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The map label for this gene is htpG [H]

Identifier: 77457852

GI number: 77457852

Start: 1815340

End: 1817244

Strand: Direct

Name: htpG [H]

Synonym: Pfl01_1625

Alternate gene names: 77457852

Gene position: 1815340-1817244 (Clockwise)

Preceding gene: 77457851

Following gene: 77457853

Centisome position: 28.2

GC content: 58.06

Gene sequence:

>1905_bases
ATGAGTGTGGAAACTCAAAAGGAAACCCTGGGCTTCCAGACCGAGGTGAAGCAACTGCTGCACCTCATGATCCATTCGCT
GTATTCCAACAAGGAAATCTTCCTTCGCGAATTGATCTCGAACGCCTCTGACGCCGTCGACAAATTGCGCTTCGAAGCCC
TGGCCAAGCCTGAGCTGCTCGAAGATGGCGCTGAACTGAAAATCCGTGTGAGCTTCGACAAGGACGCCAAGACCGTCACC
CTCGAAGACAACGGCATCGGCATGAACCGTGACGATGTGATCACCCACCTGGGTACCATCGCCAAATCCGGCACTGCCGA
TTTCATGAAAAACCTGTCCGGCGATCAGAAGAAGGATTCGCACCTGATCGGTCAGTTCGGTGTGGGTTTCTACTCGGCCT
TCATCGTTGCTGACAAAGTTGACGTGTACAGCCGTCGCGCCGGCACTGCTGCCAGCGAAGGCGTGCACTGGTCGTCGAAA
GGCGAGGGCGAATTCGAAGTCGCCACCATCGACAAGCCGGAGCGCGGCACCCGCATCGTCCTGCACCTGAAATCCGGTGA
AGAGGAGTTTGCCGATGGCTGGCGCCTGCGCAACATCATCAAGAAGTACTCCGACCACATCGCGCTGCCGATCGAGCTGC
CGAAAGAAGTGGCCGCTGCCGAAGGCGAAGAGAAGCCTGAAGTTGAATGGGAAACCGTCAACCGCGCCAGCGCCCTGTGG
ACCCGCCCTCGCACCGAAGTGAAGGACGAGGAATACCAGGAGTTCTACAAACATATCGCTCACGACTTCGAAAACCCGCT
GTCGTGGAGTCACAACAAGGTTGAAGGCAAGCTTGAGTACAGCTCGCTGCTGTATGTGCCGGCCCGCGCACCGTTCGATC
TGTACCAGCGTGAAGCGCCGAAAGGCCTGAAGCTGTACGTGCAGCGCGTGTTCGTGATGGATCAGGCCGAGTCCTTCCTG
CCGCTGTACCTGCGCTTCATCAAGGGCGTGGTCGATTCCAACGACCTGTCGCTGAACGTGTCGCGGGAAATCCTGCAGAA
AGACCCGATCATCGACTCGATGAAGTCGGCGCTGACCAAGCGTGTTCTGGACATGCTGGAAAAACTGGCGAAGAACGAGC
CTGAGCAATACAAGGGCTTCTGGAAAAACTTCGGTCAGGTCATGAAAGAAGGCCCGGCAGAAGATTTCGCCAACAAGGAA
AAAATTGCCGGTCTGTTGCGTTTCGCATCGACCAACGGCACCGATGGCGAGCAGATCGTCGGTCTGGCCGAGTACCTGGC
GCGCGCCAAGGAAGGTCAGGACAAGATCTACTACCTCACCGGCGAAACCTACGCGCAGGTCAAGAACAGCCCGCACCTGG
AAGTCTTCCGCAAGAAAGGCATCGAAGTGCTGCTGCTGACCGACCGTATCGACGAGTGGCTGATGAGCTACCTCAGCGAA
TTCGACGGCAAGACGTTTGTCGACGTCGCGCGCGGTGACCTGGACCTGGGCAACCTGGACTCGGAAGAGGACAAGAAGGC
CGCAGAAGAAGTCGCCAAGTCGAAAGAAGGTCTGGTCGAGCGTCTGAAAACCGCACTGGGCGATTCCGTTGCCGAAGTCC
GGGTTTCCCATCGCCTGACCGATTCGCCGGCCATCCTGGCGATTGGCGAGCAGGACCTGGGTCTGCAAATGCGTCAGATC
CTTGAAGCCAGTGGGCAGAAGGTGCCGGATTCGAAGCCTATCTTCGAATTCAACCCGAGCCACCCGCTGATCGAGAAGCT
CGACAACGAGGCCAGCGAAGATCGCTTCAGCGACCTGTCGCACATCCTCTTCGACCAGGCCGCCCTGGCGGCGGGCGACA
GCTTGAAAGACCCGGCCGCTTACGTGAGCCGTCTGAACAAGCTGCTGGTTGAGCTGTCGGCCTGA

