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The map label for this gene is usg [H]

Identifier: 77458121

GI number: 77458121

Start: 2163444

End: 2164454

Strand: Direct

Name: usg [H]

Synonym: Pfl01_1894

Alternate gene names: 77458121

Gene position: 2163444-2164454 (Clockwise)

Preceding gene: 77458120

Following gene: 77458122

Centisome position: 33.6

GC content: 62.91

Gene sequence:

>1011_bases
ATGACCCAGACCCTTGATATTGCCGTGATCGGCGCCACCGGTACTGTCGGCGAAACCCTCGTGCAGATTCTCGAGGAGCG
CGACTTCCCGGTCGGCACCTTGCACCTGTTGGCCAGCAGCGAATCCGCCGGCAGCTCGGTGCTGTTTCGCAACAAGAACG
TGCGCGTGCGCGAAGTCGACGAGTTCGATTTCAGCAAGGTCAAACTGGCGTTCTTCGCCGCCGGCCCGGCCATCACCCTG
AGTTACGCCGCCCGCGCTCACGCGGCGGGTTGCTCGCTGGTCGATTTGTCTGGCGCCTTGCCGGCGGATCAGGCGCCGCA
AGTGGTGCCGGAAGCCAATGCCGATGTGCTGGCCGGTTTGAAAGCACCGTTCCAGGTCTGCAGCCCGAGCCCGTCGGCCA
CCACATTGGCCGTGGTGCTGGCGCCGCTGCTCGATCTGATCGAGCTGCACTATGTGCATGTCACCGCCAATCTGGCGGTT
TCCGCCCAAGGCCGCGAAGCCGTGACCGAGCTGGCACGTCAGACCGCCGAGCTGCTGAACATGCGTCCGCTGGAGCCGAC
ATTCTTCGACCGGCAGATGGCTTTCAACCTGCTGGCCCAGGTCGGTACGCCCGACGCGCAAGGTCACACGCTGCTGGAAA
AACGTCTGGTGCGCGAGCTGCGTCAGGTGCTGGCCAAGCCTTTATTAAAGATTTCCGCAACTTGCGTTCAAGCCCCGGTG
TTTTTTGGCGATAGCTTTAGCGTGACCTTGCAGTCAGCGAGCGCGGTCGACCTGGAAAAGGTCAACGCCGCGCTTGAAGA
GGCCGAGGGTATCGAGCTGGTCGAGGCCGGCGATTATCCGACCGCCGTCGGTGACGCGGTCGGGCAGGACGTGGTCTACG
TCGGGCGGGTGCGCGCCGGTGTCGACGAGCCGTCGGAACTTAATCTGTGGCTGACGTCAGATAACGTACGCAAAGGTGCG
GCCCTCAACGCCGTGCAGGTCGCCGAGTTGTTGATAAAAGACCTGCTGTAA

Upstream 100 bases:

>100_bases
TGAAAGAACCCGCGCCTTGCACGAGGCGCGGGTTTTTTTTTGCCTGCGTGGCGGCCACCCGGTAAAGTGCCGCTCCCCCC
GTTTCGCCAGAGGTAGCAAC

Downstream 100 bases:

>100_bases
AAGATACTTGGCAACAATTTGTCGACTGATTCTAGCCGGGCGCTATGCTTGGCCAGATCGCTTGATGACGCGACACCCTC
CGGGACTTTCCGGGGCATCA

Product: aspartate-semialdehyde dehydrogenase

Products: L-4-aspartyl phosphate; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MTQTLDIAVIGATGTVGETLVQILEERDFPVGTLHLLASSESAGSSVLFRNKNVRVREVDEFDFSKVKLAFFAAGPAITL
SYAARAHAAGCSLVDLSGALPADQAPQVVPEANADVLAGLKAPFQVCSPSPSATTLAVVLAPLLDLIELHYVHVTANLAV
SAQGREAVTELARQTAELLNMRPLEPTFFDRQMAFNLLAQVGTPDAQGHTLLEKRLVRELRQVLAKPLLKISATCVQAPV
FFGDSFSVTLQSASAVDLEKVNAALEEAEGIELVEAGDYPTAVGDAVGQDVVYVGRVRAGVDEPSELNLWLTSDNVRKGA
ALNAVQVAELLIKDLL

Sequences:

>Translated_336_residues
MTQTLDIAVIGATGTVGETLVQILEERDFPVGTLHLLASSESAGSSVLFRNKNVRVREVDEFDFSKVKLAFFAAGPAITL
SYAARAHAAGCSLVDLSGALPADQAPQVVPEANADVLAGLKAPFQVCSPSPSATTLAVVLAPLLDLIELHYVHVTANLAV
SAQGREAVTELARQTAELLNMRPLEPTFFDRQMAFNLLAQVGTPDAQGHTLLEKRLVRELRQVLAKPLLKISATCVQAPV
FFGDSFSVTLQSASAVDLEKVNAALEEAEGIELVEAGDYPTAVGDAVGQDVVYVGRVRAGVDEPSELNLWLTSDNVRKGA
ALNAVQVAELLIKDLL
>Mature_335_residues
TQTLDIAVIGATGTVGETLVQILEERDFPVGTLHLLASSESAGSSVLFRNKNVRVREVDEFDFSKVKLAFFAAGPAITLS
YAARAHAAGCSLVDLSGALPADQAPQVVPEANADVLAGLKAPFQVCSPSPSATTLAVVLAPLLDLIELHYVHVTANLAVS
AQGREAVTELARQTAELLNMRPLEPTFFDRQMAFNLLAQVGTPDAQGHTLLEKRLVRELRQVLAKPLLKISATCVQAPVF
FGDSFSVTLQSASAVDLEKVNAALEEAEGIELVEAGDYPTAVGDAVGQDVVYVGRVRAGVDEPSELNLWLTSDNVRKGAA
LNAVQVAELLIKDLL

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=339, Percent_Identity=41.2979351032448, Blast_Score=237, Evalue=6e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012080
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: 1.2.1.11

Molecular weight: Translated: 35634; Mature: 35503

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTLDIAVIGATGTVGETLVQILEERDFPVGTLHLLASSESAGSSVLFRNKNVRVREVD
CCCEEEEEEEECCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEECCCCEEEECC
EFDFSKVKLAFFAAGPAITLSYAARAHAAGCSLVDLSGALPADQAPQVVPEANADVLAGL
CCCCCCEEEEEEECCCCEEEHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCHHHHCC
KAPFQVCSPSPSATTLAVVLAPLLDLIELHYVHVTANLAVSAQGREAVTELARQTAELLN
CCCHHHCCCCCCHHHHHHHHHHHHHHHHHHEEEEEEEEEEECCCHHHHHHHHHHHHHHHC
MRPLEPTFFDRQMAFNLLAQVGTPDAQGHTLLEKRLVRELRQVLAKPLLKISATCVQAPV
CCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
FFGDSFSVTLQSASAVDLEKVNAALEEAEGIELVEAGDYPTAVGDAVGQDVVYVGRVRAG
EECCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHCCCEEEEEHHHCC
VDEPSELNLWLTSDNVRKGAALNAVQVAELLIKDLL
CCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TQTLDIAVIGATGTVGETLVQILEERDFPVGTLHLLASSESAGSSVLFRNKNVRVREVD
CCEEEEEEEECCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEECCCCEEEECC
EFDFSKVKLAFFAAGPAITLSYAARAHAAGCSLVDLSGALPADQAPQVVPEANADVLAGL
CCCCCCEEEEEEECCCCEEEHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCHHHHCC
KAPFQVCSPSPSATTLAVVLAPLLDLIELHYVHVTANLAVSAQGREAVTELARQTAELLN
CCCHHHCCCCCCHHHHHHHHHHHHHHHHHHEEEEEEEEEEECCCHHHHHHHHHHHHHHHC
MRPLEPTFFDRQMAFNLLAQVGTPDAQGHTLLEKRLVRELRQVLAKPLLKISATCVQAPV
CCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
FFGDSFSVTLQSASAVDLEKVNAALEEAEGIELVEAGDYPTAVGDAVGQDVVYVGRVRAG
EECCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHCCCEEEEEHHHCC
VDEPSELNLWLTSDNVRKGAALNAVQVAELLIKDLL
CCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate 4-semialdehyde; phosphate; NADP+

Specific reaction: L-aspartate 4-semialdehyde + phosphate + NADP+ = L-4-aspartyl phosphate + NADPH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9108283 [H]