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The map label for this gene is mdtA [H]

Identifier: 77456459

GI number: 77456459

Start: 271295

End: 272359

Strand: Direct

Name: mdtA [H]

Synonym: Pfl01_0231

Alternate gene names: 77456459

Gene position: 271295-272359 (Clockwise)

Preceding gene: 77456458

Following gene: 77456460

Centisome position: 4.21

GC content: 63.1

Gene sequence:

>1065_bases
ATGAAGCGTCTGGGGCTGTTATCCATTGGCGTGTTGCTGGCCGCCTGCTCGAAAAGCGAGCCACCGCCGGAGCCGGTACG
GCCGGTGTTGTCGGTCAAGGTCGAAGCGTTGAGCGAGGAAAACCTCGGGCGTTTCGCCGGCAGCATTCAGGCGCGCTATG
AAAGCAATACCGGTTTTCGTGTCGGCGGGCGCATTGCCAGCCGCAACGTCGACGTCGGTACCGAGGTGCAGAAGGGCACG
CTGCTCGCTACGCTCGATCCGACCGATCAGCAGAACCAGTTGCGTTCGGCCCAGGGCGATCTGGCGAGGGTTCAGGCACA
ACTGATCAACGCCCAGGCCAACGCCCGCCGTCAGCAAGCGCTGTTCGACCGGGGCGTGGGTGCGCAGGCGCAACTGGACA
TTGCCATGACGGACCTGAAAACCACCCAGGCCTCGCTGGATCAGGCACGCGCGGCGGTCAATCAAAGCAAGGATCAACTC
GATTACACCCAGCTGCGCTCCGATCACAAAGCCGTGGTCACCGCGTGGAACGCCGAGGCCGGGCAAGTGGTGACGGCGGG
CCAGCAAGTGGTGACTTTGGCGCAACCGGACATCAAGGAAGCGGTGATCGATCTGCCGGACACCCTGGTCGATGAGATCC
CGTCCGACGTGGTGTTTCTGGTGGCCGGCCAGCTCGACCCGAACATCAACACCACGGCCACCCTGCGCGAGATCGAACCG
CAGGCACAAAGTGCCACGCGCACCCGCCGTGCACGGTTGACCCTGGCCAATACGCCCGACGGCTTTCGCCTCGGCACGGC
GATCAGCGTCACCCTCAGCTCGGCGATCAAACCACGTATCGAATTGCCAGCTACGGCGTTGCAGGAGGCCGATGGCAAAC
AGCGGATCTGGGTCATCGACACCCAAAGCAAAACCGTCAACCCGCGCGACGTCAGCGTGATCAGCCGCACCGACAGCAGC
GTTGTACTTGCGGGTGGCGTGAAGAACGGCGAGCGCGTGGTCAGCGCCGGCGTCAACAGTCTCAAACCCGGACAATCCGT
GAAACTTGACGAGGACAGTCAATGA

Upstream 100 bases:

>100_bases
GGGAAAAAGTCATCGTCGCGGGTGGGCAGTTGCTGCATCCGGGCATGAAGGTCGAAATTGCCGAAAACACCTACAAGGAT
CTGCAGCCGGGAGCACAGCC

Downstream 100 bases:

>100_bases
AAGGGTCTTTCAATCTCTCCGAATGGGCCCTCAAGCATCAGTCTTTCGTCTGGTATCTGATGTTCGTCGCGTTGCTCATG
GGGGTGTTCTCCTACTTCAA

Product: secretion protein HlyD

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MKRLGLLSIGVLLAACSKSEPPPEPVRPVLSVKVEALSEENLGRFAGSIQARYESNTGFRVGGRIASRNVDVGTEVQKGT
LLATLDPTDQQNQLRSAQGDLARVQAQLINAQANARRQQALFDRGVGAQAQLDIAMTDLKTTQASLDQARAAVNQSKDQL
DYTQLRSDHKAVVTAWNAEAGQVVTAGQQVVTLAQPDIKEAVIDLPDTLVDEIPSDVVFLVAGQLDPNINTTATLREIEP
QAQSATRTRRARLTLANTPDGFRLGTAISVTLSSAIKPRIELPATALQEADGKQRIWVIDTQSKTVNPRDVSVISRTDSS
VVLAGGVKNGERVVSAGVNSLKPGQSVKLDEDSQ

Sequences:

