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The map label for this gene is flhA [H]

Identifier: 77457787

GI number: 77457787

Start: 1748724

End: 1750853

Strand: Direct

Name: flhA [H]

Synonym: Pfl01_1560

Alternate gene names: 77457787

Gene position: 1748724-1750853 (Clockwise)

Preceding gene: 77457786

Following gene: 77457788

Centisome position: 27.16

GC content: 61.41

Gene sequence:

>2130_bases
GTGGATCGCTCTCAGTTAATCAACAGTGCTCGCTCGAACATTGCCGACCTCAGTCGAGGCAATCTGGGTGTGCCGCTGTT
GCTGCTGGTCATGCTGGCGATGATGATGTTGCCGGTGCCGCCGTTCCTGCTCGACGTGTTCTTCACCTTCAACATTGCCC
TGTCGATCGTCGTGCTGCTGGTCTGCGTGTACGCCTTGCGGCCGCTGGATTTTGCGGTGTTCCCGACGATCCTGCTGGTG
GCGACGCTGTTGCGACTGGCGCTGAACGTGGCGTCGACGCGGGTGGTGATGCTCCACGGTCAGGACGGCCACGCCGCCGC
CGGTAAGGTGATCCAGGCCTTCGGTGAGGTGGTGATCGGCGGTAACTACGTGGTCGGTATCGTGGTCTTCGCGATCCTGA
TGATCATCAACTTCGTCGTGGTGACCAAGGGTGCTGGCCGGATCTCCGAGGTGAGCGCTCGCTTCACCCTCGATGCGATG
CCCGGCAAGCAAATGGCGATCGACGCCGACCTCAACGCCGGTCTGATCGACCAGGCGCAGGCCAAGGCCCGTCGTCAGGA
AGTGGCTCAAGAGGCAGAGTTCTACGGCTCGATGGATGGTGCCAGCAAGTTCGTCCGTGGTGACGCCATCGCCGGCCTGC
TGATTCTGTTCATCAACCTGATCGGCGGCATGGCCGTCGGTATCTTCCAGCACAACATGACTTTCGCCGACGCGGGCAAG
GTTTACGCCTTGCTGACCATCGGTGACGGTTTAGTGGCGCAATTGCCATCACTGTTGTTATCTACAGCTGCAGCGATCAT
GGTGACTCGTGCTTCCGGCTCGGAAGACATGGGCAAGCAGATCAATCGCCAGATGTTCGCCTCGCCCAAAGCGCTGGCGG
TGGCGGCCGGTCTGATGGCGGTCATGGGTCTGGTGCCGGGCATGCCGCACTTCTCGTTCCTGAGCATGGCTGCCCTGGCT
GCCGGTGGTGCTTACCTGTTCTGGAAGAAGCAGAACGTCGCCAAAGTGCAGGCGCTGCAAGAGGTTCAGCGTCAACAGGA
ACTGCTGCCGTCGCCGGCCCGCGCCATGGAAACCAAGGAGCTGGGCTGGGACGACGTGACCCCGATCGACATGATCGGCC
TGGAAGTCGGCTACCGCCTGATTCCGCTGGTGGACCGCAACCAGGGCGGGCAATTGCTGGCGCGGATCAAGGGCGTGCGC
AAGAAGCTCTCGCAGGATCTGGGCTTTCTGATGCCGACCGTGCACATCCGCGACAACCTCGACCTCGCGCCGAGCGCCTA
TCGCCTGACCCTGATGGGCGTGATTCTGGCCGAAGCCGAGATCTACCCGGATCGCGAACTGGCGATCAACCCGGGGCAGG
TCTACGGCTCGCTCAACGGCATTACCGCCAAAGATCCGGCTTTCGGCCTGGAGGCGGTGTGGATCGAAGTCAGCCAGCGC
GCCCAGGCGCAATCGCTCGGTTACACCGTGGTCGATGCCAGCACCGTGGTTGCGACCCACTTGAACCAGATTCTGTACAA
GCACTCCAGCGAGCTGATCGGCCACGAAGAAGTGCAGCAATTGATGCAATTGCTGGCCAAGAGCTCGCCGAAACTGGCTG
AAGAGCTGGTGCCGGGCGTGGTCACGCTGTCGCAACTGCTCAAGGTGTTGCAGGCGTTGCTGGCCGAGCACGTGCCGGTG
CGCGATATCCGCAGCATTGCCGAGGCCATCGCCAACAATGCCGCCAAGAGTCAAGATACCGCCGCTTTGGTGGCTGCTGT
GCGGGTTGGCGTATCGCGCGCCATCGTCCAAAGCATTGTAGGGACTGAGTCGGAGCTGCCAGTTATCACGCTGGAGCCAA
GGTTGGAACAAATATTGCTCAATAGTCTGCAGAAGGCAGGACAAGGCTCGGAAGAGGGCGTTCTGCTGGAGCCGAGCATG
GCCGAGAAGCTGCAGCGTTCGCTGATCGAAGCGGCGCAGCGCCAGGAAATGCAAGGTCAGCCGGTGATTCTGTTGGTAGC
AGGCCCGGTTCGCGCGATGCTCTCGCGCTTTGGTCGCCTGGCAGTTCCCGGACTGCATGTGCTGGCCTACCAGGAAATTC
CGGACAACAAGCAAGTGACCATCGTTGCGACAGTAGGGCCCAACGGCTGA

Upstream 100 bases:

>100_bases
CTATTTCAATCCCCCGCAAAAGTTGGAAGGCTTCTTGCAGTAGCCGCCGTGCGCCTGCTTCGGGCGTCAAAAGTTTGCTT
TAAAGGAACGGGGAAAACCG

Downstream 100 bases:

>100_bases
GGTAGTGGTTTATGCAAGTTAAGCGTTTTTTCGCCGCCGATATGCGTCAGGCCATGAAGCTGGTTCGTGATGAGCTGGGC
GCTGATGCCGCCATCATTGG

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 709; Mature: 709

Protein sequence:

>709_residues
MDRSQLINSARSNIADLSRGNLGVPLLLLVMLAMMMLPVPPFLLDVFFTFNIALSIVVLLVCVYALRPLDFAVFPTILLV
ATLLRLALNVASTRVVMLHGQDGHAAAGKVIQAFGEVVIGGNYVVGIVVFAILMIINFVVVTKGAGRISEVSARFTLDAM
PGKQMAIDADLNAGLIDQAQAKARRQEVAQEAEFYGSMDGASKFVRGDAIAGLLILFINLIGGMAVGIFQHNMTFADAGK
VYALLTIGDGLVAQLPSLLLSTAAAIMVTRASGSEDMGKQINRQMFASPKALAVAAGLMAVMGLVPGMPHFSFLSMAALA
AGGAYLFWKKQNVAKVQALQEVQRQQELLPSPARAMETKELGWDDVTPIDMIGLEVGYRLIPLVDRNQGGQLLARIKGVR
KKLSQDLGFLMPTVHIRDNLDLAPSAYRLTLMGVILAEAEIYPDRELAINPGQVYGSLNGITAKDPAFGLEAVWIEVSQR
AQAQSLGYTVVDASTVVATHLNQILYKHSSELIGHEEVQQLMQLLAKSSPKLAEELVPGVVTLSQLLKVLQALLAEHVPV
RDIRSIAEAIANNAAKSQDTAALVAAVRVGVSRAIVQSIVGTESELPVITLEPRLEQILLNSLQKAGQGSEEGVLLEPSM
AEKLQRSLIEAAQRQEMQGQPVILLVAGPVRAMLSRFGRLAVPGLHVLAYQEIPDNKQVTIVATVGPNG

Sequences:

>Translated_709_residues
MDRSQLINSARSNIADLSRGNLGVPLLLLVMLAMMMLPVPPFLLDVFFTFNIALSIVVLLVCVYALRPLDFAVFPTILLV
ATLLRLALNVASTRVVMLHGQDGHAAAGKVIQAFGEVVIGGNYVVGIVVFAILMIINFVVVTKGAGRISEVSARFTLDAM
PGKQMAIDADLNAGLIDQAQAKARRQEVAQEAEFYGSMDGASKFVRGDAIAGLLILFINLIGGMAVGIFQHNMTFADAGK
VYALLTIGDGLVAQLPSLLLSTAAAIMVTRASGSEDMGKQINRQMFASPKALAVAAGLMAVMGLVPGMPHFSFLSMAALA
AGGAYLFWKKQNVAKVQALQEVQRQQELLPSPARAMETKELGWDDVTPIDMIGLEVGYRLIPLVDRNQGGQLLARIKGVR
KKLSQDLGFLMPTVHIRDNLDLAPSAYRLTLMGVILAEAEIYPDRELAINPGQVYGSLNGITAKDPAFGLEAVWIEVSQR
AQAQSLGYTVVDASTVVATHLNQILYKHSSELIGHEEVQQLMQLLAKSSPKLAEELVPGVVTLSQLLKVLQALLAEHVPV
RDIRSIAEAIANNAAKSQDTAALVAAVRVGVSRAIVQSIVGTESELPVITLEPRLEQILLNSLQKAGQGSEEGVLLEPSM
AEKLQRSLIEAAQRQEMQGQPVILLVAGPVRAMLSRFGRLAVPGLHVLAYQEIPDNKQVTIVATVGPNG
>Mature_709_residues
MDRSQLINSARSNIADLSRGNLGVPLLLLVMLAMMMLPVPPFLLDVFFTFNIALSIVVLLVCVYALRPLDFAVFPTILLV
ATLLRLALNVASTRVVMLHGQDGHAAAGKVIQAFGEVVIGGNYVVGIVVFAILMIINFVVVTKGAGRISEVSARFTLDAM
PGKQMAIDADLNAGLIDQAQAKARRQEVAQEAEFYGSMDGASKFVRGDAIAGLLILFINLIGGMAVGIFQHNMTFADAGK
VYALLTIGDGLVAQLPSLLLSTAAAIMVTRASGSEDMGKQINRQMFASPKALAVAAGLMAVMGLVPGMPHFSFLSMAALA
AGGAYLFWKKQNVAKVQALQEVQRQQELLPSPARAMETKELGWDDVTPIDMIGLEVGYRLIPLVDRNQGGQLLARIKGVR
KKLSQDLGFLMPTVHIRDNLDLAPSAYRLTLMGVILAEAEIYPDRELAINPGQVYGSLNGITAKDPAFGLEAVWIEVSQR
AQAQSLGYTVVDASTVVATHLNQILYKHSSELIGHEEVQQLMQLLAKSSPKLAEELVPGVVTLSQLLKVLQALLAEHVPV
RDIRSIAEAIANNAAKSQDTAALVAAVRVGVSRAIVQSIVGTESELPVITLEPRLEQILLNSLQKAGQGSEEGVLLEPSM
AEKLQRSLIEAAQRQEMQGQPVILLVAGPVRAMLSRFGRLAVPGLHVLAYQEIPDNKQVTIVATVGPNG

Specific function: Required for formation of the rod structure of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=685, Percent_Identity=53.1386861313869, Blast_Score=694, Evalue=0.0,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 75914; Mature: 75914

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS00994 FHIPEP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRSQLINSARSNIADLSRGNLGVPLLLLVMLAMMMLPVPPFLLDVFFTFNIALSIVVLL
CCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
VCVYALRPLDFAVFPTILLVATLLRLALNVASTRVVMLHGQDGHAAAGKVIQAFGEVVIG
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHCCEEEC
GNYVVGIVVFAILMIINFVVVTKGAGRISEVSARFTLDAMPGKQMAIDADLNAGLIDQAQ
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHEEEECCCCCCEEEECCCCCCCHHHHH
AKARRQEVAQEAEFYGSMDGASKFVRGDAIAGLLILFINLIGGMAVGIFQHNMTFADAGK
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCC
VYALLTIGDGLVAQLPSLLLSTAAAIMVTRASGSEDMGKQINRQMFASPKALAVAAGLMA
EEEEEEECCCHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
VMGLVPGMPHFSFLSMAALAAGGAYLFWKKQNVAKVQALQEVQRQQELLPSPARAMETKE
HHHHCCCCCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHH
LGWDDVTPIDMIGLEVGYRLIPLVDRNQGGQLLARIKGVRKKLSQDLGFLMPTVHIRDNL
CCCCCCCCHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCC
DLAPSAYRLTLMGVILAEAEIYPDRELAINPGQVYGSLNGITAKDPAFGLEAVWIEVSQR
CCCCCHHHHHHHHHHHHHHHCCCCCCEEECCHHHHCCCCCCCCCCCCCCHHHHHHHHHHH
AQAQSLGYTVVDASTVVATHLNQILYKHSSELIGHEEVQQLMQLLAKSSPKLAEELVPGV
HHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHCCHH
VTLSQLLKVLQALLAEHVPVRDIRSIAEAIANNAAKSQDTAALVAAVRVGVSRAIVQSIV
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GTESELPVITLEPRLEQILLNSLQKAGQGSEEGVLLEPSMAEKLQRSLIEAAQRQEMQGQ
CCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHCCCC
PVILLVAGPVRAMLSRFGRLAVPGLHVLAYQEIPDNKQVTIVATVGPNG
CEEEEECCHHHHHHHHCCCCCCCCEEEEEEECCCCCCCEEEEEEECCCC
>Mature Secondary Structure
MDRSQLINSARSNIADLSRGNLGVPLLLLVMLAMMMLPVPPFLLDVFFTFNIALSIVVLL
CCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
VCVYALRPLDFAVFPTILLVATLLRLALNVASTRVVMLHGQDGHAAAGKVIQAFGEVVIG
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHCCEEEC
GNYVVGIVVFAILMIINFVVVTKGAGRISEVSARFTLDAMPGKQMAIDADLNAGLIDQAQ
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHEEEECCCCCCEEEECCCCCCCHHHHH
AKARRQEVAQEAEFYGSMDGASKFVRGDAIAGLLILFINLIGGMAVGIFQHNMTFADAGK
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCC
VYALLTIGDGLVAQLPSLLLSTAAAIMVTRASGSEDMGKQINRQMFASPKALAVAAGLMA
EEEEEEECCCHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
VMGLVPGMPHFSFLSMAALAAGGAYLFWKKQNVAKVQALQEVQRQQELLPSPARAMETKE
HHHHCCCCCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHH
LGWDDVTPIDMIGLEVGYRLIPLVDRNQGGQLLARIKGVRKKLSQDLGFLMPTVHIRDNL
CCCCCCCCHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCC
DLAPSAYRLTLMGVILAEAEIYPDRELAINPGQVYGSLNGITAKDPAFGLEAVWIEVSQR
CCCCCHHHHHHHHHHHHHHHCCCCCCEEECCHHHHCCCCCCCCCCCCCCHHHHHHHHHHH
AQAQSLGYTVVDASTVVATHLNQILYKHSSELIGHEEVQQLMQLLAKSSPKLAEELVPGV
HHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHCCHH
VTLSQLLKVLQALLAEHVPVRDIRSIAEAIANNAAKSQDTAALVAAVRVGVSRAIVQSIV
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GTESELPVITLEPRLEQILLNSLQKAGQGSEEGVLLEPSMAEKLQRSLIEAAQRQEMQGQ
CCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHCCCC
PVILLVAGPVRAMLSRFGRLAVPGLHVLAYQEIPDNKQVTIVATVGPNG
CEEEEECCHHHHHHHHCCCCCCCCEEEEEEECCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]