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The map label for this gene is tycC [H]

Identifier: 77458438

GI number: 77458438

Start: 2497181

End: 2503591

Strand: Direct

Name: tycC [H]

Synonym: Pfl01_2211

Alternate gene names: 77458438

Gene position: 2497181-2503591 (Clockwise)

Preceding gene: 77458433

Following gene: 77458439

Centisome position: 38.79

GC content: 64.45

Gene sequence:

>6411_bases
ATGAACCAATTTGCTGCCGACGCGGCGGACGGTCTGTCCGCGATTTCCGAGGCTTTCCCGCTGACCGCTGCCCAGCGCGA
TATCTGGCTCGATCAATTGCGTCAGGGAAATTCGCCGATGTACAACATCGGTGGCTATGTCGAACTGACCGGGCCGCTGG
ATCCGGCGCTGATGCAGACAGCTCTCGAGGGTCTCGTGGCCCGGCATGACGCCATGCGCACCAGCCTGCTGCCGGGGGCC
GGCGAGCATGGGCTGCCATTGCAGCGTTTCGCGCGATCGATGCCGGTGCCGATGCCGGTGCACGATTTACGCAGCCATCC
CGATCCATACGCCGCAGCGCGCCAACTGACGCAGGAAAACATCGAGCGGCTGTTTACGCTGGATGGCGGGCCGTTGTTTC
GGTTTAGTCTGCTCTGGCTCGATGACGACCGTCATTGGCTCTCACTCCAGGCCCATCACTTGATCGTTGATGGCTGGGGG
TTCGGCGAGATGCTCAAGTCCCTCGACGAGATCTACAACGCGCTCGCGCTCGGGCAACTGCCGCCCGATTCGGCGCCGTC
CTATGTCGATTTCATCCGCGACGATGCGCGGTATTTTCAGTCCGCCCGTTATGCCCGCGACCGTGCGTATTGGCTGGACA
AATACCAGCACCGTCCCGAGCCGCTGTTGTTGCCGCGTTACCAGGAGCGCTTTGCCGGCGCTGCGGCACCCACCCGGATT
TTCTCGCAGGTGTTTCCGGCTCGCTTGCACGAGCGCATGAAGCAGGTGGCCCGAGAGTACGGTGCGTCGGCGTTTCACGT
GTTGCTGGCAGCGATCCATGTGTACTTCAGCCGCAGCGCCCAGCGTGACGAATGGGTGGTGGGCGTGCCGCTGCTCAACC
GTTCCGGCGCCCGGTTCAAATCGACCCTGGGGCTGTTCACCCAGGTCAGCGCGGTGCGCATGGGGTTTGGTCGCGAGTTG
TCATTCAAGACGCTGGTCAAGGCGATTCACGACGAATTGAAAAAAGACTTCCGCCACCAGCGTTTTCCCTTGAGCGAGAT
GAACCGCGCCCTCGGTTTGCTGCGCGAGGATCGCTCGCAGCTGTTCGAAGTGACCGTGTCCTATGAGCGCGACGCCCATG
AATATCGCTATGGCGAAGCACAGGGGCGGGTGGTCAAAGTGTCGAACCACGAAGAGGGTACGCCGCTGTCCGTGCACTTG
CGCAGCAGCCGGGGCGACGACGAGGACAGTCTCTACATGGTGTACAACGAGGCCTACTTTGACGCCAACGAAGTCGCGGC
GCTGAGCGGGCGCTTGCTGTGGGTGCTGGAGCAGGGGCTTGAAGAACCGGCGCTGGCAGTGGGCGACTTCAGCCTGAGCC
TGCCGGCCGAATCGGCGTTGCTGCAGCAATGGAATGACACGCGCGTTGAATTCCCCCAAGACCTGACCATTCACCAGCGC
ATCGAAGCGCAATCGGCGGCGCGGCCGGACGCGGTAGCGGCTGAATCCCTGGGACAGCAGCTGACCTATGCCGAGCTGAA
CCGACAGGCCAACGCCCTGGCCCATCATTTGATCGGGCTCGGCGTGCGACCCGACGACCGTGTGGCGCTGGTCGCCCGAC
GAGGGCTGGACACGCTGGTCGCGCTGCTGGCGATTCTCAAATCCGGCGCCGGTTACGTGCCGGTCGATCCGGCCCATCCT
GCGGAACGCCTGAGCTATTTATTGCGCGACAGTGCTCCGGCCGTGGTCCTGACCCAGCGCGATTTGCGCGAACGCTTGCC
GGTGCTGGACGTGTCGCTGATCGAAATCGATTCGCGCGGCTGGCCGATCAACGATCTCAACCCCGACGTCTCGGGGCTGA
CCTCCGCGCACCTGGCCTACGTGATCTACACCTCCGGCTCCACCGGCCAGCCCAAGGGCGTGATGGTCGAACATCACACG
TTATCGAATCTGGTCGACTGGCATTGCACAGCCTTCGATCTGTGGGCCGGTCGCCACGCTTCAAGCCTTGCCGGCTTCGG
CTTCGACGCCATGGCCTGGGAAGTCTGGCCCGCCCTGTGTGTCGGCGCGACCCTGCACCTGGCGCCGTCTCGTGACGGTG
GCGAAGACATCGACGCGCTGCTCGACTGGTGGCGCGCGCAACCGCTGGACGTGAGTTTCCTGCCGACCCCGATTGCCGAA
TACGCCTTCAGTCGCCACGTCGAACACCCGACCCTGCGCACGCTGCTGATCGGCGGTGATCGCCTGCGTCAGTTCAATCG
CGAGCAGACGTTCGCGGTGATCAACAACTACGGCCCGACCGAAGCGACGGTGGTCGCTACCTCGGGCCGAATCGGGCCAG
GCCGGACGCTGCACATCGGCAAACCCGTGAGCAATGCCACGGCCTATCTGCTGGATGACCGACAACGCCCGGTGCCGATT
GGCGTGGCCGGTGAGCTGTACGTCGGCGGCGCCGGGGTGGCACGGGGTTACTTCAACCGGCCGGAGCTGACCGCCGAACG
TTTCCTCGACGATCCATTCAGCCGCCAGCCCAACGCGCGGATGTACCGCACCGGCGACCTCGCACGCTGGCGCCCGGACG
GCACTATCGAATACCTGGGCCGCAACGACGATCAGGTGAAAATCCGTGGGGTGCGCATCGAACCCGGCGAGATTGAAGCG
GCGTTGAGCCGCCATGAATCCGTGCGCGATGCGGTGGTGCAGGTACGCGACGGGCAATTGCTGGCCTGGTTCACCGAACG
CCAGCCGCTGGATATCACGCAGCTGCATGCTCACCTCAAGACCCGTCTGCCCAGCGCGATGCTGCCATCGGCTTACGTAC
GCTTGACGGCGTTGCCCCTGACGGCCAACGGCAAACTGGATCGCCAGGCGTTGCCGGCACCGGGGCCGGAGGCATTGATC
CGCCGCGAGTACGAGGCCCCGCAAGGCGACGTCGAAATCCTCCTGGCGCAGATTTGGGCCGAGGTGCTGCAAGTCGAAAA
