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The map label for this gene is yccK [H]

Identifier: 77456714

GI number: 77456714

Start: 563459

End: 564271

Strand: Reverse

Name: yccK [H]

Synonym: Pfl01_0486

Alternate gene names: 77456714

Gene position: 564271-563459 (Counterclockwise)

Preceding gene: 77456715

Following gene: 77456713

Centisome position: 8.76

GC content: 62.73

Gene sequence:

>813_bases
ATGAGCCTGCCGACCCTGCACGATCTGCATCGCCCACTGGGCAGCACCGGCCTGCTGGTTTCGCCGCTGGGCCTGGGCAC
CGTCAAACTCGGCCGCGACCAGGGCGTGAAATACCCCAACGGCTTCCAGATCCCCGACGATGACGCTGCGCGCATGTTGC
TCAAACAGGCGCGGGAGCTGGGCATCAACCTGATCGACACCGCCCCGGCCTATGGCCGCAGCGAAGAACGCCTCGGCCCA
CTGCTGCGTGGCCAGCGTCAGGACTGGGTGATCGTCAGCAAGGTCGGCGAAGAATTCGTCGACGGCCAGTCGACCCACGA
TTTCAGCGCCGCTCACACCCGGATGTCGGTGGAGCGCAGTCTGCAACGTCTTGAAACCGATTTTATCGACCTGGTGCTGG
TGCACTCCGATGGCAACGATCTGGCGATCCTCAACGACAGCGAAGTCTACGCAACCCTCGCGGCGCTGAAGGCCGAGGGC
AAGATTCGCGGCTTCGGTTTTTCCGGCAAAACCGTCGACGGTGGCCTCAAAGCACTGGAGCAAGGCGACTGCGCGATGGT
CACCTACAATCTGAACGAACAAAACGAGAAGGCGGTCATTGACTATGCTGCTGCCCACGGCAAAGCCATTCTGGTGAAGA
AGGCGCTGGCCAGTGGTCATGTGTGCCTGAGTCCCGGTGTGGATCCGGTGCGCGCCAGCTTCGAGTTGCTGTTCGCCCAG
CCCGGCGTGGCCAGTGCCATCGTCGGGACGATCAATCCGCTGCACCTCGCCCACAACGTTGCGACCGTTGCCCAGGTCCT
TCGTGGTCACTGA

Upstream 100 bases:

>100_bases
CCTCCCTGGAACGCGACGGTATCCAGCCGAGCCATCCTGGTCCGCTGCCCGAGCTGCCAAAACCACCGATGGGCGTTCCC
GCCTGGGAGCAATTGCTGCC

Downstream 100 bases:

>100_bases
CGCCGCCTCGCGGCCTTAAGCAGGAGCCGACATGCCGCGTACGCTCATCAGAAAGAACCCGAGCAACTTCAAGACGCTGC
CGCTGTTCGTCGAAGCCACG

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MSLPTLHDLHRPLGSTGLLVSPLGLGTVKLGRDQGVKYPNGFQIPDDDAARMLLKQARELGINLIDTAPAYGRSEERLGP
LLRGQRQDWVIVSKVGEEFVDGQSTHDFSAAHTRMSVERSLQRLETDFIDLVLVHSDGNDLAILNDSEVYATLAALKAEG
KIRGFGFSGKTVDGGLKALEQGDCAMVTYNLNEQNEKAVIDYAAAHGKAILVKKALASGHVCLSPGVDPVRASFELLFAQ
PGVASAIVGTINPLHLAHNVATVAQVLRGH

Sequences:

>Translated_270_residues
MSLPTLHDLHRPLGSTGLLVSPLGLGTVKLGRDQGVKYPNGFQIPDDDAARMLLKQARELGINLIDTAPAYGRSEERLGP
LLRGQRQDWVIVSKVGEEFVDGQSTHDFSAAHTRMSVERSLQRLETDFIDLVLVHSDGNDLAILNDSEVYATLAALKAEG
KIRGFGFSGKTVDGGLKALEQGDCAMVTYNLNEQNEKAVIDYAAAHGKAILVKKALASGHVCLSPGVDPVRASFELLFAQ
PGVASAIVGTINPLHLAHNVATVAQVLRGH
>Mature_269_residues
SLPTLHDLHRPLGSTGLLVSPLGLGTVKLGRDQGVKYPNGFQIPDDDAARMLLKQARELGINLIDTAPAYGRSEERLGPL
LRGQRQDWVIVSKVGEEFVDGQSTHDFSAAHTRMSVERSLQRLETDFIDLVLVHSDGNDLAILNDSEVYATLAALKAEGK
IRGFGFSGKTVDGGLKALEQGDCAMVTYNLNEQNEKAVIDYAAAHGKAILVKKALASGHVCLSPGVDPVRASFELLFAQP
GVASAIVGTINPLHLAHNVATVAQVLRGH

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Escherichia coli, GI87081735, Length=236, Percent_Identity=30.5084745762712, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1788070, Length=189, Percent_Identity=32.2751322751323, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI212645785, Length=227, Percent_Identity=29.0748898678414, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323684, Length=159, Percent_Identity=36.4779874213836, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24646155, Length=165, Percent_Identity=38.1818181818182, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24646159, Length=177, Percent_Identity=34.4632768361582, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 28902; Mature: 28771

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLPTLHDLHRPLGSTGLLVSPLGLGTVKLGRDQGVKYPNGFQIPDDDAARMLLKQAREL
CCCCCHHHHHCCCCCCCCEEECCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
GINLIDTAPAYGRSEERLGPLLRGQRQDWVIVSKVGEEFVDGQSTHDFSAAHTRMSVERS
CCEEEECCCCCCCCHHHHHHHHCCCCCCEEEEEHHHHHHHCCCCCCCHHHHHHHHHHHHH
LQRLETDFIDLVLVHSDGNDLAILNDSEVYATLAALKAEGKIRGFGFSGKTVDGGLKALE
HHHHHHCEEEEEEEECCCCEEEEEECCHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHC
QGDCAMVTYNLNEQNEKAVIDYAAAHGKAILVKKALASGHVCLSPGVDPVRASFELLFAQ
CCCEEEEEEECCCCCCEEEEEEHHCCCCEEEEEHHHHCCCEEECCCCCHHHHCEEEEEEC
PGVASAIVGTINPLHLAHNVATVAQVLRGH
CCHHHHHHHCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLPTLHDLHRPLGSTGLLVSPLGLGTVKLGRDQGVKYPNGFQIPDDDAARMLLKQAREL
CCCCHHHHHCCCCCCCCEEECCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
GINLIDTAPAYGRSEERLGPLLRGQRQDWVIVSKVGEEFVDGQSTHDFSAAHTRMSVERS
CCEEEECCCCCCCCHHHHHHHHCCCCCCEEEEEHHHHHHHCCCCCCCHHHHHHHHHHHHH
LQRLETDFIDLVLVHSDGNDLAILNDSEVYATLAALKAEGKIRGFGFSGKTVDGGLKALE
HHHHHHCEEEEEEEECCCCEEEEEECCHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHC
QGDCAMVTYNLNEQNEKAVIDYAAAHGKAILVKKALASGHVCLSPGVDPVRASFELLFAQ
CCCEEEEEEECCCCCCEEEEEEHHCCCCEEEEEHHHHCCCEEECCCCCHHHHCEEEEEEC
PGVASAIVGTINPLHLAHNVATVAQVLRGH
CCHHHHHHHCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]