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The map label for this gene is steT [H]

Identifier: 77458570

GI number: 77458570

Start: 2704014

End: 2705378

Strand: Direct

Name: steT [H]

Synonym: Pfl01_2343

Alternate gene names: 77458570

Gene position: 2704014-2705378 (Clockwise)

Preceding gene: 77458569

Following gene: 77458576

Centisome position: 42.0

GC content: 61.68

Gene sequence:

>1365_bases
ATGACTCAAACCAATGGCCCCAAGCGGCACCTGCCGGTGTTCCAGGCATTGCTGATCACGCTGGGCATGGTCATCACCAC
CGATATTCTCAAAACCGCGCCGACCGTTGCCTTGAACGTCGGGCCGGAACATTTCTATTGGGTCTGGGTGCTTGGCGGAC
TGGCGTCGATGGCCGGGGCCTTGTGCTTTGCCGAGATGGCCACCGCGTTCCCGCATCCGGGCGGTGACTATCATTTCCTG
CGCACCGCTTATGGCGAGCGCATGGGTTTCCTGTTTGCCTGGTCGCGATTCTCGGTGATGCACACCGGGTGGATCGCGTT
GTCGGCGTTCATGTTTGCCGACTACTTCAATGCGGTCGTGCCGTTGGGGCATTACGGATCGGGGCTGTTTGCCGGTGCGA
TCATCGCTGCGCTGGTACTGCTGAATCTGACGGGCAAGCACATTGGTTTCATGACTCAGACGGTGCTGGTCGGGCTGCTT
GCTCTCGGGTTCCTGAGCATTGCCAGCGCCGGGGTCTGGCTGGCGTGGCAAGGGTTCGAACCAACGCTGCCCAGCGATCC
GGTGGTGCCCGAACACACGGGCGCGGCGGGATTTTCAGCGGCGATGATCTTCGTATTTCTGGCCTTCGGCGGCTGGAGCG
ATGCAGCGACATTGTCCGCCGAAGTGCGCGATGGTCGACGCGGGATCTTCATCGCCATGCTCGGTGCGCTGACGGTGCTG
ATGGCGATCTATCTGGCGCTGAACTGGGCGTTCGTCCAAGGGCTGGGATTCGAAGGCCTGGCGGCGAGCAACGCGCCGGC
GGTGGAATTGTTGAACCGCGCCTTCGGTGCCCCGGGCGTGCTGCTGATCCTGCTGATGGTTGGCATCGCGGCCATCGCCA
CTATCAACTCAACCTTGCTGGTCGGCGCCCGCACCACCTACGCCGCCGCCCGCGATGTGGCGCAACTGCGCCGCTTCGGT
GAGTGGGATGAGCGCGATGGCGTCCCGCGCAAGGCGTTGTTGGCGGAGGGGGCGGTGGCGTTGTTGCTGGTGTTGTTTGG
CAGTTTTACCCAGAGCGGTTTCAACACCATGGTTGAGTATCTGACGCCGGTGTACTGGCTGTTTCTGAGTTTGAGCAGTC
TCGCGTTGATCATTCTGCGCAGGCGCTTTCCTGAGGTGCCCCGGCCGGTGAGGGTGCCGCTTTATCCGGTTTTGCCGCTG
GTGTTTTTTGGGTTGTGCGTTTACATGCTGTATTCCAGCGTGACGGTGGTTGGTTTCGGCGCTTTTCTGGGGATTGGGGT
ATTGCTGGTGGGGGCGTTCTTGCTGGCCGGGTTGAGCTGCCTGGTGTCGACACCTCGGCAGGCTCTGCAACGGAGCGTAG
ATTAG

Upstream 100 bases:

>100_bases
GTCGCCGATCGGCACCAACGGCGCGTATTACTACGCCACCGCGACTTACGGCTTCTGAGTCTTTTCCGCCATGGATGGCG
GATCATCAGCGGGAACCTTC

Downstream 100 bases:

>100_bases
AAGGACACCACCGCCGGTTGCGACAACCGCAGCACCGACAAATCCCCCGTAATCCGCTTGTACGCCAAACGAATCGCCTC
GATGTCACTCTCACGCTTCG

Product: amino acid permease-associated protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MTQTNGPKRHLPVFQALLITLGMVITTDILKTAPTVALNVGPEHFYWVWVLGGLASMAGALCFAEMATAFPHPGGDYHFL
RTAYGERMGFLFAWSRFSVMHTGWIALSAFMFADYFNAVVPLGHYGSGLFAGAIIAALVLLNLTGKHIGFMTQTVLVGLL
ALGFLSIASAGVWLAWQGFEPTLPSDPVVPEHTGAAGFSAAMIFVFLAFGGWSDAATLSAEVRDGRRGIFIAMLGALTVL
MAIYLALNWAFVQGLGFEGLAASNAPAVELLNRAFGAPGVLLILLMVGIAAIATINSTLLVGARTTYAAARDVAQLRRFG
EWDERDGVPRKALLAEGAVALLLVLFGSFTQSGFNTMVEYLTPVYWLFLSLSSLALIILRRRFPEVPRPVRVPLYPVLPL
VFFGLCVYMLYSSVTVVGFGAFLGIGVLLVGAFLLAGLSCLVSTPRQALQRSVD