GGTCGGGCGTCACGATCACTTCTTTGAACTCGGCGGGCACTCGTTGCTGGCGGTCAACCTGATCGAACGCATGCGCCAGC
TCGGCATGAGCAGCGATGTGCGCGTGCTGTTCGGCCAGCCGACCCTGGCGGCACTGGCCGCGTCGGTGGGCACTGGCCGC
GAGGTCGAAGTGCCGGCCAACCGCATTCCGCAAGGTTGCACGCGGATCACGCCGGACCTGTTGCCGTTGGTTGAACTGGA
TCAGGCCACCCTCGACCGGATCATCGCCACGGTGCCGGGCGGGGCGGCCAACGTGCAGGATATTTATCCGTTGGCGCCGT
TGCAGGAAGGCATTCTTTATCACCACATCACTGCCGCGCCGGGCGATCCATACCTGCTGCAATCGCAACTGGCGTTCGCC
AGCGTCGAGCGGGTCGAGGCCTATGCGGGCGCGTTGCGTCAGGTCATGGCGCGCCACGACATCCTGCGCACCGCCGTGGT
CTGGGAAGGTTTGACCACTCCGGTGCAGGTGGTCTGGCGCGAAGCCGAACTGCCGGTGCAGGAAATTACCTTCGATCCGG
CCGAGGGCGATGTCCTCGCGCAACTGCACGCGCGTTTCGATGCTCGTCGCTATCGCATCGACGTCAGTCAGGCGCCGCTG
ATCCGGTTGATGTATGCGCGCGATCCGGCCCACGGGCGGATCGTGGCGATTCTATTGTTCCATCACCTGGCGCTGGATCA
CATTGCGCTGGAAGTCCTGCGCCACGAAATGCGCGCCAACCTGTTGGGGCAGGGCGAACTGCTGTCGCCAGCGGTGCCGT
ATCGCAATTATGTAGCGCAGACCCGACTCGGTGTCAGCGAGCAGGAACATGAAGCGTTCTTCCGCGAGATGCTTGCCGAT
ATCGACGAACCGACCCTGCCGTTCGGTTTGCAGGACGTGCAGGGCGACGGGCGTGGTATCGATGAAGCCGTACGCACGCT
TGCGCCTGAACTGGACCGGCGATTGCGCCTTCAGGCGCGGCAGGCCGGCGTCAGCGTGGCCAGCCTGATTCACCTGGCCT
GGGCGCAGGTGCTGGCGGCGACCTCGGGGCAGGAGCACGTGGTGTTCGGCAGTGTTTTTATGGGCCGTATGCAGGGCGGC
GAGGGCGCGGACCGGGCGCTCGGGGTGTTCATCAATACTTTGCCATTGCGGGTGGACATGGACCGGAGCGCGCAGGAGGC
GGTTCAGCTCACCCACGCCCGACTGACCGATCTGCTCGGGCACGAACATGCATCACTGGCGCTGGCCCAGCGTTGCAGCG
GCGTTGCGTCACCGGCACCGCTGTTCAGTGCGTTGCTCAACTATCGGCACACCGACCTTGAGGCCCAGGAATCGGCGTCG
GACCAAGCCTGGCAAGGCATCCAGACCCTGGACAACGAAGAGCGCACCAACTACCCGATGACCCTGAGCGTCGATGATCT
GGGCAACGCCTTGCAGATCACCACGCGGACCCTGATCAGCATCGGTGCCCGGCGCATCGGCGACTACGTGCAGACCGCGT
TGCAGGCACTGGTCGATACCCTTGAGCAGGCACCGCAACAGCCGCTGAATCGCTTGCCGATACTGCCGGCAGCAGAGCTT
GAGCAATTGCTGGTCGAGTTCAATGCCAGCGAAGTCGATTGCCCGCTCGATCAGCCGCTTCAGGTGTTGTTCGAGCAACA
AGTCCAGCGCAGGCCGGACGCCATCGCATTGCAGGCTGGCGAGCAACAACTGACCTATCGCCAATTGAACGAACAGGCCA
ACCGTCTGGCGCATCATCTACGCGAGCACGGCGTGCAACCCGATTCGCGGGTGGCGATCTGTGTCGAACGCAGCCTGGAC
CTGGTGGTCGGCCTGCTCGGCATTCTCAAGGCGGGCGGCGCGTACGTGCCGCTGGATCCCGACTATCCGCTGGAACGCCT
GCATTACATGCTGCAGGACAGCGCCCCGGTGGCGGTGCTGGTCCATGACGTTACCCGCAATTTGTTGGGCGATCCGGGTG
TGCCGGTCATCGATTTCGACCGTTGCACCTGGCAGCACGCGTCGACTGAAAACCTGCAAATACCGGGTCTGAGCGCTTCA
AACCTGGCCTACATGATCTACACCTCGGGCTCCACCGGCACGCCGAAGGGCGTGATGATCGAACACCGAAGCGCCTGCAA
CATGGTGCACTGGGGCTCGCAGATCAGCCCGCCGACCGAGCACGGCGCGCTGTTGCAGAAGGCGCCGTTCAGCTTCGACA
GTTCGGTGTGGGAGATTTTCTGGCCGCTGTGTTCCGGCCTGCGGCTGGTGCTGGCGCGTCCCGACGGCAATCGCGATTCG
GCCTATGTAACCCGAGTGATTCGCGAACGGCAGATCACCGTGGTCAAGTTCGTGCCGGCGCTGCTGCAACAGTTCATCGA
ACAGGACGATGCCAGCCAGTGCACCAGCCTGACCGACGTGCTCAACGGTGGCGGTGAGCTGACCGCCGCACTGGCCCGTC
GCGTCCGCGAGCGCCTGCCATGGGTGCGTCTGCATAACGTCTACGGCCCGACCGAAACCACCGTCGACAGCACCGGCTGG
ACACTGGAACCGGACCAACCGGTGCCGGAGGCCGTGGTGCCAATCGGCAAGGCCCTGAGCAATACCCGGCTCTACGTGCT
GGACGCCCACGATCAACCGGTGCCATTCGGCGTCAGCGGCCACCTGCACATCGGCGGGGTCGGGGTCGCGCGGGGGTATC
TGGGCTTGTCGCAGATGCAGGCCGAGCGCTTCATCGACAGCCCGTTCGTGGCCGGTGATCGCCTGTACCGTACCGGCGAT
CTGGTGCGCTACCGGGCGGACGGCAACCTCGAATTCCTCGGCCGCAACGACTTCCAGATCAAGCTGCGCGGTCTGCGTCT
GGAACCGGGGGAAATCGAGGCGCGACTGATCGAGCATCCCGCCGTGCGTGAAGCGGTGGTGCTGGTGCGGGACGAGCGGC
TGGTGGCGTATTTTACCGGGCGCGAAGGCTTCGACGCGCCCCCCATCGAAACCTTGCGCGCCCATGTGCTGGAGCGTTTG
CCGGAGTACATGGCACCGGGCGCTTACGTAAAACTCGACGCGTTGCCCCTGACTCCCAACGACAAGGTCGACCGCAAAGC
CTTGCCGGCACCGGGAGCGGAGGCGGTACTCAGTCGCCGCTACGAGGCGCCCGAGGGCGAAGTCGAAATCCGGCTGGCAC
AGATCTGGGCCGAAGTGCTGCAACTGGAGCAGGTCGGGCGCAATGACCACTTCTTTGAGCTGGGCGGGCATTCGTTGCTG
GCGGTCAGCCTGGTGGCCCGCATGCGTCAGGCCGGGCTGCACGTCGATGCGCGGACGCTGTTCAGCCAGCCGACTCTGGC
CGCGCTGGCGGCGCAAACCTCGGACCAGGCAAAACAGCTGGAAGTGCCGCCAACCACCATACCGACGCTCAACCGCAAAC
GCCGGCTCTGA

Upstream 100 bases:

>100_bases
CAGGGTTGTACGAAGAGAGGGAAGTTGTCCGGGTTTCACGTGTCATGCGGGTTTCAGGGCCGATGCTTGAATACGCGCCA
AATCACGTGAGATGGATCTT

Downstream 100 bases:

>100_bases
GCCGACACCGGCGCCGACTCGCGGTTCCCGCGGATCGGCGCCATGACTGATCGGTCACGGGGCTTGTCCCCGCTTCCCAT
GTCAGACACCCAAGCCCCGA

Product: amino acid adenylation

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: Tyrocidine synthase III; ATP-dependent asparagine adenylase; AsnA; Asparagine activase; ATP-dependent glutamine adenylase; GlnA; Glutamine activase; ATP-dependent tyrosine adenylase; TyrA; Tyrosine activase; ATP-dependent valine adenylase; ValA; Valine activase; ATP-dependent ornithine adenylase; OrnA; Ornithine activase; ATP-dependent leucine adenylase; LeuA; Leucine activase [H]

Number of amino acids: Translated: 2136; Mature: 2136

Protein sequence:

>2136_residues
MNQFAADAADGLSAISEAFPLTAAQRDIWLDQLRQGNSPMYNIGGYVELTGPLDPALMQTALEGLVARHDAMRTSLLPGA
GEHGLPLQRFARSMPVPMPVHDLRSHPDPYAAARQLTQENIERLFTLDGGPLFRFSLLWLDDDRHWLSLQAHHLIVDGWG
FGEMLKSLDEIYNALALGQLPPDSAPSYVDFIRDDARYFQSARYARDRAYWLDKYQHRPEPLLLPRYQERFAGAAAPTRI
FSQVFPARLHERMKQVAREYGASAFHVLLAAIHVYFSRSAQRDEWVVGVPLLNRSGARFKSTLGLFTQVSAVRMGFGREL
SFKTLVKAIHDELKKDFRHQRFPLSEMNRALGLLREDRSQLFEVTVSYERDAHEYRYGEAQGRVVKVSNHEEGTPLSVHL
RSSRGDDEDSLYMVYNEAYFDANEVAALSGRLLWVLEQGLEEPALAVGDFSLSLPAESALLQQWNDTRVEFPQDLTIHQR
IEAQSAARPDAVAAESLGQQLTYAELNRQANALAHHLIGLGVRPDDRVALVARRGLDTLVALLAILKSGAGYVPVDPAHP
AERLSYLLRDSAPAVVLTQRDLRERLPVLDVSLIEIDSRGWPINDLNPDVSGLTSAHLAYVIYTSGSTGQPKGVMVEHHT
LSNLVDWHCTAFDLWAGRHASSLAGFGFDAMAWEVWPALCVGATLHLAPSRDGGEDIDALLDWWRAQPLDVSFLPTPIAE
YAFSRHVEHPTLRTLLIGGDRLRQFNREQTFAVINNYGPTEATVVATSGRIGPGRTLHIGKPVSNATAYLLDDRQRPVPI
GVAGELYVGGAGVARGYFNRPELTAERFLDDPFSRQPNARMYRTGDLARWRPDGTIEYLGRNDDQVKIRGVRIEPGEIEA
ALSRHESVRDAVVQVRDGQLLAWFTERQPLDITQLHAHLKTRLPSAMLPSAYVRLTALPLTANGKLDRQALPAPGPEALI
RREYEAPQGDVEILLAQIWAEVLQVEKVGRHDHFFELGGHSLLAVNLIERMRQLGMSSDVRVLFGQPTLAALAASVGTGR
EVEVPANRIPQGCTRITPDLLPLVELDQATLDRIIATVPGGAANVQDIYPLAPLQEGILYHHITAAPGDPYLLQSQLAFA
SVERVEAYAGALRQVMARHDILRTAVVWEGLTTPVQVVWREAELPVQEITFDPAEGDVLAQLHARFDARRYRIDVSQAPL
IRLMYARDPAHGRIVAILLFHHLALDHIALEVLRHEMRANLLGQGELLSPAVPYRNYVAQTRLGVSEQEHEAFFREMLAD
IDEPTLPFGLQDVQGDGRGIDEAVRTLAPELDRRLRLQARQAGVSVASLIHLAWAQVLAATSGQEHVVFGSVFMGRMQGG
EGADRALGVFINTLPLRVDMDRSAQEAVQLTHARLTDLLGHEHASLALAQRCSGVASPAPLFSALLNYRHTDLEAQESAS
DQAWQGIQTLDNEERTNYPMTLSVDDLGNALQITTRTLISIGARRIGDYVQTALQALVDTLEQAPQQPLNRLPILPAAEL
EQLLVEFNASEVDCPLDQPLQVLFEQQVQRRPDAIALQAGEQQLTYRQLNEQANRLAHHLREHGVQPDSRVAICVERSLD
LVVGLLGILKAGGAYVPLDPDYPLERLHYMLQDSAPVAVLVHDVTRNLLGDPGVPVIDFDRCTWQHASTENLQIPGLSAS
NLAYMIYTSGSTGTPKGVMIEHRSACNMVHWGSQISPPTEHGALLQKAPFSFDSSVWEIFWPLCSGLRLVLARPDGNRDS
AYVTRVIRERQITVVKFVPALLQQFIEQDDASQCTSLTDVLNGGGELTAALARRVRERLPWVRLHNVYGPTETTVDSTGW
TLEPDQPVPEAVVPIGKALSNTRLYVLDAHDQPVPFGVSGHLHIGGVGVARGYLGLSQMQAERFIDSPFVAGDRLYRTGD
LVRYRADGNLEFLGRNDFQIKLRGLRLEPGEIEARLIEHPAVREAVVLVRDERLVAYFTGREGFDAPPIETLRAHVLERL
PEYMAPGAYVKLDALPLTPNDKVDRKALPAPGAEAVLSRRYEAPEGEVEIRLAQIWAEVLQLEQVGRNDHFFELGGHSLL
AVSLVARMRQAGLHVDARTLFSQPTLAALAAQTSDQAKQLEVPPTTIPTLNRKRRL

Sequences:

>Translated_2136_residues
MNQFAADAADGLSAISEAFPLTAAQRDIWLDQLRQGNSPMYNIGGYVELTGPLDPALMQTALEGLVARHDAMRTSLLPGA
GEHGLPLQRFARSMPVPMPVHDLRSHPDPYAAARQLTQENIERLFTLDGGPLFRFSLLWLDDDRHWLSLQAHHLIVDGWG
FGEMLKSLDEIYNALALGQLPPDSAPSYVDFIRDDARYFQSARYARDRAYWLDKYQHRPEPLLLPRYQERFAGAAAPTRI
FSQVFPARLHERMKQVAREYGASAFHVLLAAIHVYFSRSAQRDEWVVGVPLLNRSGARFKSTLGLFTQVSAVRMGFGREL
SFKTLVKAIHDELKKDFRHQRFPLSEMNRALGLLREDRSQLFEVTVSYERDAHEYRYGEAQGRVVKVSNHEEGTPLSVHL
RSSRGDDEDSLYMVYNEAYFDANEVAALSGRLLWVLEQGLEEPALAVGDFSLSLPAESALLQQWNDTRVEFPQDLTIHQR
IEAQSAARPDAVAAESLGQQLTYAELNRQANALAHHLIGLGVRPDDRVALVARRGLDTLVALLAILKSGAGYVPVDPAHP
AERLSYLLRDSAPAVVLTQRDLRERLPVLDVSLIEIDSRGWPINDLNPDVSGLTSAHLAYVIYTSGSTGQPKGVMVEHHT
LSNLVDWHCTAFDLWAGRHASSLAGFGFDAMAWEVWPALCVGATLHLAPSRDGGEDIDALLDWWRAQPLDVSFLPTPIAE
YAFSRHVEHPTLRTLLIGGDRLRQFNREQTFAVINNYGPTEATVVATSGRIGPGRTLHIGKPVSNATAYLLDDRQRPVPI
GVAGELYVGGAGVARGYFNRPELTAERFLDDPFSRQPNARMYRTGDLARWRPDGTIEYLGRNDDQVKIRGVRIEPGEIEA
ALSRHESVRDAVVQVRDGQLLAWFTERQPLDITQLHAHLKTRLPSAMLPSAYVRLTALPLTANGKLDRQALPAPGPEALI
RREYEAPQGDVEILLAQIWAEVLQVEKVGRHDHFFELGGHSLLAVNLIERMRQLGMSSDVRVLFGQPTLAALAASVGTGR
EVEVPANRIPQGCTRITPDLLPLVELDQATLDRIIATVPGGAANVQDIYPLAPLQEGILYHHITAAPGDPYLLQSQLAFA
SVERVEAYAGALRQVMARHDILRTAVVWEGLTTPVQVVWREAELPVQEITFDPAEGDVLAQLHARFDARRYRIDVSQAPL
IRLMYARDPAHGRIVAILLFHHLALDHIALEVLRHEMRANLLGQGELLSPAVPYRNYVAQTRLGVSEQEHEAFFREMLAD
IDEPTLPFGLQDVQGDGRGIDEAVRTLAPELDRRLRLQARQAGVSVASLIHLAWAQVLAATSGQEHVVFGSVFMGRMQGG
EGADRALGVFINTLPLRVDMDRSAQEAVQLTHARLTDLLGHEHASLALAQRCSGVASPAPLFSALLNYRHTDLEAQESAS
DQAWQGIQTLDNEERTNYPMTLSVDDLGNALQITTRTLISIGARRIGDYVQTALQALVDTLEQAPQQPLNRLPILPAAEL
EQLLVEFNASEVDCPLDQPLQVLFEQQVQRRPDAIALQAGEQQLTYRQLNEQANRLAHHLREHGVQPDSRVAICVERSLD
LVVGLLGILKAGGAYVPLDPDYPLERLHYMLQDSAPVAVLVHDVTRNLLGDPGVPVIDFDRCTWQHASTENLQIPGLSAS
NLAYMIYTSGSTGTPKGVMIEHRSACNMVHWGSQISPPTEHGALLQKAPFSFDSSVWEIFWPLCSGLRLVLARPDGNRDS
AYVTRVIRERQITVVKFVPALLQQFIEQDDASQCTSLTDVLNGGGELTAALARRVRERLPWVRLHNVYGPTETTVDSTGW
TLEPDQPVPEAVVPIGKALSNTRLYVLDAHDQPVPFGVSGHLHIGGVGVARGYLGLSQMQAERFIDSPFVAGDRLYRTGD
LVRYRADGNLEFLGRNDFQIKLRGLRLEPGEIEARLIEHPAVREAVVLVRDERLVAYFTGREGFDAPPIETLRAHVLERL
PEYMAPGAYVKLDALPLTPNDKVDRKALPAPGAEAVLSRRYEAPEGEVEIRLAQIWAEVLQLEQVGRNDHFFELGGHSLL
AVSLVARMRQAGLHVDARTLFSQPTLAALAAQTSDQAKQLEVPPTTIPTLNRKRRL
>Mature_2136_residues
MNQFAADAADGLSAISEAFPLTAAQRDIWLDQLRQGNSPMYNIGGYVELTGPLDPALMQTALEGLVARHDAMRTSLLPGA
GEHGLPLQRFARSMPVPMPVHDLRSHPDPYAAARQLTQENIERLFTLDGGPLFRFSLLWLDDDRHWLSLQAHHLIVDGWG
FGEMLKSLDEIYNALALGQLPPDSAPSYVDFIRDDARYFQSARYARDRAYWLDKYQHRPEPLLLPRYQERFAGAAAPTRI
FSQVFPARLHERMKQVAREYGASAFHVLLAAIHVYFSRSAQRDEWVVGVPLLNRSGARFKSTLGLFTQVSAVRMGFGREL
SFKTLVKAIHDELKKDFRHQRFPLSEMNRALGLLREDRSQLFEVTVSYERDAHEYRYGEAQGRVVKVSNHEEGTPLSVHL
RSSRGDDEDSLYMVYNEAYFDANEVAALSGRLLWVLEQGLEEPALAVGDFSLSLPAESALLQQWNDTRVEFPQDLTIHQR
IEAQSAARPDAVAAESLGQQLTYAELNRQANALAHHLIGLGVRPDDRVALVARRGLDTLVALLAILKSGAGYVPVDPAHP
AERLSYLLRDSAPAVVLTQRDLRERLPVLDVSLIEIDSRGWPINDLNPDVSGLTSAHLAYVIYTSGSTGQPKGVMVEHHT
LSNLVDWHCTAFDLWAGRHASSLAGFGFDAMAWEVWPALCVGATLHLAPSRDGGEDIDALLDWWRAQPLDVSFLPTPIAE
YAFSRHVEHPTLRTLLIGGDRLRQFNREQTFAVINNYGPTEATVVATSGRIGPGRTLHIGKPVSNATAYLLDDRQRPVPI
GVAGELYVGGAGVARGYFNRPELTAERFLDDPFSRQPNARMYRTGDLARWRPDGTIEYLGRNDDQVKIRGVRIEPGEIEA
ALSRHESVRDAVVQVRDGQLLAWFTERQPLDITQLHAHLKTRLPSAMLPSAYVRLTALPLTANGKLDRQALPAPGPEALI
RREYEAPQGDVEILLAQIWAEVLQVEKVGRHDHFFELGGHSLLAVNLIERMRQLGMSSDVRVLFGQPTLAALAASVGTGR
EVEVPANRIPQGCTRITPDLLPLVELDQATLDRIIATVPGGAANVQDIYPLAPLQEGILYHHITAAPGDPYLLQSQLAFA
SVERVEAYAGALRQVMARHDILRTAVVWEGLTTPVQVVWREAELPVQEITFDPAEGDVLAQLHARFDARRYRIDVSQAPL
IRLMYARDPAHGRIVAILLFHHLALDHIALEVLRHEMRANLLGQGELLSPAVPYRNYVAQTRLGVSEQEHEAFFREMLAD
IDEPTLPFGLQDVQGDGRGIDEAVRTLAPELDRRLRLQARQAGVSVASLIHLAWAQVLAATSGQEHVVFGSVFMGRMQGG
EGADRALGVFINTLPLRVDMDRSAQEAVQLTHARLTDLLGHEHASLALAQRCSGVASPAPLFSALLNYRHTDLEAQESAS
DQAWQGIQTLDNEERTNYPMTLSVDDLGNALQITTRTLISIGARRIGDYVQTALQALVDTLEQAPQQPLNRLPILPAAEL
EQLLVEFNASEVDCPLDQPLQVLFEQQVQRRPDAIALQAGEQQLTYRQLNEQANRLAHHLREHGVQPDSRVAICVERSLD
LVVGLLGILKAGGAYVPLDPDYPLERLHYMLQDSAPVAVLVHDVTRNLLGDPGVPVIDFDRCTWQHASTENLQIPGLSAS
NLAYMIYTSGSTGTPKGVMIEHRSACNMVHWGSQISPPTEHGALLQKAPFSFDSSVWEIFWPLCSGLRLVLARPDGNRDS
AYVTRVIRERQITVVKFVPALLQQFIEQDDASQCTSLTDVLNGGGELTAALARRVRERLPWVRLHNVYGPTETTVDSTGW
TLEPDQPVPEAVVPIGKALSNTRLYVLDAHDQPVPFGVSGHLHIGGVGVARGYLGLSQMQAERFIDSPFVAGDRLYRTGD
LVRYRADGNLEFLGRNDFQIKLRGLRLEPGEIEARLIEHPAVREAVVLVRDERLVAYFTGREGFDAPPIETLRAHVLERL
PEYMAPGAYVKLDALPLTPNDKVDRKALPAPGAEAVLSRRYEAPEGEVEIRLAQIWAEVLQLEQVGRNDHFFELGGHSLL
AVSLVARMRQAGLHVDARTLFSQPTLAALAAQTSDQAKQLEVPPTTIPTLNRKRRL

