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The map label for this gene is infC [H]

Identifier: 77458159

GI number: 77458159

Start: 2202401

End: 2202934

Strand: Direct

Name: infC [H]

Synonym: Pfl01_1932

Alternate gene names: 77458159

Gene position: 2202401-2202934 (Clockwise)

Preceding gene: 77458158

Following gene: 77458160

Centisome position: 34.21

GC content: 52.25

Gene sequence:

>534_bases
ATGAGACAAGATAAACGAGCTGCACCGAAAGCCCCGATCAACGAGAATATCTCGGCACGCGAGGTTCGGTTAATTGGCGC
TGATGGCGAGCAGATTGGCATCGTCTCGATTGATGAAGCGCTTCGTATTGCTGAAGAAGCAAAGCTTGATCTGGTAGAAA
TTTCTGCCGACGCAGTCCCACCGGTTTGCCGTGTGATGGACTACGGCAAATCGATCTTCGAAAAGAAGAAGCAGATTGCT
GCGGCGAAGAAAAACCAGAAGCAGATTCAGGTAAAAGAAATCAAGTTTCGTCCAGGGACGGAGGAAGGGGATTACCAGGT
AAAACTGCGCAACCTGGTACGTTTCCTGAGTGACGGGGACAGGGCCAAGGTATCCTTGCGATTCCGCGGCCGTGAGATGG
CCCACCAGGAGCTGGGGATGGAACTCCTCAAGCGGGTTGAACAAGACCTGCTCGAGTACGGTTCGGTCGAACAGCATCCT
AAGATGGAAGGACGCCAGCTGATCATGGTCATCGCCCCGAAAAAGAAGAAGTAA

Upstream 100 bases:

>100_bases
ACCTGGGCTCGATGCCCGTCGCCCAGTTCGCTGAGTTTCTCGCGCAAGCGGTTTCCCGGCGTGGTCGCCCAGATTCGGAG
TAATTATTATTAAGCGTGAA

Downstream 100 bases:

>100_bases
TCAACAGGGCACGGCAGGCCTTCTGATTATGTTTATCAACTGAATGCGGAGTATCCGAACATGCCAAAGATGAAAACCAA
AAGTGGTGCTGCTAAGCGGT

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MRQDKRAAPKAPINENISAREVRLIGADGEQIGIVSIDEALRIAEEAKLDLVEISADAVPPVCRVMDYGKSIFEKKKQIA
AAKKNQKQIQVKEIKFRPGTEEGDYQVKLRNLVRFLSDGDRAKVSLRFRGREMAHQELGMELLKRVEQDLLEYGSVEQHP
KMEGRQLIMVIAPKKKK

Sequences:

>Translated_177_residues
MRQDKRAAPKAPINENISAREVRLIGADGEQIGIVSIDEALRIAEEAKLDLVEISADAVPPVCRVMDYGKSIFEKKKQIA
AAKKNQKQIQVKEIKFRPGTEEGDYQVKLRNLVRFLSDGDRAKVSLRFRGREMAHQELGMELLKRVEQDLLEYGSVEQHP
KMEGRQLIMVIAPKKKK
>Mature_177_residues
MRQDKRAAPKAPINENISAREVRLIGADGEQIGIVSIDEALRIAEEAKLDLVEISADAVPPVCRVMDYGKSIFEKKKQIA
AAKKNQKQIQVKEIKFRPGTEEGDYQVKLRNLVRFLSDGDRAKVSLRFRGREMAHQELGMELLKRVEQDLLEYGSVEQHP
KMEGRQLIMVIAPKKKK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=180, Percent_Identity=64.4444444444444, Blast_Score=211, Evalue=2e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 20121; Mature: 20121

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQDKRAAPKAPINENISAREVRLIGADGEQIGIVSIDEALRIAEEAKLDLVEISADAVP
CCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEEEHHHHHHHHHHHCCEEEEECCCCCC
PVCRVMDYGKSIFEKKKQIAAAKKNQKQIQVKEIKFRPGTEEGDYQVKLRNLVRFLSDGD
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCC
RAKVSLRFRGREMAHQELGMELLKRVEQDLLEYGSVEQHPKMEGRQLIMVIAPKKKK
CEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure
MRQDKRAAPKAPINENISAREVRLIGADGEQIGIVSIDEALRIAEEAKLDLVEISADAVP
CCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEEEHHHHHHHHHHHCCEEEEECCCCCC
PVCRVMDYGKSIFEKKKQIAAAKKNQKQIQVKEIKFRPGTEEGDYQVKLRNLVRFLSDGD
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCC
RAKVSLRFRGREMAHQELGMELLKRVEQDLLEYGSVEQHPKMEGRQLIMVIAPKKKK
CEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA