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The map label for this gene is cheA [H]

Identifier: 77457793

GI number: 77457793

Start: 1755271

End: 1757535

Strand: Direct

Name: cheA [H]

Synonym: Pfl01_1566

Alternate gene names: 77457793

Gene position: 1755271-1757535 (Clockwise)

Preceding gene: 77457792

Following gene: 77457794

Centisome position: 27.26

GC content: 62.52

Gene sequence:

>2265_bases
ATGAGCTTCGGCGCCGATGAAGAGATCCTTCAGGATTTCCTGGTTGAGGCCGGCGAGATTCTTGAGCAACTGTCCGAACA
ACTGGTCGAGCTGGAAAGCCGCCCGGATGACGCAGATCTGCTCAACGCAATTTTTCGCGGTTTCCACACTGTAAAAGGGG
GCGCCGGCTTCCTTCAGCTCAACGAGCTGGTGGAGTGCTGTCACATCGCCGAAAACGTGTTCGACATCCTGCGCAAGGGT
GAACGACGCGTCGATGCAGAACTGATGGACGTGGTGCTTGAAGCGCTGGACGCGGTGAACAGCATGTTCAGCGAAGTCCG
CGATCGCAGCCCGATCACCGCCGCCACCCCGGAACTGCTGGCCGCCCTGGCGCGTCTGGCCGAACCGCAATCGGCGGATG
AAGCCCCGGCTTCGCCGGTTGCCGAGATGATCGAAGAACTGGTCGTCGAAGGCGATTCGGGCGACATCACCGATAACGAA
TTTGAACAGCTGCTGGACTCGCTGAACGCCGTCAAGGCCGAAGCCGAAGCCCCGGCTGCTGCTGCACCTGCTTCCACCGG
AGCGGCCAGCGATGAAATCACCGACGCCGAGTTCGAGTCGCTGCTCGACCAGTTGCATGGCAAGGGCCAGTTCGCGGCCG
ACGCCGTGGCTCCGGCTGCTGCGGCACCTGCTGCTCCGGCGGCGGGCGACAGCTCGGACATCACCGACGACGAATTCGAA
GCCTTGCTCGATCAGTTGCATGGCAAGGGCAACTTTGCTGTTGATGCGCTGGAATCGGCGATTGCTTCGGTGCCTGCGCC
GGCTGCTCCGGCAGCGGCTGCGGCCGGTAGCGATCTGATCACCGACCACGAGTTCGAATCGCTGCTCGACGATCTGCATG
GCAAAGGCAAGTTCACTGACGTCGCCACCGGTGCCGTCGTGACTGCCGGCAATGCTTCGGCAGTTGCAGCGCCTGCTGCG
AAGGCCCCGGCCGCTGCGGCAAAACCTGCTGCAAAAACACCTGAGCCGAAAGCTGAACCGGCCAAGCCAGCCGCTGCGGC
ACCGGCTCCGGCCCGTGCACCGGCGACGCCGCCACCGGAAAAACCGACGACTGAAGCCGAGACCACCGTGCGTGTGGACA
CCGCACGTCTCGACGAAATCATGAACATGGTCGGCGAGCTGGTGCTGGTGCGTAACCGTCTGGTGCGCCTGGGCCTGAAC
AGCGGTGACGAGTCGATGCAGAAGGCCGTGTCGAACCTCGACGTGGTCACCGCCGACTTGCAGACCGCGGTGATGAAGAC
CCGGATGCAGCCGATCAAGAAAGTCTTCGGCCGCTTCCCGCGTCTGGTTCGCGACCTGGCACGCCAGCTCAAGAAAGAGA
TCAACCTGGAACTGGTGGGCGAAGAGACCGACCTCGACAAGAACCTCGTCGAGGCACTGGCCGACCCGCTGGTCCACTTG
GTGCGCAACGCCGTCGACCACGGCATCGAGTCGCCGGAAGAACGCGAAGCCTCGGGCAAGGCCCGTGGCGGCAAGGTGAT
CCTGGCGGCCGAGCAGGAAGGCGACCACATCCTGCTGTCGATCTCCGACGACGGCAAAGGCATGGACCCGAACGTCCTGC
GTGCCATCGCCGTGAAACGCGGTGTGATGGACAAGGATGCCGCCGATCGTCTGAGCGACACCGAGTGCTACAACCTGATT
TTCGCCCCGGGTTTCTCGACCAAGACCGAGATCTCCGACGTGTCCGGCCGCGGTGTCGGCATGGACGTGGTGAAGACCAA
GATTTCCCAGCTCAACGGTTCGATCAACATCTACTCGACCAAGGGCCAGGGCTCGAAGATCGTCATCAAGGTGCCGCTGA
CGCTGGCGATCATGCCGACCCTGATGGTGATGCTCGGCAACCAGGCGTTCGCGTTCCCGCTGGTGAACGTCAACGAAATC
TTCCACCTCGACCTGTCGACCACCAACGTGGTGGACGGCCAGGAAGTGGTGATCGTGCGGGACAAGGCGCTGCCATTGTT
CTACCTCAAGCGCTGGCTGGTCAGCTCCGCCGCTCACGAAGAGCAGCGCGAAGGCCATGTGGTGATTCTTTCGGTGGGCA
CCCAGCGGATCGGCTTCGTCGTCGATCAACTGGTCGGTCAGGAAGAAGTGGTCATCAAGCCATTGGGCAAGATGCTCCAG
GGAACCCCGGGCATGTCCGGCGCCACCATCACCGGTGACGGCCGCATTGCACTGATTCTCGATGTTCCGAGCATGCTCAA
GCGTTACGCCGCACGGCGTATTTGA

Upstream 100 bases:

>100_bases
AGAAGACGTTGTGTCCGGTCAGGACGATGTGGACGATTTGTTATCCAGCCTTGGATTTTGAGTTTTTTTGGGTTTTTAGA
CCTGTAGGAGCACCCCATTA

Downstream 100 bases:

>100_bases
ATCCGGGGTGGCGGGGCGACAACGTCCCGCCGCACCTAATGGAGTGTTTATGGCAGTCAAAGTCCTGGTGGTGGACGATT
CGGGTTTTTTCCGCCGCCGC

Product: CheA Signal transduction histidine kinase (STHK)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 754; Mature: 753

Protein sequence:

>754_residues
MSFGADEEILQDFLVEAGEILEQLSEQLVELESRPDDADLLNAIFRGFHTVKGGAGFLQLNELVECCHIAENVFDILRKG
ERRVDAELMDVVLEALDAVNSMFSEVRDRSPITAATPELLAALARLAEPQSADEAPASPVAEMIEELVVEGDSGDITDNE
FEQLLDSLNAVKAEAEAPAAAAPASTGAASDEITDAEFESLLDQLHGKGQFAADAVAPAAAAPAAPAAGDSSDITDDEFE
ALLDQLHGKGNFAVDALESAIASVPAPAAPAAAAAGSDLITDHEFESLLDDLHGKGKFTDVATGAVVTAGNASAVAAPAA
KAPAAAAKPAAKTPEPKAEPAKPAAAAPAPARAPATPPPEKPTTEAETTVRVDTARLDEIMNMVGELVLVRNRLVRLGLN
SGDESMQKAVSNLDVVTADLQTAVMKTRMQPIKKVFGRFPRLVRDLARQLKKEINLELVGEETDLDKNLVEALADPLVHL
VRNAVDHGIESPEEREASGKARGGKVILAAEQEGDHILLSISDDGKGMDPNVLRAIAVKRGVMDKDAADRLSDTECYNLI
FAPGFSTKTEISDVSGRGVGMDVVKTKISQLNGSINIYSTKGQGSKIVIKVPLTLAIMPTLMVMLGNQAFAFPLVNVNEI
FHLDLSTTNVVDGQEVVIVRDKALPLFYLKRWLVSSAAHEEQREGHVVILSVGTQRIGFVVDQLVGQEEVVIKPLGKMLQ
GTPGMSGATITGDGRIALILDVPSMLKRYAARRI

Sequences:

>Translated_754_residues
MSFGADEEILQDFLVEAGEILEQLSEQLVELESRPDDADLLNAIFRGFHTVKGGAGFLQLNELVECCHIAENVFDILRKG
ERRVDAELMDVVLEALDAVNSMFSEVRDRSPITAATPELLAALARLAEPQSADEAPASPVAEMIEELVVEGDSGDITDNE
FEQLLDSLNAVKAEAEAPAAAAPASTGAASDEITDAEFESLLDQLHGKGQFAADAVAPAAAAPAAPAAGDSSDITDDEFE
ALLDQLHGKGNFAVDALESAIASVPAPAAPAAAAAGSDLITDHEFESLLDDLHGKGKFTDVATGAVVTAGNASAVAAPAA
KAPAAAAKPAAKTPEPKAEPAKPAAAAPAPARAPATPPPEKPTTEAETTVRVDTARLDEIMNMVGELVLVRNRLVRLGLN
SGDESMQKAVSNLDVVTADLQTAVMKTRMQPIKKVFGRFPRLVRDLARQLKKEINLELVGEETDLDKNLVEALADPLVHL
VRNAVDHGIESPEEREASGKARGGKVILAAEQEGDHILLSISDDGKGMDPNVLRAIAVKRGVMDKDAADRLSDTECYNLI
FAPGFSTKTEISDVSGRGVGMDVVKTKISQLNGSINIYSTKGQGSKIVIKVPLTLAIMPTLMVMLGNQAFAFPLVNVNEI
FHLDLSTTNVVDGQEVVIVRDKALPLFYLKRWLVSSAAHEEQREGHVVILSVGTQRIGFVVDQLVGQEEVVIKPLGKMLQ
GTPGMSGATITGDGRIALILDVPSMLKRYAARRI
>Mature_753_residues
SFGADEEILQDFLVEAGEILEQLSEQLVELESRPDDADLLNAIFRGFHTVKGGAGFLQLNELVECCHIAENVFDILRKGE
RRVDAELMDVVLEALDAVNSMFSEVRDRSPITAATPELLAALARLAEPQSADEAPASPVAEMIEELVVEGDSGDITDNEF
EQLLDSLNAVKAEAEAPAAAAPASTGAASDEITDAEFESLLDQLHGKGQFAADAVAPAAAAPAAPAAGDSSDITDDEFEA
LLDQLHGKGNFAVDALESAIASVPAPAAPAAAAAGSDLITDHEFESLLDDLHGKGKFTDVATGAVVTAGNASAVAAPAAK
APAAAAKPAAKTPEPKAEPAKPAAAAPAPARAPATPPPEKPTTEAETTVRVDTARLDEIMNMVGELVLVRNRLVRLGLNS
GDESMQKAVSNLDVVTADLQTAVMKTRMQPIKKVFGRFPRLVRDLARQLKKEINLELVGEETDLDKNLVEALADPLVHLV
RNAVDHGIESPEEREASGKARGGKVILAAEQEGDHILLSISDDGKGMDPNVLRAIAVKRGVMDKDAADRLSDTECYNLIF
APGFSTKTEISDVSGRGVGMDVVKTKISQLNGSINIYSTKGQGSKIVIKVPLTLAIMPTLMVMLGNQAFAFPLVNVNEIF
HLDLSTTNVVDGQEVVIVRDKALPLFYLKRWLVSSAAHEEQREGHVVILSVGTQRIGFVVDQLVGQEEVVIKPLGKMLQG
TPGMSGATITGDGRIALILDVPSMLKRYAARRI

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=422, Percent_Identity=41.7061611374408, Blast_Score=302, Evalue=5e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR010808 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt; PF07194 P2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 79824; Mature: 79693

