Click here to switch to the map view.

The map label for this gene is pcpR [H]

Identifier: 77457612

GI number: 77457612

Start: 1557571

End: 1558506

Strand: Reverse

Name: pcpR [H]

Synonym: Pfl01_1385

Alternate gene names: 77457612

Gene position: 1558506-1557571 (Counterclockwise)

Preceding gene: 77457613

Following gene: 77457605

Centisome position: 24.21

GC content: 58.97

Gene sequence:

>936_bases
ATGCTGAACAGTAACTTGCTTAGAAAGCTCGACATGCAGGATCTCATGGTGTTTGTCGCCGTGTATGAGCAAAGCAGCGT
CACCGACGTGTCGGAGGCGCTGTTCGTCAGCCAGTCCACCGTCAGTTACTGCCTGAAAAAACTGCGCACCAGTTTTGAGG
ACGAGTTGTTCGTCAACACCCGCACGGGCATGCGCCCGACCTACAAGGCCAGCAGCATGTACGGCCATGTGCAGAAAATC
CTCGAAAGCATCAACCTGTGCCACGCCGGCGCCCCGACCTTCGACCCGATGGCGCAACCGGTGACCTTCAACATCTGCGC
CCCGGAATACTTCGAACAACTGATCCTGCCGCGAATGTTGAAACGCTTCGACTTCGATGACTTACCGGTGATGGTCAACA
TGCACAAGTTCGAAACCGACGTGCCGATCGAAGAGTTGCGCGACGGCAGTCTCGATCTGGTGATCTGTTTCGGTCCGAAC
TTCCATCGCAGTCACGCCGACCTGAAATCACGCATGCTGTTGGAAGATGACCTGGTCTGCGTCTTCGACAAACGCGCCAC
ACCGCTTGAGCCGCGCCTCAGCCTGCAAGCCTTCACCGAACGCCGGCATGTGTTCCCGACACCGTGGACGTCGACCACCA
ACATGGTCGACGGCTGGCTGGCGCGCCAGGCGCAGAAACGCCAGATCGTCGCCCGTTCAAACAGTTACAGCGCGGCGTTG
AAGATGATCACCGGCACCGATTTCATCCTGACCCTGCCCCGGCGCATTCAGCGTTTGCTGACCAACGACGCGGTGTTCAA
TCACTGCGAGGCGCCGAACGGTCTGCCGGGGTTCACCCTCGACATGCAGTGGAGCCACAACGTCGATCAGGACAGCGCCA
ACCTCTGGTTGCGCGAGCAGGTCATCAAGACCTGCGCGGAGCTGGAAGCGGCCTGA

Upstream 100 bases:

>100_bases
AAACGTCCTACAGGGCTTTCTCCTGGCACCATCGTTCCGTTACGATCATGCGCACACGTTTGCGCGGATTCGGCGCAAGG
AGCACAGCGAGACGGAACGG

Downstream 100 bases:

>100_bases
GTCCTACACGCCGATGGCGACTTTGCTGTAGGACTCGCGGTCGATGTCGAGCAGTTCCACACTCAACTGCACCTCGACCC
CGGCCGGCCATTCGCACAAT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MLNSNLLRKLDMQDLMVFVAVYEQSSVTDVSEALFVSQSTVSYCLKKLRTSFEDELFVNTRTGMRPTYKASSMYGHVQKI
LESINLCHAGAPTFDPMAQPVTFNICAPEYFEQLILPRMLKRFDFDDLPVMVNMHKFETDVPIEELRDGSLDLVICFGPN
FHRSHADLKSRMLLEDDLVCVFDKRATPLEPRLSLQAFTERRHVFPTPWTSTTNMVDGWLARQAQKRQIVARSNSYSAAL
KMITGTDFILTLPRRIQRLLTNDAVFNHCEAPNGLPGFTLDMQWSHNVDQDSANLWLREQVIKTCAELEAA

Sequences:

>Translated_311_residues
MLNSNLLRKLDMQDLMVFVAVYEQSSVTDVSEALFVSQSTVSYCLKKLRTSFEDELFVNTRTGMRPTYKASSMYGHVQKI
LESINLCHAGAPTFDPMAQPVTFNICAPEYFEQLILPRMLKRFDFDDLPVMVNMHKFETDVPIEELRDGSLDLVICFGPN
FHRSHADLKSRMLLEDDLVCVFDKRATPLEPRLSLQAFTERRHVFPTPWTSTTNMVDGWLARQAQKRQIVARSNSYSAAL
KMITGTDFILTLPRRIQRLLTNDAVFNHCEAPNGLPGFTLDMQWSHNVDQDSANLWLREQVIKTCAELEAA
>Mature_311_residues
MLNSNLLRKLDMQDLMVFVAVYEQSSVTDVSEALFVSQSTVSYCLKKLRTSFEDELFVNTRTGMRPTYKASSMYGHVQKI
LESINLCHAGAPTFDPMAQPVTFNICAPEYFEQLILPRMLKRFDFDDLPVMVNMHKFETDVPIEELRDGSLDLVICFGPN
FHRSHADLKSRMLLEDDLVCVFDKRATPLEPRLSLQAFTERRHVFPTPWTSTTNMVDGWLARQAQKRQIVARSNSYSAAL
KMITGTDFILTLPRRIQRLLTNDAVFNHCEAPNGLPGFTLDMQWSHNVDQDSANLWLREQVIKTCAELEAA

Specific function: Transcriptional activator for the pcpA, pcpB and pcpE genes for pentachlorophenol (PCP) degradation. Essential for PCP degradation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=309, Percent_Identity=22.6537216828479, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1787601, Length=251, Percent_Identity=23.9043824701195, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35592; Mature: 35592

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNSNLLRKLDMQDLMVFVAVYEQSSVTDVSEALFVSQSTVSYCLKKLRTSFEDELFVNT
CCCCHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
RTGMRPTYKASSMYGHVQKILESINLCHAGAPTFDPMAQPVTFNICAPEYFEQLILPRML
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHH
KRFDFDDLPVMVNMHKFETDVPIEELRDGSLDLVICFGPNFHRSHADLKSRMLLEDDLVC
HHCCCCCCCEEEEEECCCCCCCHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCEEE
VFDKRATPLEPRLSLQAFTERRHVFPTPWTSTTNMVDGWLARQAQKRQIVARSNSYSAAL
EECCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHH
KMITGTDFILTLPRRIQRLLTNDAVFNHCEAPNGLPGFTLDMQWSHNVDQDSANLWLREQ
HHHCCCHHEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHH
VIKTCAELEAA
HHHHHHHHCCC
>Mature Secondary Structure
MLNSNLLRKLDMQDLMVFVAVYEQSSVTDVSEALFVSQSTVSYCLKKLRTSFEDELFVNT
CCCCHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
RTGMRPTYKASSMYGHVQKILESINLCHAGAPTFDPMAQPVTFNICAPEYFEQLILPRML
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHH
KRFDFDDLPVMVNMHKFETDVPIEELRDGSLDLVICFGPNFHRSHADLKSRMLLEDDLVC
HHCCCCCCCEEEEEECCCCCCCHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCEEE
VFDKRATPLEPRLSLQAFTERRHVFPTPWTSTTNMVDGWLARQAQKRQIVARSNSYSAAL
EECCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHH
KMITGTDFILTLPRRIQRLLTNDAVFNHCEAPNGLPGFTLDMQWSHNVDQDSANLWLREQ
HHHCCCHHEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHH
VIKTCAELEAA
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12169590 [H]