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The map label for this gene is minC

Identifier: 77457922

GI number: 77457922

Start: 1891759

End: 1892496

Strand: Reverse

Name: minC

Synonym: Pfl01_1695

Alternate gene names: 77457922

Gene position: 1892496-1891759 (Counterclockwise)

Preceding gene: 77457925

Following gene: 77457921

Centisome position: 29.39

GC content: 63.14

Gene sequence:

>738_bases
ATGAGCCAAACCGAACCGAAAGACCAAGATCCCGTGTTCCAGCTGAAGGGCAGCATGCTCGCCATTACGGTGCTGGAGCT
GTCCCGCAACGACCTGGACAGCCTCGATCGGCAATTGGCCGCCAAAGTCGCCCAGGCACCGAATTTCTTCAGCAACGCGC
CGCTGGTTCTGGCGCTGGACAAACTGCCGCCCAGTGAAGGCGCAGTCGACCTGCCGGGCCTGATGCGTGTGTGCCGCCAG
CACGGCCTGCGCACCCTGGCGATCCGCGCCAGCCGCATCGAAGACATTGCCGCCGCCATCGCCATCGACATCCCGGTACT
GCCGCCGTCCGGCGCCCGCGAGCGACCGCTGGAAAGCGCTGAACCCGTCGCACCGAAGAAGCCGGAAAAACCGCCGGAGC
CAACCGTCAAACCGACCCGCGTCATCACCACGCCAGTACGTGGTGGCCAACAGATATATGCCCAAGGTGGCGATCTGGTG
GTGGTTTCCTCGGTCAGTCCGGGGGCGGAACTTCTCGCCGATGGCAACATCCATGTATACGGCCCGATGCGCGGTCGTGC
GCTGGCCGGGGTCAAGGGCGACACCAAGGCGCGGATTTTCTGTCAGCAACTGAGCGCTGAACTGATCTCCATCGCAGGCC
ATTACAAGGTTTCCGAGGACCTGCGTCGCGATCCGATGTGGGGTTCGGGCGTACAGGTCAGCCTGTCGGGCGACGTGTTG
AACATCATTCGGCTTTAA

Upstream 100 bases:

>100_bases
CAGTGGCCGCGCATTCTACATCGTTCGACCCGGCTTGCGGCCTGCGGGCGTTCTCGTTATAAGTCTCGGCACTTTTAGTG
ACAAGCCGTTGTATGCCGAC

Downstream 100 bases:

>100_bases
CGGATACTGCCGCATTTTCCAAGCATCTCTAAAACGTAGCGAAAACGGCTCAAACGAAGTAGGAAAAAGGCCAAAAGCCG
GATTCCAGCCAAGGCTGTCC

Product: septum formation inhibitor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MSQTEPKDQDPVFQLKGSMLAITVLELSRNDLDSLDRQLAAKVAQAPNFFSNAPLVLALDKLPPSEGAVDLPGLMRVCRQ
HGLRTLAIRASRIEDIAAAIAIDIPVLPPSGARERPLESAEPVAPKKPEKPPEPTVKPTRVITTPVRGGQQIYAQGGDLV
VVSSVSPGAELLADGNIHVYGPMRGRALAGVKGDTKARIFCQQLSAELISIAGHYKVSEDLRRDPMWGSGVQVSLSGDVL
NIIRL

Sequences:

>Translated_245_residues
MSQTEPKDQDPVFQLKGSMLAITVLELSRNDLDSLDRQLAAKVAQAPNFFSNAPLVLALDKLPPSEGAVDLPGLMRVCRQ
HGLRTLAIRASRIEDIAAAIAIDIPVLPPSGARERPLESAEPVAPKKPEKPPEPTVKPTRVITTPVRGGQQIYAQGGDLV
VVSSVSPGAELLADGNIHVYGPMRGRALAGVKGDTKARIFCQQLSAELISIAGHYKVSEDLRRDPMWGSGVQVSLSGDVL
NIIRL
>Mature_244_residues
SQTEPKDQDPVFQLKGSMLAITVLELSRNDLDSLDRQLAAKVAQAPNFFSNAPLVLALDKLPPSEGAVDLPGLMRVCRQH
GLRTLAIRASRIEDIAAAIAIDIPVLPPSGARERPLESAEPVAPKKPEKPPEPTVKPTRVITTPVRGGQQIYAQGGDLVV
VSSVSPGAELLADGNIHVYGPMRGRALAGVKGDTKARIFCQQLSAELISIAGHYKVSEDLRRDPMWGSGVQVSLSGDVLN
IIRL

Specific function: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize ftsZ filaments that have formed before they mature into polar Z rings. Prevents ftsZ polymerization

COG id: COG0850

COG function: function code D; Septum formation inhibitor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the minC family

Homologues:

Organism=Escherichia coli, GI1787424, Length=231, Percent_Identity=39.3939393939394, Blast_Score=153, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MINC_PSEPF (Q3KFL8)

Other databases:

- EMBL:   CP000094
- RefSeq:   YP_347427.1
- ProteinModelPortal:   Q3KFL8
- STRING:   Q3KFL8
- GeneID:   3716666
- GenomeReviews:   CP000094_GR
- KEGG:   pfo:Pfl01_1695
- eggNOG:   COG0850
- HOGENOM:   HBG399077
- OMA:   KGDTKAR
- ProtClustDB:   PRK00339
- BioCyc:   PFLU205922:PFL_1695-MONOMER
- HAMAP:   MF_00267
- InterPro:   IPR016098
- InterPro:   IPR013033
- InterPro:   IPR007874
- InterPro:   IPR005526
- Gene3D:   G3DSA:2.160.20.70
- TIGRFAMs:   TIGR01222

Pfam domain/function: PF03775 MinC_C; PF05209 MinC_N; SSF63848 MinC_C

EC number: NA

Molecular weight: Translated: 26214; Mature: 26082

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQTEPKDQDPVFQLKGSMLAITVLELSRNDLDSLDRQLAAKVAQAPNFFSNAPLVLALD
CCCCCCCCCCCCEEECCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEE
KLPPSEGAVDLPGLMRVCRQHGLRTLAIRASRIEDIAAAIAIDIPVLPPSGARERPLESA
CCCCCCCCCCCHHHHHHHHHCCCEEEEHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCC
EPVAPKKPEKPPEPTVKPTRVITTPVRGGQQIYAQGGDLVVVSSVSPGAELLADGNIHVY
CCCCCCCCCCCCCCCCCCCEEEECCCCCCEEEEECCCCEEEEECCCCCHHHEECCCEEEE
GPMRGRALAGVKGDTKARIFCQQLSAELISIAGHYKVSEDLRRDPMWGSGVQVSLSGDVL
ECCCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEHHHHHCCCCCCCCEEEEECCCEE
NIIRL
EEECC
>Mature Secondary Structure 
SQTEPKDQDPVFQLKGSMLAITVLELSRNDLDSLDRQLAAKVAQAPNFFSNAPLVLALD
CCCCCCCCCCCEEECCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEE
KLPPSEGAVDLPGLMRVCRQHGLRTLAIRASRIEDIAAAIAIDIPVLPPSGARERPLESA
CCCCCCCCCCCHHHHHHHHHCCCEEEEHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCC
EPVAPKKPEKPPEPTVKPTRVITTPVRGGQQIYAQGGDLVVVSSVSPGAELLADGNIHVY
CCCCCCCCCCCCCCCCCCCEEEECCCCCCEEEEECCCCEEEEECCCCCHHHEECCCEEEE
GPMRGRALAGVKGDTKARIFCQQLSAELISIAGHYKVSEDLRRDPMWGSGVQVSLSGDVL
ECCCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEHHHHHCCCCCCCCEEEEECCCEE
NIIRL
EEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA