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The map label for this gene is metI [H]

Identifier: 77456294

GI number: 77456294

Start: 72517

End: 73191

Strand: Direct

Name: metI [H]

Synonym: Pfl01_0066

Alternate gene names: 77456294

Gene position: 72517-73191 (Clockwise)

Preceding gene: 77456293

Following gene: 77456295

Centisome position: 1.13

GC content: 60.44

Gene sequence:

>675_bases
ATGGAAGACCTGATGAGTTTCTTCACCAATATCGACTGGTACGAAATCTGGCTCGCCACTGGCGACACCCTGATGATGCT
CGGCGGTTCGCTGCTGTTCACCGTGCTGCTCGGCCTGCCGCTGGGCGTGCTGCTGTTCCTGTGCAGCCCACGCCAGTTGC
TCGAAGCCAAAGGCGTGTACGCCTTGCTGTCGTTGGTGGTGAACATCCTGCGTTCGCTGCCGTTCATCATTCTGTTGATC
GTGATGATCCCGTTCACCGTGCTGATCACCGGCACCTCGCTCGGCGTGGCCGGTGCGATTCCGCCGCTGGTGGTAGGTGC
AACGCCGTTCTTTGCGCGGCTGGTGGAAACCGCCCTGCGTGAAGTCGATCGCGGCATCATCGAAGCGACCCAGTCGATGG
GTGCGACCACTCGCCAGATCATCATGAACGCCCTGCTGCCGGAGGCCCGTCCGGGCATCTTCGCAGCAATTACGGTGACG
GCGATTACACTGGTTTCCTACACGGCGATGGCCGGTGTGGTCGGTGCCGGTGGCCTGGGTGACTTGGCGATCCGTTTCGG
CTACCAGCGGTTCCAGACTGACGTGATGATCGTGACCGTGGTATTGCTGCTGATTCTGGTGCAAGTGCTGCAAATGGTCG
GCGACCGACTGGTCGTGCACTTCTCGCGCAAATAA

Upstream 100 bases:

>100_bases
TTCCCTACGGGCAATTGACCCTCGCCGTCACCGGTGGCGACATGGACGCAGCTTTCGCCCGCTTCACCGCCGCTGACGTT
CACATGGAGGTGTTGCGCTA

Downstream 100 bases:

>100_bases
CCGGTTTTGTAATGACATGAGCCGGCCATTCGCTGGCAGGCGCCAGACGGGCGCCGTAAAAAGGAGTTAGCTGAATGAAA
AAACTGATTGTTGCCCTGGC

Product: binding-protein dependent transport system inner membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MEDLMSFFTNIDWYEIWLATGDTLMMLGGSLLFTVLLGLPLGVLLFLCSPRQLLEAKGVYALLSLVVNILRSLPFIILLI
VMIPFTVLITGTSLGVAGAIPPLVVGATPFFARLVETALREVDRGIIEATQSMGATTRQIIMNALLPEARPGIFAAITVT
AITLVSYTAMAGVVGAGGLGDLAIRFGYQRFQTDVMIVTVVLLLILVQVLQMVGDRLVVHFSRK

Sequences:

>Translated_224_residues
MEDLMSFFTNIDWYEIWLATGDTLMMLGGSLLFTVLLGLPLGVLLFLCSPRQLLEAKGVYALLSLVVNILRSLPFIILLI
VMIPFTVLITGTSLGVAGAIPPLVVGATPFFARLVETALREVDRGIIEATQSMGATTRQIIMNALLPEARPGIFAAITVT
AITLVSYTAMAGVVGAGGLGDLAIRFGYQRFQTDVMIVTVVLLLILVQVLQMVGDRLVVHFSRK
>Mature_224_residues
MEDLMSFFTNIDWYEIWLATGDTLMMLGGSLLFTVLLGLPLGVLLFLCSPRQLLEAKGVYALLSLVVNILRSLPFIILLI
VMIPFTVLITGTSLGVAGAIPPLVVGATPFFARLVETALREVDRGIIEATQSMGATTRQIIMNALLPEARPGIFAAITVT
AITLVSYTAMAGVVGAGGLGDLAIRFGYQRFQTDVMIVTVVLLLILVQVLQMVGDRLVVHFSRK

Specific function: Part of the ABC transporter complex metNIQ involved in methionine import. Responsible for the translocation of the substrate across the membrane (Probable). It has also been shown to be involved in methionine sulfoxide transport [H]

COG id: COG2011

COG function: function code P; ABC-type metal ion transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786397, Length=203, Percent_Identity=51.7241379310345, Blast_Score=159, Evalue=1e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 24183; Mature: 24183

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDLMSFFTNIDWYEIWLATGDTLMMLGGSLLFTVLLGLPLGVLLFLCSPRQLLEAKGVY
CHHHHHHHHCCCHHEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
ALLSLVVNILRSLPFIILLIVMIPFTVLITGTSLGVAGAIPPLVVGATPFFARLVETALR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHCCCHHHHHHHHHHHH
EVDRGIIEATQSMGATTRQIIMNALLPEARPGIFAAITVTAITLVSYTAMAGVVGAGGLG
HHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHH
DLAIRFGYQRFQTDVMIVTVVLLLILVQVLQMVGDRLVVHFSRK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCC
>Mature Secondary Structure
MEDLMSFFTNIDWYEIWLATGDTLMMLGGSLLFTVLLGLPLGVLLFLCSPRQLLEAKGVY
CHHHHHHHHCCCHHEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
ALLSLVVNILRSLPFIILLIVMIPFTVLITGTSLGVAGAIPPLVVGATPFFARLVETALR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHCCCHHHHHHHHHHHH
EVDRGIIEATQSMGATTRQIIMNALLPEARPGIFAAITVTAITLVSYTAMAGVVGAGGLG
HHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHH
DLAIRFGYQRFQTDVMIVTVVLLLILVQVLQMVGDRLVVHFSRK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]