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The map label for this gene is sucD [H]

Identifier: 77457845

GI number: 77457845

Start: 1810044

End: 1810928

Strand: Direct

Name: sucD [H]

Synonym: Pfl01_1618

Alternate gene names: 77457845

Gene position: 1810044-1810928 (Clockwise)

Preceding gene: 77457844

Following gene: 77457846

Centisome position: 28.11

GC content: 57.63

Gene sequence:

>885_bases
ATGAGCGTCCTGATCAATAAAGACACCAAAGTAATCTGCCAGGGCTTCACCGGTGCGCAGGGTACTTTCCACTCCGAACA
AGCCATTGCCTACGGCACCAAAATGGTTGGCGGCGTGACGCCAGGCAAAGGTGGCACCACTCACCTGAACCTGCCTGTGT
TCAACACTGTGAAAGAAGCTGTAGAAGCCACTGGCGCCACCGCCAGCGTAATCTACGTTCCGGCTCCTTTCTGCAAGGAC
TCGATCCTGGAAGCAGCTTTCGGCGGCATCAAGCTGATCGTCTGCATCACCGAAGGCATTCCTACCCTGGATATGCTTGA
CGCCAAAGTTAAGTGCGACGAGCTGGGTGTTACCCTGATCGGCCCTAACTGCCCAGGCGTGATCACCCCAGGCGAATGCA
AGATCGGCATCATGCCAGGTCACATTCACTTGCCAGGCAAGGTCGGTATCGTTTCCCGTTCCGGCACCCTGACCTACGAA
GCTGTGAAGCAGACCACTGACGCCGGTTTCGGTCAGTCGACTTGCGTCGGCATCGGTGGTGACCCGATCCCGGGTTCGAA
CTTCATCGACATCCTGAAGCTGTTCCAGGAAGACCCGAAGACCGAAGCGATCGTCATGATCGGCGAGATCGGCGGTTCGG
CTGAAGAAGAAGCGGCTGCCTACATCAAGGCCAACGTGACCAAGCCGGTTGTTTCCTACATCGCTGGTGTGACTGCTCCT
CCGGGCAAGCGCATGGGCCATGCTGGCGCAATCATCTCCGGCGGCAAAGGCACTGCAGACGAGAAATTCGCTGCTCTGCA
AGACGCAGGCGTGAAAACCGTGCGTTCGCTGGCAGACATCGGCAAGGCCCTGGCCGAGCTGACTGGCTGGGAAGTGAAGA
AGTAA

Upstream 100 bases:

>100_bases
TGGGCGCTAAAGTACTGGCAGAAAGCGGTTTGAACATCATCGCTGCTACCAGCCTGACCGACGCTGCTCAACAAGTCGTT
AAAGCTGCGGAGGGCAAGTA

Downstream 100 bases:

>100_bases
GCTTCGGCTGACTTCTCTGCTCCAGCAACAAAGGCCACCTTCGGGTGGCCTTTGTCGTTTCCGGCGTTCGGGTGGACGAT
GGCAATTTATAAGCACTCAC

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MSVLINKDTKVICQGFTGAQGTFHSEQAIAYGTKMVGGVTPGKGGTTHLNLPVFNTVKEAVEATGATASVIYVPAPFCKD
SILEAAFGGIKLIVCITEGIPTLDMLDAKVKCDELGVTLIGPNCPGVITPGECKIGIMPGHIHLPGKVGIVSRSGTLTYE
AVKQTTDAGFGQSTCVGIGGDPIPGSNFIDILKLFQEDPKTEAIVMIGEIGGSAEEEAAAYIKANVTKPVVSYIAGVTAP
PGKRMGHAGAIISGGKGTADEKFAALQDAGVKTVRSLADIGKALAELTGWEVKK

Sequences:

>Translated_294_residues
MSVLINKDTKVICQGFTGAQGTFHSEQAIAYGTKMVGGVTPGKGGTTHLNLPVFNTVKEAVEATGATASVIYVPAPFCKD
SILEAAFGGIKLIVCITEGIPTLDMLDAKVKCDELGVTLIGPNCPGVITPGECKIGIMPGHIHLPGKVGIVSRSGTLTYE
AVKQTTDAGFGQSTCVGIGGDPIPGSNFIDILKLFQEDPKTEAIVMIGEIGGSAEEEAAAYIKANVTKPVVSYIAGVTAP
PGKRMGHAGAIISGGKGTADEKFAALQDAGVKTVRSLADIGKALAELTGWEVKK
>Mature_293_residues
SVLINKDTKVICQGFTGAQGTFHSEQAIAYGTKMVGGVTPGKGGTTHLNLPVFNTVKEAVEATGATASVIYVPAPFCKDS
ILEAAFGGIKLIVCITEGIPTLDMLDAKVKCDELGVTLIGPNCPGVITPGECKIGIMPGHIHLPGKVGIVSRSGTLTYEA
VKQTTDAGFGQSTCVGIGGDPIPGSNFIDILKLFQEDPKTEAIVMIGEIGGSAEEEAAAYIKANVTKPVVSYIAGVTAPP
GKRMGHAGAIISGGKGTADEKFAALQDAGVKTVRSLADIGKALAELTGWEVKK