Upstream 100 bases:

>100_bases
TGAGCCCTTGAAATCCTGAAGCACGCCCCCAACTCACAGAACAACCCGCCGCCGACCGGCAAGGTCGCGGCCAATGCCAT
CTGATTGGAGTTTGATGACC

Downstream 100 bases:

>100_bases
TCAAGCTGTAGAAAAACCCGCTTCGGCGGGTTTTTTCATTCTGGAATTCAACCAATCTGGAGTCAGAAATGAGCCAAGTC
ACTGTACGTTCCGTGGTCTA

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 634; Mature: 633

Protein sequence:

>634_residues
MSVETQKETLGFQTEVKQLLHLMIHSLYSNKEIFLRELISNASDAVDKLRFEALAKPELLEDGAELKIRVSFDKDAKTVT
LEDNGIGMNRDDVITHLGTIAKSGTADFMKNLSGDQKKDSHLIGQFGVGFYSAFIVADKVDVYSRRAGTAASEGVHWSSK
GEGEFEVATIDKPERGTRIVLHLKSGEEEFADGWRLRNIIKKYSDHIALPIELPKEVAAAEGEEKPEVEWETVNRASALW
TRPRTEVKDEEYQEFYKHIAHDFENPLSWSHNKVEGKLEYSSLLYVPARAPFDLYQREAPKGLKLYVQRVFVMDQAESFL
PLYLRFIKGVVDSNDLSLNVSREILQKDPIIDSMKSALTKRVLDMLEKLAKNEPEQYKGFWKNFGQVMKEGPAEDFANKE
KIAGLLRFASTNGTDGEQIVGLAEYLARAKEGQDKIYYLTGETYAQVKNSPHLEVFRKKGIEVLLLTDRIDEWLMSYLSE
FDGKTFVDVARGDLDLGNLDSEEDKKAAEEVAKSKEGLVERLKTALGDSVAEVRVSHRLTDSPAILAIGEQDLGLQMRQI
LEASGQKVPDSKPIFEFNPSHPLIEKLDNEASEDRFSDLSHILFDQAALAAGDSLKDPAAYVSRLNKLLVELSA

Sequences:

>Translated_634_residues
MSVETQKETLGFQTEVKQLLHLMIHSLYSNKEIFLRELISNASDAVDKLRFEALAKPELLEDGAELKIRVSFDKDAKTVT
LEDNGIGMNRDDVITHLGTIAKSGTADFMKNLSGDQKKDSHLIGQFGVGFYSAFIVADKVDVYSRRAGTAASEGVHWSSK
GEGEFEVATIDKPERGTRIVLHLKSGEEEFADGWRLRNIIKKYSDHIALPIELPKEVAAAEGEEKPEVEWETVNRASALW
TRPRTEVKDEEYQEFYKHIAHDFENPLSWSHNKVEGKLEYSSLLYVPARAPFDLYQREAPKGLKLYVQRVFVMDQAESFL
PLYLRFIKGVVDSNDLSLNVSREILQKDPIIDSMKSALTKRVLDMLEKLAKNEPEQYKGFWKNFGQVMKEGPAEDFANKE
KIAGLLRFASTNGTDGEQIVGLAEYLARAKEGQDKIYYLTGETYAQVKNSPHLEVFRKKGIEVLLLTDRIDEWLMSYLSE
FDGKTFVDVARGDLDLGNLDSEEDKKAAEEVAKSKEGLVERLKTALGDSVAEVRVSHRLTDSPAILAIGEQDLGLQMRQI
LEASGQKVPDSKPIFEFNPSHPLIEKLDNEASEDRFSDLSHILFDQAALAAGDSLKDPAAYVSRLNKLLVELSA
>Mature_633_residues
SVETQKETLGFQTEVKQLLHLMIHSLYSNKEIFLRELISNASDAVDKLRFEALAKPELLEDGAELKIRVSFDKDAKTVTL
EDNGIGMNRDDVITHLGTIAKSGTADFMKNLSGDQKKDSHLIGQFGVGFYSAFIVADKVDVYSRRAGTAASEGVHWSSKG
EGEFEVATIDKPERGTRIVLHLKSGEEEFADGWRLRNIIKKYSDHIALPIELPKEVAAAEGEEKPEVEWETVNRASALWT
RPRTEVKDEEYQEFYKHIAHDFENPLSWSHNKVEGKLEYSSLLYVPARAPFDLYQREAPKGLKLYVQRVFVMDQAESFLP
LYLRFIKGVVDSNDLSLNVSREILQKDPIIDSMKSALTKRVLDMLEKLAKNEPEQYKGFWKNFGQVMKEGPAEDFANKEK
IAGLLRFASTNGTDGEQIVGLAEYLARAKEGQDKIYYLTGETYAQVKNSPHLEVFRKKGIEVLLLTDRIDEWLMSYLSEF
DGKTFVDVARGDLDLGNLDSEEDKKAAEEVAKSKEGLVERLKTALGDSVAEVRVSHRLTDSPAILAIGEQDLGLQMRQIL
EASGQKVPDSKPIFEFNPSHPLIEKLDNEASEDRFSDLSHILFDQAALAAGDSLKDPAAYVSRLNKLLVELSA

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI20149594, Length=682, Percent_Identity=38.1231671554252, Blast_Score=431, Evalue=1e-121,
Organism=Homo sapiens, GI4507677, Length=685, Percent_Identity=36.9343065693431, Blast_Score=405, Evalue=1e-113,
Organism=Homo sapiens, GI155722983, Length=638, Percent_Identity=36.9905956112853, Blast_Score=390, Evalue=1e-108,
Organism=Homo sapiens, GI154146191, Length=413, Percent_Identity=38.9830508474576, Blast_Score=278, Evalue=1e-74,
Organism=Homo sapiens, GI153792590, Length=413, Percent_Identity=38.9830508474576, Blast_Score=276, Evalue=4e-74,
Organism=Escherichia coli, GI1786679, Length=624, Percent_Identity=59.4551282051282, Blast_Score=781, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=670, Percent_Identity=39.2537313432836, Blast_Score=451, Evalue=1e-127,
Organism=Caenorhabditis elegans, GI17542208, Length=668, Percent_Identity=37.5748502994012, Blast_Score=399, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI115535205, Length=659, Percent_Identity=33.9908952959029, Blast_Score=349, Evalue=3e-96,
Organism=Caenorhabditis elegans, GI115535167, Length=443, Percent_Identity=36.3431151241535, Blast_Score=280, Evalue=2e-75,
Organism=Saccharomyces cerevisiae, GI6323840, Length=680, Percent_Identity=38.8235294117647, Blast_Score=452, Evalue=1e-128,
Organism=Saccharomyces cerevisiae, GI6325016, Length=684, Percent_Identity=38.4502923976608, Blast_Score=448, Evalue=1e-126,
Organism=Drosophila melanogaster, GI17647529, Length=687, Percent_Identity=37.9912663755458, Blast_Score=449, Evalue=1e-126,
Organism=Drosophila melanogaster, GI21357739, Length=677, Percent_Identity=38.109305760709, Blast_Score=412, Evalue=1e-115,
Organism=Drosophila melanogaster, GI24586016, Length=646, Percent_Identity=33.9009287925697, Blast_Score=366, Evalue=1e-101,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 71285; Mature: 71154

