Click here to switch to the map view.

The map label for this gene is katA [H]

Identifier: 77458489

GI number: 77458489

Start: 2595603

End: 2597036

Strand: Reverse

Name: katA [H]

Synonym: Pfl01_2262

Alternate gene names: 77458489

Gene position: 2597036-2595603 (Counterclockwise)

Preceding gene: 77458490

Following gene: 77458485

Centisome position: 40.34

GC content: 61.58

Gene sequence:

>1434_bases
ATGAACAAGCTGACGACTGCCGCGGGCGCGCCCGTGGTTGATAACAACAACGTACAGACCGCCGGCCCCAGAGGCCCGAT
GCTGTTGCAGGACGTATGGTTGCTGGAAAAACTGGCGCACTTCGATCGGGAAGTCATCCCCGAGCGGCGCATGCACGCCA
AGGGTTCCGGCGCGTTCGGCACCTTCACCGTGACCCACGACATCACCCGTTTCACCAAGGCCAGGCTGTTTTCCAGCGTG
GGCAAGACCACCGATGTGTTCGTCCGGTTTTCGACCGTGGCCGGGGAGCGTGGCGCGGCGGATGCCGAGCGTGACATCCG
TGGATTCGCCATCAAGTTCTATACCGAGCAAGGCAACTGGGACTTGGTGGGCAACAACACGCCGGTGTTCTTTCTGCGCG
ATCCGTTGAAATTCCCCGACCTCAACCATGCGGTCAAACGCGACCCACGCACCAACATGCGCAGCGCCCGCAACAATTGG
GATTTCTGGACGTTGCTGCCGGAAGCGCTGCACCAGGTCACGATTGTCATGAGCGATCGTGGCCTGCCGCGCACCTACCG
CCACATGCACGGTTTCGGCAGCCACACCTTCAGTTTCATCAGCCCGGCGAACGAACGTTTCTGGGTGAAGTTCACCTGGA
AGACTCAACAAGGCATCGAAAACCTGACCGACCAACAGGCCGCGACCCTGATCGGCGATGACCGCGAAAGCGCCCAGCGC
GACCTGTACAACGCCATCGAGGAAGGTCACTTCCCGCAATGGAAGCTCTACGTGCAAGTGATGCCGGAGCTGGATGCCGA
GACTTACCCGATCAACCCGTTCGACCTGACCAAGGTCTGGCCCCACGCGGATTACCCGCTGATCGAAGTTGGTGTGCTCG
AACTCAACCGTAATCCGGACAACTACTTCGCCGACGTCGAACAGGCGGCCTTCAACCCGGCCAACGTGGTGCCCGGCATC
AGTTTCTCACCGGACAAAATGCTCCAGGCGCGCCTTTTCTCCTATGGCGATGCCCAGCGCTATCGCGTCGGCGTCAACCA
TCATCAGATCCCCGTGAATGCCCCACGCTGCCCGGTCAACAGTTATCACCGGGACGGCCAGATGCGCACCGATGCGAACG
CGGGCAGCACAATCGGGTACGAGCCCAACAGCTATGGCCAGTGGGCCGAGCAACCGGATTTCAGCGAGCCACCGCTGGCC
CTGAAAGGCAGCGCCGGGCACTGGAATCACCGTGAGGACGACGATTACTTCTCGCAACCGGGCGCGCTGTTCCGGGCCAT
GTCCACCGCCCAGCAACAGGTCTTGTTCGAGAACACCGCGCGCTCGATCCATGGCGCCAGTGCCCAGACCCGGCAACGCC
ACATCGATAACTGCACTCGTGCCGATCCGGCGTACGGTGCGGGTGTTGCACAGGCCATCGAAGCACTGGGCTGA

Upstream 100 bases:

>100_bases
AACCACACCTTCGTACGATCCGGCGACACCATGGTGCAATAGATCGCGCCCGGGGCTTTTGATGTGATGACGGGAAACCG
ACAAAAGCCAGGAGTTGCGC

Downstream 100 bases:

>100_bases
TCCGCAATGACTTGAGCAGGGCAAGCAGGATTGATCCTGTTTGCCCTGCTGCCGTTGTCAGTCCTCTACGATGCTTTTCG
CTTCAAGAAACGCCTCCAGC

Product: catalase-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MNKLTTAAGAPVVDNNNVQTAGPRGPMLLQDVWLLEKLAHFDREVIPERRMHAKGSGAFGTFTVTHDITRFTKARLFSSV
GKTTDVFVRFSTVAGERGAADAERDIRGFAIKFYTEQGNWDLVGNNTPVFFLRDPLKFPDLNHAVKRDPRTNMRSARNNW
DFWTLLPEALHQVTIVMSDRGLPRTYRHMHGFGSHTFSFISPANERFWVKFTWKTQQGIENLTDQQAATLIGDDRESAQR
DLYNAIEEGHFPQWKLYVQVMPELDAETYPINPFDLTKVWPHADYPLIEVGVLELNRNPDNYFADVEQAAFNPANVVPGI
SFSPDKMLQARLFSYGDAQRYRVGVNHHQIPVNAPRCPVNSYHRDGQMRTDANAGSTIGYEPNSYGQWAEQPDFSEPPLA
LKGSAGHWNHREDDDYFSQPGALFRAMSTAQQQVLFENTARSIHGASAQTRQRHIDNCTRADPAYGAGVAQAIEALG

Sequences:

>Translated_477_residues
MNKLTTAAGAPVVDNNNVQTAGPRGPMLLQDVWLLEKLAHFDREVIPERRMHAKGSGAFGTFTVTHDITRFTKARLFSSV
GKTTDVFVRFSTVAGERGAADAERDIRGFAIKFYTEQGNWDLVGNNTPVFFLRDPLKFPDLNHAVKRDPRTNMRSARNNW
DFWTLLPEALHQVTIVMSDRGLPRTYRHMHGFGSHTFSFISPANERFWVKFTWKTQQGIENLTDQQAATLIGDDRESAQR
DLYNAIEEGHFPQWKLYVQVMPELDAETYPINPFDLTKVWPHADYPLIEVGVLELNRNPDNYFADVEQAAFNPANVVPGI
SFSPDKMLQARLFSYGDAQRYRVGVNHHQIPVNAPRCPVNSYHRDGQMRTDANAGSTIGYEPNSYGQWAEQPDFSEPPLA
LKGSAGHWNHREDDDYFSQPGALFRAMSTAQQQVLFENTARSIHGASAQTRQRHIDNCTRADPAYGAGVAQAIEALG
>Mature_477_residues
MNKLTTAAGAPVVDNNNVQTAGPRGPMLLQDVWLLEKLAHFDREVIPERRMHAKGSGAFGTFTVTHDITRFTKARLFSSV
GKTTDVFVRFSTVAGERGAADAERDIRGFAIKFYTEQGNWDLVGNNTPVFFLRDPLKFPDLNHAVKRDPRTNMRSARNNW
DFWTLLPEALHQVTIVMSDRGLPRTYRHMHGFGSHTFSFISPANERFWVKFTWKTQQGIENLTDQQAATLIGDDRESAQR
DLYNAIEEGHFPQWKLYVQVMPELDAETYPINPFDLTKVWPHADYPLIEVGVLELNRNPDNYFADVEQAAFNPANVVPGI
SFSPDKMLQARLFSYGDAQRYRVGVNHHQIPVNAPRCPVNSYHRDGQMRTDANAGSTIGYEPNSYGQWAEQPDFSEPPLA
LKGSAGHWNHREDDDYFSQPGALFRAMSTAQQQVLFENTARSIHGASAQTRQRHIDNCTRADPAYGAGVAQAIEALG

