCGCTGGCTCGACAACGAGTTCCTGCCCAAGACCGACATGGACCCGGGCATGTGCGCCTCACTCAG
CACGCTGTTTTCCAACATCGGTTATGCGGTGGTGATCCTGCTGACCCTGTCATCGCTGGGCGTGCAATGGACCAACCTGG
CGTGGATCGTCAGCGCCCTGTCGGTGGGCATCGGCTTCGGCTTGCAGGAGATCGTGAAGAACTTCGTCTCCGGGCTGATC
CTGCTCACCGAACGGCCGGTCAAGGTCGGCGACCTGATCAGCATCAGCGGCGTCGAGGGCGACATCCGCCGGATCAACGT
GCGCGCCACCGAGATCCAGCTCAGCGATCGCTCGATCGTGATCGTGCCCAACTCGCAACTGATCTCGCAGAACCTGCGTA
ACGTCACCCTCGGCGGCAGCGCCCAAGGCGTGGCGACGCTGGAGCTGATGTTCCCGCTGGACATCGACCCCGAACAGGTG
CAGAACCTGCTGTTCGACACCTACAAGGAACACGAAACCATCCTCGAAAAACCGGCGCCGTTCGTGCGCTTCAGCAAGCT
GACGCCGGACGGGATTACGTTGACGGTGACCGGGTATGTGGCCAGCCCGAGGATTGTCGGGACGACCAAGAGTGATCTGC
TGTTCGAGATACTCAAGCGGCTGGGGGCGGCGGGGATCGAGCTGGCGAAGCCGCCGAGTACCTGA

Upstream 100 bases:

>100_bases
GGACACGCATTAAGCCAGGATTAGCAGCAGAAAATGATGCAGCAGGCGCCCGATCACCTAACCTCAATGCTTGTGTGATC
AACCGGAATCGCCCAGTCCC

Downstream 100 bases:

>100_bases
GGAAAAACCTGATGGGGCCTGTACCGCTGCGCGCCTGCTCGATCAGGCCTCAGGGGTGTCAGTTGACGCTGGAGCCGCTT
CAGCCTCCAGCTTCAAGCGA

Product: mechanosensitive ion channel MscS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 794; Mature: 794

Protein sequence:

>794_residues
MRNALKSLMFIALILLGSGFVAVSAADLSGTADVSTGAPLPGVSQSDLQALQLRLDGLKQQISSANNYNQLEGPQDRVQT
FILDIDRLSASLLPQQAQLAVQLGVLGAAPAEAVAAEQADIAAQRATLIEQKTKVDTALKNLAILKQSATELITQIAGIR
RTLLESELTLSTDSILNPGFWAPLVNPSADDRQRLRFFVEQVQQTGAEAWQPGQRFYTALLVVLAFVVWTLGRRLADRWL
AWVCIHRMPEGRLRRSSLAFASALATLATTAIALQLLYYACTRHVPLPPMLATFSDEFGKVVYACVLITGLSRALLSTEH
PSWRLPAVADEVANALQPFARILAAALLVLVTAVQVSNASGMSSQIVLAGRGIIALVVLVIVTTLLMRVGKVRKVLAAAG
DTQVAGNTFAGVIYTVATLAMVLSFGTLLTGYVSLARFITYELVWAFIVFSGFYLLMQLLKDSCEYFFSPRHSSGKALKQ
LLGVGDRRLEQASTLLAGFGRAALLLLAVITLFVGGIGTTLGQLANNIGTILGGAGLRKLNIVPGHLLNAMLALLIGIYL
IRALRRWLDNEFLPKTDMDPGMCASLSTLFSNIGYAVVILLTLSSLGVQWTNLAWIVSALSVGIGFGLQEIVKNFVSGLI
LLTERPVKVGDLISISGVEGDIRRINVRATEIQLSDRSIVIVPNSQLISQNLRNVTLGGSAQGVATLELMFPLDIDPEQV
QNLLFDTYKEHETILEKPAPFVRFSKLTPDGITLTVTGYVASPRIVGTTKSDLLFEILKRLGAAGIELAKPPST

Sequences:

>Translated_794_residues
MRNALKSLMFIALILLGSGFVAVSAADLSGTADVSTGAPLPGVSQSDLQALQLRLDGLKQQISSANNYNQLEGPQDRVQT
FILDIDRLSASLLPQQAQLAVQLGVLGAAPAEAVAAEQADIAAQRATLIEQKTKVDTALKNLAILKQSATELITQIAGIR
RTLLESELTLSTDSILNPGFWAPLVNPSADDRQRLRFFVEQVQQTGAEAWQPGQRFYTALLVVLAFVVWTLGRRLADRWL
AWVCIHRMPEGRLRRSSLAFASALATLATTAIALQLLYYACTRHVPLPPMLATFSDEFGKVVYACVLITGLSRALLSTEH
PSWRLPAVADEVANALQPFARILAAALLVLVTAVQVSNASGMSSQIVLAGRGIIALVVLVIVTTLLMRVGKVRKVLAAAG
DTQVAGNTFAGVIYTVATLAMVLSFGTLLTGYVSLARFITYELVWAFIVFSGFYLLMQLLKDSCEYFFSPRHSSGKALKQ
LLGVGDRRLEQASTLLAGFGRAALLLLAVITLFVGGIGTTLGQLANNIGTILGGAGLRKLNIVPGHLLNAMLALLIGIYL
IRALRRWLDNEFLPKTDMDPGMCASLSTLFSNIGYAVVILLTLSSLGVQWTNLAWIVSALSVGIGFGLQEIVKNFVSGLI
LLTERPVKVGDLISISGVEGDIRRINVRATEIQLSDRSIVIVPNSQLISQNLRNVTLGGSAQGVATLELMFPLDIDPEQV
QNLLFDTYKEHETILEKPAPFVRFSKLTPDGITLTVTGYVASPRIVGTTKSDLLFEILKRLGAAGIELAKPPST
>Mature_794_residues
MRNALKSLMFIALILLGSGFVAVSAADLSGTADVSTGAPLPGVSQSDLQALQLRLDGLKQQISSANNYNQLEGPQDRVQT
FILDIDRLSASLLPQQAQLAVQLGVLGAAPAEAVAAEQADIAAQRATLIEQKTKVDTALKNLAILKQSATELITQIAGIR
RTLLESELTLSTDSILNPGFWAPLVNPSADDRQRLRFFVEQVQQTGAEAWQPGQRFYTALLVVLAFVVWTLGRRLADRWL
AWVCIHRMPEGRLRRSSLAFASALATLATTAIALQLLYYACTRHVPLPPMLATFSDEFGKVVYACVLITGLSRALLSTEH
PSWRLPAVADEVANALQPFARILAAALLVLVTAVQVSNASGMSSQIVLAGRGIIALVVLVIVTTLLMRVGKVRKVLAAAG
DTQVAGNTFAGVIYTVATLAMVLSFGTLLTGYVSLARFITYELVWAFIVFSGFYLLMQLLKDSCEYFFSPRHSSGKALKQ
LLGVGDRRLEQASTLLAGFGRAALLLLAVITLFVGGIGTTLGQLANNIGTILGGAGLRKLNIVPGHLLNAMLALLIGIYL
IRALRRWLDNEFLPKTDMDPGMCASLSTLFSNIGYAVVILLTLSSLGVQWTNLAWIVSALSVGIGFGLQEIVKNFVSGLI
LLTERPVKVGDLISISGVEGDIRRINVRATEIQLSDRSIVIVPNSQLISQNLRNVTLGGSAQGVATLELMFPLDIDPEQV
QNLLFDTYKEHETILEKPAPFVRFSKLTPDGITLTVTGYVASPRIVGTTKSDLLFEILKRLGAAGIELAKPPST

Specific function: Unknown

COG id: COG3264

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI2367355, Length=299, Percent_Identity=31.438127090301, Blast_Score=137, Evalue=3e-33,
Organism=Escherichia coli, GI1786670, Length=249, Percent_Identity=35.7429718875502, Blast_Score=137, Evalue=3e-33,
Organism=Escherichia coli, GI1789291, Length=246, Percent_Identity=22.7642276422764, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR006686
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 85401; Mature: 85401

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNALKSLMFIALILLGSGFVAVSAADLSGTADVSTGAPLPGVSQSDLQALQLRLDGLKQ
CCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
QISSANNYNQLEGPQDRVQTFILDIDRLSASLLPQQAQLAVQLGVLGAAPAEAVAAEQAD
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHH
IAAQRATLIEQKTKVDTALKNLAILKQSATELITQIAGIRRTLLESELTLSTDSILNPGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCC
WAPLVNPSADDRQRLRFFVEQVQQTGAEAWQPGQRFYTALLVVLAFVVWTLGRRLADRWL
CCCCCCCCCCHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AWVCIHRMPEGRLRRSSLAFASALATLATTAIALQLLYYACTRHVPLPPMLATFSDEFGK
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
VVYACVLITGLSRALLSTEHPSWRLPAVADEVANALQPFARILAAALLVLVTAVQVSNAS
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GMSSQIVLAGRGIIALVVLVIVTTLLMRVGKVRKVLAAAGDTQVAGNTFAGVIYTVATLA
CCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
MVLSFGTLLTGYVSLARFITYELVWAFIVFSGFYLLMQLLKDSCEYFFSPRHSSGKALKQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
LLGVGDRRLEQASTLLAGFGRAALLLLAVITLFVGGIGTTLGQLANNIGTILGGAGLRKL
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
NIVPGHLLNAMLALLIGIYLIRALRRWLDNEFLPKTDMDPGMCASLSTLFSNIGYAVVIL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LTLSSLGVQWTNLAWIVSALSVGIGFGLQEIVKNFVSGLILLTERPVKVGDLISISGVEG
HHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEEEECCCCCCCCEEEECCCCC
DIRRINVRATEIQLSDRSIVIVPNSQLISQNLRNVTLGGSAQGVATLELMFPLDIDPEQV
CCEEEEEEEEEEEECCCEEEEECCHHHHHHHHCEEECCCCCCCCEEEEEEECCCCCHHHH
QNLLFDTYKEHETILEKPAPFVRFSKLTPDGITLTVTGYVASPRIVGTTKSDLLFEILKR
HHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEEEEECCCEEECCCHHHHHHHHHHH
LGAAGIELAKPPST
HCCCCCCCCCCCCC
>Mature Secondary Structure
MRNALKSLMFIALILLGSGFVAVSAADLSGTADVSTGAPLPGVSQSDLQALQLRLDGLKQ
CCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
QISSANNYNQLEGPQDRVQTFILDIDRLSASLLPQQAQLAVQLGVLGAAPAEAVAAEQAD
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHH
IAAQRATLIEQKTKVDTALKNLAILKQSATELITQIAGIRRTLLESELTLSTDSILNPGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCC
WAPLVNPSADDRQRLRFFVEQVQQTGAEAWQPGQRFYTALLVVLAFVVWTLGRRLADRWL
CCCCCCCCCCHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AWVCIHRMPEGRLRRSSLAFASALATLATTAIALQLLYYACTRHVPLPPMLATFSDEFGK
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
VVYACVLITGLSRALLSTEHPSWRLPAVADEVANALQPFARILAAALLVLVTAVQVSNAS
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GMSSQIVLAGRGIIALVVLVIVTTLLMRVGKVRKVLAAAGDTQVAGNTFAGVIYTVATLA
CCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
MVLSFGTLLTGYVSLARFITYELVWAFIVFSGFYLLMQLLKDSCEYFFSPRHSSGKALKQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
LLGVGDRRLEQASTLLAGFGRAALLLLAVITLFVGGIGTTLGQLANNIGTILGGAGLRKL
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
NIVPGHLLNAMLALLIGIYLIRALRRWLDNEFLPKTDMDPGMCASLSTLFSNIGYAVVIL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LTLSSLGVQWTNLAWIVSALSVGIGFGLQEIVKNFVSGLILLTERPVKVGDLISISGVEG
HHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEEEECCCCCCCCEEEECCCCC
DIRRINVRATEIQLSDRSIVIVPNSQLISQNLRNVTLGGSAQGVATLELMFPLDIDPEQV
CCEEEEEEEEEEEECCCEEEEECCHHHHHHHHCEEECCCCCCCCEEEEEEECCCCCHHHH
QNLLFDTYKEHETILEKPAPFVRFSKLTPDGITLTVTGYVASPRIVGTTKSDLLFEILKR
HHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEEEEECCCEEECCCHHHHHHHHHHH
LGAAGIELAKPPST
HCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 3042771 [H]