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The map label for this gene is hipA [C]

Identifier: 77456433

GI number: 77456433

Start: 243291

End: 244436

Strand: Direct

Name: hipA [C]

Synonym: Pfl01_0205

Alternate gene names: 77456433

Gene position: 243291-244436 (Clockwise)

Preceding gene: 77456432

Following gene: 77456435

Centisome position: 3.78

GC content: 57.42

Gene sequence:

>1146_bases
ATGGACAGTGTGTTCAGTTATCGCGAGGACGCCATCGACGAGAATGCAGTGTCGCTGACAATGCCGACCCGGCTGGAGAG
CTACGGCTGGGAGCGGGGCATTCATCCCGTCTTCGAAATGAATCTGCCGGAAGGCGCGCTGCGCGATGAACTGGTTCGAC
GCTTCAGTAAAGCAGTGCGCGGTTTTGATGATTTCGCCTTGCTCGCTATCGTCGGACCGCATCAGTTGGGACGGCTGGCG
ATTACCAGCGAGTCGGCAACCGAGCGTCAGCCCGAAACATCATTGGCCGAGCTTTTGGTGCATGACGGTGCCCAGGGATT
GTTCGATGATTTGCTACAGAAGTACGGCCAATACTCCGGGGTTTCGGGCGTGCAGCCCAAAGTTCTGGTGCGCGACAGTG
CGGCAGCAGTTGATCGCCTGACTCACCGAGGCTCCACACATCTGGTCAAAGCCTTCCGTCCCGAAGAGTTTCCCGAGCTG
GCGACCAACGAGTACTTCTGTATGCGCGCCGCAGCGCTTAGCGGACTTGAAGTGCCAAAGTTTGAATTGAGTGAGCAGGG
CAAGTTTTTGGTGGTCGAGCGTTTTGACCTGATTGAGCACGGCTATCTGGGTTTCGAGGACTTTTGCGTACTCAACGGCT
GGTCTTCCAGAGCCAAATACGATGGTTCTTACGAAGGCGCTGCCCGACAGATCAAGGCCTTTGTTTCGCCTGCGCTGTTG
AGTCAGGCGCTGGAGGCTTTTTTCAAGATCGTGGCGCTGTCAGCGGGACTGAAAAACGGCGATGCGCACCTGAAGAACTT
CGGTGTGCTGTATGACCATTGCGGTGCGCAGGCTTCGATCCGGCTGGCCCCGGCTTACGACATCATCACCACATCGGTTT
ACATCAGGAACGACAGCCTGGCCTTGCTGCTGGGCGGGTCGAAGGCATGGCCCAAGCAGAAGGCGCTCATCCGCTTCGGC
CGTACGGCGTGCAATCTCACTGAAGGCCGGTGCAATGAACTACTGCAGCAGGTTGTTCATGGCATGCAGACGGCGATGGC
GGAAATGCTCGAGCATTGCCGAACCCATCAGTCATTCGCCGAGGTGGGTACGGCAATGATCGAGCAGTGGGAGTCCGGGA
TTGAACGCAGTCTGACCAAGGGTTGA

Upstream 100 bases:

>100_bases
GCGTTGCAGAAGGCCAATTTCCATGACTGAGCCGACAGATCGCTTGCACATCACCGTCGCTGATAGCCCGGTCGGAACGC
TCGGTCGAGGGCAGCCGGGC

Downstream 100 bases:

>100_bases
GCGACCCATTTGCGCTCAGCGCAACTGATCCCGAAACTGCCCCGGCGTCATCCCGGTCCAGCGTTTGAACGCGCGGCTGA
AGCTGCTGGTGTCGGCAAAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MDSVFSYREDAIDENAVSLTMPTRLESYGWERGIHPVFEMNLPEGALRDELVRRFSKAVRGFDDFALLAIVGPHQLGRLA
ITSESATERQPETSLAELLVHDGAQGLFDDLLQKYGQYSGVSGVQPKVLVRDSAAAVDRLTHRGSTHLVKAFRPEEFPEL
ATNEYFCMRAAALSGLEVPKFELSEQGKFLVVERFDLIEHGYLGFEDFCVLNGWSSRAKYDGSYEGAARQIKAFVSPALL
SQALEAFFKIVALSAGLKNGDAHLKNFGVLYDHCGAQASIRLAPAYDIITTSVYIRNDSLALLLGGSKAWPKQKALIRFG
RTACNLTEGRCNELLQQVVHGMQTAMAEMLEHCRTHQSFAEVGTAMIEQWESGIERSLTKG

Sequences:

>Translated_381_residues
MDSVFSYREDAIDENAVSLTMPTRLESYGWERGIHPVFEMNLPEGALRDELVRRFSKAVRGFDDFALLAIVGPHQLGRLA
ITSESATERQPETSLAELLVHDGAQGLFDDLLQKYGQYSGVSGVQPKVLVRDSAAAVDRLTHRGSTHLVKAFRPEEFPEL
ATNEYFCMRAAALSGLEVPKFELSEQGKFLVVERFDLIEHGYLGFEDFCVLNGWSSRAKYDGSYEGAARQIKAFVSPALL
SQALEAFFKIVALSAGLKNGDAHLKNFGVLYDHCGAQASIRLAPAYDIITTSVYIRNDSLALLLGGSKAWPKQKALIRFG
RTACNLTEGRCNELLQQVVHGMQTAMAEMLEHCRTHQSFAEVGTAMIEQWESGIERSLTKG
>Mature_381_residues
MDSVFSYREDAIDENAVSLTMPTRLESYGWERGIHPVFEMNLPEGALRDELVRRFSKAVRGFDDFALLAIVGPHQLGRLA
ITSESATERQPETSLAELLVHDGAQGLFDDLLQKYGQYSGVSGVQPKVLVRDSAAAVDRLTHRGSTHLVKAFRPEEFPEL
ATNEYFCMRAAALSGLEVPKFELSEQGKFLVVERFDLIEHGYLGFEDFCVLNGWSSRAKYDGSYEGAARQIKAFVSPALL
SQALEAFFKIVALSAGLKNGDAHLKNFGVLYDHCGAQASIRLAPAYDIITTSVYIRNDSLALLLGGSKAWPKQKALIRFG
RTACNLTEGRCNELLQQVVHGMQTAMAEMLEHCRTHQSFAEVGTAMIEQWESGIERSLTKG

Specific function: Unbalanced Or Excessive Expression Of Hipa Is Toxic To The Cell. [C]

COG id: COG3550

COG function: function code R; Uncharacterized protein related to capsule biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli hipA, H.influenzae HI_0665 and y4dM [H]

Homologues:

Organism=Escherichia coli, GI1787785, Length=310, Percent_Identity=28.7096774193548, Blast_Score=68, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012893
- InterPro:   IPR012894
- InterPro:   IPR017508 [H]

Pfam domain/function: PF07804 HipA_C; PF07805 HipA_N [H]

EC number: NA

Molecular weight: Translated: 42189; Mature: 42189

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSVFSYREDAIDENAVSLTMPTRLESYGWERGIHPVFEMNLPEGALRDELVRRFSKAVR
CCCHHHHHHHCCCCCCEEEECCHHHHHCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHC
GFDDFALLAIVGPHQLGRLAITSESATERQPETSLAELLVHDGAQGLFDDLLQKYGQYSG
CCCCEEEEEEECCHHHCCEEEECCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCC
VSGVQPKVLVRDSAAAVDRLTHRGSTHLVKAFRPEEFPELATNEYFCMRAAALSGLEVPK
CCCCCCEEEEECHHHHHHHHHHCCCHHHHHHCCCCCCHHHHCCCHHHHHHHHHCCCCCCC
FELSEQGKFLVVERFDLIEHGYLGFEDFCVLNGWSSRAKYDGSYEGAARQIKAFVSPALL
CCCCCCCCEEEEEEHHHHHCCCCCHHHEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHH
SQALEAFFKIVALSAGLKNGDAHLKNFGVLYDHCGAQASIRLAPAYDIITTSVYIRNDSL
HHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHCCCCCCEEEECCCHHEEEEEEEEECCCE
ALLLGGSKAWPKQKALIRFGRTACNLTEGRCNELLQQVVHGMQTAMAEMLEHCRTHQSFA
EEEECCCCCCCHHHHHHHHCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVGTAMIEQWESGIERSLTKG
HHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDSVFSYREDAIDENAVSLTMPTRLESYGWERGIHPVFEMNLPEGALRDELVRRFSKAVR
CCCHHHHHHHCCCCCCEEEECCHHHHHCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHC
GFDDFALLAIVGPHQLGRLAITSESATERQPETSLAELLVHDGAQGLFDDLLQKYGQYSG
CCCCEEEEEEECCHHHCCEEEECCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCC
VSGVQPKVLVRDSAAAVDRLTHRGSTHLVKAFRPEEFPELATNEYFCMRAAALSGLEVPK
CCCCCCEEEEECHHHHHHHHHHCCCHHHHHHCCCCCCHHHHCCCHHHHHHHHHCCCCCCC
FELSEQGKFLVVERFDLIEHGYLGFEDFCVLNGWSSRAKYDGSYEGAARQIKAFVSPALL
CCCCCCCCEEEEEEHHHHHCCCCCHHHEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHH
SQALEAFFKIVALSAGLKNGDAHLKNFGVLYDHCGAQASIRLAPAYDIITTSVYIRNDSL
HHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHCCCCCCEEEECCCHHEEEEEEEEECCCE
ALLLGGSKAWPKQKALIRFGRTACNLTEGRCNELLQQVVHGMQTAMAEMLEHCRTHQSFA
EEEECCCCCCCHHHHHHHHCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVGTAMIEQWESGIERSLTKG
HHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]