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The map label for this gene is pucD [H]

Identifier: 77458023

GI number: 77458023

Start: 2001112

End: 2003505

Strand: Reverse

Name: pucD [H]

Synonym: Pfl01_1796

Alternate gene names: 77458023

Gene position: 2003505-2001112 (Counterclockwise)

Preceding gene: 77458024

Following gene: 77458022

Centisome position: 31.12

GC content: 61.99

Gene sequence:

>2394_bases
ATGTCTAATCATCACGGCGTAGAGAAAACGCAAGCTGAACTGGCTGAACTGTTCGCCAAAGACCTGACCACCGGCGTCGG
CCGCAGCGTCAAGCACGACAGCGCCGCCAAGCATGTGTCCGGTGAAGCGCAGTACATCGATGACCGCCTGGAATTCCCCA
ACCAGTTGCACGTTTACGCGCGGCTGTCGGATCGCGCCCACGCGAAAATCATCAGCATCGACACCCAGCCTTGCTACGCC
TTCGAAGGCGTACGCATCGCCATCACCCACGAAGACGTGCCGGGCCTGAAAGACATCGGCCCGTTGCTGCCGGGCGATCC
GCTGCTGGCCATCGATGACGTGCAGTTTGTCGGTCAACCGGTGCTGGCCGTGGCCGCGAAAGACCTGGAAACCGCACGCA
AGGCCGCCATGGCCGCGATCATCGAATACGAAGATCTGGAGCCAGTGCTGGACGTGGTCGAAGCCCTGCGCAAACGCCAC
TTCGTGCTCGACAGCCATACCCATCAACGCGGCGATTCAGCCAATGCGTTGGCCACGGCCGAGCATCGCATTCAAGGCAC
GCTGCACATCGGCGGTCAGGAACACTTCTATCTGGAGACCCAGATCTCCTCGGTGATGCCAACCGAAGACGGCGGCATGA
TCGTCTACTGCTCGACGCAGAACCCCACCGAAGTGCAGAAACTGGTGGCCGAAGTCCTCGACGTTTCGATGAACAAGATC
GTGGTCGACATGCGCCGCATGGGCGGTGGTTTCGGCGGCAAGGAAACCCAGGCCGCGAGCCCGGCGTGCCTGTGCGCAGT
GATCGCGCACCTCACCGGCCAGCCGACCAAGATGCGCCTGCCGCGTGTCGAGGACATGCTGATGACCGGCAAGCGTCACC
CTTTCTACGTCGAGTACGACGTCGGTTTCGACAGCACCGGGCGCCTGCACGGGATCGCGATGGATCTGGCCGGCAACTGC
GGCTGCTCGCCTGACCTGTCGGCCTCGATCGTTGACCGGGCGATGTTCCACTCGGACAACTCGTACTACCTCGGCGATGC
GACCATCAACGGTCACCGCTGCAAGACCAACACCGCGTCGAACACTGCGTACCGTGGTTTCGGCGGCCCGCAAGGGATGG
TCGCGATCGAAGAAGTGATGGACGCCATCGCCCGTCACCTGAACCTCGATCCGCTGGCCGTGCGCAAGGCCAACTACTAC
GGCAAGACCGAGCGCAACGTCACCCATTACTACCAGACCGTCGAGCACAACATGCTCGAGGAAATGACCGCCGAGCTGGA
AGAAAGCAGCCAGTACGCCGAGCGCCGCGAAGCGATCCGTCGCTACAACGCCAACAGTCCGATCCTGAAAAAAGGCCTGG
CGCTGACCCCGGTGAAATTCGGCATTTCCTTCACTGCCAGCTTCCTCAATCAGGCCGGTGCACTGGTGCACGTCTACACC
GACGGCAGCATCCACCTGAACCACGGCGGCACGGAAATGGGCCAGGGCCTGAACACCAAAGTCGCGCAGGTCGTGGCCGA
AGTGTTCCAGGTGGAAATGGATCGCGTGCAGATCACCGCGACCAACACCGACAAGGTGCCGAACACCTCGCCGACCGCGG
CGTCCAGCGGTGCCGACCTCAACGGCAAAGCGGCGCAGAACGCTGCCGAGACAATCAAGCAGCGGCTGGTCGAATTCGCC
GCGCGGCACTACAAGGTCAGCGAAGAAGATGTGGAATTCCACAACGGCCACGTGCGCGTTCGTGACCATATCCTGACCTT
CGAAGCGCTGATTCAGCTGGCGTATTTCAATCAGGTGTCGCTGTCGAGCACCGGGTTCTACAAGACCCCGAAAATCTACT
ACGACCGCAGCCAGGCCCGTGGCCGGCCGTTCTACTACTTCGCCTTCGGCGCGGCGTGCTGCGAAGTGATCGTCGACACC
CTGACCGGCGAGTACAAGATGCTGCGTACCGACATCCTCCACGACGTCGGCGCCTCGCTGAACCCGGCCATCGATATCGG
CCAGGTCGAGGGTGGTTTCGTTCAGGGCATGGGCTGGCTGACCATGGAAGAACTGGTGTGGAACAACAAGGGCAAGCTGA
TGACCAACGGCCCGGCCAGCTACAAGATCCCGGCCGTGGCGGACATGCCGCTGGACCTGCGGGTGAAGCTGGTGGAAAAC
CGCAAGAACCCGGAAGACACGGTGTTCCACTCCAAGGCTGTGGGTGAGCCGCCGTTCATGCTCGGCATCGCCGCGTGGTG
TGCGATCAAGGATGCGGTGGCCAGCCTCGGCGACTACAAGCATCAACCGAAGATCGACGCGCCGGCGACCCCGGAGCGGG
TGTTGTGGGGCTGCGAGCAGATGCGCCAGCTCAAGGCGGTGAAAGCCGTAGAAGCTGAAACCGAGGTTGTTTGA

Upstream 100 bases:

>100_bases
CGCGCCAGCAAGGAATACCGCCTGCTCAGCGCGCAGAACCTGCTGCGCAAATACTTCATCGAACTGCAAACACCGCACAT
CGAGACTCGGGTGACCGCTT

Downstream 100 bases:

>100_bases
TGATCGTTCCCACGCTCTGCGTGGGAATGCAGCCCGCGACGCTCTGCGTCGCATCCTGAACAGCGGACGCGGAGCGTCCA
GTGATGCATTCCCACGCAGA

Product: xanthine dehydrogenase, molybdenum binding subunit apoprotein / xanthine oxidase

Products: NA

Alternate protein names: XDHase subunit D [H]

Number of amino acids: Translated: 797; Mature: 796

Protein sequence:

>797_residues
MSNHHGVEKTQAELAELFAKDLTTGVGRSVKHDSAAKHVSGEAQYIDDRLEFPNQLHVYARLSDRAHAKIISIDTQPCYA
FEGVRIAITHEDVPGLKDIGPLLPGDPLLAIDDVQFVGQPVLAVAAKDLETARKAAMAAIIEYEDLEPVLDVVEALRKRH
FVLDSHTHQRGDSANALATAEHRIQGTLHIGGQEHFYLETQISSVMPTEDGGMIVYCSTQNPTEVQKLVAEVLDVSMNKI
VVDMRRMGGGFGGKETQAASPACLCAVIAHLTGQPTKMRLPRVEDMLMTGKRHPFYVEYDVGFDSTGRLHGIAMDLAGNC
GCSPDLSASIVDRAMFHSDNSYYLGDATINGHRCKTNTASNTAYRGFGGPQGMVAIEEVMDAIARHLNLDPLAVRKANYY
GKTERNVTHYYQTVEHNMLEEMTAELEESSQYAERREAIRRYNANSPILKKGLALTPVKFGISFTASFLNQAGALVHVYT
DGSIHLNHGGTEMGQGLNTKVAQVVAEVFQVEMDRVQITATNTDKVPNTSPTAASSGADLNGKAAQNAAETIKQRLVEFA
ARHYKVSEEDVEFHNGHVRVRDHILTFEALIQLAYFNQVSLSSTGFYKTPKIYYDRSQARGRPFYYFAFGAACCEVIVDT
LTGEYKMLRTDILHDVGASLNPAIDIGQVEGGFVQGMGWLTMEELVWNNKGKLMTNGPASYKIPAVADMPLDLRVKLVEN
RKNPEDTVFHSKAVGEPPFMLGIAAWCAIKDAVASLGDYKHQPKIDAPATPERVLWGCEQMRQLKAVKAVEAETEVV

Sequences:

>Translated_797_residues
MSNHHGVEKTQAELAELFAKDLTTGVGRSVKHDSAAKHVSGEAQYIDDRLEFPNQLHVYARLSDRAHAKIISIDTQPCYA
FEGVRIAITHEDVPGLKDIGPLLPGDPLLAIDDVQFVGQPVLAVAAKDLETARKAAMAAIIEYEDLEPVLDVVEALRKRH
FVLDSHTHQRGDSANALATAEHRIQGTLHIGGQEHFYLETQISSVMPTEDGGMIVYCSTQNPTEVQKLVAEVLDVSMNKI
VVDMRRMGGGFGGKETQAASPACLCAVIAHLTGQPTKMRLPRVEDMLMTGKRHPFYVEYDVGFDSTGRLHGIAMDLAGNC
GCSPDLSASIVDRAMFHSDNSYYLGDATINGHRCKTNTASNTAYRGFGGPQGMVAIEEVMDAIARHLNLDPLAVRKANYY
GKTERNVTHYYQTVEHNMLEEMTAELEESSQYAERREAIRRYNANSPILKKGLALTPVKFGISFTASFLNQAGALVHVYT
DGSIHLNHGGTEMGQGLNTKVAQVVAEVFQVEMDRVQITATNTDKVPNTSPTAASSGADLNGKAAQNAAETIKQRLVEFA
ARHYKVSEEDVEFHNGHVRVRDHILTFEALIQLAYFNQVSLSSTGFYKTPKIYYDRSQARGRPFYYFAFGAACCEVIVDT
LTGEYKMLRTDILHDVGASLNPAIDIGQVEGGFVQGMGWLTMEELVWNNKGKLMTNGPASYKIPAVADMPLDLRVKLVEN
RKNPEDTVFHSKAVGEPPFMLGIAAWCAIKDAVASLGDYKHQPKIDAPATPERVLWGCEQMRQLKAVKAVEAETEVV
>Mature_796_residues
SNHHGVEKTQAELAELFAKDLTTGVGRSVKHDSAAKHVSGEAQYIDDRLEFPNQLHVYARLSDRAHAKIISIDTQPCYAF
EGVRIAITHEDVPGLKDIGPLLPGDPLLAIDDVQFVGQPVLAVAAKDLETARKAAMAAIIEYEDLEPVLDVVEALRKRHF
VLDSHTHQRGDSANALATAEHRIQGTLHIGGQEHFYLETQISSVMPTEDGGMIVYCSTQNPTEVQKLVAEVLDVSMNKIV
VDMRRMGGGFGGKETQAASPACLCAVIAHLTGQPTKMRLPRVEDMLMTGKRHPFYVEYDVGFDSTGRLHGIAMDLAGNCG
CSPDLSASIVDRAMFHSDNSYYLGDATINGHRCKTNTASNTAYRGFGGPQGMVAIEEVMDAIARHLNLDPLAVRKANYYG
KTERNVTHYYQTVEHNMLEEMTAELEESSQYAERREAIRRYNANSPILKKGLALTPVKFGISFTASFLNQAGALVHVYTD
GSIHLNHGGTEMGQGLNTKVAQVVAEVFQVEMDRVQITATNTDKVPNTSPTAASSGADLNGKAAQNAAETIKQRLVEFAA
RHYKVSEEDVEFHNGHVRVRDHILTFEALIQLAYFNQVSLSSTGFYKTPKIYYDRSQARGRPFYYFAFGAACCEVIVDTL
TGEYKMLRTDILHDVGASLNPAIDIGQVEGGFVQGMGWLTMEELVWNNKGKLMTNGPASYKIPAVADMPLDLRVKLVENR
KNPEDTVFHSKAVGEPPFMLGIAAWCAIKDAVASLGDYKHQPKIDAPATPERVLWGCEQMRQLKAVKAVEAETEVV