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVETQKETLGFQTEVKQLLHLMIHSLYSNKEIFLRELISNASDAVDKLRFEALAKPELL
CCCCCHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
EDGAELKIRVSFDKDAKTVTLEDNGIGMNRDDVITHLGTIAKSGTADFMKNLSGDQKKDS
CCCCCEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHH
HLIGQFGVGFYSAFIVADKVDVYSRRAGTAASEGVHWSSKGEGEFEVATIDKPERGTRIV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEE
LHLKSGEEEFADGWRLRNIIKKYSDHIALPIELPKEVAAAEGEEKPEVEWETVNRASALW
EEECCCCHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHCCCCCCCCCCHHHHHHHHHHH
TRPRTEVKDEEYQEFYKHIAHDFENPLSWSHNKVEGKLEYSSLLYVPARAPFDLYQREAP
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECEEEEECCCCCHHHHHHCCC
KGLKLYVQRVFVMDQAESFLPLYLRFIKGVVDSNDLSLNVSREILQKDPIIDSMKSALTK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHCCCHHHHHHHHHH
RVLDMLEKLAKNEPEQYKGFWKNFGQVMKEGPAEDFANKEKIAGLLRFASTNGTDGEQIV
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHCCCCCCHHHHH
GLAEYLARAKEGQDKIYYLTGETYAQVKNSPHLEVFRKKGIEVLLLTDRIDEWLMSYLSE
HHHHHHHHHHCCCCEEEEECCCHHHHHCCCCCHHHHHHCCCEEEEEHHHHHHHHHHHHHH
FDGKTFVDVARGDLDLGNLDSEEDKKAAEEVAKSKEGLVERLKTALGDSVAEVRVSHRLT
HCCCEEEEHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCC
DSPAILAIGEQDLGLQMRQILEASGQKVPDSKPIFEFNPSHPLIEKLDNEASEDRFSDLS
CCCCEEEECCHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCHHHHHHCCCCHHHHHHHHH
HILFDQAALAAGDSLKDPAAYVSRLNKLLVELSA
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SVETQKETLGFQTEVKQLLHLMIHSLYSNKEIFLRELISNASDAVDKLRFEALAKPELL
CCCCHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
EDGAELKIRVSFDKDAKTVTLEDNGIGMNRDDVITHLGTIAKSGTADFMKNLSGDQKKDS
CCCCCEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHH
HLIGQFGVGFYSAFIVADKVDVYSRRAGTAASEGVHWSSKGEGEFEVATIDKPERGTRIV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEE
LHLKSGEEEFADGWRLRNIIKKYSDHIALPIELPKEVAAAEGEEKPEVEWETVNRASALW
EEECCCCHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHCCCCCCCCCCHHHHHHHHHHH
TRPRTEVKDEEYQEFYKHIAHDFENPLSWSHNKVEGKLEYSSLLYVPARAPFDLYQREAP
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECEEEEECCCCCHHHHHHCCC
KGLKLYVQRVFVMDQAESFLPLYLRFIKGVVDSNDLSLNVSREILQKDPIIDSMKSALTK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHCCCHHHHHHHHHH
RVLDMLEKLAKNEPEQYKGFWKNFGQVMKEGPAEDFANKEKIAGLLRFASTNGTDGEQIV
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHCCCCCCHHHHH
GLAEYLARAKEGQDKIYYLTGETYAQVKNSPHLEVFRKKGIEVLLLTDRIDEWLMSYLSE
HHHHHHHHHHCCCCEEEEECCCHHHHHCCCCCHHHHHHCCCEEEEEHHHHHHHHHHHHHH
FDGKTFVDVARGDLDLGNLDSEEDKKAAEEVAKSKEGLVERLKTALGDSVAEVRVSHRLT
HCCCEEEEHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCC
DSPAILAIGEQDLGLQMRQILEASGQKVPDSKPIFEFNPSHPLIEKLDNEASEDRFSDLS
CCCCEEEECCHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCHHHHHHCCCCHHHHHHHHH
HILFDQAALAAGDSLKDPAAYVSRLNKLLVELSA
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA