Click here to switch to the map view.

The map label for this gene is recD [H]

Identifier: 77456918

GI number: 77456918

Start: 815535

End: 817643

Strand: Direct

Name: recD [H]

Synonym: Pfl01_0690

Alternate gene names: 77456918

Gene position: 815535-817643 (Clockwise)

Preceding gene: 77456917

Following gene: 77456919

Centisome position: 12.67

GC content: 62.35

Gene sequence:

>2109_bases
ATGAATCGGACATTCGCCGACCTGCTGCCTACGCCGCTGACCGCCGAAAGCCTCGCGCAATTGACACCCCTGACCCGTGC
CGATGATCTTTTGCTGTTGCTGACCCAATGGGTCGAGCGTGGCTGGTTGCGGGCACTGGACAAGGCATTCGTGGCCTTTC
TTCATGAGTTGGAATCCGATGTCGATCCGCTGGTGTTGCTCGCCGCCGCATTGACCAGTCACCAGCTCGGCCATGGTCAT
GTCTGCCTGGATCTGTTCGAAACCCTCAAGGCACCGGATTTTGCACTTTCCCTGCCGCCGGAGGGGGATGCGCAACCCGG
CGTGTTGCTGCTGCCATCGCAATTGCTCGAAACCCTCGACGGAGCGCACTGGTGCAAGGTGCTGGCCGGCAGTTCGCTGG
TGGCACTGGCCGCCGACGAGAGTGCGTCGGCTCAGGAGCGCCCACTGGTGTTGTCCGGCAAGCGTTTGTACTTGCGGCGC
TATTGGGCCTACGAGCGGCGTATCGACAGCGCACTGCGTCAGCGACTCGCGGAGCAGGAAGCGACACCACCCGATCTTGC
ACGCCGGCTGAACGAACTGTTCGATCCGGCCCAGCGTGCGGATGTCATCGACTGGCAGAAACTCGCCTGCGCCCTGGCCA
CCCGAGGTGCCTTCAGCATCATCACGGGTGGCCCGGGTACCGGCAAGACGACGACGGTGGTCCGTTTGCTGGCGTTGCTC
CAGGCACCTGCGGTCGAGGCGCATCAACCATTGCGCATAAGGCTCGCGGCGCCTACCGGAAAAGCGGCGGCGCGGCTGAC
CGAGTCCATCAGTCAGCAGGTGCAATCGCTGAAGGTCGCTGACAGCGTCCGGGAAAAAATCCCGACCGAGGTGACCACGG
TGCACCGCCTGCTCGGTAGTCGTCCCGGCACGCGGCACTTTCGCCACCATGCCGGTAACCGTCTGCCCCTGGACGTTCTG
GTGGTCGATGAAGCGTCCATGATCGACCTGGAAATGATGGCCAATCTGCTCGATGCCTTGCCGCCTCATGCCCGATTGGT
GTTGCTGGGCGACAAGGATCAACTTGCCTCCGTGGAGGCGGGTGCGGTGCTGGGAGATTTGTGCCGTGATGCCGAAGCTG
GTTGGTACAGTGCGCAGACCCGCCAGTGGCTGGAACAGGTGAGTGGCGAATCCCTGCAGGACAGCGGCTTGCACGAAGGC
ACTGACGGCTCGCATCCATTGGCCCAGCAAGTGGTGATGCTGCGACACTCGCGGCGTTTCGGCGAGGGCAGCGGCATCGG
TCAACTGGCGCGACGAGTGAATCAGCAACTCCCGGTCGAGGCTCGCCAGTTGCTGGAAGCCAAGACTCATGGCGATGTGT
TTTCTTTGCCACTCCACAATGAGCACGACCGTGAACTCGAGCACCTGGTGCTCGATGGGCACGCGAAAGGCCCTCACGGA
TATCGACACTATCTGAGCGTCTTGCGCGATCGACGTCCGGCGAGCGGAACGCCGCTCGAGAACCCGTGTTGGGTCGACTG
GGCACGTGACGTCCTGCGGGCCTTCGATACCTTCCAGTTGTTGTGCGCAGTGCGCAAAGGGCCGTGGGGTGTGGAGGGGC
TGAACCAGCGCATCACCGAAGCGTTGCTCAAGGCGCGGCTGATCGAGAGCGACCAGCAATGGTACGAAGGCCGGCCGGTG
CTGATGACCCGAAACGACTACGGTCTGGGGCTGATGAACGGTGACATCGGTATCGCCCTGAAACTGCCCGAGCGCGATGG
CCCTGATGCCGGTAAATCGGTATTGCGAGTGGCGTTCCCGCGTAACGACGGGCGCGGCGGGGTGCGTTTCGTGTTGCCGA
GCCGGCTCAACGATGTCGAGACCGTCTATGCGATGACCGTGCACAAGTCTCAGGGCTCGGAGTTTGCCCATACCGCGCTG
ATCCTGCCGGACGCCCTGAATCCTGTGTTGACCAAGGAACTGATCTATACCGGAATTACCCGGGCCAAGGACTGGTTCAC
CTTGATCGAGCCTCGGAGCGGCGTGTTTGAAGAAGCGGTGCAGCGCAAGGTGAAGCGCCTGAGTGGACTGATGCTGGAAC
TGGAAGAAGGCGCGCCGCATAAAGGATGA

Upstream 100 bases:

>100_bases
TCGCGCGACCACCAAGGGAGCTGATCGAGCGTCTGGACCTCATGTTCCAGGGCAAACCGCAACCCAAGGCCGAGCCCGCG
TGGGAACAGGGAGAGCTGCT

Downstream 100 bases:

>100_bases
AGGTGCCTTCGATTGCCGCCGATAATTGACCGACCGGTCAGAGGTCGCTGTATCGCTGGCTTTCCAACGCTGTGCTATCG
TTGCGGCATCATTTCGTAAC

Product: DNA helicase/exodeoxyribonuclease V subunit alpha

Products: NA

Alternate protein names: Exodeoxyribonuclease V 67 kDa polypeptide [H]

Number of amino acids: Translated: 702; Mature: 702

Protein sequence:

>702_residues
MNRTFADLLPTPLTAESLAQLTPLTRADDLLLLLTQWVERGWLRALDKAFVAFLHELESDVDPLVLLAAALTSHQLGHGH
VCLDLFETLKAPDFALSLPPEGDAQPGVLLLPSQLLETLDGAHWCKVLAGSSLVALAADESASAQERPLVLSGKRLYLRR
YWAYERRIDSALRQRLAEQEATPPDLARRLNELFDPAQRADVIDWQKLACALATRGAFSIITGGPGTGKTTTVVRLLALL
QAPAVEAHQPLRIRLAAPTGKAAARLTESISQQVQSLKVADSVREKIPTEVTTVHRLLGSRPGTRHFRHHAGNRLPLDVL
VVDEASMIDLEMMANLLDALPPHARLVLLGDKDQLASVEAGAVLGDLCRDAEAGWYSAQTRQWLEQVSGESLQDSGLHEG
TDGSHPLAQQVVMLRHSRRFGEGSGIGQLARRVNQQLPVEARQLLEAKTHGDVFSLPLHNEHDRELEHLVLDGHAKGPHG
YRHYLSVLRDRRPASGTPLENPCWVDWARDVLRAFDTFQLLCAVRKGPWGVEGLNQRITEALLKARLIESDQQWYEGRPV
LMTRNDYGLGLMNGDIGIALKLPERDGPDAGKSVLRVAFPRNDGRGGVRFVLPSRLNDVETVYAMTVHKSQGSEFAHTAL
ILPDALNPVLTKELIYTGITRAKDWFTLIEPRSGVFEEAVQRKVKRLSGLMLELEEGAPHKG

Sequences:

>Translated_702_residues
MNRTFADLLPTPLTAESLAQLTPLTRADDLLLLLTQWVERGWLRALDKAFVAFLHELESDVDPLVLLAAALTSHQLGHGH
VCLDLFETLKAPDFALSLPPEGDAQPGVLLLPSQLLETLDGAHWCKVLAGSSLVALAADESASAQERPLVLSGKRLYLRR
YWAYERRIDSALRQRLAEQEATPPDLARRLNELFDPAQRADVIDWQKLACALATRGAFSIITGGPGTGKTTTVVRLLALL
QAPAVEAHQPLRIRLAAPTGKAAARLTESISQQVQSLKVADSVREKIPTEVTTVHRLLGSRPGTRHFRHHAGNRLPLDVL
VVDEASMIDLEMMANLLDALPPHARLVLLGDKDQLASVEAGAVLGDLCRDAEAGWYSAQTRQWLEQVSGESLQDSGLHEG
TDGSHPLAQQVVMLRHSRRFGEGSGIGQLARRVNQQLPVEARQLLEAKTHGDVFSLPLHNEHDRELEHLVLDGHAKGPHG
YRHYLSVLRDRRPASGTPLENPCWVDWARDVLRAFDTFQLLCAVRKGPWGVEGLNQRITEALLKARLIESDQQWYEGRPV
LMTRNDYGLGLMNGDIGIALKLPERDGPDAGKSVLRVAFPRNDGRGGVRFVLPSRLNDVETVYAMTVHKSQGSEFAHTAL
ILPDALNPVLTKELIYTGITRAKDWFTLIEPRSGVFEEAVQRKVKRLSGLMLELEEGAPHKG
>Mature_702_residues
MNRTFADLLPTPLTAESLAQLTPLTRADDLLLLLTQWVERGWLRALDKAFVAFLHELESDVDPLVLLAAALTSHQLGHGH
VCLDLFETLKAPDFALSLPPEGDAQPGVLLLPSQLLETLDGAHWCKVLAGSSLVALAADESASAQERPLVLSGKRLYLRR
YWAYERRIDSALRQRLAEQEATPPDLARRLNELFDPAQRADVIDWQKLACALATRGAFSIITGGPGTGKTTTVVRLLALL
QAPAVEAHQPLRIRLAAPTGKAAARLTESISQQVQSLKVADSVREKIPTEVTTVHRLLGSRPGTRHFRHHAGNRLPLDVL
VVDEASMIDLEMMANLLDALPPHARLVLLGDKDQLASVEAGAVLGDLCRDAEAGWYSAQTRQWLEQVSGESLQDSGLHEG
TDGSHPLAQQVVMLRHSRRFGEGSGIGQLARRVNQQLPVEARQLLEAKTHGDVFSLPLHNEHDRELEHLVLDGHAKGPHG
YRHYLSVLRDRRPASGTPLENPCWVDWARDVLRAFDTFQLLCAVRKGPWGVEGLNQRITEALLKARLIESDQQWYEGRPV
LMTRNDYGLGLMNGDIGIALKLPERDGPDAGKSVLRVAFPRNDGRGGVRFVLPSRLNDVETVYAMTVHKSQGSEFAHTAL
ILPDALNPVLTKELIYTGITRAKDWFTLIEPRSGVFEEAVQRKVKRLSGLMLELEEGAPHKG

Specific function: Exhibits several catalytic activities, including ATP- dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent unwinding and DNA-dependent ATPase activities. Strand cleavage occurs 5' to 3' during the unwinding of duplex DNA at CHI sequences, whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recD family [H]

Homologues:

Organism=Escherichia coli, GI1789182, Length=659, Percent_Identity=42.4886191198786, Blast_Score=396, Evalue=1e-111,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007807
- InterPro:   IPR006344
- InterPro:   IPR000606 [H]

Pfam domain/function: PF05127 DUF699; PF01443 Viral_helicase1 [H]

EC number: =3.1.11.5 [H]

Molecular weight: Translated: 77448; Mature: 77448

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS00024 HEMOPEXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRTFADLLPTPLTAESLAQLTPLTRADDLLLLLTQWVERGWLRALDKAFVAFLHELESD
CCCCHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VDPLVLLAAALTSHQLGHGHVCLDLFETLKAPDFALSLPPEGDAQPGVLLLPSQLLETLD
CHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCCCEEECHHHHHHHHC
GAHWCKVLAGSSLVALAADESASAQERPLVLSGKRLYLRRYWAYERRIDSALRQRLAEQE
CHHHHHHHCCCCEEEEECCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHC
ATPPDLARRLNELFDPAQRADVIDWQKLACALATRGAFSIITGGPGTGKTTTVVRLLALL
CCCHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHH
QAPAVEAHQPLRIRLAAPTGKAAARLTESISQQVQSLKVADSVREKIPTEVTTVHRLLGS
HCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCC
RPGTRHFRHHAGNRLPLDVLVVDEASMIDLEMMANLLDALPPHARLVLLGDKDQLASVEA
CCCCHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHH
GAVLGDLCRDAEAGWYSAQTRQWLEQVSGESLQDSGLHEGTDGSHPLAQQVVMLRHSRRF
HHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHCC
GEGSGIGQLARRVNQQLPVEARQLLEAKTHGDVFSLPLHNEHDRELEHLVLDGHAKGPHG
CCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHEECCCCCCCCH
YRHYLSVLRDRRPASGTPLENPCWVDWARDVLRAFDTFQLLCAVRKGPWGVEGLNQRITE
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
ALLKARLIESDQQWYEGRPVLMTRNDYGLGLMNGDIGIALKLPERDGPDAGKSVLRVAFP
HHHHHHHHHCHHHHHCCCCEEEECCCCCCEEEECCEEEEEECCCCCCCCHHHHHEEEEEC
RNDGRGGVRFVLPSRLNDVETVYAMTVHKSQGSEFAHTALILPDALNPVLTKELIYTGIT
CCCCCCCEEEECCCCCCCHHHEEEEEEECCCCCCHHHHEEECCHHCCHHHHHHHHHHHHH
RAKDWFTLIEPRSGVFEEAVQRKVKRLSGLMLELEEGAPHKG
HCCCHHEEECCCCCHHHHHHHHHHHHHHHHEEEECCCCCCCC
>Mature Secondary Structure
MNRTFADLLPTPLTAESLAQLTPLTRADDLLLLLTQWVERGWLRALDKAFVAFLHELESD
CCCCHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VDPLVLLAAALTSHQLGHGHVCLDLFETLKAPDFALSLPPEGDAQPGVLLLPSQLLETLD
CHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCCCEEECHHHHHHHHC
GAHWCKVLAGSSLVALAADESASAQERPLVLSGKRLYLRRYWAYERRIDSALRQRLAEQE
CHHHHHHHCCCCEEEEECCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHC
ATPPDLARRLNELFDPAQRADVIDWQKLACALATRGAFSIITGGPGTGKTTTVVRLLALL
CCCHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHH
QAPAVEAHQPLRIRLAAPTGKAAARLTESISQQVQSLKVADSVREKIPTEVTTVHRLLGS
HCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCC
RPGTRHFRHHAGNRLPLDVLVVDEASMIDLEMMANLLDALPPHARLVLLGDKDQLASVEA
CCCCHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHH
GAVLGDLCRDAEAGWYSAQTRQWLEQVSGESLQDSGLHEGTDGSHPLAQQVVMLRHSRRF
HHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHCC
GEGSGIGQLARRVNQQLPVEARQLLEAKTHGDVFSLPLHNEHDRELEHLVLDGHAKGPHG
CCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHEECCCCCCCCH
YRHYLSVLRDRRPASGTPLENPCWVDWARDVLRAFDTFQLLCAVRKGPWGVEGLNQRITE
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
ALLKARLIESDQQWYEGRPVLMTRNDYGLGLMNGDIGIALKLPERDGPDAGKSVLRVAFP
HHHHHHHHHCHHHHHCCCCEEEECCCCCCEEEECCEEEEEECCCCCCCCHHHHHEEEEEC
RNDGRGGVRFVLPSRLNDVETVYAMTVHKSQGSEFAHTALILPDALNPVLTKELIYTGIT
CCCCCCCEEEECCCCCCCHHHEEEEEEECCCCCCHHHHEEECCHHCCHHHHHHHHHHHHH
RAKDWFTLIEPRSGVFEEAVQRKVKRLSGLMLELEEGAPHKG
HCCCHHEEECCCCCHHHHHHHHHHHHHHHHEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3537961; 9278503; 3537960 [H]