Specific function: Oxidizes hypoxanthine and xanthine to uric acid [H]

COG id: COG4631

COG function: function code F; Xanthine dehydrogenase, molybdopterin-binding subunit B

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=760, Percent_Identity=43.5526315789474, Blast_Score=613, Evalue=1e-175,
Organism=Homo sapiens, GI71773480, Length=759, Percent_Identity=37.4176548089592, Blast_Score=499, Evalue=1e-141,
Organism=Escherichia coli, GI1789230, Length=751, Percent_Identity=27.2969374167776, Blast_Score=217, Evalue=2e-57,
Organism=Escherichia coli, GI1789246, Length=851, Percent_Identity=25.6169212690952, Blast_Score=204, Evalue=2e-53,
Organism=Escherichia coli, GI1786478, Length=741, Percent_Identity=23.6167341430499, Blast_Score=97, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17540638, Length=771, Percent_Identity=39.1699092088197, Blast_Score=521, Evalue=1e-148,
Organism=Caenorhabditis elegans, GI32566215, Length=731, Percent_Identity=32.96853625171, Blast_Score=363, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI17539860, Length=740, Percent_Identity=34.0540540540541, Blast_Score=355, Evalue=7e-98,
Organism=Drosophila melanogaster, GI17737937, Length=781, Percent_Identity=40.2048655569782, Blast_Score=566, Evalue=1e-161,
Organism=Drosophila melanogaster, GI24647193, Length=761, Percent_Identity=31.4060446780552, Blast_Score=312, Evalue=5e-85,
Organism=Drosophila melanogaster, GI24647197, Length=758, Percent_Identity=29.6833773087071, Blast_Score=289, Evalue=4e-78,
Organism=Drosophila melanogaster, GI24647195, Length=770, Percent_Identity=29.4805194805195, Blast_Score=289, Evalue=6e-78,
Organism=Drosophila melanogaster, GI24647199, Length=770, Percent_Identity=28.8311688311688, Blast_Score=288, Evalue=1e-77,
Organism=Drosophila melanogaster, GI24647201, Length=778, Percent_Identity=27.3778920308483, Blast_Score=267, Evalue=2e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR017609 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.17.1.4 [H]

Molecular weight: Translated: 87566; Mature: 87435

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNHHGVEKTQAELAELFAKDLTTGVGRSVKHDSAAKHVSGEAQYIDDRLEFPNQLHVYA
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHHCCCCEEEEEE
RLSDRAHAKIISIDTQPCYAFEGVRIAITHEDVPGLKDIGPLLPGDPLLAIDDVQFVGQP
EECCCCCEEEEEECCCCCEEECCEEEEEEECCCCCHHHHCCCCCCCCEEEECCHHHHCCC
VLAVAAKDLETARKAAMAAIIEYEDLEPVLDVVEALRKRHFVLDSHTHQRGDSANALATA
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCEEECCCCCCCCCCCCCEEEH
EHRIQGTLHIGGQEHFYLETQISSVMPTEDGGMIVYCSTQNPTEVQKLVAEVLDVSMNKI
HHHEEEEEEECCCCEEEEEEEHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHH
VVDMRRMGGGFGGKETQAASPACLCAVIAHLTGQPTKMRLPRVEDMLMTGKRHPFYVEYD
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEECCCCHHHHHHCCCCCCEEEEEE
VGFDSTGRLHGIAMDLAGNCGCSPDLSASIVDRAMFHSDNSYYLGDATINGHRCKTNTAS
CCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCEEEECEEECCCEECCCCCC
NTAYRGFGGPQGMVAIEEVMDAIARHLNLDPLAVRKANYYGKTERNVTHYYQTVEHNMLE
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHEEECCCCCCCCCCCHHHHHHHHHHHHHH
EMTAELEESSQYAERREAIRRYNANSPILKKGLALTPVKFGISFTASFLNQAGALVHVYT
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCEECCHHHHHHHHHHHHHCCCCEEEEEE
DGSIHLNHGGTEMGQGLNTKVAQVVAEVFQVEMDRVQITATNTDKVPNTSPTAASSGADL
CCEEEECCCCHHHCCCCCHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCCCCCCCC
NGKAAQNAAETIKQRLVEFAARHYKVSEEDVEFHNGHVRVRDHILTFEALIQLAYFNQVS
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEEEHHHHHHHHHHHHHHHCCEE
LSSTGFYKTPKIYYDRSQARGRPFYYFAFGAACCEVIVDTLTGEYKMLRTDILHDVGASL
CCCCCCCCCCCEEEECHHCCCCCEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCC
NPAIDIGQVEGGFVQGMGWLTMEELVWNNKGKLMTNGPASYKIPAVADMPLDLRVKLVEN
CCCEEECCCCCCCCCCCCHHHHHHHHHCCCCCEEECCCCCEECCEEECCCCCEEEEEECC
RKNPEDTVFHSKAVGEPPFMLGIAAWCAIKDAVASLGDYKHQPKIDAPATPERVLWGCEQ
CCCCCHHHEEHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
MRQLKAVKAVEAETEVV
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SNHHGVEKTQAELAELFAKDLTTGVGRSVKHDSAAKHVSGEAQYIDDRLEFPNQLHVYA
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHHCCCCEEEEEE
RLSDRAHAKIISIDTQPCYAFEGVRIAITHEDVPGLKDIGPLLPGDPLLAIDDVQFVGQP
EECCCCCEEEEEECCCCCEEECCEEEEEEECCCCCHHHHCCCCCCCCEEEECCHHHHCCC
VLAVAAKDLETARKAAMAAIIEYEDLEPVLDVVEALRKRHFVLDSHTHQRGDSANALATA
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCEEECCCCCCCCCCCCCEEEH
EHRIQGTLHIGGQEHFYLETQISSVMPTEDGGMIVYCSTQNPTEVQKLVAEVLDVSMNKI
HHHEEEEEEECCCCEEEEEEEHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHH
VVDMRRMGGGFGGKETQAASPACLCAVIAHLTGQPTKMRLPRVEDMLMTGKRHPFYVEYD
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEECCCCHHHHHHCCCCCCEEEEEE
VGFDSTGRLHGIAMDLAGNCGCSPDLSASIVDRAMFHSDNSYYLGDATINGHRCKTNTAS
CCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCEEEECEEECCCEECCCCCC
NTAYRGFGGPQGMVAIEEVMDAIARHLNLDPLAVRKANYYGKTERNVTHYYQTVEHNMLE
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHEEECCCCCCCCCCCHHHHHHHHHHHHHH
EMTAELEESSQYAERREAIRRYNANSPILKKGLALTPVKFGISFTASFLNQAGALVHVYT
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCEECCHHHHHHHHHHHHHCCCCEEEEEE
DGSIHLNHGGTEMGQGLNTKVAQVVAEVFQVEMDRVQITATNTDKVPNTSPTAASSGADL
CCEEEECCCCHHHCCCCCHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCCCCCCCC
NGKAAQNAAETIKQRLVEFAARHYKVSEEDVEFHNGHVRVRDHILTFEALIQLAYFNQVS
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEEEHHHHHHHHHHHHHHHCCEE
LSSTGFYKTPKIYYDRSQARGRPFYYFAFGAACCEVIVDTLTGEYKMLRTDILHDVGASL
CCCCCCCCCCCEEEECHHCCCCCEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCC
NPAIDIGQVEGGFVQGMGWLTMEELVWNNKGKLMTNGPASYKIPAVADMPLDLRVKLVEN
CCCEEECCCCCCCCCCCCHHHHHHHHHCCCCCEEECCCCCEECCEEECCCCCEEEEEECC
RKNPEDTVFHSKAVGEPPFMLGIAAWCAIKDAVASLGDYKHQPKIDAPATPERVLWGCEQ
CCCCCHHHEEHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
MRQLKAVKAVEAETEVV
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 11344136 [H]