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The map label for this gene is mdtP [H]

Identifier: 77456936

GI number: 77456936

Start: 839060

End: 840511

Strand: Direct

Name: mdtP [H]

Synonym: Pfl01_0708

Alternate gene names: 77456936

Gene position: 839060-840511 (Clockwise)

Preceding gene: 77456935

Following gene: 77456937

Centisome position: 13.03

GC content: 61.16

Gene sequence:

>1452_bases
ATGCATTCGATTACACGTTTGATGCTGGCGCCGCTGGCGTCGTCCATCCTGTTGGCGGCCGGTTGTGTGAACTACGCCGG
GATCGATCATCAGGGCAAATTGCTGGCGGTCGGCGATGCACCGTCCGACAGCCTGAAAGACAAGCTGCCGCCGGCCCAAT
GGCCGCGTGCGGACTGGTGGACATCGCTGGGTGATCCACGTCTGGGTGCTCTGATCGAAGAGGCTTATGCCAGCAACCCG
GACTTGCAGGAAGTCGCTGCCCGGGTCGCGAAAGCCAACGCATTTCTCGACCTGCGCGACGCCGAGCGTTATCCGGAAAT
GGACGCGTCGGCGGGTGTCACTCGCGGTCGGCTGTCGCGCTTTGAGGACTACAGCGGCGAGGGCCACCAGTACTTCACTG
CGCGTAATCTGGCGGTCAATTTCAGCTATACCTTCGACCTCTGGGGCGGCCAGCGTGCCGCCTGGGAATCGGCGCTCAAC
AGCGCACGAGCGGCGGAAGTCGATCTGCAATCGTCGCGGCTGATTCTCGCGGTCAACGTGGTCAAGGCTTACAACCAGTT
GGCCTATGCGTGGCAGGTCTCGGAGCTCAATCAACGGGATCTTGAACGCCTGAGCAAATTGGTGGAGCTGACGGATTCAC
GTTACGGCTCGGGCCTCGACAACCTGTCGCAACTCAAGCAGGTGCAGAGCCTCAAGGCGCGTTCGGAATCGACACTGATC
GGCGCTAACGAAGATATCGAAATTGCTCGTCTTCAACTGTCGGCGCTGATCGGCAAGGGCGTTGATCGTGCGCACACCCT
GGAGCGGCCATCGAATCTGCAAGCCAGTGTGGTGGCCTTGCCGGCGCAGTTGCCGGCCCAATTGTTGGGCCGTCGTCCGG
ACATCGTCGCCGCACGTTGGCGCGTGGAGGCCGAGACTAAAAACGTCGAGGCGGTGAAGACCACGTTCTACCCGAACATC
AATCTGGTGGCAGCGGCGGGTTCCCATGCTTTGACCGGCGATGCGCTGTTCGCCGGGGTCAGCAAGTTCTGGAATGTGGC
GCCGACGGTGTCGCTGCCGATCTTCGATGCCGGGCGCCTGCGCTCAGATCTCAAGGCCGGCAATGCCGAACTCGACAGCG
CCATCGCGCAGTACAACCGGGTGTTGAATTCGGCGCTGCATGAGGTGGCGATTTCGGTCACGCAGCTGCGTTCGTTCGAG
CAGCAGATCGTCGTGCAGCGCGATGCCTGTGCGATTGCCCAGTCGTCCTACGATCTGTCGCAGTCGCGCTACAAGGCCGG
GGAGGACACGTTTCTCGATGCGCTTAACATCGAGCAACAATTGATTCAGGACGAAATGCGTCTGGCTTTCCTCAACAGCA
AGCACATCGACAGTTCGGTTTCGTTGATGGCAGCGCTGGGCGGCGGGTTCCAGGCGCCTTCGCTGGAGACCGCGCAGAGC
AGCGATTTGTAG

Upstream 100 bases:

>100_bases
GCCGTCGGTGTACACGCTGCTCAGTTCGATCAAGCAACCGAGCCATGCACCCGAAGCCGAGCCGGCCGGTGTGCCGCAAC
CCATCCTGTGAGGACGTGAC

Downstream 100 bases:

>100_bases
TTGTTTTGCGGGACGCCGCCTCCGGGGCGGCTGTCGCGGGGAAAAAACATCTTGTGTATAGTCTTACTGTTCTCGTATAG
ACGAATACAAGCCGGATTTT

Product: RND efflux system outer membrane lipoprotein NodT

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MHSITRLMLAPLASSILLAAGCVNYAGIDHQGKLLAVGDAPSDSLKDKLPPAQWPRADWWTSLGDPRLGALIEEAYASNP
DLQEVAARVAKANAFLDLRDAERYPEMDASAGVTRGRLSRFEDYSGEGHQYFTARNLAVNFSYTFDLWGGQRAAWESALN
SARAAEVDLQSSRLILAVNVVKAYNQLAYAWQVSELNQRDLERLSKLVELTDSRYGSGLDNLSQLKQVQSLKARSESTLI
GANEDIEIARLQLSALIGKGVDRAHTLERPSNLQASVVALPAQLPAQLLGRRPDIVAARWRVEAETKNVEAVKTTFYPNI
NLVAAAGSHALTGDALFAGVSKFWNVAPTVSLPIFDAGRLRSDLKAGNAELDSAIAQYNRVLNSALHEVAISVTQLRSFE
QQIVVQRDACAIAQSSYDLSQSRYKAGEDTFLDALNIEQQLIQDEMRLAFLNSKHIDSSVSLMAALGGGFQAPSLETAQS
SDL

Sequences:

>Translated_483_residues
MHSITRLMLAPLASSILLAAGCVNYAGIDHQGKLLAVGDAPSDSLKDKLPPAQWPRADWWTSLGDPRLGALIEEAYASNP
DLQEVAARVAKANAFLDLRDAERYPEMDASAGVTRGRLSRFEDYSGEGHQYFTARNLAVNFSYTFDLWGGQRAAWESALN
SARAAEVDLQSSRLILAVNVVKAYNQLAYAWQVSELNQRDLERLSKLVELTDSRYGSGLDNLSQLKQVQSLKARSESTLI
GANEDIEIARLQLSALIGKGVDRAHTLERPSNLQASVVALPAQLPAQLLGRRPDIVAARWRVEAETKNVEAVKTTFYPNI
NLVAAAGSHALTGDALFAGVSKFWNVAPTVSLPIFDAGRLRSDLKAGNAELDSAIAQYNRVLNSALHEVAISVTQLRSFE
QQIVVQRDACAIAQSSYDLSQSRYKAGEDTFLDALNIEQQLIQDEMRLAFLNSKHIDSSVSLMAALGGGFQAPSLETAQS
SDL
>Mature_483_residues
MHSITRLMLAPLASSILLAAGCVNYAGIDHQGKLLAVGDAPSDSLKDKLPPAQWPRADWWTSLGDPRLGALIEEAYASNP
DLQEVAARVAKANAFLDLRDAERYPEMDASAGVTRGRLSRFEDYSGEGHQYFTARNLAVNFSYTFDLWGGQRAAWESALN
SARAAEVDLQSSRLILAVNVVKAYNQLAYAWQVSELNQRDLERLSKLVELTDSRYGSGLDNLSQLKQVQSLKARSESTLI
GANEDIEIARLQLSALIGKGVDRAHTLERPSNLQASVVALPAQLPAQLLGRRPDIVAARWRVEAETKNVEAVKTTFYPNI
NLVAAAGSHALTGDALFAGVSKFWNVAPTVSLPIFDAGRLRSDLKAGNAELDSAIAQYNRVLNSALHEVAISVTQLRSFE
QQIVVQRDACAIAQSSYDLSQSRYKAGEDTFLDALNIEQQLIQDEMRLAFLNSKHIDSSVSLMAALGGGFQAPSLETAQS
SDL

Specific function: Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI2367348, Length=492, Percent_Identity=27.8455284552846, Blast_Score=178, Evalue=5e-46,
Organism=Escherichia coli, GI1786785, Length=426, Percent_Identity=27.4647887323944, Blast_Score=142, Evalue=6e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 52598; Mature: 52598

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSITRLMLAPLASSILLAAGCVNYAGIDHQGKLLAVGDAPSDSLKDKLPPAQWPRADWW
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHCCCCCCCCCCHHH
TSLGDPRLGALIEEAYASNPDLQEVAARVAKANAFLDLRDAERYPEMDASAGVTRGRLSR
HCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEEEHHHHCCCCCCCCCCCCHHHHHH
FEDYSGEGHQYFTARNLAVNFSYTFDLWGGQRAAWESALNSARAAEVDLQSSRLILAVNV
HHCCCCCCCEEEEEEEEEEEEEEEEECCCCCHHHHHHHHHCCHHHEEECCCCCEEEEHHH
VKAYNQLAYAWQVSELNQRDLERLSKLVELTDSRYGSGLDNLSQLKQVQSLKARSESTLI
HHHHHHHHHEEEHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEE
GANEDIEIARLQLSALIGKGVDRAHTLERPSNLQASVVALPAQLPAQLLGRRPDIVAARW
CCCCCCHHHHHHHHHHHHCCCCHHHHCCCCCCCCEEEEEECHHHHHHHHCCCCCEEEEEE
RVEAETKNVEAVKTTFYPNINLVAAAGSHALTGDALFAGVSKFWNVAPTVSLPIFDAGRL
EEECCCCCCEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCHHH
RSDLKAGNAELDSAIAQYNRVLNSALHEVAISVTQLRSFEQQIVVQRDACAIAQSSYDLS
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
QSRYKAGEDTFLDALNIEQQLIQDEMRLAFLNSKHIDSSVSLMAALGGGFQAPSLETAQS
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCC
SDL
CCC
>Mature Secondary Structure
MHSITRLMLAPLASSILLAAGCVNYAGIDHQGKLLAVGDAPSDSLKDKLPPAQWPRADWW
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHCCCCCCCCCCHHH
TSLGDPRLGALIEEAYASNPDLQEVAARVAKANAFLDLRDAERYPEMDASAGVTRGRLSR
HCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEEEHHHHCCCCCCCCCCCCHHHHHH
FEDYSGEGHQYFTARNLAVNFSYTFDLWGGQRAAWESALNSARAAEVDLQSSRLILAVNV
HHCCCCCCCEEEEEEEEEEEEEEEEECCCCCHHHHHHHHHCCHHHEEECCCCCEEEEHHH
VKAYNQLAYAWQVSELNQRDLERLSKLVELTDSRYGSGLDNLSQLKQVQSLKARSESTLI
HHHHHHHHHEEEHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEE
GANEDIEIARLQLSALIGKGVDRAHTLERPSNLQASVVALPAQLPAQLLGRRPDIVAARW
CCCCCCHHHHHHHHHHHHCCCCHHHHCCCCCCCCEEEEEECHHHHHHHHCCCCCEEEEEE
RVEAETKNVEAVKTTFYPNINLVAAAGSHALTGDALFAGVSKFWNVAPTVSLPIFDAGRL
EEECCCCCCEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCHHH
RSDLKAGNAELDSAIAQYNRVLNSALHEVAISVTQLRSFEQQIVVQRDACAIAQSSYDLS
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
QSRYKAGEDTFLDALNIEQQLIQDEMRLAFLNSKHIDSSVSLMAALGGGFQAPSLETAQS
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCC
SDL
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]