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The map label for this gene is aprE [H]

Identifier: 77457687

GI number: 77457687

Start: 1631231

End: 1632592

Strand: Reverse

Name: aprE [H]

Synonym: Pfl01_1460

Alternate gene names: 77457687

Gene position: 1632592-1631231 (Counterclockwise)

Preceding gene: 77457688

Following gene: 77457684

Centisome position: 25.36

GC content: 61.45

Gene sequence:

>1362_bases
ATGTCTGCTTCCTCCTCTTCAAAACCGCGCGGTTACTTCGACAGTTTCGGCAAAAGCGCCGAGGCTGAATTCATGCCGGA
AACCGCCGGTGCCTCGCTGCAGGATTCGCCACGCTGGTCGCGCATCACCGTGTGGCTGGCGGCGGCGCTGCTGATCAGTG
CGCTGGTCTGGGCCAAGTTCGCGGTGCTGCAGGAAGTGACCATGGGCGAAGGCAAGGCGATTCCGTCGAGCAAGGTTCAG
GTGATCCAGAACCTCGAGGGCGGGATCGTCACCGAGATCTTCGTGCGCGAAGGGCAGATGGTCGACAAGGGCGACAAACT
GCTGCGCCTGGACGACACGCGGTTTCTGTCGAACAAGGGTGAGAGCGAGGCTGATCGTTATGCCTTGACCGCGCAGGTCG
AACGCTTGTCCGCCGAAGCCGAAGGCCGGCCATTCAAGCTCTCGGACGAAGTGATCGCCAAGGCCCCGCAAGTGGCCGAG
GACGAGCGTTCGCTGTACGAACAACGGCAGCGGCGGCTGGCCAGCGAGCAACGCACCCTCAGCGAACAGCTGCGGCAGAA
GACTCAGGAGCTGGCGGAGTTTCGCTCGAAACAGGGTCAGTACAGCTCAAGCCTGGCGTTGGTGAATCAGGAAATGAACA
TGTCCGAACCGCTGGTCAAGACTGGCGCCGTGTCGCCGGTGGAGATCCTGCGGCTCAAGCGCAGTGCCGTGGAAATCCGC
GGTTCCCTGAACGCCACGACCCTGGCCATTCCCCGCGCCGAATCGGCCATCGCCGAGATCCGCAGCAAGATCGACGAATC
GGAACAGACTTTCCGCTCGGAAGCGGCCAAGGAGCTCAATGAGAAACGTACCGACCTGTCGAAAATCACTGCTTCGAGCA
TCGCCATCGACGACCGCGTCAGCCGTACCACGGTGACCTCGCCGGTGCATGGGGTGATCAAGCAAATGAAGGTCAACACC
ATCGGCGGCGTGGTGCAGCCGGGCAGCGACATGGTGGAAATCGTGCCGCTGGAAGACAACCTGCTGATCGAAGCCAAAGT
CCGGCCGCAGGACGTGGCGTTCCTGCACCCGGGCCAGAAAGCCATGGTCAAGTTCAGCGCCTACGACTACACGATCTACG
GCGGGCTCAGTGCCAAACTTGAGCTGATCGGCGCTGACACCATCACCGACGACAAGGGCAACAGCTTCTACCTGATCCAG
GTGCGCACCGACAAAAACCACTTGGGCGGGGATGTGAAACCGCTGCTGATCATTCCGGGGATGGTGGCGACGGTGGACAT
CATTACCGGGGAGAAAAGCGTGCTGGATTACCTGCTAAAACCGGTGCTCAAGGCCCGGACCGAGGCGATGCGCGAGCGCT
AG

Upstream 100 bases:

>100_bases
CTGGACAACGGCCGGATCGTCGCCGACGGTCCGAAAGAAGCGGTCATCGATGCGCTGCGCAAGGGCCGGGTCGGCTCGGC
AGCGGTCTAGGAGTTGCCCC

Downstream 100 bases:

>100_bases
TGATGATCCGGACTTTGCGGTGAATTGATCGTTCCCACGCTCTGCGTGGGAACGATCAGGGCGAGTCCGATCGGTCTGAG
TCCGATCAGCCACCGTGATT

Product: Type I secretion membrane fusion protein, HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 452

Protein sequence:

>453_residues
MSASSSSKPRGYFDSFGKSAEAEFMPETAGASLQDSPRWSRITVWLAAALLISALVWAKFAVLQEVTMGEGKAIPSSKVQ
VIQNLEGGIVTEIFVREGQMVDKGDKLLRLDDTRFLSNKGESEADRYALTAQVERLSAEAEGRPFKLSDEVIAKAPQVAE
DERSLYEQRQRRLASEQRTLSEQLRQKTQELAEFRSKQGQYSSSLALVNQEMNMSEPLVKTGAVSPVEILRLKRSAVEIR
GSLNATTLAIPRAESAIAEIRSKIDESEQTFRSEAAKELNEKRTDLSKITASSIAIDDRVSRTTVTSPVHGVIKQMKVNT
IGGVVQPGSDMVEIVPLEDNLLIEAKVRPQDVAFLHPGQKAMVKFSAYDYTIYGGLSAKLELIGADTITDDKGNSFYLIQ
VRTDKNHLGGDVKPLLIIPGMVATVDIITGEKSVLDYLLKPVLKARTEAMRER

Sequences:

>Translated_453_residues
MSASSSSKPRGYFDSFGKSAEAEFMPETAGASLQDSPRWSRITVWLAAALLISALVWAKFAVLQEVTMGEGKAIPSSKVQ
VIQNLEGGIVTEIFVREGQMVDKGDKLLRLDDTRFLSNKGESEADRYALTAQVERLSAEAEGRPFKLSDEVIAKAPQVAE
DERSLYEQRQRRLASEQRTLSEQLRQKTQELAEFRSKQGQYSSSLALVNQEMNMSEPLVKTGAVSPVEILRLKRSAVEIR
GSLNATTLAIPRAESAIAEIRSKIDESEQTFRSEAAKELNEKRTDLSKITASSIAIDDRVSRTTVTSPVHGVIKQMKVNT
IGGVVQPGSDMVEIVPLEDNLLIEAKVRPQDVAFLHPGQKAMVKFSAYDYTIYGGLSAKLELIGADTITDDKGNSFYLIQ
VRTDKNHLGGDVKPLLIIPGMVATVDIITGEKSVLDYLLKPVLKARTEAMRER
>Mature_452_residues
SASSSSKPRGYFDSFGKSAEAEFMPETAGASLQDSPRWSRITVWLAAALLISALVWAKFAVLQEVTMGEGKAIPSSKVQV
IQNLEGGIVTEIFVREGQMVDKGDKLLRLDDTRFLSNKGESEADRYALTAQVERLSAEAEGRPFKLSDEVIAKAPQVAED
ERSLYEQRQRRLASEQRTLSEQLRQKTQELAEFRSKQGQYSSSLALVNQEMNMSEPLVKTGAVSPVEILRLKRSAVEIRG
SLNATTLAIPRAESAIAEIRSKIDESEQTFRSEAAKELNEKRTDLSKITASSIAIDDRVSRTTVTSPVHGVIKQMKVNTI
GGVVQPGSDMVEIVPLEDNLLIEAKVRPQDVAFLHPGQKAMVKFSAYDYTIYGGLSAKLELIGADTITDDKGNSFYLIQV
RTDKNHLGGDVKPLLIIPGMVATVDIITGEKSVLDYLLKPVLKARTEAMRER

Specific function: Involved in the secretion of alkaline protease [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 49892; Mature: 49760

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS00543 HLYD_FAMILY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASSSSKPRGYFDSFGKSAEAEFMPETAGASLQDSPRWSRITVWLAAALLISALVWAKF
CCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AVLQEVTMGEGKAIPSSKVQVIQNLEGGIVTEIFVREGQMVDKGDKLLRLDDTRFLSNKG
HHHHHHHCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCEECCCCCEEEECCCHHHCCCC
ESEADRYALTAQVERLSAEAEGRPFKLSDEVIAKAPQVAEDERSLYEQRQRRLASEQRTL
CCHHHHHHHHHHHHHHHHHCCCCCEECCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
SEQLRQKTQELAEFRSKQGQYSSSLALVNQEMNMSEPLVKTGAVSPVEILRLKRSAVEIR
HHHHHHHHHHHHHHHHHCCCCHHHHHEEECCCCCCCCHHHCCCCCHHHHHHHHHHHHHHH
GSLNATTLAIPRAESAIAEIRSKIDESEQTFRSEAAKELNEKRTDLSKITASSIAIDDRV
CCCCCEEEECCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCC
SRTTVTSPVHGVIKQMKVNTIGGVVQPGSDMVEIVPLEDNLLIEAKVRPQDVAFLHPGQK
CHHEECHHHHHHHHHHHHHHHCCEECCCCCCEEEEECCCCEEEEEECCCCCEEEECCCHH
AMVKFSAYDYTIYGGLSAKLELIGADTITDDKGNSFYLIQVRTDKNHLGGDVKPLLIIPG
HEEEEEEEEEEEECCCCEEEEEEECCEEECCCCCEEEEEEEECCCCCCCCCCCEEEEECC
MVATVDIITGEKSVLDYLLKPVLKARTEAMRER
HHHEEEEECCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SASSSSKPRGYFDSFGKSAEAEFMPETAGASLQDSPRWSRITVWLAAALLISALVWAKF
CCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AVLQEVTMGEGKAIPSSKVQVIQNLEGGIVTEIFVREGQMVDKGDKLLRLDDTRFLSNKG
HHHHHHHCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCEECCCCCEEEECCCHHHCCCC
ESEADRYALTAQVERLSAEAEGRPFKLSDEVIAKAPQVAEDERSLYEQRQRRLASEQRTL
CCHHHHHHHHHHHHHHHHHCCCCCEECCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
SEQLRQKTQELAEFRSKQGQYSSSLALVNQEMNMSEPLVKTGAVSPVEILRLKRSAVEIR
HHHHHHHHHHHHHHHHHCCCCHHHHHEEECCCCCCCCHHHCCCCCHHHHHHHHHHHHHHH
GSLNATTLAIPRAESAIAEIRSKIDESEQTFRSEAAKELNEKRTDLSKITASSIAIDDRV
CCCCCEEEECCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCC
SRTTVTSPVHGVIKQMKVNTIGGVVQPGSDMVEIVPLEDNLLIEAKVRPQDVAFLHPGQK
CHHEECHHHHHHHHHHHHHHHCCEECCCCCCEEEEECCCCEEEEEECCCCCEEEECCCHH
AMVKFSAYDYTIYGGLSAKLELIGADTITDDKGNSFYLIQVRTDKNHLGGDVKPLLIIPG
HEEEEEEEEEEEECCCCEEEEEEECCEEECCCCCEEEEEEEECCCCCCCCCCCEEEEECC
MVATVDIITGEKSVLDYLLKPVLKARTEAMRER
HHHEEEEECCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1427098; 10984043 [H]