>Translated_354_residues
MKRLGLLSIGVLLAACSKSEPPPEPVRPVLSVKVEALSEENLGRFAGSIQARYESNTGFRVGGRIASRNVDVGTEVQKGT
LLATLDPTDQQNQLRSAQGDLARVQAQLINAQANARRQQALFDRGVGAQAQLDIAMTDLKTTQASLDQARAAVNQSKDQL
DYTQLRSDHKAVVTAWNAEAGQVVTAGQQVVTLAQPDIKEAVIDLPDTLVDEIPSDVVFLVAGQLDPNINTTATLREIEP
QAQSATRTRRARLTLANTPDGFRLGTAISVTLSSAIKPRIELPATALQEADGKQRIWVIDTQSKTVNPRDVSVISRTDSS
VVLAGGVKNGERVVSAGVNSLKPGQSVKLDEDSQ
>Mature_354_residues
MKRLGLLSIGVLLAACSKSEPPPEPVRPVLSVKVEALSEENLGRFAGSIQARYESNTGFRVGGRIASRNVDVGTEVQKGT
LLATLDPTDQQNQLRSAQGDLARVQAQLINAQANARRQQALFDRGVGAQAQLDIAMTDLKTTQASLDQARAAVNQSKDQL
DYTQLRSDHKAVVTAWNAEAGQVVTAGQQVVTLAQPDIKEAVIDLPDTLVDEIPSDVVFLVAGQLDPNINTTATLREIEP
QAQSATRTRRARLTLANTPDGFRLGTAISVTLSSAIKPRIELPATALQEADGKQRIWVIDTQSKTVNPRDVSVISRTDSS
VVLAGGVKNGERVVSAGVNSLKPGQSVKLDEDSQ

Specific function: Unknown

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87081796, Length=362, Percent_Identity=25.9668508287293, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1789929, Length=370, Percent_Identity=25.9459459459459, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI87082036, Length=343, Percent_Identity=23.3236151603499, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 37838; Mature: 37838

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLGLLSIGVLLAACSKSEPPPEPVRPVLSVKVEALSEENLGRFAGSIQARYESNTGFR
CCCCHHHHHHHHHHHHCCCCCCCHHCCHHHHHHHHHHCCCHHHHHHHHEEEEEECCCCEE
VGGRIASRNVDVGTEVQKGTLLATLDPTDQQNQLRSAQGDLARVQAQLINAQANARRQQA
ECCEEECCCCCCCCCCCCCEEEEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LFDRGVGAQAQLDIAMTDLKTTQASLDQARAAVNQSKDQLDYTQLRSDHKAVVTAWNAEA
HHHCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEECCCC
GQVVTAGQQVVTLAQPDIKEAVIDLPDTLVDEIPSDVVFLVAGQLDPNINTTATLREIEP
CCEEECCCEEEEECCCCHHHHHHCCCHHHHHHCCCCEEEEEECCCCCCCCCEEEEECCCC
QAQSATRTRRARLTLANTPDGFRLGTAISVTLSSAIKPRIELPATALQEADGKQRIWVID
HHHHHHHHHHEEEEECCCCCCEEECCEEEEEEHHHCCCCCCCCHHHHHCCCCCCEEEEEE
TQSKTVNPRDVSVISRTDSSVVLAGGVKNGERVVSAGVNSLKPGQSVKLDEDSQ
CCCCCCCCCCEEEEEECCCCEEEECCCCCCHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKRLGLLSIGVLLAACSKSEPPPEPVRPVLSVKVEALSEENLGRFAGSIQARYESNTGFR
CCCCHHHHHHHHHHHHCCCCCCCHHCCHHHHHHHHHHCCCHHHHHHHHEEEEEECCCCEE
VGGRIASRNVDVGTEVQKGTLLATLDPTDQQNQLRSAQGDLARVQAQLINAQANARRQQA
ECCEEECCCCCCCCCCCCCEEEEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LFDRGVGAQAQLDIAMTDLKTTQASLDQARAAVNQSKDQLDYTQLRSDHKAVVTAWNAEA
HHHCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEECCCC
GQVVTAGQQVVTLAQPDIKEAVIDLPDTLVDEIPSDVVFLVAGQLDPNINTTATLREIEP
CCEEECCCEEEEECCCCHHHHHHCCCHHHHHHCCCCEEEEEECCCCCCCCCEEEEECCCC
QAQSATRTRRARLTLANTPDGFRLGTAISVTLSSAIKPRIELPATALQEADGKQRIWVID
HHHHHHHHHHEEEEECCCCCCEEECCEEEEEEHHHCCCCCCCCHHHHHCCCCCCEEEEEE
TQSKTVNPRDVSVISRTDSSVVLAGGVKNGERVVSAGVNSLKPGQSVKLDEDSQ
CCCCCCCCCCEEEEEECCCCEEEECCCCCCHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]