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The map label for this gene is phhC [H]

Identifier: 77457724

GI number: 77457724

Start: 1675667

End: 1676860

Strand: Reverse

Name: phhC [H]

Synonym: Pfl01_1497

Alternate gene names: 77457724

Gene position: 1676860-1675667 (Counterclockwise)

Preceding gene: 77457725

Following gene: 77457723

Centisome position: 26.04

GC content: 64.49

Gene sequence:

>1194_bases
ATGCACTTCGACGCCATCGGCCGAGTGCCCGGCGACCCGATCCTCGGTCTGATGGAGGCCTACGCGCAGGATTCCAACCC
GCGCAAGTTCGACCTTGGCGTGGGCGTCTACAAGGATGCCCAGGGCCTGACGCCGATCCCCGAGGCGGTGAAAATCGCCG
AGGCGCGTCTGGTCGAGAGCCAGGACACCAAGACCTACATCGGTGGCCACGGCAATCCGCTGTTCGGCAAGGTCATCAAT
GAGCTGGTGCTTGGCGTCGATTCGAAGCTGATCGCCGAGCAACGCGCCGGCGCCACCCAAACGCCGGGCGGTACTGGCGC
CCTGCGTCTGGCGGCGGACTTCATCGCCCAATGCCTGCCGGGCAAGGGTGTATGGCTGAGCAACCCGACCTGGCCGATCC
ACGAAACGATTTTCGCGGCCGCCGGGGTCAAGATCAGCCATTACCCGTACGTCGGCAGCGACAACCGCCTCGACGTCGAT
GCGATGCTCGCCGTGCTCAACGAAGTGCCGAAAGGTGATGTGGTGCTGCTGCACGCGTGCTGCCACAACCCGACCGGTTT
CGACCTGAGCCACGACGACTGGCAGCGAGTGCTGGAGGTAGTACGCCGCCGTGACCTGCTGCCGCTGATCGACTTTGCCT
ACCAGGGCTTTGGCGACGGTCTGGAGCAGGATGCATGGTCGACCCGGCTGTTCGCCGCCGAGTTGCCCGAGCTGCTGATC
ACCAGCTCCTGCTCGAAGAACTTCGGTTTATATCGCGACCGCACCGGTGCGTTGATCGTCAGCGCGAAAACCGCTGACAA
GCTGATCGACATCCGCAGCCAGTTGGCGCACATCGCCCGCAACCTGTGGTCAACGCCACCGGATCACGGCGCGGCTGTGG
TCGCCACGATCCTCGCCGACCCGGAGCTGAAACGCCGCTGGGCCGACGAAGTGGAAGCCATGCGTCTGCGCATCGCCCAG
TTGCGCAGCGGACTGGTGGAAGCGCTGGAACCGCACGGCCTGCGCGAGCGTTTTGCGCACATCGGCGTGCAACGCGGGAT
GTTCTCCTACACCGGACTGTCGCCGGAACAGGTGAAGAACCTGCGTGAGCATCACAGCGTGTACATGGTCAGCTCGGGCC
GGGCCAACGTTGCCGGGATTGATGCGACGCGTCTCGACCTGCTGGCCGAAGCGATCGCCAACGTCTGCAAATAG

Upstream 100 bases:

>100_bases
TGACCTGGTGGAGCCACTCCATCAAAGGCCTGCATCGCAACGACTTCATCATGGCCGCGCGCACTGACGAAGTGGCCAAG
ACCGCAGAAGGACGCAAGTA

Downstream 100 bases:

>100_bases
TCCCAACTGTGGGAGCGAGCAGGCTCGCTCCCACATCTGCCCTGCGTCACCCTGTCGCACTTGTCTAGACAATCCCGCCC
GTCGAACCAAATGGATTTAA

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MHFDAIGRVPGDPILGLMEAYAQDSNPRKFDLGVGVYKDAQGLTPIPEAVKIAEARLVESQDTKTYIGGHGNPLFGKVIN
ELVLGVDSKLIAEQRAGATQTPGGTGALRLAADFIAQCLPGKGVWLSNPTWPIHETIFAAAGVKISHYPYVGSDNRLDVD
AMLAVLNEVPKGDVVLLHACCHNPTGFDLSHDDWQRVLEVVRRRDLLPLIDFAYQGFGDGLEQDAWSTRLFAAELPELLI
TSSCSKNFGLYRDRTGALIVSAKTADKLIDIRSQLAHIARNLWSTPPDHGAAVVATILADPELKRRWADEVEAMRLRIAQ
LRSGLVEALEPHGLRERFAHIGVQRGMFSYTGLSPEQVKNLREHHSVYMVSSGRANVAGIDATRLDLLAEAIANVCK

Sequences:

>Translated_397_residues
MHFDAIGRVPGDPILGLMEAYAQDSNPRKFDLGVGVYKDAQGLTPIPEAVKIAEARLVESQDTKTYIGGHGNPLFGKVIN
ELVLGVDSKLIAEQRAGATQTPGGTGALRLAADFIAQCLPGKGVWLSNPTWPIHETIFAAAGVKISHYPYVGSDNRLDVD
AMLAVLNEVPKGDVVLLHACCHNPTGFDLSHDDWQRVLEVVRRRDLLPLIDFAYQGFGDGLEQDAWSTRLFAAELPELLI
TSSCSKNFGLYRDRTGALIVSAKTADKLIDIRSQLAHIARNLWSTPPDHGAAVVATILADPELKRRWADEVEAMRLRIAQ
LRSGLVEALEPHGLRERFAHIGVQRGMFSYTGLSPEQVKNLREHHSVYMVSSGRANVAGIDATRLDLLAEAIANVCK
>Mature_397_residues
MHFDAIGRVPGDPILGLMEAYAQDSNPRKFDLGVGVYKDAQGLTPIPEAVKIAEARLVESQDTKTYIGGHGNPLFGKVIN
ELVLGVDSKLIAEQRAGATQTPGGTGALRLAADFIAQCLPGKGVWLSNPTWPIHETIFAAAGVKISHYPYVGSDNRLDVD
AMLAVLNEVPKGDVVLLHACCHNPTGFDLSHDDWQRVLEVVRRRDLLPLIDFAYQGFGDGLEQDAWSTRLFAAELPELLI
TSSCSKNFGLYRDRTGALIVSAKTADKLIDIRSQLAHIARNLWSTPPDHGAAVVATILADPELKRRWADEVEAMRLRIAQ
LRSGLVEALEPHGLRERFAHIGVQRGMFSYTGLSPEQVKNLREHHSVYMVSSGRANVAGIDATRLDLLAEAIANVCK

Specific function: Unknown

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI73486658, Length=392, Percent_Identity=39.030612244898, Blast_Score=280, Evalue=1e-75,
Organism=Homo sapiens, GI4504067, Length=388, Percent_Identity=39.4329896907216, Blast_Score=276, Evalue=2e-74,
Organism=Homo sapiens, GI117414139, Length=384, Percent_Identity=27.6041666666667, Blast_Score=157, Evalue=2e-38,
Organism=Escherichia coli, GI1787159, Length=394, Percent_Identity=47.4619289340102, Blast_Score=368, Evalue=1e-103,
Organism=Escherichia coli, GI1790488, Length=395, Percent_Identity=41.7721518987342, Blast_Score=315, Evalue=3e-87,
Organism=Caenorhabditis elegans, GI25147133, Length=390, Percent_Identity=40, Blast_Score=302, Evalue=2e-82,
Organism=Caenorhabditis elegans, GI71981858, Length=397, Percent_Identity=37.5314861460957, Blast_Score=300, Evalue=6e-82,
Organism=Caenorhabditis elegans, GI17569539, Length=394, Percent_Identity=35.5329949238579, Blast_Score=265, Evalue=4e-71,
Organism=Caenorhabditis elegans, GI17569537, Length=392, Percent_Identity=29.5918367346939, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI25147136, Length=204, Percent_Identity=40.1960784313725, Blast_Score=162, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17550384, Length=262, Percent_Identity=32.0610687022901, Blast_Score=155, Evalue=4e-38,
Organism=Saccharomyces cerevisiae, GI6323055, Length=406, Percent_Identity=36.2068965517241, Blast_Score=271, Evalue=2e-73,
Organism=Saccharomyces cerevisiae, GI6322743, Length=431, Percent_Identity=31.322505800464, Blast_Score=214, Evalue=2e-56,
Organism=Drosophila melanogaster, GI24654046, Length=387, Percent_Identity=39.2764857881137, Blast_Score=279, Evalue=2e-75,
Organism=Drosophila melanogaster, GI19922362, Length=387, Percent_Identity=39.2764857881137, Blast_Score=278, Evalue=4e-75,
Organism=Drosophila melanogaster, GI24580970, Length=398, Percent_Identity=37.6884422110553, Blast_Score=277, Evalue=8e-75,
Organism=Drosophila melanogaster, GI24580972, Length=398, Percent_Identity=37.6884422110553, Blast_Score=277, Evalue=8e-75,
Organism=Drosophila melanogaster, GI19920542, Length=391, Percent_Identity=38.1074168797954, Blast_Score=276, Evalue=2e-74,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.57 [H]

