Click here to switch to the map view.

The map label for this gene is lysN [H]

Identifier: 77457940

GI number: 77457940

Start: 1908437

End: 1909603

Strand: Direct

Name: lysN [H]

Synonym: Pfl01_1713

Alternate gene names: 77457940

Gene position: 1908437-1909603 (Clockwise)

Preceding gene: 77457935

Following gene: 77457946

Centisome position: 29.64

GC content: 61.87

Gene sequence:

>1167_bases
ATGGCTTTTTCCGAACGTGTCTCGCGCCTCAAAAGTTCTCTGATCCGTGAAATCCTTGCCGCGGCCCAGCGCCCGGAAGT
GATGTCGTTTGCTGGCGGTTTGCCGGCTGAAGCCATGCTGCCGAAGGTTGAATGGGCCGACATGCCACTGTCTCTCGGCC
AGTACGGCATGAGCGAAGGCGAGCCGGCACTGCGCGAAGCGCTGGCAGCAGAGGCGAGAGCGCTGGGTTTGCCGTGTGAG
GCGAGTCAGGTGCTGGTGGTCAGCGGCTCCCAGCAAACTCTGGATCTGGCGGCCAAGCTGTACATCGACAAGGGCACCGA
AATCCTGCTCGAAGCGCCGACCTATCTGGCGGCCCTGCAGATCTTCCAGCTGTTCGGCGCCGATTGCCTGACCGTGCCGC
TGGAGGCTGACGGCCCGAACCTCGCGCAATTGCGTCAGCGTCTGGAACAGCATCGCCCGGCGTTCATCTATCTGATCCCG
ACCTTCCAGAACCCGTCCGCCGTGCGCTACAGCGAAGCCAAGCGCGAAGCCGTTGCGGCATTGCTCGACGAATTCGGCGT
GACCCTGATCGAAGACGAACCCTATCGCGAACTGACCTTCGACGGCGGCAGCGCCCGACCGATTGCCGGACGCCTGAAGA
AATCCAGCTGGATCTACACCGGCACCGTGTCGAAAACCCTGTTGCCGGGCCTGCGAGTCGGCTACCTGATTGCCAGCCCG
GACCTTTTCCCGCATCTGCTCAAACTCAAGCAATCGGCGGATCTGCACACCAACCGCATCGGTCAGTGGCAGGCATTGCA
GTGGATTGGCAGTGAGAAATATCAACAGCACTTGAGTGAATTGCGCGGCTTCTACCGTCAGCGCCGCGACGCCTTTCAAG
CGGCGCTGGAAACCCATTTCGCCGATCTGGCGGACTGGAACACGCCGCAGGGCGGGCTGTTTTTCTGGTTGACCCTGAAG
CAGCCATTGGACACGCGCACGTTGCTGAACACCGCGCTGGCCGACGATGTGGCGTTCATGCCGGGCGAACCATTCTTCCC
CGAGCCGGATCGCAATCCCGGTCATCTGCGCCTGAACTTCAGTCACATCGATCCTTCACGACTCGATGAAGGGCTCAAGC
GTCTGGCGGCGGTGGTGCGCCAGGCACAGGCCGTGCAGGCGGCATAA

Upstream 100 bases:

>100_bases
GTTTTTAAGGTCAAGCATATTGACGTTTCCAGTGAGGCTGTCGTAATTTCAGTCAACAAGTTTGACTCATTTTTACCATG
CCTCGCTAGCGGTGACCTCC

Downstream 100 bases:

>100_bases
AAAAACCGGCCATCAGGCCGGTTTTTTTTGATTCAGACTGCGGCGAACCGCTGGTTCAGATATTCGATGATCGTGTTGGA
CTCATACATCCAGGTGGTCT

Product: class I and II aminotransferase

Products: NA

Alternate protein names: 2-aminoadipate aminotransferase; Alpha-aminoadipate aminotransferase; AAA-AT; AadAT [H]

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MAFSERVSRLKSSLIREILAAAQRPEVMSFAGGLPAEAMLPKVEWADMPLSLGQYGMSEGEPALREALAAEARALGLPCE
ASQVLVVSGSQQTLDLAAKLYIDKGTEILLEAPTYLAALQIFQLFGADCLTVPLEADGPNLAQLRQRLEQHRPAFIYLIP
TFQNPSAVRYSEAKREAVAALLDEFGVTLIEDEPYRELTFDGGSARPIAGRLKKSSWIYTGTVSKTLLPGLRVGYLIASP
DLFPHLLKLKQSADLHTNRIGQWQALQWIGSEKYQQHLSELRGFYRQRRDAFQAALETHFADLADWNTPQGGLFFWLTLK
QPLDTRTLLNTALADDVAFMPGEPFFPEPDRNPGHLRLNFSHIDPSRLDEGLKRLAAVVRQAQAVQAA

Sequences:

>Translated_388_residues
MAFSERVSRLKSSLIREILAAAQRPEVMSFAGGLPAEAMLPKVEWADMPLSLGQYGMSEGEPALREALAAEARALGLPCE
ASQVLVVSGSQQTLDLAAKLYIDKGTEILLEAPTYLAALQIFQLFGADCLTVPLEADGPNLAQLRQRLEQHRPAFIYLIP
TFQNPSAVRYSEAKREAVAALLDEFGVTLIEDEPYRELTFDGGSARPIAGRLKKSSWIYTGTVSKTLLPGLRVGYLIASP
DLFPHLLKLKQSADLHTNRIGQWQALQWIGSEKYQQHLSELRGFYRQRRDAFQAALETHFADLADWNTPQGGLFFWLTLK
QPLDTRTLLNTALADDVAFMPGEPFFPEPDRNPGHLRLNFSHIDPSRLDEGLKRLAAVVRQAQAVQAA
>Mature_387_residues
AFSERVSRLKSSLIREILAAAQRPEVMSFAGGLPAEAMLPKVEWADMPLSLGQYGMSEGEPALREALAAEARALGLPCEA
SQVLVVSGSQQTLDLAAKLYIDKGTEILLEAPTYLAALQIFQLFGADCLTVPLEADGPNLAQLRQRLEQHRPAFIYLIPT
FQNPSAVRYSEAKREAVAALLDEFGVTLIEDEPYRELTFDGGSARPIAGRLKKSSWIYTGTVSKTLLPGLRVGYLIASPD
LFPHLLKLKQSADLHTNRIGQWQALQWIGSEKYQQHLSELRGFYRQRRDAFQAALETHFADLADWNTPQGGLFFWLTLKQ
PLDTRTLLNTALADDVAFMPGEPFFPEPDRNPGHLRLNFSHIDPSRLDEGLKRLAAVVRQAQAVQAA

Specific function: Catalyzes the transfer of an amino group between 2- oxoadipate (2-OA) and glutamate (Glu) to yield alpha-aminodipate (AAA). It can also transaminate glutamate, leucine, and aromatic amino acids. It also conbtributes in the biosynthesis of other amino acid

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=392, Percent_Identity=25.2551020408163, Blast_Score=131, Evalue=8e-31,
Organism=Homo sapiens, GI33469970, Length=392, Percent_Identity=25.2551020408163, Blast_Score=131, Evalue=8e-31,
Organism=Escherichia coli, GI1787710, Length=380, Percent_Identity=23.6842105263158, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1790797, Length=344, Percent_Identity=22.6744186046512, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788722, Length=401, Percent_Identity=23.9401496259352, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI48994949, Length=232, Percent_Identity=26.7241379310345, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321236, Length=484, Percent_Identity=21.900826446281, Blast_Score=90, Evalue=7e-19,
Organism=Drosophila melanogaster, GI21356535, Length=362, Percent_Identity=22.9281767955801, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.39 [H]

Molecular weight: Translated: 43036; Mature: 42905

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFSERVSRLKSSLIREILAAAQRPEVMSFAGGLPAEAMLPKVEWADMPLSLGQYGMSEG
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHCCCCCCCCCCHHHHHCCCCCC
EPALREALAAEARALGLPCEASQVLVVSGSQQTLDLAAKLYIDKGTEILLEAPTYLAALQ
CHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHEECCCCEEEEECHHHHHHHH
IFQLFGADCLTVPLEADGPNLAQLRQRLEQHRPAFIYLIPTFQNPSAVRYSEAKREAVAA
HHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHH
LLDEFGVTLIEDEPYRELTFDGGSARPIAGRLKKSSWIYTGTVSKTLLPGLRVGYLIASP
HHHHHCCEEECCCCCCEEEECCCCCCCHHHHHCCCCEEEECCHHHHHCCCCCEEEEEECC
DLFPHLLKLKQSADLHTNRIGQWQALQWIGSEKYQQHLSELRGFYRQRRDAFQAALETHF
HHHHHHHHHHHCCCCHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADLADWNTPQGGLFFWLTLKQPLDTRTLLNTALADDVAFMPGEPFFPEPDRNPGHLRLNF
HHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCEECCCCCCCCCCCCCCCEEEEEE
SHIDPSRLDEGLKRLAAVVRQAQAVQAA
CCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AFSERVSRLKSSLIREILAAAQRPEVMSFAGGLPAEAMLPKVEWADMPLSLGQYGMSEG
CHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHCCCCCCCCCCHHHHHCCCCCC
EPALREALAAEARALGLPCEASQVLVVSGSQQTLDLAAKLYIDKGTEILLEAPTYLAALQ
CHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHEECCCCEEEEECHHHHHHHH
IFQLFGADCLTVPLEADGPNLAQLRQRLEQHRPAFIYLIPTFQNPSAVRYSEAKREAVAA
HHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHH
LLDEFGVTLIEDEPYRELTFDGGSARPIAGRLKKSSWIYTGTVSKTLLPGLRVGYLIASP
HHHHHCCEEECCCCCCEEEECCCCCCCHHHHHCCCCEEEECCHHHHHCCCCCEEEEEECC
DLFPHLLKLKQSADLHTNRIGQWQALQWIGSEKYQQHLSELRGFYRQRRDAFQAALETHF
HHHHHHHHHHHCCCCHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADLADWNTPQGGLFFWLTLKQPLDTRTLLNTALADDVAFMPGEPFFPEPDRNPGHLRLNF
HHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCEECCCCCCCCCCCCCCCEEEEEE
SHIDPSRLDEGLKRLAAVVRQAQAVQAA
CCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA