Click here to switch to the map view.

The map label for this gene is ccmB [H]

Identifier: 77457805

GI number: 77457805

Start: 1767515

End: 1768183

Strand: Direct

Name: ccmB [H]

Synonym: Pfl01_1578

Alternate gene names: 77457805

Gene position: 1767515-1768183 (Clockwise)

Preceding gene: 77457804

Following gene: 77457806

Centisome position: 27.45

GC content: 61.14

Gene sequence:

>669_bases
ATGAGTGTGTTCGGCCTGCTGGTTGCCCGTGAATCCCGACTGCTGTTCCGCCGCCCGGCGGAGCTGGCCAATCCGCTGAT
TTTCTTCGCCATCGTCATCGCGCTGTTCCCGCTGGCCGTCGGACCGGAAACTCAAGTATTGCAAAACTTGTCTCCGGGGT
TAGTCTGGGTGGCGGCACTTTTGTCGGTCCTGCTCTCGCTGGACGGGCTTTTCCGCAGTGATTTCGAAGATGGCTCCCTT
GAACAGTGGGTCCTTTCGCCGCACCCCCTGCCACTTCTGGTATTGGCCAAGGTGCTGGCACACTGGCTTTTTTCCGGGCT
GGCACTGGTTTTGCTCTCGCCGTTACTGGCGTTGATGCTCGGGTTGCCGGCTGCGTGTCTGCCGGTATTGCTGCTTTCGT
TGTTGCTGGGAACACCGGTGCTGAGCTTGCTCGGTGCGGTGGGCGCGGCGCTGACGGTCGGTCTGAAGCGCGGTGGCCTG
TTGCTGGCGCTGCTGATTCTGCCGTTGTACATCCCGGTGTTGATCCTGGGCAGTGGCGCCTTGCAGGCGGCGTTGCAGGG
CATGCCGGCGCTTGGTTATCTGTTGTGGCTTGGCAGCCTGACCGCCCTGGCGATAACCCTGACACCTTTTGCAATAGCGG
CTGGCCTGAAGATCAGCGTCGGCGAATAA

Upstream 100 bases:

>100_bases
GGCACTGCGAACGGGGCGGCCTGGTGGTGCTCACCACACACCACACGCTGAGCCGGATGCCAGCCGGTTATCGCGACATC
GATCTGGGGAATTGGGCGGT

Downstream 100 bases:

>100_bases
TGAGGTCTGGTTAAAATTTAACCAGCAAAGACCCTGAGACTGCTCACACCGATGAGCGGCACCCGTGATGGAAACAGTAT
GAACTGGACCTGGTTTCACA

Product: cytochrome c-type biogenesis protein CcmB

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CcmB [H]

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MSVFGLLVARESRLLFRRPAELANPLIFFAIVIALFPLAVGPETQVLQNLSPGLVWVAALLSVLLSLDGLFRSDFEDGSL
EQWVLSPHPLPLLVLAKVLAHWLFSGLALVLLSPLLALMLGLPAACLPVLLLSLLLGTPVLSLLGAVGAALTVGLKRGGL
LLALLILPLYIPVLILGSGALQAALQGMPALGYLLWLGSLTALAITLTPFAIAAGLKISVGE

Sequences:

>Translated_222_residues
MSVFGLLVARESRLLFRRPAELANPLIFFAIVIALFPLAVGPETQVLQNLSPGLVWVAALLSVLLSLDGLFRSDFEDGSL
EQWVLSPHPLPLLVLAKVLAHWLFSGLALVLLSPLLALMLGLPAACLPVLLLSLLLGTPVLSLLGAVGAALTVGLKRGGL
LLALLILPLYIPVLILGSGALQAALQGMPALGYLLWLGSLTALAITLTPFAIAAGLKISVGE
>Mature_221_residues
SVFGLLVARESRLLFRRPAELANPLIFFAIVIALFPLAVGPETQVLQNLSPGLVWVAALLSVLLSLDGLFRSDFEDGSLE
QWVLSPHPLPLLVLAKVLAHWLFSGLALVLLSPLLALMLGLPAACLPVLLLSLLLGTPVLSLLGAVGAALTVGLKRGGLL
LALLILPLYIPVLILGSGALQAALQGMPALGYLLWLGSLTALAITLTPFAIAAGLKISVGE

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG2386

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmB/CycW/HelB family [H]

Homologues:

Organism=Escherichia coli, GI1788528, Length=210, Percent_Identity=58.5714285714286, Blast_Score=176, Evalue=9e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003544 [H]

Pfam domain/function: PF03379 CcmB [H]

EC number: NA

Molecular weight: Translated: 23181; Mature: 23049

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVFGLLVARESRLLFRRPAELANPLIFFAIVIALFPLAVGPETQVLQNLSPGLVWVAAL
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHH
LSVLLSLDGLFRSDFEDGSLEQWVLSPHPLPLLVLAKVLAHWLFSGLALVLLSPLLALML
HHHHHHHHHHHHCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLPAACLPVLLLSLLLGTPVLSLLGAVGAALTVGLKRGGLLLALLILPLYIPVLILGSGA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHH
LQAALQGMPALGYLLWLGSLTALAITLTPFAIAAGLKISVGE
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCC
>Mature Secondary Structure 
SVFGLLVARESRLLFRRPAELANPLIFFAIVIALFPLAVGPETQVLQNLSPGLVWVAAL
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHH
LSVLLSLDGLFRSDFEDGSLEQWVLSPHPLPLLVLAKVLAHWLFSGLALVLLSPLLALML
HHHHHHHHHHHHCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLPAACLPVLLLSLLLGTPVLSLLGAVGAALTVGLKRGGLLLALLILPLYIPVLILGSGA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHH
LQAALQGMPALGYLLWLGSLTALAITLTPFAIAAGLKISVGE
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]