Molecular weight: Translated: 43319; Mature: 43319

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHFDAIGRVPGDPILGLMEAYAQDSNPRKFDLGVGVYKDAQGLTPIPEAVKIAEARLVES
CCCCCCCCCCCCHHHHHHHHHHCCCCCCEEECCCCEECCCCCCCCCHHHHHHHHHHHHCC
QDTKTYIGGHGNPLFGKVINELVLGVDSKLIAEQRAGATQTPGGTGALRLAADFIAQCLP
CCCCEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCC
GKGVWLSNPTWPIHETIFAAAGVKISHYPYVGSDNRLDVDAMLAVLNEVPKGDVVLLHAC
CCCEECCCCCCCHHHHHHHHCCCEEECCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEC
CHNPTGFDLSHDDWQRVLEVVRRRDLLPLIDFAYQGFGDGLEQDAWSTRLFAAELPELLI
CCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
TSSCSKNFGLYRDRTGALIVSAKTADKLIDIRSQLAHIARNLWSTPPDHGAAVVATILAD
HHCCCCCCCCEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCC
PELKRRWADEVEAMRLRIAQLRSGLVEALEPHGLRERFAHIGVQRGMFSYTGLSPEQVKN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHCCCCCHHHHHH
LREHHSVYMVSSGRANVAGIDATRLDLLAEAIANVCK
HHHHCCEEEEECCCCCEECCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHFDAIGRVPGDPILGLMEAYAQDSNPRKFDLGVGVYKDAQGLTPIPEAVKIAEARLVES
CCCCCCCCCCCCHHHHHHHHHHCCCCCCEEECCCCEECCCCCCCCCHHHHHHHHHHHHCC
QDTKTYIGGHGNPLFGKVINELVLGVDSKLIAEQRAGATQTPGGTGALRLAADFIAQCLP
CCCCEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCC
GKGVWLSNPTWPIHETIFAAAGVKISHYPYVGSDNRLDVDAMLAVLNEVPKGDVVLLHAC
CCCEECCCCCCCHHHHHHHHCCCEEECCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEC
CHNPTGFDLSHDDWQRVLEVVRRRDLLPLIDFAYQGFGDGLEQDAWSTRLFAAELPELLI
CCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
TSSCSKNFGLYRDRTGALIVSAKTADKLIDIRSQLAHIARNLWSTPPDHGAAVVATILAD
HHCCCCCCCCEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCC
PELKRRWADEVEAMRLRIAQLRSGLVEALEPHGLRERFAHIGVQRGMFSYTGLSPEQVKN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHCCCCCHHHHHH
LREHHSVYMVSSGRANVAGIDATRLDLLAEAIANVCK
HHHHCCEEEEECCCCCEECCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8108417; 10984043 [H]