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The map label for this gene is glpG [H]

Identifier: 77458424

GI number: 77458424

Start: 2480667

End: 2481536

Strand: Direct

Name: glpG [H]

Synonym: Pfl01_2197

Alternate gene names: 77458424

Gene position: 2480667-2481536 (Clockwise)

Preceding gene: 77458423

Following gene: 77458425

Centisome position: 38.53

GC content: 63.33

Gene sequence:

>870_bases
ATGAGTGCCATAGCCGTCTTGCGTGTGCCGTTGGCGGCGGACCTGAGTGGTTTCGTCAAACTGCTGCAACGCATGCAAGT
GCCCCATCGCGTCAGCGAAGAGGCGGGCGAGCAGGTGTTGTGGGTGCCGTCGGAAATCAGCGATGACGTACGCTCGCTGT
ACGAGCGTTTCCCGGCGGGTGACCCGGATCAGCAGCTGGAAATTCCGTCGGCGCCGACGCTCAAGCGCCCGAGCTTCGCC
GAGCAACTGAAACGTGCCAAAGCCACCGGATTCATTCTGCTGCTGAGCCTGATCGTCGGCGGGTTGACCTTCCTTGGCGA
TAACCTCGACACCATGCGTTGGCTGACCTTCCTCGATTTCCGCGTGGTCGGCGACTACATCCACTTCACACCACTGGCCG
ACAGCCTGGCAGCGGGGCAGTGGTGGCGCCTGTTTACGCCGATGCTGATCCACTTCGGCGTCCTGCACCTGGCCATGAAC
GGCATGTGGTACTGGGAACTGGGGCGGCGCATCGAGTCGCGCCAGGGCAGCGTCAACCTGATCGGCCTGACGCTGCTGTT
CGGCCTGGTTTCCAACTATGCGCAGTTCGCGTGGGGCGGCCCGAGCCTGTTCGGTGGCCTGTCCGGCGTACTTTACGGGC
TGCTCGGTCACTGCTGGATCTTCCAGCTGCTGGCGCCGAACCCGGCCTATCGCCTGCCGCGCGGCGTGCTGGCGATGATG
CTGGTGTGGTTGCTGGTGTGCATGTCGGGGCTGGTCTCGATGATCGGTTTCGGCGAAATCGCCAACGCCGCCCACGTCGG
CGGGTTACTCATCGGATGCTTCACCGGTTTGTTGGGCGGTTTGTACAACCGCCGTAAACTGGCCGCCTGA

Upstream 100 bases:

>100_bases
TGCTGTACGGCAAACTGGTGGCCTATCGTCTGGATCAGGAAACCCGCCTCGATCCGCATAAATTTGTCTGGGTCGACGTC
GAGCGGCCGGAGGTGCTGCG

Downstream 100 bases:

>100_bases
ATTTTTTGAATAAAGAGCACGGAGACCCTGATGTCCTCTTTTAACGATTTGATCAAGAACATCACCCCCGACATCTACCA
GAGCCTGAAACTGGCGGTAG

Product: rhomboid-like protein

Products: NA

Alternate protein names: Intramembrane serine protease [H]

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MSAIAVLRVPLAADLSGFVKLLQRMQVPHRVSEEAGEQVLWVPSEISDDVRSLYERFPAGDPDQQLEIPSAPTLKRPSFA
EQLKRAKATGFILLLSLIVGGLTFLGDNLDTMRWLTFLDFRVVGDYIHFTPLADSLAAGQWWRLFTPMLIHFGVLHLAMN
GMWYWELGRRIESRQGSVNLIGLTLLFGLVSNYAQFAWGGPSLFGGLSGVLYGLLGHCWIFQLLAPNPAYRLPRGVLAMM
LVWLLVCMSGLVSMIGFGEIANAAHVGGLLIGCFTGLLGGLYNRRKLAA

Sequences:

>Translated_289_residues
MSAIAVLRVPLAADLSGFVKLLQRMQVPHRVSEEAGEQVLWVPSEISDDVRSLYERFPAGDPDQQLEIPSAPTLKRPSFA
EQLKRAKATGFILLLSLIVGGLTFLGDNLDTMRWLTFLDFRVVGDYIHFTPLADSLAAGQWWRLFTPMLIHFGVLHLAMN
GMWYWELGRRIESRQGSVNLIGLTLLFGLVSNYAQFAWGGPSLFGGLSGVLYGLLGHCWIFQLLAPNPAYRLPRGVLAMM
LVWLLVCMSGLVSMIGFGEIANAAHVGGLLIGCFTGLLGGLYNRRKLAA
>Mature_288_residues
SAIAVLRVPLAADLSGFVKLLQRMQVPHRVSEEAGEQVLWVPSEISDDVRSLYERFPAGDPDQQLEIPSAPTLKRPSFAE
QLKRAKATGFILLLSLIVGGLTFLGDNLDTMRWLTFLDFRVVGDYIHFTPLADSLAAGQWWRLFTPMLIHFGVLHLAMNG
MWYWELGRRIESRQGSVNLIGLTLLFGLVSNYAQFAWGGPSLFGGLSGVLYGLLGHCWIFQLLAPNPAYRLPRGVLAMML
VWLLVCMSGLVSMIGFGEIANAAHVGGLLIGCFTGLLGGLYNRRKLAA

Specific function: Rhomboid-type serine protease that catalyzes intramembrane proteolysis [H]

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S54 family [H]

Homologues:

Organism=Escherichia coli, GI48994938, Length=266, Percent_Identity=29.6992481203008, Blast_Score=105, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022732
- InterPro:   IPR002610
- InterPro:   IPR022764 [H]

Pfam domain/function: PF12122 DUF3582; PF01694 Rhomboid [H]

EC number: =3.4.21.105 [H]

Molecular weight: Translated: 31847; Mature: 31716

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAIAVLRVPLAADLSGFVKLLQRMQVPHRVSEEAGEQVLWVPSEISDDVRSLYERFPAG
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCEEEECCHHHHHHHHHHHHHCCCC
DPDQQLEIPSAPTLKRPSFAEQLKRAKATGFILLLSLIVGGLTFLGDNLDTMRWLTFLDF
CCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
RVVGDYIHFTPLADSLAAGQWWRLFTPMLIHFGVLHLAMNGMWYWELGRRIESRQGSVNL
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHH
IGLTLLFGLVSNYAQFAWGGPSLFGGLSGVLYGLLGHCWIFQLLAPNPAYRLPRGVLAMM
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHH
LVWLLVCMSGLVSMIGFGEIANAAHVGGLLIGCFTGLLGGLYNRRKLAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SAIAVLRVPLAADLSGFVKLLQRMQVPHRVSEEAGEQVLWVPSEISDDVRSLYERFPAG
CCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCEEEECCHHHHHHHHHHHHHCCCC
DPDQQLEIPSAPTLKRPSFAEQLKRAKATGFILLLSLIVGGLTFLGDNLDTMRWLTFLDF
CCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
RVVGDYIHFTPLADSLAAGQWWRLFTPMLIHFGVLHLAMNGMWYWELGRRIESRQGSVNL
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHH
IGLTLLFGLVSNYAQFAWGGPSLFGGLSGVLYGLLGHCWIFQLLAPNPAYRLPRGVLAMM
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHH
LVWLLVCMSGLVSMIGFGEIANAAHVGGLLIGCFTGLLGGLYNRRKLAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA