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The map label for this gene is aprE [H]

Identifier: 77456364

GI number: 77456364

Start: 164533

End: 165900

Strand: Direct

Name: aprE [H]

Synonym: Pfl01_0136

Alternate gene names: 77456364

Gene position: 164533-165900 (Clockwise)

Preceding gene: 77456363

Following gene: 77456365

Centisome position: 2.56

GC content: 61.99

Gene sequence:

>1368_bases
GTGTTGCTTAAGTCGGGTTTCAAGGATTCGATCCGCCGCTACTTCAAAGGCTCGGCATCGCTGCAGGGCCAGCCGCTGCC
GGAGGTCAACAAGGCCTTGATCGAGGACGCGCCACGCGTGGTGCGCCTGACGATCTGGGCGATCATCGGCTTCTTCGTGT
TCCTGATGCTGTGGGCCAACTTCGCCGTCATCGACGAAGTGACCAAGGGCGACGGCAAGGCGATTCCTTCGTCGAAGATC
CAGAAAATCCAGAACCTCGAGGGCGGTATCGTCTCCGAACTGTTCGTCAAGGAAGGCCAGATCGTCGAGGCCGGCGCGCC
GCTGGTTCGCCTGGACGACACGCGTTTTGCGTCCAATGTCGGCGAGACCGAAGCGGATCGCCTGTCGATGCTGCTGCGGG
TCGAGCGCCTGAGCGCCGAGGTCGATGACCGCCCGCTGAATTTCCCCGAGGACGTGCTCAAAGCCGTGCCGGGTCAGGCC
AAGAGCGAAGAGTCGTTGTACATCAGCCGTCGCCAGCAACTGCACGATGAAGTTGGGGGGTTGCAGGAGCAGTTGATCCA
GCGTCAGCAAGAGCTGCGCGAATTCACCTCGAAACAGGCGCAGTACCGCCAGCAACTCGGCCTGCAACGCCAGGAAATCA
ACATGTCCGAGCCGTTGGTGGCCCAGGGCGCGGTGTCGCCGGTGGAAGTGCTGCGACTCAAGCGTGCGGAAGTGGAAACC
CGTGGTCAGCTCGACGCCACCACTTTGGCGATCCCGCGCGCCGAATCGGCGATCAAGGAAGTGCAGCGCAAGATCGACGA
GACCCGCGGCAAATTCCGCAGCGAAGCCCTGACTCAGCTCAACGAGGCGCGCACCGACCTGAACAAGGCCCAGGCCACCG
GCAAGGCGCTGGAAGACCGGGTCAGTCGGACGCTCGTTACTTCGCCGGTGCGGGGCATCGTCAACAAGATGCTGGTCAAC
ACCATCGGCGGCGTGATCCAGCCGGGCAGCGACCTGTTGGAAATCGTGCCGCTGGACGACACCCTGCTGGTCGAAGCGAA
GATTCGCCCGCAGGACATCGCGTTCCTGCATCCTGGCCAGGAAGCCACGGTGAAATTCACCGCGTATGACTACACCATCT
ACGGCGGTCTCAAAGCCAAGCTGGAACAGATCGGCGCCGACACCATCACCGACGAAGACAAGAAAACCACCTACTACGTC
ATCAAGCTGCGCACCGAGCGCAGCCATCTCGGCACCGACGAGAAGCCGTTGCTGATCATCCCGGGGATGGTGGCGTCGGT
GGACATCATCACCGGCAAGAAGACCGTGTTGAGCTATCTGCTCAAGCCAATCATCCGGGCGCGCGCCGAGGCGTTGCACG
AACGGTAA

Upstream 100 bases:

>100_bases
CTGTCGCTGGTCGACCGCCTGCTGGTGGTCGACCGTGGACAGATCCTCGCCGACGGCCCGAAAGCGGCCGTCATGGAAGC
GTTGAAGAAGGGGCAGATCA

Downstream 100 bases:

>100_bases
ATCTTCACGGACGCCTTCGAGGGACTCGCGGAGGCGTTCGTCGCACCAACACATTCCGTCCAGAAGTGACACAAATGGTC
ACTCACCATCCAGTCCATTC

Product: Type I secretion membrane fusion protein, HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MLLKSGFKDSIRRYFKGSASLQGQPLPEVNKALIEDAPRVVRLTIWAIIGFFVFLMLWANFAVIDEVTKGDGKAIPSSKI
QKIQNLEGGIVSELFVKEGQIVEAGAPLVRLDDTRFASNVGETEADRLSMLLRVERLSAEVDDRPLNFPEDVLKAVPGQA
KSEESLYISRRQQLHDEVGGLQEQLIQRQQELREFTSKQAQYRQQLGLQRQEINMSEPLVAQGAVSPVEVLRLKRAEVET
RGQLDATTLAIPRAESAIKEVQRKIDETRGKFRSEALTQLNEARTDLNKAQATGKALEDRVSRTLVTSPVRGIVNKMLVN
TIGGVIQPGSDLLEIVPLDDTLLVEAKIRPQDIAFLHPGQEATVKFTAYDYTIYGGLKAKLEQIGADTITDEDKKTTYYV
IKLRTERSHLGTDEKPLLIIPGMVASVDIITGKKTVLSYLLKPIIRARAEALHER

Sequences:

>Translated_455_residues
MLLKSGFKDSIRRYFKGSASLQGQPLPEVNKALIEDAPRVVRLTIWAIIGFFVFLMLWANFAVIDEVTKGDGKAIPSSKI
QKIQNLEGGIVSELFVKEGQIVEAGAPLVRLDDTRFASNVGETEADRLSMLLRVERLSAEVDDRPLNFPEDVLKAVPGQA
KSEESLYISRRQQLHDEVGGLQEQLIQRQQELREFTSKQAQYRQQLGLQRQEINMSEPLVAQGAVSPVEVLRLKRAEVET
RGQLDATTLAIPRAESAIKEVQRKIDETRGKFRSEALTQLNEARTDLNKAQATGKALEDRVSRTLVTSPVRGIVNKMLVN
TIGGVIQPGSDLLEIVPLDDTLLVEAKIRPQDIAFLHPGQEATVKFTAYDYTIYGGLKAKLEQIGADTITDEDKKTTYYV
IKLRTERSHLGTDEKPLLIIPGMVASVDIITGKKTVLSYLLKPIIRARAEALHER
>Mature_455_residues
MLLKSGFKDSIRRYFKGSASLQGQPLPEVNKALIEDAPRVVRLTIWAIIGFFVFLMLWANFAVIDEVTKGDGKAIPSSKI
QKIQNLEGGIVSELFVKEGQIVEAGAPLVRLDDTRFASNVGETEADRLSMLLRVERLSAEVDDRPLNFPEDVLKAVPGQA
KSEESLYISRRQQLHDEVGGLQEQLIQRQQELREFTSKQAQYRQQLGLQRQEINMSEPLVAQGAVSPVEVLRLKRAEVET
RGQLDATTLAIPRAESAIKEVQRKIDETRGKFRSEALTQLNEARTDLNKAQATGKALEDRVSRTLVTSPVRGIVNKMLVN
TIGGVIQPGSDLLEIVPLDDTLLVEAKIRPQDIAFLHPGQEATVKFTAYDYTIYGGLKAKLEQIGADTITDEDKKTTYYV
IKLRTERSHLGTDEKPLLIIPGMVASVDIITGKKTVLSYLLKPIIRARAEALHER

Specific function: Involved in the secretion of alkaline protease [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 50715; Mature: 50715

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: PS00543 HLYD_FAMILY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLKSGFKDSIRRYFKGSASLQGQPLPEVNKALIEDAPRVVRLTIWAIIGFFVFLMLWAN
CCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
FAVIDEVTKGDGKAIPSSKIQKIQNLEGGIVSELFVKEGQIVEAGAPLVRLDDTRFASNV
HHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHCCCCEEECCCCEEEECCCHHHHCC
GETEADRLSMLLRVERLSAEVDDRPLNFPEDVLKAVPGQAKSEESLYISRRQQLHDEVGG
CCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCC
LQEQLIQRQQELREFTSKQAQYRQQLGLQRQEINMSEPLVAQGAVSPVEVLRLKRAEVET
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHCCCCCHHHHHHHHHHHHHH
RGQLDATTLAIPRAESAIKEVQRKIDETRGKFRSEALTQLNEARTDLNKAQATGKALEDR
CCCCCHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSRTLVTSPVRGIVNKMLVNTIGGVIQPGSDLLEIVPLDDTLLVEAKIRPQDIAFLHPGQ
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCEEEEEEECCCCCEEEECCCC
EATVKFTAYDYTIYGGLKAKLEQIGADTITDEDKKTTYYVIKLRTERSHLGTDEKPLLII
CCEEEEEEEEEEEECCHHHHHHHHCCCCCCCCCCCEEEEEEEEEECHHHCCCCCCCEEEE
PGMVASVDIITGKKTVLSYLLKPIIRARAEALHER
CCHHHEEEEECCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLLKSGFKDSIRRYFKGSASLQGQPLPEVNKALIEDAPRVVRLTIWAIIGFFVFLMLWAN
CCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
FAVIDEVTKGDGKAIPSSKIQKIQNLEGGIVSELFVKEGQIVEAGAPLVRLDDTRFASNV
HHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHCCCCEEECCCCEEEECCCHHHHCC
GETEADRLSMLLRVERLSAEVDDRPLNFPEDVLKAVPGQAKSEESLYISRRQQLHDEVGG
CCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCC
LQEQLIQRQQELREFTSKQAQYRQQLGLQRQEINMSEPLVAQGAVSPVEVLRLKRAEVET
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHCCCCCHHHHHHHHHHHHHH
RGQLDATTLAIPRAESAIKEVQRKIDETRGKFRSEALTQLNEARTDLNKAQATGKALEDR
CCCCCHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSRTLVTSPVRGIVNKMLVNTIGGVIQPGSDLLEIVPLDDTLLVEAKIRPQDIAFLHPGQ
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCEEEEEEECCCCCEEEECCCC
EATVKFTAYDYTIYGGLKAKLEQIGADTITDEDKKTTYYVIKLRTERSHLGTDEKPLLII
CCEEEEEEEEEEEECCHHHHHHHHCCCCCCCCCCCEEEEEEEEEECHHHCCCCCCCEEEE
PGMVASVDIITGKKTVLSYLLKPIIRARAEALHER
CCHHHEEEEECCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1427098; 10984043 [H]