Click here to switch to the map view.

The map label for this gene is moaE [H]

Identifier: 77458372

GI number: 77458372

Start: 2429986

End: 2430447

Strand: Reverse

Name: moaE [H]

Synonym: Pfl01_2145

Alternate gene names: 77458372

Gene position: 2430447-2429986 (Counterclockwise)

Preceding gene: 77458373

Following gene: 77458371

Centisome position: 37.75

GC content: 60.82

Gene sequence:

>462_bases
ATGGGTGTTCGAGTCCAGCGTAAAGGCTTCGATGCCGGTCAGTTGATTGCCGACCTGCATGCGCGCAATCCACGGGTGGG
CGCGGTGGTGAATTTCATTGGTTATGTGCGGGATCTGAACGTCGGGCAGTCGGTGACCGAGCTGTTTCTGGAGCACTATC
CGGGCATGACCGAGAAGGCTCTGGAGCAGATAGCCGAACAGGCTCGCGAGCGCTGGCCGTTGCTGGCGGTGGAGATTGTG
CATCGGGTCGGTGCGTTGTCGGTGACCGAACCGATCGTGTTTGTTGGCGTCAGCAGCAAGCATCGGCATGCGGCGTTCCA
GGCCTGTGCGTTCATCATGGATGTGCTGAAGACCCACGCGCCGTTCTGGAAACGTGAGACCACGCCAGAGGGTTCGCATT
GGGTCGAGGCGCGGGAGAGTGATCGGAATGCGGCGTTTCGCTGGAGTCTGGCGCATGCCTGA

Upstream 100 bases:

>100_bases
CCTGATGTGCGCGGTGAATCAGGAGCTGTGTCAGCCGGATCAGGCCATTGAGGACTTCGACGAGATTGCGTTTTTCCCGC
CGGTCACGGGGGGTTGAGAC

Downstream 100 bases:

>100_bases
CCGGGTACTGTCGAATGCGACAAAAGCCTGATTAGATAGCAGCTCCCGCCGATTCGAACGTGGAGCCACACTTGAGCCAA
ACACCAAAGGATTTGCATCG

Product: molybdopterin synthase subunit MoaE

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 153; Mature: 152

Protein sequence:

>153_residues
MGVRVQRKGFDAGQLIADLHARNPRVGAVVNFIGYVRDLNVGQSVTELFLEHYPGMTEKALEQIAEQARERWPLLAVEIV
HRVGALSVTEPIVFVGVSSKHRHAAFQACAFIMDVLKTHAPFWKRETTPEGSHWVEARESDRNAAFRWSLAHA

Sequences:

>Translated_153_residues
MGVRVQRKGFDAGQLIADLHARNPRVGAVVNFIGYVRDLNVGQSVTELFLEHYPGMTEKALEQIAEQARERWPLLAVEIV
HRVGALSVTEPIVFVGVSSKHRHAAFQACAFIMDVLKTHAPFWKRETTPEGSHWVEARESDRNAAFRWSLAHA
>Mature_152_residues
GVRVQRKGFDAGQLIADLHARNPRVGAVVNFIGYVRDLNVGQSVTELFLEHYPGMTEKALEQIAEQARERWPLLAVEIVH
RVGALSVTEPIVFVGVSSKHRHAAFQACAFIMDVLKTHAPFWKRETTPEGSHWVEARESDRNAAFRWSLAHA

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=129, Percent_Identity=33.3333333333333, Blast_Score=87, Evalue=8e-18,
Organism=Escherichia coli, GI1787003, Length=122, Percent_Identity=64.7540983606557, Blast_Score=164, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI17509279, Length=117, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21356259, Length=132, Percent_Identity=36.3636363636364, Blast_Score=77, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 17211; Mature: 17080

Theoretical pI: Translated: 8.54; Mature: 8.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVRVQRKGFDAGQLIADLHARNPRVGAVVNFIGYVRDLNVGQSVTELFLEHYPGMTEKA
CCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHH
LEQIAEQARERWPLLAVEIVHRVGALSVTEPIVFVGVSSKHRHAAFQACAFIMDVLKTHA
HHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCC
PFWKRETTPEGSHWVEARESDRNAAFRWSLAHA
CCCCCCCCCCCCHHHHCCCCCCCCEEEEECCCC
>Mature Secondary Structure 
GVRVQRKGFDAGQLIADLHARNPRVGAVVNFIGYVRDLNVGQSVTELFLEHYPGMTEKA
CCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHH
LEQIAEQARERWPLLAVEIVHRVGALSVTEPIVFVGVSSKHRHAAFQACAFIMDVLKTHA
HHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCC
PFWKRETTPEGSHWVEARESDRNAAFRWSLAHA
CCCCCCCCCCCCHHHHCCCCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]