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The map label for this gene is sugE [H]

Identifier: 77456798

GI number: 77456798

Start: 663453

End: 663758

Strand: Direct

Name: sugE [H]

Synonym: Pfl01_0570

Alternate gene names: 77456798

Gene position: 663453-663758 (Clockwise)

Preceding gene: 77456797

Following gene: 77456799

Centisome position: 10.3

GC content: 64.38

Gene sequence:

>306_bases
GTGGCCTGGCTGTTTCTGCTGATCGCCGCCGGGTTCGAGGTCACCTTCGCCATGGGCATGAAGTACGCCGAGGGTTTCAC
CCGGCTCTGGCCGTCGCTGATCACCGTGGTCGCGGCGGTGGGCGGGGTGTACTTCCTGACCCTGGCGATGCGCGAGTTGC
CGGTGAGCATCGCCTATCCGATTTGGACCGCCATCGGTTCATTGGGCACGGTGTTTCTCGGTTTCGCTCTGCTGGGCGAG
AGCCTGACGCTGGTGAAGTTGCTGTCGGTGGGGCTGATTGTGGCGGGGGTGGTGGGGCTGAAGTAG

Upstream 100 bases:

>100_bases
GGTGGTCGCCGCCGAGGGCGAGGAATCCGCCGAGCGCACCTTCGCGGTGTCGGTGGCCGAGGCCGAGCAGCGCTTGCTCG
ACCTGGCCCGGGCGTTCTAG

Downstream 100 bases:

>100_bases
GCTGGTCGTGGAGTTGTCATCATCGAGGCGGATGCTTGGCGGGCGTTTTGCACGCCCTGCATCCACTTACCGACCACAAG
GATGTTTGCCCATGTCGCAA

Product: small multidrug resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 101; Mature: 100

Protein sequence:

>101_residues
MAWLFLLIAAGFEVTFAMGMKYAEGFTRLWPSLITVVAAVGGVYFLTLAMRELPVSIAYPIWTAIGSLGTVFLGFALLGE
SLTLVKLLSVGLIVAGVVGLK

Sequences:

>Translated_101_residues
MAWLFLLIAAGFEVTFAMGMKYAEGFTRLWPSLITVVAAVGGVYFLTLAMRELPVSIAYPIWTAIGSLGTVFLGFALLGE
SLTLVKLLSVGLIVAGVVGLK
>Mature_100_residues
AWLFLLIAAGFEVTFAMGMKYAEGFTRLWPSLITVVAAVGGVYFLTLAMRELPVSIAYPIWTAIGSLGTVFLGFALLGES
LTLVKLLSVGLIVAGVVGLK

Specific function: Quaternary ammonium compound efflux pump. Confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. SugE (TC 2.A.7.1.4) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082378, Length=101, Percent_Identity=48.5148514851485, Blast_Score=94, Evalue=2e-21,
Organism=Escherichia coli, GI1786755, Length=79, Percent_Identity=36.7088607594937, Blast_Score=59, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 10712; Mature: 10581

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWLFLLIAAGFEVTFAMGMKYAEGFTRLWPSLITVVAAVGGVYFLTLAMRELPVSIAYP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
IWTAIGSLGTVFLGFALLGESLTLVKLLSVGLIVAGVVGLK
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AWLFLLIAAGFEVTFAMGMKYAEGFTRLWPSLITVVAAVGGVYFLTLAMRELPVSIAYP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
IWTAIGSLGTVFLGFALLGESLTLVKLLSVGLIVAGVVGLK
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]