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=287, Percent_Identity=65.8536585365854, Blast_Score=323, Evalue=1e-88,
Organism=Homo sapiens, GI38569423, Length=255, Percent_Identity=34.9019607843137, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI38569421, Length=255, Percent_Identity=34.9019607843137, Blast_Score=111, Evalue=7e-25,
Organism=Escherichia coli, GI1786949, Length=284, Percent_Identity=88.0281690140845, Blast_Score=499, Evalue=1e-143,
Organism=Caenorhabditis elegans, GI17550194, Length=289, Percent_Identity=63.3217993079585, Blast_Score=335, Evalue=2e-92,
Organism=Caenorhabditis elegans, GI17553126, Length=290, Percent_Identity=59.6551724137931, Blast_Score=319, Evalue=1e-87,
Organism=Caenorhabditis elegans, GI17557344, Length=256, Percent_Identity=31.640625, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17551266, Length=257, Percent_Identity=32.295719844358, Blast_Score=102, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6324716, Length=294, Percent_Identity=52.7210884353742, Blast_Score=278, Evalue=8e-76,
Organism=Drosophila melanogaster, GI21356559, Length=291, Percent_Identity=58.7628865979381, Blast_Score=323, Evalue=1e-88,
Organism=Drosophila melanogaster, GI28574296, Length=288, Percent_Identity=60.7638888888889, Blast_Score=318, Evalue=2e-87,
Organism=Drosophila melanogaster, GI281363477, Length=263, Percent_Identity=31.1787072243346, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI281363475, Length=263, Percent_Identity=31.1787072243346, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI281363473, Length=263, Percent_Identity=31.1787072243346, Blast_Score=112, Evalue=2e-25,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 30169; Mature: 30038

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLINKDTKVICQGFTGAQGTFHSEQAIAYGTKMVGGVTPGKGGTTHLNLPVFNTVKEA
CEEEEECCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEECCHHHHHHHH
VEATGATASVIYVPAPFCKDSILEAAFGGIKLIVCITEGIPTLDMLDAKVKCDELGVTLI
HHHCCCCEEEEEECCCCCHHHHHHHHCCCEEEEEEEECCCCCHHHHCCEEEHHHCCEEEE
GPNCPGVITPGECKIGIMPGHIHLPGKVGIVSRSGTLTYEAVKQTTDAGFGQSTCVGIGG
CCCCCCEECCCCEEEEEECCEEECCCCEEEEECCCCEEHHHHHHHHCCCCCCCEEEECCC
DPIPGSNFIDILKLFQEDPKTEAIVMIGEIGGSAEEEAAAYIKANVTKPVVSYIAGVTAP
CCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHEEEEECCHHHHHHHHHCCCCC
PGKRMGHAGAIISGGKGTADEKFAALQDAGVKTVRSLADIGKALAELTGWEVKK
CCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SVLINKDTKVICQGFTGAQGTFHSEQAIAYGTKMVGGVTPGKGGTTHLNLPVFNTVKEA
EEEEECCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEECCHHHHHHHH
VEATGATASVIYVPAPFCKDSILEAAFGGIKLIVCITEGIPTLDMLDAKVKCDELGVTLI
HHHCCCCEEEEEECCCCCHHHHHHHHCCCEEEEEEEECCCCCHHHHCCEEEHHHCCEEEE
GPNCPGVITPGECKIGIMPGHIHLPGKVGIVSRSGTLTYEAVKQTTDAGFGQSTCVGIGG
CCCCCCEECCCCEEEEEECCEEECCCCEEEEECCCCEEHHHHHHHHCCCCCCCEEEECCC
DPIPGSNFIDILKLFQEDPKTEAIVMIGEIGGSAEEEAAAYIKANVTKPVVSYIAGVTAP
CCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHEEEEECCHHHHHHHHHCCCCC
PGKRMGHAGAIISGGKGTADEKFAALQDAGVKTVRSLADIGKALAELTGWEVKK
CCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043; 8581173 [H]