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The map label for this gene is solA [H]

Identifier: 77458512

GI number: 77458512

Start: 2635450

End: 2636610

Strand: Direct

Name: solA [H]

Synonym: Pfl01_2285

Alternate gene names: 77458512

Gene position: 2635450-2636610 (Clockwise)

Preceding gene: 77458511

Following gene: 77458513

Centisome position: 40.93

GC content: 63.14

Gene sequence:

>1161_bases
ATGGAACGATGCGAAGCACTGGTCATCGGCCTCGGCGCCATGGGCGCGGCCACGGTGTATCAAATGGCGAAGGCCGGGGT
CAACGTGGTCGGCATCGACCGCCACCATCCACCGCACACATTCGGCTCCAGCCATGGGGACACCCGCATCACCCGGTTGT
CCGTGGGCGAGGGCGCGCAATACGTGCCCATCGTGCGCAACTCCCACCGCATCTGGCGCGAACTGGAAGCGCTGTCGGGC
GAGTCCCTGTTCGAACAGTCCGGCCTGCTGGTGCTGACCTCCAGTCCCGACCTCGACCCCGCCGACGAAACCGACTTCAC
CCTGCGCACCATCGCCCTGGCACAGACCTACGGCATCGAACACGAAGTCTTCGACGCTGCCCAGATCCGCCAGCGCTTTC
CGCAGTTTGCCCAGGTGCGCGACGACGCCATTGGCTACTTCGAGCCCGAAGGTGGTTTCGTCAGGCCCGAACGCTGCATC
GACGTGCAACTCAGACTGGCCGAACAACACGGCGCCACGCTCTACAAGGGCGAGACCGTGACCCACATAAGCTCGGACGA
ACAGGGCGTCACCGTCACCACCGACCAGCGCACTGTGCGCGCGGCCAAACTGGTGGTCACCGCCGGCAACTGGGCGGGCG
GCTTGCTCGGCGCACCGTTCGACAGACTGCTCAGCGTCTATCGGCAAAAACTGTTCTGGTTCGAAACCGAGCCCGACGCA
GGACTGGTCGGCCACTCACCCACGTTCATCTTCACTCATGGCCCGGACGACGATTTCTATGGGTTTCCCGCGTTGCCGGG
GGAGGGCAGTTTGAAAGTGGCGACGGCGCAGTATCACAGCACGTCCACGCCTGAAACTCTGGATCGCACAGTCTCGGCCG
AGGAAGAACGCGAGATGTACGAACAGCAGGTGAAGGGGCGCATTGCCGGGCTGACGGATCGGGTAGTGAAGTCAGCGGTT
TGCGCCTACACCGTCACGCCGGATCGGCATTTCATCATTGATGAGCATCCACGGTTGCAGCACACGTTGGTGGTGTCGGC
GTGCTCCGGGCATGGGTTCAAACACTCGGCGGCGTTGGGGGAGGCGTTTGCGCAGTGGTGTTTGCGAGGGGAGAGTGAGC
TGGATCTTTCGTTGTTTTCGGTGGGGCGGTTTGAGGCATAG

Upstream 100 bases:

>100_bases
CTCGCTTCCCGCATTTTTGCCAGCGTGCGGCTTTCAGCGGATTGTTTTCCATCGCCTGATCCGCTTCACTGTGGCTCTTT
TGCCTGAGCGGAAATCAATC

Downstream 100 bases:

>100_bases
TGCCCACTATTCGAAAACAGATCCATTTAATGAAAATAGATTCGCCCCTTCATGGGGAGCGAACCGAAACCCCGCAAGGA
ACGCACATGAATTTCTTCAA

Product: N-methyltryptophan oxidase

Products: NA

Alternate protein names: MSOX [H]

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MERCEALVIGLGAMGAATVYQMAKAGVNVVGIDRHHPPHTFGSSHGDTRITRLSVGEGAQYVPIVRNSHRIWRELEALSG
ESLFEQSGLLVLTSSPDLDPADETDFTLRTIALAQTYGIEHEVFDAAQIRQRFPQFAQVRDDAIGYFEPEGGFVRPERCI
DVQLRLAEQHGATLYKGETVTHISSDEQGVTVTTDQRTVRAAKLVVTAGNWAGGLLGAPFDRLLSVYRQKLFWFETEPDA
GLVGHSPTFIFTHGPDDDFYGFPALPGEGSLKVATAQYHSTSTPETLDRTVSAEEEREMYEQQVKGRIAGLTDRVVKSAV
CAYTVTPDRHFIIDEHPRLQHTLVVSACSGHGFKHSAALGEAFAQWCLRGESELDLSLFSVGRFEA

Sequences:

>Translated_386_residues
MERCEALVIGLGAMGAATVYQMAKAGVNVVGIDRHHPPHTFGSSHGDTRITRLSVGEGAQYVPIVRNSHRIWRELEALSG
ESLFEQSGLLVLTSSPDLDPADETDFTLRTIALAQTYGIEHEVFDAAQIRQRFPQFAQVRDDAIGYFEPEGGFVRPERCI
DVQLRLAEQHGATLYKGETVTHISSDEQGVTVTTDQRTVRAAKLVVTAGNWAGGLLGAPFDRLLSVYRQKLFWFETEPDA
GLVGHSPTFIFTHGPDDDFYGFPALPGEGSLKVATAQYHSTSTPETLDRTVSAEEEREMYEQQVKGRIAGLTDRVVKSAV
CAYTVTPDRHFIIDEHPRLQHTLVVSACSGHGFKHSAALGEAFAQWCLRGESELDLSLFSVGRFEA
>Mature_386_residues
MERCEALVIGLGAMGAATVYQMAKAGVNVVGIDRHHPPHTFGSSHGDTRITRLSVGEGAQYVPIVRNSHRIWRELEALSG
ESLFEQSGLLVLTSSPDLDPADETDFTLRTIALAQTYGIEHEVFDAAQIRQRFPQFAQVRDDAIGYFEPEGGFVRPERCI
DVQLRLAEQHGATLYKGETVTHISSDEQGVTVTTDQRTVRAAKLVVTAGNWAGGLLGAPFDRLLSVYRQKLFWFETEPDA
GLVGHSPTFIFTHGPDDDFYGFPALPGEGSLKVATAQYHSTSTPETLDRTVSAEEEREMYEQQVKGRIAGLTDRVVKSAV
CAYTVTPDRHFIIDEHPRLQHTLVVSACSGHGFKHSAALGEAFAQWCLRGESELDLSLFSVGRFEA

Specific function: Catalyzes the oxidative demethylation of sarcosine [H]

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MSOX/MTOX family. MSOX subfamily [H]

Homologues:

Organism=Homo sapiens, GI60499001, Length=391, Percent_Identity=28.1329923273657, Blast_Score=145, Evalue=5e-35,
Organism=Escherichia coli, GI1787298, Length=388, Percent_Identity=32.7319587628866, Blast_Score=188, Evalue=5e-49,
Organism=Caenorhabditis elegans, GI25147318, Length=398, Percent_Identity=26.3819095477387, Blast_Score=130, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI115535191, Length=388, Percent_Identity=23.7113402061856, Blast_Score=107, Evalue=8e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR006281 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 42447; Mature: 42447

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERCEALVIGLGAMGAATVYQMAKAGVNVVGIDRHHPPHTFGSSHGDTRITRLSVGEGAQ
CCCCEEEEEECCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCEEEEEECCCCCE
YVPIVRNSHRIWRELEALSGESLFEQSGLLVLTSSPDLDPADETDFTLRTIALAQTYGIE
EEEEEECCHHHHHHHHHHCCCHHHHCCCEEEEECCCCCCCCCCCCEEEEEEEHHHHCCCC
HEVFDAAQIRQRFPQFAQVRDDAIGYFEPEGGFVRPERCIDVQLRLAEQHGATLYKGETV
HHHHHHHHHHHHCHHHHHHHHCCCCEECCCCCEECCCHHEEEEEEEEHHCCCEEECCCEE
THISSDEQGVTVTTDQRTVRAAKLVVTAGNWAGGLLGAPFDRLLSVYRQKLFWFETEPDA
EEECCCCCCEEEEECCCEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHEEEECCCCC
GLVGHSPTFIFTHGPDDDFYGFPALPGEGSLKVATAQYHSTSTPETLDRTVSAEEEREMY
CCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHCCCHHHHHHH
EQQVKGRIAGLTDRVVKSAVCAYTVTPDRHFIIDEHPRLQHTLVVSACSGHGFKHSAALG
HHHHHHHHCCHHHHHHHHHHEEEEECCCCEEEECCCCCCEEEEEEEECCCCCCCHHHHHH
EAFAQWCLRGESELDLSLFSVGRFEA
HHHHHHHHCCCCCCCEEEEECCCCCC
>Mature Secondary Structure
MERCEALVIGLGAMGAATVYQMAKAGVNVVGIDRHHPPHTFGSSHGDTRITRLSVGEGAQ
CCCCEEEEEECCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCEEEEEECCCCCE
YVPIVRNSHRIWRELEALSGESLFEQSGLLVLTSSPDLDPADETDFTLRTIALAQTYGIE
EEEEEECCHHHHHHHHHHCCCHHHHCCCEEEEECCCCCCCCCCCCEEEEEEEHHHHCCCC
HEVFDAAQIRQRFPQFAQVRDDAIGYFEPEGGFVRPERCIDVQLRLAEQHGATLYKGETV
HHHHHHHHHHHHCHHHHHHHHCCCCEECCCCCEECCCHHEEEEEEEEHHCCCEEECCCEE
THISSDEQGVTVTTDQRTVRAAKLVVTAGNWAGGLLGAPFDRLLSVYRQKLFWFETEPDA
EEECCCCCCEEEEECCCEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHEEEECCCCC
GLVGHSPTFIFTHGPDDDFYGFPALPGEGSLKVATAQYHSTSTPETLDRTVSAEEEREMY
CCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHCCCHHHHHHH
EQQVKGRIAGLTDRVVKSAVCAYTVTPDRHFIIDEHPRLQHTLVVSACSGHGFKHSAALG
HHHHHHHHCCHHHHHHHHHHEEEEECCCCEEEECCCCCCEEEEEEEECCCCCCCHHHHHH
EAFAQWCLRGESELDLSLFSVGRFEA
HHHHHHHHCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1368683 [H]