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The map label for this gene is pntAB [H]

Identifier: 77456341

GI number: 77456341

Start: 115458

End: 115778

Strand: Reverse

Name: pntAB [H]

Synonym: Pfl01_0113

Alternate gene names: 77456341

Gene position: 115778-115458 (Counterclockwise)

Preceding gene: 77456342

Following gene: 77456340

Centisome position: 1.8

GC content: 58.57

Gene sequence:

>321_bases
ATGGAAGAGCTTATCTCCCCCGGTATCTACAACCTGATCATCTTCGTGCTGGCGATTTATGTCGGTTACCACGTGGTCTG
GAACGTTACACCCGCGCTGCACACGCCGCTGATGGCAGTAACCAACGCCATTTCGGCGATCGTGATCGTCGGCGCCATGC
TCGCGGCTGCACTGACCGTCACCCCGCTGGGCAAGACCATGGGCACCCTCGCCGTGGCACTGGCCGCGGTCAATGTGTTC
GGTGGCTTCCTGGTCACCCGCCGCATGCTTGAGATGTTCAAGAAGAAAGCCCCGAAAGCAAAAGAAGAGGCGCCTAAGTA
A

Upstream 100 bases:

>100_bases
CCAGTTCGAAGTAAACCTCGAAGACGATATCGTCGCCGCGTGCCTGATGTGCCGCGACGGCCAAGTCATCCGCAAAAACG
CCTAAGCAGGGATTCAGACG

Downstream 100 bases:

>100_bases
TGAGCATGAACCTCGTCACGACGCTCTACCTGATCGCATCGATCTGCTTCATCCAGGCCCTCAAAGGCCTGTCGCACCCG
ACCACGTCGCGCCGCGGCAA

Product: NAD/NADP transhydrogenase, membrane-spanning dIIa subunit

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit alpha 2; Pyridine nucleotide transhydrogenase subunit alpha 2 [H]

Number of amino acids: Translated: 106; Mature: 106

Protein sequence:

>106_residues
MEELISPGIYNLIIFVLAIYVGYHVVWNVTPALHTPLMAVTNAISAIVIVGAMLAAALTVTPLGKTMGTLAVALAAVNVF
GGFLVTRRMLEMFKKKAPKAKEEAPK

Sequences:

>Translated_106_residues
MEELISPGIYNLIIFVLAIYVGYHVVWNVTPALHTPLMAVTNAISAIVIVGAMLAAALTVTPLGKTMGTLAVALAAVNVF
GGFLVTRRMLEMFKKKAPKAKEEAPK
>Mature_106_residues
MEELISPGIYNLIIFVLAIYVGYHVVWNVTPALHTPLMAVTNAISAIVIVGAMLAAALTVTPLGKTMGTLAVALAAVNVF
GGFLVTRRMLEMFKKKAPKAKEEAPK

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG3288

COG function: function code C; NAD/NADP transhydrogenase alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI122939155, Length=83, Percent_Identity=53.0120481927711, Blast_Score=89, Evalue=7e-19,
Organism=Homo sapiens, GI122939153, Length=83, Percent_Identity=53.0120481927711, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1787887, Length=91, Percent_Identity=50.5494505494505, Blast_Score=92, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17550456, Length=84, Percent_Identity=54.7619047619048, Blast_Score=93, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 11310; Mature: 11310

Theoretical pI: Translated: 10.19; Mature: 10.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEELISPGIYNLIIFVLAIYVGYHVVWNVTPALHTPLMAVTNAISAIVIVGAMLAAALTV
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TPLGKTMGTLAVALAAVNVFGGFLVTRRMLEMFKKKAPKAKEEAPK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MEELISPGIYNLIIFVLAIYVGYHVVWNVTPALHTPLMAVTNAISAIVIVGAMLAAALTV
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TPLGKTMGTLAVALAAVNVFGGFLVTRRMLEMFKKKAPKAKEEAPK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9823893; 8662004 [H]