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The map label for this gene is grx [H]

Identifier: 77456563

GI number: 77456563

Start: 380599

End: 380853

Strand: Direct

Name: grx [H]

Synonym: Pfl01_0335

Alternate gene names: 77456563

Gene position: 380599-380853 (Clockwise)

Preceding gene: 77456562

Following gene: 77456564

Centisome position: 5.91

GC content: 62.75

Gene sequence:

>255_bases
ATGAGCGACGTCATCGTCTACTCCAGCGATTACTGCCCTTACTGCTCGCGCGCCAAGTACCTGCTCGCGAACAAAGGCGT
GGCCTTCGAAGAGATCAAGGTCGATGGCAAGCCGCAGGTGCGCGCCGCCATGGCCCAGAAGGCCGGACGCACGTCCGTGC
CGCAGATCTGGATCGGCGACACCCATGTCGGCGGATGTGATGATTTGTATGCCCTGGAGCGTGCCGGCAAGCTCGACGCG
CTGCTCAAGGCCTGA

Upstream 100 bases:

>100_bases
ACCCACGCCCGCGAGCTGATGAAGGCCGGCTTCACCGCCGCCAAGCTGTCCGGCGGGATTTCCAGCTGGAAAGGCGACAA
CCTGCCGTTGGTGAAGTGAC

Downstream 100 bases:

>100_bases
ACTGCTGCACCTGCAAACCAAGAACCCTAAAAGACCCAAGATCAGAAAGGATCTGAGATGACTGACCAACAGAACACTGC
AGCCAGCGAAGAAGAAACCG

Product: glutaredoxin GrxC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 84; Mature: 83

Protein sequence:

>84_residues
MSDVIVYSSDYCPYCSRAKYLLANKGVAFEEIKVDGKPQVRAAMAQKAGRTSVPQIWIGDTHVGGCDDLYALERAGKLDA
LLKA

Sequences:

>Translated_84_residues
MSDVIVYSSDYCPYCSRAKYLLANKGVAFEEIKVDGKPQVRAAMAQKAGRTSVPQIWIGDTHVGGCDDLYALERAGKLDA
LLKA
>Mature_83_residues
SDVIVYSSDYCPYCSRAKYLLANKGVAFEEIKVDGKPQVRAAMAQKAGRTSVPQIWIGDTHVGGCDDLYALERAGKLDAL
LKA

Specific function: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins [H]

COG id: COG0695

COG function: function code O; Glutaredoxin and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790039, Length=83, Percent_Identity=54.2168674698795, Blast_Score=103, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR014025
- InterPro:   IPR011900
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 9139; Mature: 9007

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: PS00195 GLUTAREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDVIVYSSDYCPYCSRAKYLLANKGVAFEEIKVDGKPQVRAAMAQKAGRTSVPQIWIGD
CCCEEEECCCCCCCCCCCEEEECCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCEEEECC
THVGGCDDLYALERAGKLDALLKA
CCCCCCCHHHHHHHCCCCHHHHCC
>Mature Secondary Structure 
SDVIVYSSDYCPYCSRAKYLLANKGVAFEEIKVDGKPQVRAAMAQKAGRTSVPQIWIGD
CCEEEECCCCCCCCCCCEEEECCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCEEEECC
THVGGCDDLYALERAGKLDALLKA
CCCCCCCHHHHHHHCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]