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: PS50851 CHEW ; PS00018 EF_HAND_1 ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFGADEEILQDFLVEAGEILEQLSEQLVELESRPDDADLLNAIFRGFHTVKGGAGFLQL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHH
NELVECCHIAENVFDILRKGERRVDAELMDVVLEALDAVNSMFSEVRDRSPITAATPELL
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
AALARLAEPQSADEAPASPVAEMIEELVVEGDSGDITDNEFEQLLDSLNAVKAEAEAPAA
HHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
AAPASTGAASDEITDAEFESLLDQLHGKGQFAADAVAPAAAAPAAPAAGDSSDITDDEFE
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCHHCCCCCCCCCCCCCCCHHHHH
ALLDQLHGKGNFAVDALESAIASVPAPAAPAAAAAGSDLITDHEFESLLDDLHGKGKFTD
HHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCHHHHHHHHHHHCCCCCCCE
VATGAVVTAGNASAVAAPAAKAPAAAAKPAAKTPEPKAEPAKPAAAAPAPARAPATPPPE
ECCCCEEECCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
KPTTEAETTVRVDTARLDEIMNMVGELVLVRNRLVRLGLNSGDESMQKAVSNLDVVTADL
CCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCHHHHHHH
QTAVMKTRMQPIKKVFGRFPRLVRDLARQLKKEINLELVGEETDLDKNLVEALADPLVHL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHH
VRNAVDHGIESPEEREASGKARGGKVILAAEQEGDHILLSISDDGKGMDPNVLRAIAVKR
HHHHHHHCCCCCHHHHHCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHH
GVMDKDAADRLSDTECYNLIFAPGFSTKTEISDVSGRGVGMDVVKTKISQLNGSINIYST
CCCCCCHHHHCCCCCHHEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEE
KGQGSKIVIKVPLTLAIMPTLMVMLGNQAFAFPLVNVNEIFHLDLSTTNVVDGQEVVIVR
CCCCCEEEEECCHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEECCCCCCCCCCEEEEEE
DKALPLFYLKRWLVSSAAHEEQREGHVVILSVGTQRIGFVVDQLVGQEEVVIKPLGKMLQ
CCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHC
GTPGMSGATITGDGRIALILDVPSMLKRYAARRI
CCCCCCCCEEECCCCEEEEECCHHHHHHHHHCCC
>Mature Secondary Structure 
SFGADEEILQDFLVEAGEILEQLSEQLVELESRPDDADLLNAIFRGFHTVKGGAGFLQL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHH
NELVECCHIAENVFDILRKGERRVDAELMDVVLEALDAVNSMFSEVRDRSPITAATPELL
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
AALARLAEPQSADEAPASPVAEMIEELVVEGDSGDITDNEFEQLLDSLNAVKAEAEAPAA
HHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
AAPASTGAASDEITDAEFESLLDQLHGKGQFAADAVAPAAAAPAAPAAGDSSDITDDEFE
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCHHCCCCCCCCCCCCCCCHHHHH
ALLDQLHGKGNFAVDALESAIASVPAPAAPAAAAAGSDLITDHEFESLLDDLHGKGKFTD
HHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCHHHHHHHHHHHCCCCCCCE
VATGAVVTAGNASAVAAPAAKAPAAAAKPAAKTPEPKAEPAKPAAAAPAPARAPATPPPE
ECCCCEEECCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
KPTTEAETTVRVDTARLDEIMNMVGELVLVRNRLVRLGLNSGDESMQKAVSNLDVVTADL
CCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCHHHHHHH
QTAVMKTRMQPIKKVFGRFPRLVRDLARQLKKEINLELVGEETDLDKNLVEALADPLVHL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHH
VRNAVDHGIESPEEREASGKARGGKVILAAEQEGDHILLSISDDGKGMDPNVLRAIAVKR
HHHHHHHCCCCCHHHHHCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHH
GVMDKDAADRLSDTECYNLIFAPGFSTKTEISDVSGRGVGMDVVKTKISQLNGSINIYST
CCCCCCHHHHCCCCCHHEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEE
KGQGSKIVIKVPLTLAIMPTLMVMLGNQAFAFPLVNVNEIFHLDLSTTNVVDGQEVVIVR
CCCCCEEEEECCHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEECCCCCCCCCCEEEEEE
DKALPLFYLKRWLVSSAAHEEQREGHVVILSVGTQRIGFVVDQLVGQEEVVIKPLGKMLQ
CCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHC
GTPGMSGATITGDGRIALILDVPSMLKRYAARRI
CCCCCCCCEEECCCCEEEEECCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9255518; 9665876 [H]