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The map label for this gene is livM [H]

Identifier: 77457473

GI number: 77457473

Start: 1415990

End: 1417246

Strand: Reverse

Name: livM [H]

Synonym: Pfl01_1246

Alternate gene names: 77457473

Gene position: 1417246-1415990 (Counterclockwise)

Preceding gene: 77457474

Following gene: 77457472

Centisome position: 22.01

GC content: 61.26

Gene sequence:

>1257_bases
ATGACTAGGAATCTTAAACAGGCGTTGTTCAGCGCCTTGCTGGTCTGGGCCGTGGCCTATCCGGTACTGGGCCTGAAACT
GACTATCGTCGGCACCAATCTGGAAGTACACAACACCAGCCCGGCCATTCTGGCGACCATCGCCATCTGCTCGGTGCTGA
TGTTTCTGCGGGTGCTGTTCAACCAGCAGATCAGCAAGGCGTGGCGTTCGTCGCCGGGCATGCCGCTGATCCCGGCCAAG
GCCAGCAACTTCCTGACCCTGCCGACCACCCAGCGCTACTTCATCATCGCGCTGATCATCGGTGCGCTGGTGTGGCCGTT
CTTCGGCTCCCGCGGCGCAGTGGATATCGCGACGCTGATCCTGATCTACGTGATGCTCGGCCTGGGCCTGAACATCGTGG
TCGGCCTCGCCGGTCTGCTCGATCTGGGTTACGTCGGCTTCTACGCCGTCGGCGCCTACAGCTACGCGCTGCTGTCGCAC
TACTACGGCCTGAGCTTCTGGATCTGCCTGCCGATTGCCGGCCTGATGGCGGCGACGTTCGGCTTCCTGCTCGGCTTCCC
GGTGTTGCGTCTGCGCGGCGACTACCTGGCGATCGTGACCCTCGGTTTCGGGGAAATCATCCGCCTGTTCCTGCGTAACC
TGACCGACATCACCGGTGGTCCGAACGGGATCAGCAACATCGAGAAACCGACGTTCTTCGGCCTGACCTTCGAACGCAAG
GCCGCGGAAGGCCTGCAAACCTTCCATGAGTATTTCGGCCTGGAATACAACTCGATCAACAAGGTGATTTTCCTCTACCT
GGTTGCCCTGCTGCTGGCGCTGGCCGCACTGTTCATCATCAACCGCCTGCTGCGCATGCCGATCGGCCGTGCGTGGGAAG
CGCTGCGTGAAGATGAAATCGCCTGCCGTGCGCTGGGTCTCAACCCGACCGTGATCAAGCTCTCGGCGTTCACCCTGGGT
GCGAGCTTCGCCGGTTTCGCCGGCAGCTTCTTCGCCGCCCGTCAGGGTCTGGTGACGCCGGAGTCGTTCACCTTCATCGA
GTCGGCGATCATCCTCGCCATCGTGGTGCTGGGAGGCATGGGCTCGCAGCTGGGCGTGATTCTCGCGGCCGTGGTGATGA
TCCTGCTGCCGGAAATGATGCGTGAGTTCAGTGAGTACCGCATGTTGATGTTCGGCGCCCTGATGGTGTTGATGATGATC
TGGCGTCCACAAGGTCTGCTGCCGATGCAACGCCCACACATGGAGTTGCGCAAATGA

Upstream 100 bases:

>100_bases
TCGGCGACCAATACAAGGACGTCGTGGCTTTCGGCTTGTTGGTTCTGGTGCTGTTGTTCCGTCCGACCGGCATTCTGGGC
CGTCCGGAGGTTGAGAAAGT

Downstream 100 bases:

>100_bases
GCCGCGAGATCCTTAAAGTCGAAAACTTGAGCATGCGCTTCGGCGGCTTGCTGGCGGTCAACGGCGTGGCCCTGACCGTC
AAGGAAAAACAGGTGGTGGC

Product: leucine/isoleucine/valine transporter permease subunit

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 417

Protein sequence:

>418_residues
MTRNLKQALFSALLVWAVAYPVLGLKLTIVGTNLEVHNTSPAILATIAICSVLMFLRVLFNQQISKAWRSSPGMPLIPAK
ASNFLTLPTTQRYFIIALIIGALVWPFFGSRGAVDIATLILIYVMLGLGLNIVVGLAGLLDLGYVGFYAVGAYSYALLSH
YYGLSFWICLPIAGLMAATFGFLLGFPVLRLRGDYLAIVTLGFGEIIRLFLRNLTDITGGPNGISNIEKPTFFGLTFERK
AAEGLQTFHEYFGLEYNSINKVIFLYLVALLLALAALFIINRLLRMPIGRAWEALREDEIACRALGLNPTVIKLSAFTLG
ASFAGFAGSFFAARQGLVTPESFTFIESAIILAIVVLGGMGSQLGVILAAVVMILLPEMMREFSEYRMLMFGALMVLMMI
WRPQGLLPMQRPHMELRK

Sequences:

>Translated_418_residues
MTRNLKQALFSALLVWAVAYPVLGLKLTIVGTNLEVHNTSPAILATIAICSVLMFLRVLFNQQISKAWRSSPGMPLIPAK
ASNFLTLPTTQRYFIIALIIGALVWPFFGSRGAVDIATLILIYVMLGLGLNIVVGLAGLLDLGYVGFYAVGAYSYALLSH
YYGLSFWICLPIAGLMAATFGFLLGFPVLRLRGDYLAIVTLGFGEIIRLFLRNLTDITGGPNGISNIEKPTFFGLTFERK
AAEGLQTFHEYFGLEYNSINKVIFLYLVALLLALAALFIINRLLRMPIGRAWEALREDEIACRALGLNPTVIKLSAFTLG
ASFAGFAGSFFAARQGLVTPESFTFIESAIILAIVVLGGMGSQLGVILAAVVMILLPEMMREFSEYRMLMFGALMVLMMI
WRPQGLLPMQRPHMELRK
>Mature_417_residues
TRNLKQALFSALLVWAVAYPVLGLKLTIVGTNLEVHNTSPAILATIAICSVLMFLRVLFNQQISKAWRSSPGMPLIPAKA
SNFLTLPTTQRYFIIALIIGALVWPFFGSRGAVDIATLILIYVMLGLGLNIVVGLAGLLDLGYVGFYAVGAYSYALLSHY
YGLSFWICLPIAGLMAATFGFLLGFPVLRLRGDYLAIVTLGFGEIIRLFLRNLTDITGGPNGISNIEKPTFFGLTFERKA
AEGLQTFHEYFGLEYNSINKVIFLYLVALLLALAALFIINRLLRMPIGRAWEALREDEIACRALGLNPTVIKLSAFTLGA
SFAGFAGSFFAARQGLVTPESFTFIESAIILAIVVLGGMGSQLGVILAAVVMILLPEMMREFSEYRMLMFGALMVLMMIW
RPQGLLPMQRPHMELRK

Specific function: Component of the high affinity leucine, isoleucine, valine, transport system (LIV-I), which is operative without Na(+) and is specific for alanine and threonine, in addition to branched-chain amino acids [H]

COG id: COG4177

COG function: function code E; ABC-type branched-chain amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789865, Length=417, Percent_Identity=61.1510791366906, Blast_Score=461, Evalue=1e-131,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851
- InterPro:   IPR021807 [H]

Pfam domain/function: PF02653 BPD_transp_2; PF11862 DUF3382 [H]

EC number: NA

Molecular weight: Translated: 45944; Mature: 45813

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRNLKQALFSALLVWAVAYPVLGLKLTIVGTNLEVHNTSPAILATIAICSVLMFLRVLF
CCCHHHHHHHHHHHHHHHHHHHHCEEEEEEECCEEEECCCHHHHHHHHHHHHHHHHHHHH
NQQISKAWRSSPGMPLIPAKASNFLTLPTTQRYFIIALIIGALVWPFFGSRGAVDIATLI
HHHHHHHHHCCCCCCEECCCCCCEEECCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
LIYVMLGLGLNIVVGLAGLLDLGYVGFYAVGAYSYALLSHYYGLSFWICLPIAGLMAATF
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GFLLGFPVLRLRGDYLAIVTLGFGEIIRLFLRNLTDITGGPNGISNIEKPTFFGLTFERK
HHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECEEEHHH
AAEGLQTFHEYFGLEYNSINKVIFLYLVALLLALAALFIINRLLRMPIGRAWEALREDEI
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
ACRALGLNPTVIKLSAFTLGASFAGFAGSFFAARQGLVTPESFTFIESAIILAIVVLGGM
HHHEECCCCCEEEEEHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCC
GSQLGVILAAVVMILLPEMMREFSEYRMLMFGALMVLMMIWRPQGLLPMQRPHMELRK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCC
>Mature Secondary Structure 
TRNLKQALFSALLVWAVAYPVLGLKLTIVGTNLEVHNTSPAILATIAICSVLMFLRVLF
CCHHHHHHHHHHHHHHHHHHHHCEEEEEEECCEEEECCCHHHHHHHHHHHHHHHHHHHH
NQQISKAWRSSPGMPLIPAKASNFLTLPTTQRYFIIALIIGALVWPFFGSRGAVDIATLI
HHHHHHHHHCCCCCCEECCCCCCEEECCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
LIYVMLGLGLNIVVGLAGLLDLGYVGFYAVGAYSYALLSHYYGLSFWICLPIAGLMAATF
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GFLLGFPVLRLRGDYLAIVTLGFGEIIRLFLRNLTDITGGPNGISNIEKPTFFGLTFERK
HHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECEEEHHH
AAEGLQTFHEYFGLEYNSINKVIFLYLVALLLALAALFIINRLLRMPIGRAWEALREDEI
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
ACRALGLNPTVIKLSAFTLGASFAGFAGSFFAARQGLVTPESFTFIESAIILAIVVLGGM
HHHEECCCCCEEEEEHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCC
GSQLGVILAAVVMILLPEMMREFSEYRMLMFGALMVLMMIWRPQGLLPMQRPHMELRK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2120183; 10984043 [H]