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The map label for this gene is yafC [H]

Identifier: 77456947

GI number: 77456947

Start: 846618

End: 847529

Strand: Direct

Name: yafC [H]

Synonym: Pfl01_0719

Alternate gene names: 77456947

Gene position: 846618-847529 (Clockwise)

Preceding gene: 77456946

Following gene: 77456948

Centisome position: 13.15

GC content: 62.17

Gene sequence:

>912_bases
GTGAAAGCCAGATCCGATGAGTTGCAGATTTTCGTCTGCGTGATCGAATGCGGTTCGATCTCCGCCGCCGCCGAGCAGGT
CGGACAGACGCCGTCGGCGGTCAGCCGCACGCTGTCGCGACTGGAAGCCAAGCTCGACACCACGCTGATCAACCGCACCA
CTCGGCGCATGGACCTGACCGAGGAGGGCAAGTATTTCTTCGAACAGGCCAAGCTGATCCTCGACCAGATGGATCAACTC
GAGGAGCGCCTGTCCTCGCGTCAGCAGACGCCATCAGGACGGCTGCGGATCAACGCCGCGTCGCCGTTCATGCTCCACGC
CATCGTGCCGTACATCGACGAATTCCGTCGGCTGTACCCGGACATCCAGCTCGAACTCAACAGCAACGACCTGATCATTG
ACCTGCTGGAGCAAAGCACCGACGTCGCCATCCGCATCGGCACCCTCGCCGATTCGACGTTGCATGCCCGGTCGCTGGGC
TGCAGTCCGCTGTTGATCGTCGCCAGTCCCGCATACCTTGAGAAACACGGTGCGCCGCGCGAAGTGGCCGATCTGAGCGA
ACACACGTTGCTCGGCTTCACCCAGAACGAAGGCCTCAACCAGTGGCCGTTGCGTTACGTGCACGGCGACCGCTGGCCGA
TCACTCCGGCGATCAGCGCCTCCAGCGGCGAGACGGTTCGCCATCTGGCGCTGGAGGGGCAGGGCATTGCCTGCCTCTCG
CATTTCATGACCATCGACGACATTCGTGCCGGGCGGCTGAAGGTGTTGCTGGCGGAATTCAACAGCGGTTATCGCCAGCC
GATCAACGCGGTGTACTACCGCAACTCGCAGCTGGCGCTGCGCATCCAGTGCTTCCTGGACTTCATCCAGAGCAAACTGG
CGGCTTACGCCAGCGCCGATTTCAAAGGCTGA

Upstream 100 bases:

>100_bases
CGAGCAGCATCTGACCGAGGTGTTTGGCCTCAAGGCCTGACGCTCGGCTACTATCGAAGGCCTTAGCTTGCGCAGCAGGC
CTTTCGATTCGAGGACATCC

Downstream 100 bases:

>100_bases
TTCGTGACCTCTGCGCAACAGTGATTTGGTTGTGGGCGGGTTTTTCCACCGGGCTCGCCGGTCGATACTCGTTGCATCAC
TTATTCACGCAGGGAGTTTC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MKARSDELQIFVCVIECGSISAAAEQVGQTPSAVSRTLSRLEAKLDTTLINRTTRRMDLTEEGKYFFEQAKLILDQMDQL
EERLSSRQQTPSGRLRINAASPFMLHAIVPYIDEFRRLYPDIQLELNSNDLIIDLLEQSTDVAIRIGTLADSTLHARSLG
CSPLLIVASPAYLEKHGAPREVADLSEHTLLGFTQNEGLNQWPLRYVHGDRWPITPAISASSGETVRHLALEGQGIACLS
HFMTIDDIRAGRLKVLLAEFNSGYRQPINAVYYRNSQLALRIQCFLDFIQSKLAAYASADFKG

Sequences:

>Translated_303_residues
MKARSDELQIFVCVIECGSISAAAEQVGQTPSAVSRTLSRLEAKLDTTLINRTTRRMDLTEEGKYFFEQAKLILDQMDQL
EERLSSRQQTPSGRLRINAASPFMLHAIVPYIDEFRRLYPDIQLELNSNDLIIDLLEQSTDVAIRIGTLADSTLHARSLG
CSPLLIVASPAYLEKHGAPREVADLSEHTLLGFTQNEGLNQWPLRYVHGDRWPITPAISASSGETVRHLALEGQGIACLS
HFMTIDDIRAGRLKVLLAEFNSGYRQPINAVYYRNSQLALRIQCFLDFIQSKLAAYASADFKG
>Mature_303_residues
MKARSDELQIFVCVIECGSISAAAEQVGQTPSAVSRTLSRLEAKLDTTLINRTTRRMDLTEEGKYFFEQAKLILDQMDQL
EERLSSRQQTPSGRLRINAASPFMLHAIVPYIDEFRRLYPDIQLELNSNDLIIDLLEQSTDVAIRIGTLADSTLHARSLG
CSPLLIVASPAYLEKHGAPREVADLSEHTLLGFTQNEGLNQWPLRYVHGDRWPITPAISASSGETVRHLALEGQGIACLS
HFMTIDDIRAGRLKVLLAEFNSGYRQPINAVYYRNSQLALRIQCFLDFIQSKLAAYASADFKG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=289, Percent_Identity=46.0207612456747, Blast_Score=262, Evalue=2e-71,
Organism=Escherichia coli, GI87081978, Length=295, Percent_Identity=31.864406779661, Blast_Score=150, Evalue=7e-38,
Organism=Escherichia coli, GI1789639, Length=287, Percent_Identity=31.3588850174216, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI145693193, Length=297, Percent_Identity=31.986531986532, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1789440, Length=299, Percent_Identity=31.1036789297659, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1787128, Length=295, Percent_Identity=27.1186440677966, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1789173, Length=302, Percent_Identity=30.4635761589404, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787589, Length=295, Percent_Identity=26.1016949152542, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788706, Length=200, Percent_Identity=29, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788481, Length=286, Percent_Identity=23.7762237762238, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786508, Length=92, Percent_Identity=39.1304347826087, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI87082132, Length=250, Percent_Identity=26.8, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1787879, Length=239, Percent_Identity=26.3598326359833, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789492, Length=261, Percent_Identity=26.0536398467433, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786448, Length=185, Percent_Identity=25.9459459459459, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790262, Length=282, Percent_Identity=24.822695035461, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788748, Length=121, Percent_Identity=33.8842975206612, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33869; Mature: 33869

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKARSDELQIFVCVIECGSISAAAEQVGQTPSAVSRTLSRLEAKLDTTLINRTTRRMDLT
CCCCCCCEEEEEEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EEGKYFFEQAKLILDQMDQLEERLSSRQQTPSGRLRINAASPFMLHAIVPYIDEFRRLYP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCC
DIQLELNSNDLIIDLLEQSTDVAIRIGTLADSTLHARSLGCSPLLIVASPAYLEKHGAPR
CEEEEECCCCEEEEEECCCCCEEEEEECCCCCHHHHHHCCCCEEEEEECCHHHHHCCCCH
EVADLSEHTLLGFTQNEGLNQWPLRYVHGDRWPITPAISASSGETVRHLALEGQGIACLS
HHHHCCCCEEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHH
HFMTIDDIRAGRLKVLLAEFNSGYRQPINAVYYRNSQLALRIQCFLDFIQSKLAAYASAD
HHHHHHHCCCCHHEEEEEHHCCCCCCCCCEEEEECCCCEEHHHHHHHHHHHHHHHHHCCC
FKG
CCC
>Mature Secondary Structure
MKARSDELQIFVCVIECGSISAAAEQVGQTPSAVSRTLSRLEAKLDTTLINRTTRRMDLT
CCCCCCCEEEEEEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EEGKYFFEQAKLILDQMDQLEERLSSRQQTPSGRLRINAASPFMLHAIVPYIDEFRRLYP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCC
DIQLELNSNDLIIDLLEQSTDVAIRIGTLADSTLHARSLGCSPLLIVASPAYLEKHGAPR
CEEEEECCCCEEEEEECCCCCEEEEEECCCCCHHHHHHCCCCEEEEEECCHHHHHCCCCH
EVADLSEHTLLGFTQNEGLNQWPLRYVHGDRWPITPAISASSGETVRHLALEGQGIACLS
HHHHCCCCEEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHH
HFMTIDDIRAGRLKVLLAEFNSGYRQPINAVYYRNSQLALRIQCFLDFIQSKLAAYASAD
HHHHHHHCCCCHHEEEEEHHCCCCCCCCCEEEEECCCCEEHHHHHHHHHHHHHHHHHCCC
FKG
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]