Specific function: Incorporates six amino acids (for tyrocidine A, Asn, Gln, Tyr, Val, Orn, and Leu) in their L-configuration into the peptide product [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 6 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=601, Percent_Identity=24.9584026622296, Blast_Score=118, Evalue=5e-26,
Organism=Homo sapiens, GI28416953, Length=592, Percent_Identity=25.3378378378378, Blast_Score=104, Evalue=8e-22,
Organism=Homo sapiens, GI38505220, Length=515, Percent_Identity=25.0485436893204, Blast_Score=96, Evalue=5e-19,
Organism=Homo sapiens, GI156151445, Length=539, Percent_Identity=23.191094619666, Blast_Score=82, Evalue=7e-15,
Organism=Homo sapiens, GI115511026, Length=489, Percent_Identity=24.7443762781186, Blast_Score=79, Evalue=5e-14,
Organism=Homo sapiens, GI157311624, Length=511, Percent_Identity=25.2446183953033, Blast_Score=79, Evalue=7e-14,
Organism=Homo sapiens, GI157311622, Length=511, Percent_Identity=25.2446183953033, Blast_Score=79, Evalue=7e-14,
Organism=Homo sapiens, GI58082049, Length=511, Percent_Identity=25.2446183953033, Blast_Score=78, Evalue=1e-13,
Organism=Escherichia coli, GI1786801, Length=1069, Percent_Identity=30.1216089803555, Blast_Score=373, Evalue=1e-104,
Organism=Escherichia coli, GI1786810, Length=506, Percent_Identity=27.0750988142292, Blast_Score=123, Evalue=2e-28,
Organism=Escherichia coli, GI145693145, Length=518, Percent_Identity=26.0617760617761, Blast_Score=109, Evalue=2e-24,
Organism=Escherichia coli, GI1788107, Length=542, Percent_Identity=25.2767527675277, Blast_Score=97, Evalue=1e-20,
Organism=Escherichia coli, GI1790505, Length=536, Percent_Identity=22.7611940298507, Blast_Score=83, Evalue=2e-16,
Organism=Escherichia coli, GI221142682, Length=508, Percent_Identity=22.8346456692913, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17556356, Length=562, Percent_Identity=26.6903914590747, Blast_Score=148, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI17550940, Length=459, Percent_Identity=23.9651416122004, Blast_Score=120, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI32564422, Length=417, Percent_Identity=26.1390887290168, Blast_Score=89, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI32564420, Length=415, Percent_Identity=25.7831325301205, Blast_Score=87, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17538037, Length=528, Percent_Identity=24.6212121212121, Blast_Score=87, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17557194, Length=544, Percent_Identity=23.8970588235294, Blast_Score=85, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17560140, Length=518, Percent_Identity=23.1660231660232, Blast_Score=77, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71994703, Length=209, Percent_Identity=30.622009569378, Blast_Score=74, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71994694, Length=209, Percent_Identity=30.622009569378, Blast_Score=74, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI71994690, Length=209, Percent_Identity=30.622009569378, Blast_Score=74, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319591, Length=854, Percent_Identity=25.175644028103, Blast_Score=224, Evalue=2e-58,
Organism=Saccharomyces cerevisiae, GI6319699, Length=219, Percent_Identity=27.8538812785388, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24648676, Length=650, Percent_Identity=31.3846153846154, Blast_Score=233, Evalue=1e-60,
Organism=Drosophila melanogaster, GI24581924, Length=516, Percent_Identity=25, Blast_Score=107, Evalue=8e-23,
Organism=Drosophila melanogaster, GI19922652, Length=506, Percent_Identity=23.9130434782609, Blast_Score=94, Evalue=1e-18,
Organism=Drosophila melanogaster, GI18859661, Length=522, Percent_Identity=25.095785440613, Blast_Score=93, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21355181, Length=491, Percent_Identity=20.5702647657841, Blast_Score=75, Evalue=4e-13,
Organism=Drosophila melanogaster, GI62472339, Length=376, Percent_Identity=25.531914893617, Blast_Score=72, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24667955, Length=376, Percent_Identity=25.531914893617, Blast_Score=72, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24667959, Length=376, Percent_Identity=25.531914893617, Blast_Score=71, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding; PF00975 Thioesterase [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 236992; Mature: 236992

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQFAADAADGLSAISEAFPLTAAQRDIWLDQLRQGNSPMYNIGGYVELTGPLDPALMQT
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEECCCEEEECCCCCHHHHHH
ALEGLVARHDAMRTSLLPGAGEHGLPLQRFARSMPVPMPVHDLRSHPDPYAAARQLTQEN
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHHH
IERLFTLDGGPLFRFSLLWLDDDRHWLSLQAHHLIVDGWGFGEMLKSLDEIYNALALGQL
HHHEEECCCCCEEEEEEEEEECCCCEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHCCCC
PPDSAPSYVDFIRDDARYFQSARYARDRAYWLDKYQHRPEPLLLPRYQERFAGAAAPTRI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCHHHHH
FSQVFPARLHERMKQVAREYGASAFHVLLAAIHVYFSRSAQRDEWVVGVPLLNRSGARFK
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEECEECCCCCHHH
STLGLFTQVSAVRMGFGRELSFKTLVKAIHDELKKDFRHQRFPLSEMNRALGLLREDRSQ
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
LFEVTVSYERDAHEYRYGEAQGRVVKVSNHEEGTPLSVHLRSSRGDDEDSLYMVYNEAYF
HEEEEEECCCCHHHHCCCCCCCCEEEECCCCCCCCEEEEEECCCCCCCCCEEEEEECCCC
DANEVAALSGRLLWVLEQGLEEPALAVGDFSLSLPAESALLQQWNDTRVEFPQDLTIHQR
CHHHHHHHCCHHHHHHHHCCCCCCEEECCEEECCCHHHHHHHCCCCCCCCCCCCCHHHHH
IEAQSAARPDAVAAESLGQQLTYAELNRQANALAHHLIGLGVRPDDRVALVARRGLDTLV
HHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHCCHHHHH
ALLAILKSGAGYVPVDPAHPAERLSYLLRDSAPAVVLTQRDLRERLPVLDVSLIEIDSRG
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEHHHHHHHCCEEEEEEEEECCCC
WPINDLNPDVSGLTSAHLAYVIYTSGSTGQPKGVMVEHHTLSNLVDWHCTAFDLWAGRHA
CCCCCCCCCHHHHHCCEEEEEEEECCCCCCCCCEEEECHHHHHHHHHCCEEEEHHCCCCH
SSLAGFGFDAMAWEVWPALCVGATLHLAPSRDGGEDIDALLDWWRAQPLDVSFLPTPIAE
HHHHCCCCHHHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHCCCCCCEECCCCHHHH
YAFSRHVEHPTLRTLLIGGDRLRQFNREQTFAVINNYGPTEATVVATSGRIGPGRTLHIG
HHHHHCCCCCCCEEEEECCHHHHHCCCCCEEEEEECCCCCCEEEEEECCCCCCCCEEEEC
KPVSNATAYLLDDRQRPVPIGVAGELYVGGAGVARGYFNRPELTAERFLDDPFSRQPNAR
CCCCCCEEEEECCCCCCCEEECCCEEEECCCHHHCCCCCCCCHHHHHHCCCCCCCCCCCC
MYRTGDLARWRPDGTIEYLGRNDDQVKIRGVRIEPGEIEAALSRHESVRDAVVQVRDGQL
EEECCCCCEECCCCCEEECCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHEECCCCE
LAWFTERQPLDITQLHAHLKTRLPSAMLPSAYVRLTALPLTANGKLDRQALPAPGPEALI
EEEECCCCCCCHHHHHHHHHHHCCHHHCCCCEEEEEEEEEECCCCCCCCCCCCCCHHHHH
RREYEAPQGDVEILLAQIWAEVLQVEKVGRHDHFFELGGHSLLAVNLIERMRQLGMSSDV
HHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHCCCCCCC
RVLFGQPTLAALAASVGTGREVEVPANRIPQGCTRITPDLLPLVELDQATLDRIIATVPG
EEEECCCHHHHHHHHCCCCCEEECCHHHCCCCHHHCCCHHHHHHHCCHHHHHHHHHHCCC
GAANVQDIYPLAPLQEGILYHHITAAPGDPYLLQSQLAFASVERVEAYAGALRQVMARHD
CCCCCCCCCCCCCHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILRTAVVWEGLTTPVQVVWREAELPVQEITFDPAEGDVLAQLHARFDARRYRIDVSQAPL
HHHHHHHHCCCCCHHHHHHHHCCCCHHHEECCCCCCHHHHHHHHHHCCHHEEEECCCCCE
IRLMYARDPAHGRIVAILLFHHLALDHIALEVLRHEMRANLLGQGELLSPAVPYRNYVAQ
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
TRLGVSEQEHEAFFREMLADIDEPTLPFGLQDVQGDGRGIDEAVRTLAPELDRRLRLQAR
HHCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
QAGVSVASLIHLAWAQVLAATSGQEHVVFGSVFMGRMQGGEGADRALGVFINTLPLRVDM
HHCHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHCCCCCCCHHHHHHHHEEEEEEEEC
DRSAQEAVQLTHARLTDLLGHEHASLALAQRCSGVASPAPLFSALLNYRHTDLEAQESAS
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHCCC
DQAWQGIQTLDNEERTNYPMTLSVDDLGNALQITTRTLISIGARRIGDYVQTALQALVDT
HHHHHHHHHCCCCCCCCCCEEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEQAPQQPLNRLPILPAAELEQLLVEFNASEVDCPLDQPLQVLFEQQVQRRPDAIALQAG
HHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCC
EQQLTYRQLNEQANRLAHHLREHGVQPDSRVAICVERSLDLVVGLLGILKAGGAYVPLDP
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCEECCCC
DYPLERLHYMLQDSAPVAVLVHDVTRNLLGDPGVPVIDFDRCTWQHASTENLQIPGLSAS
CCCHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCEECCCCCCC
NLAYMIYTSGSTGTPKGVMIEHRSACNMVHWGSQISPPTEHGALLQKAPFSFDSSVWEIF
CEEEEEEECCCCCCCCCEEEECCCCCCEEECCCCCCCCCHHCCHHHCCCCCCCCHHHHHH
WPLCSGLRLVLARPDGNRDSAYVTRVIRERQITVVKFVPALLQQFIEQDDASQCTSLTDV
HHHHCCCEEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LNGGGELTAALARRVRERLPWVRLHNVYGPTETTVDSTGWTLEPDQPVPEAVVPIGKALS
HCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHC
NTRLYVLDAHDQPVPFGVSGHLHIGGVGVARGYLGLSQMQAERFIDSPFVAGDRLYRTGD
CCEEEEEECCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCC
LVRYRADGNLEFLGRNDFQIKLRGLRLEPGEIEARLIEHPAVREAVVLVRDERLVAYFTG
EEEEECCCCEEEECCCCEEEEEEEEECCCCCHHHHHHCCCHHHHEEEEEECCEEEEEEEC
REGFDAPPIETLRAHVLERLPEYMAPGAYVKLDALPLTPNDKVDRKALPAPGAEAVLSRR
CCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHC
YEAPEGEVEIRLAQIWAEVLQLEQVGRNDHFFELGGHSLLAVSLVARMRQAGLHVDARTL
CCCCCCCEEEHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCHHHH
FSQPTLAALAAQTSDQAKQLEVPPTTIPTLNRKRRL
HCCCHHHHHHHHCCCHHHEECCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNQFAADAADGLSAISEAFPLTAAQRDIWLDQLRQGNSPMYNIGGYVELTGPLDPALMQT
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEECCCEEEECCCCCHHHHHH
ALEGLVARHDAMRTSLLPGAGEHGLPLQRFARSMPVPMPVHDLRSHPDPYAAARQLTQEN
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHHH
IERLFTLDGGPLFRFSLLWLDDDRHWLSLQAHHLIVDGWGFGEMLKSLDEIYNALALGQL
HHHEEECCCCCEEEEEEEEEECCCCEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHCCCC
PPDSAPSYVDFIRDDARYFQSARYARDRAYWLDKYQHRPEPLLLPRYQERFAGAAAPTRI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCHHHHH
FSQVFPARLHERMKQVAREYGASAFHVLLAAIHVYFSRSAQRDEWVVGVPLLNRSGARFK
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEECEECCCCCHHH
STLGLFTQVSAVRMGFGRELSFKTLVKAIHDELKKDFRHQRFPLSEMNRALGLLREDRSQ
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
LFEVTVSYERDAHEYRYGEAQGRVVKVSNHEEGTPLSVHLRSSRGDDEDSLYMVYNEAYF
HEEEEEECCCCHHHHCCCCCCCCEEEECCCCCCCCEEEEEECCCCCCCCCEEEEEECCCC
DANEVAALSGRLLWVLEQGLEEPALAVGDFSLSLPAESALLQQWNDTRVEFPQDLTIHQR
CHHHHHHHCCHHHHHHHHCCCCCCEEECCEEECCCHHHHHHHCCCCCCCCCCCCCHHHHH
IEAQSAARPDAVAAESLGQQLTYAELNRQANALAHHLIGLGVRPDDRVALVARRGLDTLV
HHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHCCHHHHH
ALLAILKSGAGYVPVDPAHPAERLSYLLRDSAPAVVLTQRDLRERLPVLDVSLIEIDSRG
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEHHHHHHHCCEEEEEEEEECCCC
WPINDLNPDVSGLTSAHLAYVIYTSGSTGQPKGVMVEHHTLSNLVDWHCTAFDLWAGRHA
CCCCCCCCCHHHHHCCEEEEEEEECCCCCCCCCEEEECHHHHHHHHHCCEEEEHHCCCCH
SSLAGFGFDAMAWEVWPALCVGATLHLAPSRDGGEDIDALLDWWRAQPLDVSFLPTPIAE
HHHHCCCCHHHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHCCCCCCEECCCCHHHH
YAFSRHVEHPTLRTLLIGGDRLRQFNREQTFAVINNYGPTEATVVATSGRIGPGRTLHIG
HHHHHCCCCCCCEEEEECCHHHHHCCCCCEEEEEECCCCCCEEEEEECCCCCCCCEEEEC
KPVSNATAYLLDDRQRPVPIGVAGELYVGGAGVARGYFNRPELTAERFLDDPFSRQPNAR
CCCCCCEEEEECCCCCCCEEECCCEEEECCCHHHCCCCCCCCHHHHHHCCCCCCCCCCCC
MYRTGDLARWRPDGTIEYLGRNDDQVKIRGVRIEPGEIEAALSRHESVRDAVVQVRDGQL
EEECCCCCEECCCCCEEECCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHEECCCCE
LAWFTERQPLDITQLHAHLKTRLPSAMLPSAYVRLTALPLTANGKLDRQALPAPGPEALI
EEEECCCCCCCHHHHHHHHHHHCCHHHCCCCEEEEEEEEEECCCCCCCCCCCCCCHHHHH
RREYEAPQGDVEILLAQIWAEVLQVEKVGRHDHFFELGGHSLLAVNLIERMRQLGMSSDV
HHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHCCCCCCC
RVLFGQPTLAALAASVGTGREVEVPANRIPQGCTRITPDLLPLVELDQATLDRIIATVPG
EEEECCCHHHHHHHHCCCCCEEECCHHHCCCCHHHCCCHHHHHHHCCHHHHHHHHHHCCC
GAANVQDIYPLAPLQEGILYHHITAAPGDPYLLQSQLAFASVERVEAYAGALRQVMARHD
CCCCCCCCCCCCCHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILRTAVVWEGLTTPVQVVWREAELPVQEITFDPAEGDVLAQLHARFDARRYRIDVSQAPL
HHHHHHHHCCCCCHHHHHHHHCCCCHHHEECCCCCCHHHHHHHHHHCCHHEEEECCCCCE
IRLMYARDPAHGRIVAILLFHHLALDHIALEVLRHEMRANLLGQGELLSPAVPYRNYVAQ
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
TRLGVSEQEHEAFFREMLADIDEPTLPFGLQDVQGDGRGIDEAVRTLAPELDRRLRLQAR
HHCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
QAGVSVASLIHLAWAQVLAATSGQEHVVFGSVFMGRMQGGEGADRALGVFINTLPLRVDM
HHCHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHCCCCCCCHHHHHHHHEEEEEEEEC
DRSAQEAVQLTHARLTDLLGHEHASLALAQRCSGVASPAPLFSALLNYRHTDLEAQESAS
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHCCC
DQAWQGIQTLDNEERTNYPMTLSVDDLGNALQITTRTLISIGARRIGDYVQTALQALVDT
HHHHHHHHHCCCCCCCCCCEEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEQAPQQPLNRLPILPAAELEQLLVEFNASEVDCPLDQPLQVLFEQQVQRRPDAIALQAG
HHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCC
EQQLTYRQLNEQANRLAHHLREHGVQPDSRVAICVERSLDLVVGLLGILKAGGAYVPLDP
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCEECCCC
DYPLERLHYMLQDSAPVAVLVHDVTRNLLGDPGVPVIDFDRCTWQHASTENLQIPGLSAS
CCCHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCEECCCCCCC
NLAYMIYTSGSTGTPKGVMIEHRSACNMVHWGSQISPPTEHGALLQKAPFSFDSSVWEIF
CEEEEEEECCCCCCCCCEEEECCCCCCEEECCCCCCCCCHHCCHHHCCCCCCCCHHHHHH
WPLCSGLRLVLARPDGNRDSAYVTRVIRERQITVVKFVPALLQQFIEQDDASQCTSLTDV
HHHHCCCEEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LNGGGELTAALARRVRERLPWVRLHNVYGPTETTVDSTGWTLEPDQPVPEAVVPIGKALS
HCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHC
NTRLYVLDAHDQPVPFGVSGHLHIGGVGVARGYLGLSQMQAERFIDSPFVAGDRLYRTGD
CCEEEEEECCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCC
LVRYRADGNLEFLGRNDFQIKLRGLRLEPGEIEARLIEHPAVREAVVLVRDERLVAYFTG
EEEEECCCCEEEECCCCEEEEEEEEECCCCCHHHHHHCCCHHHHEEEEEECCEEEEEEEC
REGFDAPPIETLRAHVLERLPEYMAPGAYVKLDALPLTPNDKVDRKALPAPGAEAVLSRR
CCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHC
YEAPEGEVEIRLAQIWAEVLQLEQVGRNDHFFELGGHSLLAVSLVARMRQAGLHVDARTL
CCCCCCCEEEHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCHHHH
FSQPTLAALAAQTSDQAKQLEVPPTTIPTLNRKRRL
HCCCHHHHHHHHCCCHHHEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9352938; 10801488 [H]