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=472, Percent_Identity=51.6949152542373, Blast_Score=501, Evalue=1e-142,
Organism=Escherichia coli, GI48994891, Length=490, Percent_Identity=41.8367346938776, Blast_Score=357, Evalue=1e-99,
Organism=Caenorhabditis elegans, GI71998444, Length=473, Percent_Identity=49.2600422832981, Blast_Score=471, Evalue=1e-133,
Organism=Caenorhabditis elegans, GI25151141, Length=472, Percent_Identity=47.6694915254237, Blast_Score=454, Evalue=1e-128,
Organism=Caenorhabditis elegans, GI25147792, Length=472, Percent_Identity=47.6694915254237, Blast_Score=453, Evalue=1e-128,
Organism=Saccharomyces cerevisiae, GI6320462, Length=483, Percent_Identity=45.7556935817805, Blast_Score=398, Evalue=1e-111,
Organism=Saccharomyces cerevisiae, GI6321525, Length=386, Percent_Identity=41.7098445595855, Blast_Score=306, Evalue=4e-84,
Organism=Drosophila melanogaster, GI17981717, Length=474, Percent_Identity=47.0464135021097, Blast_Score=442, Evalue=1e-124,
Organism=Drosophila melanogaster, GI19920968, Length=475, Percent_Identity=45.2631578947368, Blast_Score=429, Evalue=1e-120,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 53783; Mature: 53783

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKLTTAAGAPVVDNNNVQTAGPRGPMLLQDVWLLEKLAHFDREVIPERRMHAKGSGAFG
CCCCCCCCCCCEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCEE
TFTVTHDITRFTKARLFSSVGKTTDVFVRFSTVAGERGAADAERDIRGFAIKFYTEQGNW
EEEEHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCHHHCCCEEEEEEEEECCCE
DLVGNNTPVFFLRDPLKFPDLNHAVKRDPRTNMRSARNNWDFWTLLPEALHQVTIVMSDR
EEECCCCCEEEEECCCCCCCCCHHHHCCCCHHHHHHCCCCCHHHHHHHHHCEEEEEECCC
GLPRTYRHMHGFGSHTFSFISPANERFWVKFTWKTQQGIENLTDQQAATLIGDDRESAQR
CCCHHHHHHHCCCCCCEEEECCCCCEEEEEEEECHHHHHHHHHHHHHHHHHCCCHHHHHH
DLYNAIEEGHFPQWKLYVQVMPELDAETYPINPFDLTKVWPHADYPLIEVGVLELNRNPD
HHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCHHEECCCCCCCEEEEEEEEECCCCC
NYFADVEQAAFNPANVVPGISFSPDKMLQARLFSYGDAQRYRVGVNHHQIPVNAPRCPVN
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCC
SYHRDGQMRTDANAGSTIGYEPNSYGQWAEQPDFSEPPLALKGSAGHWNHREDDDYFSQP
CHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCHHHCCC
GALFRAMSTAQQQVLFENTARSIHGASAQTRQRHIDNCTRADPAYGAGVAQAIEALG
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MNKLTTAAGAPVVDNNNVQTAGPRGPMLLQDVWLLEKLAHFDREVIPERRMHAKGSGAFG
CCCCCCCCCCCEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCEE
TFTVTHDITRFTKARLFSSVGKTTDVFVRFSTVAGERGAADAERDIRGFAIKFYTEQGNW
EEEEHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCHHHCCCEEEEEEEEECCCE
DLVGNNTPVFFLRDPLKFPDLNHAVKRDPRTNMRSARNNWDFWTLLPEALHQVTIVMSDR
EEECCCCCEEEEECCCCCCCCCHHHHCCCCHHHHHHCCCCCHHHHHHHHHCEEEEEECCC
GLPRTYRHMHGFGSHTFSFISPANERFWVKFTWKTQQGIENLTDQQAATLIGDDRESAQR
CCCHHHHHHHCCCCCCEEEECCCCCEEEEEEEECHHHHHHHHHHHHHHHHHCCCHHHHHH
DLYNAIEEGHFPQWKLYVQVMPELDAETYPINPFDLTKVWPHADYPLIEVGVLELNRNPD
HHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCHHEECCCCCCCEEEEEEEEECCCCC
NYFADVEQAAFNPANVVPGISFSPDKMLQARLFSYGDAQRYRVGVNHHQIPVNAPRCPVN
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCC
SYHRDGQMRTDANAGSTIGYEPNSYGQWAEQPDFSEPPLALKGSAGHWNHREDDDYFSQP
CHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCHHHCCC
GALFRAMSTAQQQVLFENTARSIHGASAQTRQRHIDNCTRADPAYGAGVAQAIEALG
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA