Click here to switch to the map view.

The map label for this gene is cobH [H]

Identifier: 77456833

GI number: 77456833

Start: 697971

End: 698597

Strand: Direct

Name: cobH [H]

Synonym: Pfl01_0605

Alternate gene names: 77456833

Gene position: 697971-698597 (Clockwise)

Preceding gene: 77456832

Following gene: 77456834

Centisome position: 10.84

GC content: 66.83

Gene sequence:

>627_bases
ATGCTTGATTACATCCGCGACGGTCAGGAGATCTATCGCAACTCCTTCGCGATCATTCGCAGCGAGGCCAACCTGGCTCG
TATCCCGGCCGACCTGGAAAAACTCGCGGTGCGGGTGATTCACGCCTGCGGCATGGTCGAGGCCATCGACGGGCTGCAGT
TCTCCGAAGGCGCCGGCAAGGCCGGGCGCGATGCGCTGGCCGCTGGCGCGCCGATCCTCTGTGATGCGCGGATGGTTTCC
GAAGGTGTGACCCGCGCGCGCCTGCCGGCCAACAACCAAGTGATCTGCACCTTGCGCGACGACAGTGTGCCGGAACTGGC
GCGCGAGCTGGGCAACACTCGCTCGGCAGCTGCGCTGGAACTGTGGCGTCCGCATCTGGAAGGCAGCGTGGTGGTGATCG
GCAACGCGCCGACGGCGCTGTTCTATCTGCTGGAAATGCTCGACGCCGGCGCCCCGAAACCGGCGCTGATCCTCGGCTTC
CCGGTGGGCTTTGTCGGCGCTGCCGAATCCAAGGCCGAGCTGGCCGCCAACAGCCGTGGCGTGCCGTTCGTGATCATGCA
GGGCCGCCTCGGCGGCAGCGCCATGGCCGCCGCTGCGGTCAATGCCCTCGCCACGGAGATCGAATGA

Upstream 100 bases:

>100_bases
CGCGATGCAGCGCTGCCGGGTTTCGGCGCGCTGCACGCTCACAACCTTACTATCGAAGCGGCCGCGACCCTGCTCGCCGC
CCGCTCACGGAGCCCCCTTG

Downstream 100 bases:

>100_bases
TGCAGGCTCAAGGACGTTTGATTGGCCTGGGCGTCGGCCCCGGTGATCCGGAACTGATTACCGTCAAGGCCCTGCGCCTG
CTGCGCGAATCGCCGGTGGT

Product: precorrin-8X methylmutase

Products: NA

Alternate protein names: HBA synthase; Precorrin isomerase [H]

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MLDYIRDGQEIYRNSFAIIRSEANLARIPADLEKLAVRVIHACGMVEAIDGLQFSEGAGKAGRDALAAGAPILCDARMVS
EGVTRARLPANNQVICTLRDDSVPELARELGNTRSAAALELWRPHLEGSVVVIGNAPTALFYLLEMLDAGAPKPALILGF
PVGFVGAAESKAELAANSRGVPFVIMQGRLGGSAMAAAAVNALATEIE

Sequences:

>Translated_208_residues
MLDYIRDGQEIYRNSFAIIRSEANLARIPADLEKLAVRVIHACGMVEAIDGLQFSEGAGKAGRDALAAGAPILCDARMVS
EGVTRARLPANNQVICTLRDDSVPELARELGNTRSAAALELWRPHLEGSVVVIGNAPTALFYLLEMLDAGAPKPALILGF
PVGFVGAAESKAELAANSRGVPFVIMQGRLGGSAMAAAAVNALATEIE
>Mature_208_residues
MLDYIRDGQEIYRNSFAIIRSEANLARIPADLEKLAVRVIHACGMVEAIDGLQFSEGAGKAGRDALAAGAPILCDARMVS
EGVTRARLPANNQVICTLRDDSVPELARELGNTRSAAALELWRPHLEGSVVVIGNAPTALFYLLEMLDAGAPKPALILGF
PVGFVGAAESKAELAANSRGVPFVIMQGRLGGSAMAAAAVNALATEIE

Specific function: Catalyzes the conversion of precorrin-8X to hydrogenobyrinic acid; a methyl migration reaction during the transformation of precorrin-3 to form cobyrinic acid [H]

COG id: COG2082

COG function: function code H; Precorrin isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003722 [H]

Pfam domain/function: PF02570 CbiC [H]

EC number: =5.4.1.2 [H]

Molecular weight: Translated: 21823; Mature: 21823

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDYIRDGQEIYRNSFAIIRSEANLARIPADLEKLAVRVIHACGMVEAIDGLQFSEGAGK
CCCCHHCCHHHHHCCCEEEECCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCEECCCCCC
AGRDALAAGAPILCDARMVSEGVTRARLPANNQVICTLRDDSVPELARELGNTRSAAALE
CCCHHHHCCCCEEEHHHHHHHCCCEEECCCCCEEEEEECCCCHHHHHHHHCCCCCHHHHH
LWRPHLEGSVVVIGNAPTALFYLLEMLDAGAPKPALILGFPVGFVGAAESKAELAANSRG
HHHHCCCCCEEEEECCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHCCCCC
VPFVIMQGRLGGSAMAAAAVNALATEIE
CCEEEEECCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLDYIRDGQEIYRNSFAIIRSEANLARIPADLEKLAVRVIHACGMVEAIDGLQFSEGAGK
CCCCHHCCHHHHHCCCEEEECCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCEECCCCCC
AGRDALAAGAPILCDARMVSEGVTRARLPANNQVICTLRDDSVPELARELGNTRSAAALE
CCCHHHHCCCCEEEHHHHHHHCCCEEECCCCCEEEEEECCCCHHHHHHHHCCCCCHHHHH
LWRPHLEGSVVVIGNAPTALFYLLEMLDAGAPKPALILGFPVGFVGAAESKAELAANSRG
HHHHCCCCCEEEEECCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHCCCCC
VPFVIMQGRLGGSAMAAAAVNALATEIE
CCEEEEECCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]