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The map label for this gene is speA [H]

Identifier: 77456855

GI number: 77456855

Start: 737398

End: 739311

Strand: Direct

Name: speA [H]

Synonym: Pfl01_0627

Alternate gene names: 77456855

Gene position: 737398-739311 (Clockwise)

Preceding gene: 77456854

Following gene: 77456856

Centisome position: 11.45

GC content: 61.6

Gene sequence:

>1914_bases
ATGTCCGTACGACGCACACGCAAAGACGATGGCAGCCAATGGACAGTTGCGGACAGCCGCAGTGTTTACGGGATTCGCCA
TTGGGGGGCCGGGTATTTCGCGATCAATGACGCCGGTCGCGTCGAAGTTCGTCCGAACGGCCCGAGCAGCTCGCCTATCG
ATCTGTTCGAACAAGTCGACCAGTTGCGCAAGAGTGGCTTGTCCCTGCCGCTGCTGGTGCGTTTCCCCGACATCCTGCAA
GACCGCGTCCGTCAGCTGACCGGCGCTTTCGATGCGAACATCGAGCGTCTGGAATACCAGAGCAAATACACCGCGCTGTA
CCCGATCAAGGTCAACCAGCAGGAAGCGGTGATCGAGAACATCATCGCCACCCAGAACGTTTCCATCGGTCTGGAAGCCG
GCTCCAAGCCTGAGCTGCTGGCGGTGCTGGCACTGGCGCCGAAGGGCGGCACCATCGTCTGCAACGGTTACAAGGACCGC
GAGTTCATCCGTCTGGCGCTGATGGGCCAGAAGCTCGGTCACAATGTGTTCATCGTGATCGAGAAAGAATCCGAAGTCGG
TCTGGTGATCGAAGAAGCCGCCTCGCTGAAGGTCAAGCCACAGGTCGGCCTGCGCGTGCGTCTGTCGTCCCTGGCGTCGT
CGAAGTGGGCGGACACCGGTGGCGAGAAATCCAAGTTCGGTCTGTCGGCGGCGCAACTGTTGTCGGTGGTCGAGCGCTTC
CGCGCGGCGGGTCTGGATCAGGGCATTCGTCTGCTGCACTTCCACATGGGTTCGCAGATCGCCAACCTGGCCGATTACCA
GCACGGTTTCAAGGAAGCGATCCGCTACTACGGCGAGTTGCGCAACCTCGGTCTGCCGGTCGATCACATCGACGTCGGCG
GCGGTCTGGGTGTGGACTACGACGGTACCCACTCGCGCAACGCCAGTTCGATCAACTACGACATGGACGACTACGCCGGT
GTCGTGGTCGGCATGCTCAAGGAGTTCTGCGACGCGCAGGCCCTGCCGCATCCGCACATCTTCTCCGAAAGCGGCCGCTC
GTTGACCGCGCACCACGCGATGCTGGTGGTGCAGGTGACCGACGTCGAGAAACACAACGACGACGTGCCGCAGATCGAGA
ACAAGGAAGCGCTGCCGGAAACCGTGCAGTGGCTGGTTGACCTGCTCGGCCCGACCGACATCGAAATGGTCACCGAGACC
TACTGGCGCGCCACTCACTACATGAGCGACGTGGCCGCCCAGTACGCCGACGGCAAACTGACCCTGGCCGAGAAAGCCCT
GGCCGAGCAGTGCTACTTCGCGGTGTGCCGTCGCCTGCACAACTCGCTGAAAGCGCGTCAGCGTTCGCACCGTCAGGTGC
TGGACGAACTCAACGACAAGCTGGCCGACAAGTACATCTGCAACTTCTCGGTGTTCCAGAGCCTGCCGGACACCTGGGCG
ATCGATCAGGTCCTGCCGATCATCCCGCTGCACCGTCTCGACGAAGAGCCGCTGCGTCGTGCCGTTCTGCAAGACCTGAC
CTGCGACTCCGACGGCAAGATCAACCAGTACGTCGACGAGCAGAGCATCGAGACCAGCCTGCCGGTGCATGCGCTGAACG
AAGGTGAAGACTACCTGCTGGGCGTGTTCCTGGTCGGCGCCTATCAGGAAATCCTCGGCGACATGCACAACCTGTTCGGT
GACACCGACTCGGTGAACATCTATCAGAACGCCGATGGCAGCGTGTACCACGCCGGCATTGAAACCCACGACACCATCGA
AGACATGCTGCGTTACGTGCACTTGTCGCCGGAAGAGCTGATGACCCACTACCGCGACAAGTGCGCCAGTGCCCGCATCA
GCGCCAGCGAGCGCACCCAGTTCCTCGATGCATTGCGCCTGGGTCTGACCCGCTCCTCCTACCTGTCTTCCTGA

Upstream 100 bases:

>100_bases
CGCGGTCTACCGCCGCGCTGACGAACCGTCATTTTCATTCTTTAGACTGCGCCGGCCTGAGATCAGGCGACGCACTATGA
CTTCTTTATAGGGGACTTCG

Downstream 100 bases:

