Click here to switch to the map view.

The map label for this gene is cidA1 [H]

Identifier: 77457126

GI number: 77457126

Start: 1042724

End: 1043110

Strand: Direct

Name: cidA1 [H]

Synonym: Pfl01_0899

Alternate gene names: 77457126

Gene position: 1042724-1043110 (Clockwise)

Preceding gene: 77457124

Following gene: 77457127

Centisome position: 16.2

GC content: 62.27

Gene sequence:

>387_bases
ATGAAAGCCTCGACCCTCAAATACCTCTCTCGCCTGCTGGCCGAACTGGCCGTGCTGCTCGCTTTTTACCTGCTCGGCTG
CCAGATCGCAGCGTGGCTGGCCTGGCCGATTCCCGGCGGCGTGATCGGCATGGCGCTATTGCTGCTGGGCTTTGCGTTCG
GCTGGATTAAACCGGCGGCGCTGCAAATGGGCGCCGGCCTGTTGATGGCCGAGATGCTGCTGTTCTTCATTCCCGCGCTG
ATGAGCCTGCTGGATTACGGCGCGTTGTTGCGTGACGACGGTTGGCGGATTCTGCTGGTGATCGCCGCCAGTACGTTGAT
GGTGATGCTGGTGACCGCGTTCGCAGTAGAGCTGGCCGTGCGCCTGAGGCGGTCCCATGAAGCTTGA

Upstream 100 bases:

>100_bases
TCCATGGCCTGATTCCAGATTGGAATGGCTTTGAGTCTAACAATTCGCTTCGGAGATGGTAGCCGGGTTCGTAAGATAGC
CACCTGAAAGGAGCCCATCG

Downstream 100 bases:

>100_bases
GCTGATGCCGATGTTCTGGCTGGCGTTCACGTTGCTGGCCTACCTGTTCAGTCGCTGGCTGTATCGCCGGACCGGGCGTT
ACGTGCTGTCGCCACTGATT

Product: LrgA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 128; Mature: 128

Protein sequence:

>128_residues
MKASTLKYLSRLLAELAVLLAFYLLGCQIAAWLAWPIPGGVIGMALLLLGFAFGWIKPAALQMGAGLLMAEMLLFFIPAL
MSLLDYGALLRDDGWRILLVIAASTLMVMLVTAFAVELAVRLRRSHEA

Sequences:

>Translated_128_residues
MKASTLKYLSRLLAELAVLLAFYLLGCQIAAWLAWPIPGGVIGMALLLLGFAFGWIKPAALQMGAGLLMAEMLLFFIPAL
MSLLDYGALLRDDGWRILLVIAASTLMVMLVTAFAVELAVRLRRSHEA
>Mature_128_residues
MKASTLKYLSRLLAELAVLLAFYLLGCQIAAWLAWPIPGGVIGMALLLLGFAFGWIKPAALQMGAGLLMAEMLLFFIPAL
MSLLDYGALLRDDGWRILLVIAASTLMVMLVTAFAVELAVRLRRSHEA

Specific function: Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. W

COG id: COG1380

COG function: function code R; Putative effector of murein hydrolase LrgA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CidA/LrgA family. CidA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005538 [H]

Pfam domain/function: PF03788 LrgA [H]

EC number: NA

Molecular weight: Translated: 13936; Mature: 13936

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
6.2 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
6.2 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKASTLKYLSRLLAELAVLLAFYLLGCQIAAWLAWPIPGGVIGMALLLLGFAFGWIKPAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
LQMGAGLLMAEMLLFFIPALMSLLDYGALLRDDGWRILLVIAASTLMVMLVTAFAVELAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RLRRSHEA
HHHHHCCC
>Mature Secondary Structure
MKASTLKYLSRLLAELAVLLAFYLLGCQIAAWLAWPIPGGVIGMALLLLGFAFGWIKPAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
LQMGAGLLMAEMLLFFIPALMSLLDYGALLRDDGWRILLVIAASTLMVMLVTAFAVELAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RLRRSHEA
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]