Sequences:

>Translated_454_residues
MTQTNGPKRHLPVFQALLITLGMVITTDILKTAPTVALNVGPEHFYWVWVLGGLASMAGALCFAEMATAFPHPGGDYHFL
RTAYGERMGFLFAWSRFSVMHTGWIALSAFMFADYFNAVVPLGHYGSGLFAGAIIAALVLLNLTGKHIGFMTQTVLVGLL
ALGFLSIASAGVWLAWQGFEPTLPSDPVVPEHTGAAGFSAAMIFVFLAFGGWSDAATLSAEVRDGRRGIFIAMLGALTVL
MAIYLALNWAFVQGLGFEGLAASNAPAVELLNRAFGAPGVLLILLMVGIAAIATINSTLLVGARTTYAAARDVAQLRRFG
EWDERDGVPRKALLAEGAVALLLVLFGSFTQSGFNTMVEYLTPVYWLFLSLSSLALIILRRRFPEVPRPVRVPLYPVLPL
VFFGLCVYMLYSSVTVVGFGAFLGIGVLLVGAFLLAGLSCLVSTPRQALQRSVD
>Mature_453_residues
TQTNGPKRHLPVFQALLITLGMVITTDILKTAPTVALNVGPEHFYWVWVLGGLASMAGALCFAEMATAFPHPGGDYHFLR
TAYGERMGFLFAWSRFSVMHTGWIALSAFMFADYFNAVVPLGHYGSGLFAGAIIAALVLLNLTGKHIGFMTQTVLVGLLA
LGFLSIASAGVWLAWQGFEPTLPSDPVVPEHTGAAGFSAAMIFVFLAFGGWSDAATLSAEVRDGRRGIFIAMLGALTVLM
AIYLALNWAFVQGLGFEGLAASNAPAVELLNRAFGAPGVLLILLMVGIAAIATINSTLLVGARTTYAAARDVAQLRRFGE
WDERDGVPRKALLAEGAVALLLVLFGSFTQSGFNTMVEYLTPVYWLFLSLSSLALIILRRRFPEVPRPVRVPLYPVLPLV
FFGLCVYMLYSSVTVVGFGAFLGIGVLLVGAFLLAGLSCLVSTPRQALQRSVD

Specific function: Exhibits an obligate exchange activity for serine, threonine and aromatic amino acids [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family [H]

Homologues:

Organism=Homo sapiens, GI187423910, Length=419, Percent_Identity=24.3436754176611, Blast_Score=119, Evalue=8e-27,
Organism=Homo sapiens, GI7657591, Length=419, Percent_Identity=24.3436754176611, Blast_Score=119, Evalue=8e-27,
Organism=Homo sapiens, GI186910308, Length=402, Percent_Identity=23.6318407960199, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI186910306, Length=402, Percent_Identity=23.6318407960199, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI186910304, Length=402, Percent_Identity=23.6318407960199, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI115648063, Length=397, Percent_Identity=23.4256926952141, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI115648022, Length=397, Percent_Identity=23.4256926952141, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI33286428, Length=450, Percent_Identity=24.6666666666667, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI9790235, Length=409, Percent_Identity=26.6503667481663, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI71979932, Length=416, Percent_Identity=23.0769230769231, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI7657683, Length=388, Percent_Identity=22.1649484536082, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI33286430, Length=238, Percent_Identity=24.7899159663866, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI87082250, Length=384, Percent_Identity=20.8333333333333, Blast_Score=74, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI32566699, Length=360, Percent_Identity=25, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71993915, Length=404, Percent_Identity=26.2376237623762, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71982608, Length=400, Percent_Identity=24.75, Blast_Score=98, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI71982612, Length=400, Percent_Identity=24.75, Blast_Score=98, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17540018, Length=434, Percent_Identity=22.8110599078341, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71995388, Length=403, Percent_Identity=26.7990074441687, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71995382, Length=403, Percent_Identity=26.7990074441687, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI193208714, Length=403, Percent_Identity=23.5732009925558, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI32566695, Length=403, Percent_Identity=23.5732009925558, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17568033, Length=409, Percent_Identity=22.9828850855746, Blast_Score=85, Evalue=8e-17,
Organism=Drosophila melanogaster, GI21357367, Length=432, Percent_Identity=25.2314814814815, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI45550968, Length=445, Percent_Identity=25.6179775280899, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI19921172, Length=445, Percent_Identity=25.6179775280899, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24651635, Length=395, Percent_Identity=26.5822784810127, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24651633, Length=395, Percent_Identity=26.5822784810127, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI221331183, Length=393, Percent_Identity=24.4274809160305, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI17647653, Length=393, Percent_Identity=24.4274809160305, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24664379, Length=393, Percent_Identity=24.4274809160305, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24641993, Length=389, Percent_Identity=22.879177377892, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24641995, Length=389, Percent_Identity=22.879177377892, Blast_Score=99, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 48653; Mature: 48522

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCC
>Mature Secondary Structure 
TQTNGPKRHLPVFQALLITLGMVITTDILKTAPTVALNVGPEHFYWVWVLGGLASMAGA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHH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HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]