>100_bases
GGCCAGGTTCCGCTTTCATCTGGTTGTCTGAAATTGTTCCGCTAACCGCGGACGTTTCAGATAACCGGGTGAGACGCTTC
TTTTTCTCTTCGCGAAACGG

Product: arginine decarboxylase

Products: NA

Alternate protein names: ADC [H]

Number of amino acids: Translated: 637; Mature: 636

Protein sequence:

>637_residues
MSVRRTRKDDGSQWTVADSRSVYGIRHWGAGYFAINDAGRVEVRPNGPSSSPIDLFEQVDQLRKSGLSLPLLVRFPDILQ
DRVRQLTGAFDANIERLEYQSKYTALYPIKVNQQEAVIENIIATQNVSIGLEAGSKPELLAVLALAPKGGTIVCNGYKDR
EFIRLALMGQKLGHNVFIVIEKESEVGLVIEEAASLKVKPQVGLRVRLSSLASSKWADTGGEKSKFGLSAAQLLSVVERF
RAAGLDQGIRLLHFHMGSQIANLADYQHGFKEAIRYYGELRNLGLPVDHIDVGGGLGVDYDGTHSRNASSINYDMDDYAG
VVVGMLKEFCDAQALPHPHIFSESGRSLTAHHAMLVVQVTDVEKHNDDVPQIENKEALPETVQWLVDLLGPTDIEMVTET
YWRATHYMSDVAAQYADGKLTLAEKALAEQCYFAVCRRLHNSLKARQRSHRQVLDELNDKLADKYICNFSVFQSLPDTWA
IDQVLPIIPLHRLDEEPLRRAVLQDLTCDSDGKINQYVDEQSIETSLPVHALNEGEDYLLGVFLVGAYQEILGDMHNLFG
DTDSVNIYQNADGSVYHAGIETHDTIEDMLRYVHLSPEELMTHYRDKCASARISASERTQFLDALRLGLTRSSYLSS

Sequences:

>Translated_637_residues
MSVRRTRKDDGSQWTVADSRSVYGIRHWGAGYFAINDAGRVEVRPNGPSSSPIDLFEQVDQLRKSGLSLPLLVRFPDILQ
DRVRQLTGAFDANIERLEYQSKYTALYPIKVNQQEAVIENIIATQNVSIGLEAGSKPELLAVLALAPKGGTIVCNGYKDR
EFIRLALMGQKLGHNVFIVIEKESEVGLVIEEAASLKVKPQVGLRVRLSSLASSKWADTGGEKSKFGLSAAQLLSVVERF
RAAGLDQGIRLLHFHMGSQIANLADYQHGFKEAIRYYGELRNLGLPVDHIDVGGGLGVDYDGTHSRNASSINYDMDDYAG
VVVGMLKEFCDAQALPHPHIFSESGRSLTAHHAMLVVQVTDVEKHNDDVPQIENKEALPETVQWLVDLLGPTDIEMVTET
YWRATHYMSDVAAQYADGKLTLAEKALAEQCYFAVCRRLHNSLKARQRSHRQVLDELNDKLADKYICNFSVFQSLPDTWA
IDQVLPIIPLHRLDEEPLRRAVLQDLTCDSDGKINQYVDEQSIETSLPVHALNEGEDYLLGVFLVGAYQEILGDMHNLFG
DTDSVNIYQNADGSVYHAGIETHDTIEDMLRYVHLSPEELMTHYRDKCASARISASERTQFLDALRLGLTRSSYLSS
>Mature_636_residues
SVRRTRKDDGSQWTVADSRSVYGIRHWGAGYFAINDAGRVEVRPNGPSSSPIDLFEQVDQLRKSGLSLPLLVRFPDILQD
RVRQLTGAFDANIERLEYQSKYTALYPIKVNQQEAVIENIIATQNVSIGLEAGSKPELLAVLALAPKGGTIVCNGYKDRE
FIRLALMGQKLGHNVFIVIEKESEVGLVIEEAASLKVKPQVGLRVRLSSLASSKWADTGGEKSKFGLSAAQLLSVVERFR
AAGLDQGIRLLHFHMGSQIANLADYQHGFKEAIRYYGELRNLGLPVDHIDVGGGLGVDYDGTHSRNASSINYDMDDYAGV
VVGMLKEFCDAQALPHPHIFSESGRSLTAHHAMLVVQVTDVEKHNDDVPQIENKEALPETVQWLVDLLGPTDIEMVTETY
WRATHYMSDVAAQYADGKLTLAEKALAEQCYFAVCRRLHNSLKARQRSHRQVLDELNDKLADKYICNFSVFQSLPDTWAI
DQVLPIIPLHRLDEEPLRRAVLQDLTCDSDGKINQYVDEQSIETSLPVHALNEGEDYLLGVFLVGAYQEILGDMHNLFGD
TDSVNIYQNADGSVYHAGIETHDTIEDMLRYVHLSPEELMTHYRDKCASARISASERTQFLDALRLGLTRSSYLSS

Specific function: Catalyzes the biosynthesis of agmatine from arginine [H]

COG id: COG1166

COG function: function code E; Arginine decarboxylase (spermidine biosynthesis)

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789307, Length=620, Percent_Identity=44.3548387096774, Blast_Score=540, Evalue=1e-154,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR002985
- InterPro:   IPR022643
- InterPro:   IPR022657
- InterPro:   IPR022644
- InterPro:   IPR000183 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 71060; Mature: 70929

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: PS00879 ODR_DC_2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVRRTRKDDGSQWTVADSRSVYGIRHWGAGYFAINDAGRVEVRPNGPSSSPIDLFEQVD
CCCCCCCCCCCCEEEEECCCCEEEEEECCCEEEEECCCCEEEECCCCCCCCHHHHHHHHH
QLRKSGLSLPLLVRFPDILQDRVRQLTGAFDANIERLEYQSKYTALYPIKVNQQEAVIEN
HHHHCCCCCEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEEEEEEECCHHHHHHH
IIATQNVSIGLEAGSKPELLAVLALAPKGGTIVCNGYKDREFIRLALMGQKLGHNVFIVI
HHHHCCCEEEECCCCCCCEEEEEEECCCCCEEEECCCCCHHHHHHHHHHHHHCCCEEEEE
EKESEVGLVIEEAASLKVKPQVGLRVRLSSLASSKWADTGGEKSKFGLSAAQLLSVVERF
ECCCCCCEEEECCCCEEECCCCCCEEEHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHH
RAAGLDQGIRLLHFHMGSQIANLADYQHGFKEAIRYYGELRNLGLPVDHIDVGGGLGVDY
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCC
DGTHSRNASSINYDMDDYAGVVVGMLKEFCDAQALPHPHIFSESGRSLTAHHAMLVVQVT
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEEEEEEE
DVEKHNDDVPQIENKEALPETVQWLVDLLGPTDIEMVTETYWRATHYMSDVAAQYADGKL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCE
TLAEKALAEQCYFAVCRRLHNSLKARQRSHRQVLDELNDKLADKYICNFSVFQSLPDTWA
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCC
IDQVLPIIPLHRLDEEPLRRAVLQDLTCDSDGKINQYVDEQSIETSLPVHALNEGEDYLL
HHHHHHHCCHHCCCHHHHHHHHHHHCCCCCCCCHHHHHCHHHHHCCCCCEECCCCCHHHH
GVFLVGAYQEILGDMHNLFGDTDSVNIYQNADGSVYHAGIETHDTIEDMLRYVHLSPEEL
HHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEECCCCCHHHHHHHHHHHCCCHHHH
MTHYRDKCASARISASERTQFLDALRLGLTRSSYLSS
HHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHCCC
>Mature Secondary Structure 
SVRRTRKDDGSQWTVADSRSVYGIRHWGAGYFAINDAGRVEVRPNGPSSSPIDLFEQVD
CCCCCCCCCCCEEEEECCCCEEEEEECCCEEEEECCCCEEEECCCCCCCCHHHHHHHHH
QLRKSGLSLPLLVRFPDILQDRVRQLTGAFDANIERLEYQSKYTALYPIKVNQQEAVIEN
HHHHCCCCCEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEEEEEEECCHHHHHHH
IIATQNVSIGLEAGSKPELLAVLALAPKGGTIVCNGYKDREFIRLALMGQKLGHNVFIVI
HHHHCCCEEEECCCCCCCEEEEEEECCCCCEEEECCCCCHHHHHHHHHHHHHCCCEEEEE
EKESEVGLVIEEAASLKVKPQVGLRVRLSSLASSKWADTGGEKSKFGLSAAQLLSVVERF
ECCCCCCEEEECCCCEEECCCCCCEEEHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHH
RAAGLDQGIRLLHFHMGSQIANLADYQHGFKEAIRYYGELRNLGLPVDHIDVGGGLGVDY
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCC
DGTHSRNASSINYDMDDYAGVVVGMLKEFCDAQALPHPHIFSESGRSLTAHHAMLVVQVT
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEEEEEEE
DVEKHNDDVPQIENKEALPETVQWLVDLLGPTDIEMVTETYWRATHYMSDVAAQYADGKL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCE
TLAEKALAEQCYFAVCRRLHNSLKARQRSHRQVLDELNDKLADKYICNFSVFQSLPDTWA
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCC
IDQVLPIIPLHRLDEEPLRRAVLQDLTCDSDGKINQYVDEQSIETSLPVHALNEGEDYLL
HHHHHHHCCHHCCCHHHHHHHHHHHCCCCCCCCHHHHHCHHHHHCCCCCEECCCCCHHHH
GVFLVGAYQEILGDMHNLFGDTDSVNIYQNADGSVYHAGIETHDTIEDMLRYVHLSPEEL
HHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEECCCCCHHHHHHHHHHHCCCHHHH
MTHYRDKCASARISASERTQFLDALRLGLTRSSYLSS
HHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12534463 [H]