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The map label for this gene is udg [H]

Identifier: 77458251

GI number: 77458251

Start: 2307302

End: 2308654

Strand: Reverse

Name: udg [H]

Synonym: Pfl01_2024

Alternate gene names: 77458251

Gene position: 2308654-2307302 (Counterclockwise)

Preceding gene: 77458260

Following gene: 77458250

Centisome position: 35.86

GC content: 61.2

Gene sequence:

>1353_bases
ATGGACGTGAGCGTATTTGGTACGGGCTATGTTGGCCTGATACAAGCAGCCGCACTTGCCGATGTCGGACATCGCGTATT
GTGCGTCGATATTGACCCGAACAAGATTAAACAACTGCAACAGGCAGTACCGCCTATTAGCGAACCGGGTCTTTCGGCAA
CTTTGGAAGAAAACATCAAGGCCGGGCGTTTGTTGTTCAGCACCCAGGCCAGCGATGCGGTGGAACATGCCGGACTGATC
TTCATCGCCGTGGGCACGCCGGCCGACGAAGACGGCTCCGCCGACCTCAGCCATGTGCTCAACGTGGCGCGGCAGATCGC
AAGCTGCATGGAGGACGATCGGACGCTGATCATCAAATCCACGGTGCCGGTCGGCACGGCGGATCAGGTGCTGCACACCG
CTGAAGAAGAACTGCAGCGTCGCGGCAAAAACGGTCTGGCGGTGCGGGTGGTGTCCAACCCCGAGTTTCTCAAGGAAGGC
AGCGCCCTCGCCGACTGCATGCGTCCGGACAGGATCATTGTCGGCACTCTGGACCCTGAAGCCCGGGAGCAGATGAGCGA
GCTGTACGCACCGTTCTGCCGCAACCACGAAAAACTGATGTTCATGGACAACCGCAGCGCCGAGCTGACCAAGTACGCGG
CCAACGCGATGCTCGCCACCCGCATCAGCTTCATGAACGAGCTGGCCAACCTCACCGAACTGCTCGGCGCCGACATCGAA
GCGGTGCGCAAAGGCATCGGCTCCGATCCGCGCATCGGCTATCACTTCATCTACCCGGGCTGCGGCTTCGGTGGCTCGTG
CTTTCCCAAGGACCTGCGCGCCCTGCTGCACACCGCTGAACACAACGGCATGCCGCTGAAACTGCTGCGCAGCGTCACCG
ACGTCAACGACGCGCAACGGCACATCCTGTTCAGCAAACTCAGGGCGCAATTTCCTCAAGGCCTGGCCGGCAAGTCCATC
GCGATCTGGGGCCTGGCGTTCAAGCCGAATACCGATGACATGCGTGAAGCCCCGAGTCGTTACCTGATGGAAGCGCTGTG
GGCCGAAGGCGCCAGCGTGCAGGCCTACGATCCGGAAGCGATGTCCGAGTGCCGGCGCATTTACGGTTACCGCAACGACC
TGCACCTGTGTGCCACCCGCGACGACACCCTGGAAGATGCCGATGCACTAGTGATCTGCACCGAGTGGAAAAACTTTCGT
GTGGTGGACTTTGAACTGCTCGCCGAGAAGCTGCGCGCGAAGGTCATCGTCGACGGGCGCAACCTTTACAACCCGGAACA
AGTGGCGGCCGCCGGCCTGCATTACAGCGGTATCGGTCTGCGCCACATCGCGCCCGACGAGGGGCGACCATGA

Upstream 100 bases:

>100_bases
CAACATGTCATTTTGCTGACACGCTTTCCCCACGCTGCGCTATACCCCTTTTGACAGTTCATTTTCGATCTTCCATCACC
GTCTTACGAGGCACGCCAAT

Downstream 100 bases:

>100_bases
ACTTCCTGTTACCCACTGCCTATCGCCCACGCGCCGCTCGCGGCTGACCACCAGCGGAGGACTCCATGACTGGACATGAG
AAAGGTGTACCGATCCAACA

Product: UDP-glucose/GDP-mannose dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MDVSVFGTGYVGLIQAAALADVGHRVLCVDIDPNKIKQLQQAVPPISEPGLSATLEENIKAGRLLFSTQASDAVEHAGLI
FIAVGTPADEDGSADLSHVLNVARQIASCMEDDRTLIIKSTVPVGTADQVLHTAEEELQRRGKNGLAVRVVSNPEFLKEG
SALADCMRPDRIIVGTLDPEAREQMSELYAPFCRNHEKLMFMDNRSAELTKYAANAMLATRISFMNELANLTELLGADIE
AVRKGIGSDPRIGYHFIYPGCGFGGSCFPKDLRALLHTAEHNGMPLKLLRSVTDVNDAQRHILFSKLRAQFPQGLAGKSI
AIWGLAFKPNTDDMREAPSRYLMEALWAEGASVQAYDPEAMSECRRIYGYRNDLHLCATRDDTLEDADALVICTEWKNFR
VVDFELLAEKLRAKVIVDGRNLYNPEQVAAAGLHYSGIGLRHIAPDEGRP

Sequences:

>Translated_450_residues
MDVSVFGTGYVGLIQAAALADVGHRVLCVDIDPNKIKQLQQAVPPISEPGLSATLEENIKAGRLLFSTQASDAVEHAGLI
FIAVGTPADEDGSADLSHVLNVARQIASCMEDDRTLIIKSTVPVGTADQVLHTAEEELQRRGKNGLAVRVVSNPEFLKEG
SALADCMRPDRIIVGTLDPEAREQMSELYAPFCRNHEKLMFMDNRSAELTKYAANAMLATRISFMNELANLTELLGADIE
AVRKGIGSDPRIGYHFIYPGCGFGGSCFPKDLRALLHTAEHNGMPLKLLRSVTDVNDAQRHILFSKLRAQFPQGLAGKSI
AIWGLAFKPNTDDMREAPSRYLMEALWAEGASVQAYDPEAMSECRRIYGYRNDLHLCATRDDTLEDADALVICTEWKNFR
VVDFELLAEKLRAKVIVDGRNLYNPEQVAAAGLHYSGIGLRHIAPDEGRP
>Mature_450_residues
MDVSVFGTGYVGLIQAAALADVGHRVLCVDIDPNKIKQLQQAVPPISEPGLSATLEENIKAGRLLFSTQASDAVEHAGLI
FIAVGTPADEDGSADLSHVLNVARQIASCMEDDRTLIIKSTVPVGTADQVLHTAEEELQRRGKNGLAVRVVSNPEFLKEG
SALADCMRPDRIIVGTLDPEAREQMSELYAPFCRNHEKLMFMDNRSAELTKYAANAMLATRISFMNELANLTELLGADIE
AVRKGIGSDPRIGYHFIYPGCGFGGSCFPKDLRALLHTAEHNGMPLKLLRSVTDVNDAQRHILFSKLRAQFPQGLAGKSI
AIWGLAFKPNTDDMREAPSRYLMEALWAEGASVQAYDPEAMSECRRIYGYRNDLHLCATRDDTLEDADALVICTEWKNFR
VVDFELLAEKLRAKVIVDGRNLYNPEQVAAAGLHYSGIGLRHIAPDEGRP

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=460, Percent_Identity=35.2173913043478, Blast_Score=236, Evalue=3e-62,
Organism=Homo sapiens, GI296040438, Length=363, Percent_Identity=35.8126721763085, Blast_Score=191, Evalue=9e-49,
Organism=Homo sapiens, GI296040443, Length=312, Percent_Identity=36.8589743589744, Blast_Score=176, Evalue=4e-44,
Organism=Escherichia coli, GI1788340, Length=360, Percent_Identity=28.6111111111111, Blast_Score=167, Evalue=9e-43,
Organism=Escherichia coli, GI48994968, Length=436, Percent_Identity=27.5229357798165, Blast_Score=154, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17560350, Length=482, Percent_Identity=32.7800829875519, Blast_Score=211, Evalue=7e-55,
Organism=Drosophila melanogaster, GI17136908, Length=472, Percent_Identity=33.6864406779661, Blast_Score=236, Evalue=2e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 49374; Mature: 49374

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVSVFGTGYVGLIQAAALADVGHRVLCVDIDPNKIKQLQQAVPPISEPGLSATLEENIK
CCEEEECCCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHCCCCCCCCCCHHHHHCCC
AGRLLFSTQASDAVEHAGLIFIAVGTPADEDGSADLSHVLNVARQIASCMEDDRTLIIKS
CCEEEEECCHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEE
TVPVGTADQVLHTAEEELQRRGKNGLAVRVVSNPEFLKEGSALADCMRPDRIIVGTLDPE
CCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHCCHHHHHHCCCCEEEEECCCHH
AREQMSELYAPFCRNHEKLMFMDNRSAELTKYAANAMLATRISFMNELANLTELLGADIE
HHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
AVRKGIGSDPRIGYHFIYPGCGFGGSCFPKDLRALLHTAEHNGMPLKLLRSVTDVNDAQR
HHHHCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHH
HILFSKLRAQFPQGLAGKSIAIWGLAFKPNTDDMREAPSRYLMEALWAEGASVQAYDPEA
HHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEECHHH
MSECRRIYGYRNDLHLCATRDDTLEDADALVICTEWKNFRVVDFELLAEKLRAKVIVDGR
HHHHHHHHCCCCCEEEEECCCCCCCCCCEEEEEECCCCCEEEEHHHHHHHHHCEEEECCC
NLYNPEQVAAAGLHYSGIGLRHIAPDEGRP
CCCCHHHHHHHCCEECCCCEEECCCCCCCC
>Mature Secondary Structure
MDVSVFGTGYVGLIQAAALADVGHRVLCVDIDPNKIKQLQQAVPPISEPGLSATLEENIK
CCEEEECCCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHCCCCCCCCCCHHHHHCCC
AGRLLFSTQASDAVEHAGLIFIAVGTPADEDGSADLSHVLNVARQIASCMEDDRTLIIKS
CCEEEEECCHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEE
TVPVGTADQVLHTAEEELQRRGKNGLAVRVVSNPEFLKEGSALADCMRPDRIIVGTLDPE
CCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHCCHHHHHHCCCCEEEEECCCHH
AREQMSELYAPFCRNHEKLMFMDNRSAELTKYAANAMLATRISFMNELANLTELLGADIE
HHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
AVRKGIGSDPRIGYHFIYPGCGFGGSCFPKDLRALLHTAEHNGMPLKLLRSVTDVNDAQR
HHHHCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHH
HILFSKLRAQFPQGLAGKSIAIWGLAFKPNTDDMREAPSRYLMEALWAEGASVQAYDPEA
HHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEECHHH
MSECRRIYGYRNDLHLCATRDDTLEDADALVICTEWKNFRVVDFELLAEKLRAKVIVDGR
HHHHHHHHCCCCCEEEEECCCCCCCCCCEEEEEECCCCCEEEEHHHHHHHHHCEEEECCC
NLYNPEQVAAAGLHYSGIGLRHIAPDEGRP
CCCCHHHHHHHCCEECCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]