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The map label for this gene is lpxP [H]

Identifier: 77456240

GI number: 77456240

Start: 14505

End: 15392

Strand: Direct

Name: lpxP [H]

Synonym: Pfl01_0012

Alternate gene names: 77456240

Gene position: 14505-15392 (Clockwise)

Preceding gene: 77456239

Following gene: 77456246

Centisome position: 0.23

GC content: 62.27

Gene sequence:

>888_bases
GTGGAAAAGTTTAAAGGCGCCATGCTGGTTGGCGCTCTGCGGCTGTTTGCCCTGCTTCCGTGGCGGGCCGTGCAGGCCGT
GGGTTCGGCGATCGGCTGGATCATGTGGAAAACCCCCAACCGTTCCCGCGATGTGGTGCGGATCAACCTGGCCAAATGTT
TTCCACAGATGGACCCGGCCGAACGCGAGCGTCTGGTCGGCCAGACCCTGAAAGACATCGGCAAGTCCCTGACCGAAAGC
GCCTGCGCCTGGATCTGGCCCGCTCAGCGTTCCATCGACCTGGTGCGCGAAGTCGAGGGCCTCGAGGTGCTGAAAGACGC
GCTGGCCTCGGGCAAGGGCGTGGTCGGCATCACCAGCCACCTGGGCAACTGGGAAGTGCTCAACCACTTCTATTGCAGTC
AGTGCAAACCGATCATTTTCTACCGGCCGCCGAAGCTCAAGGCTGTGGATGAATTGCTGCGCAAGCAGCGCGTGCAATTG
GGCAACAAAGTCGCCGCATCGACCAAGGAAGGCATCCTCAGTGTCATCAAGGAAGTGCGCAAGGGCGGTCAGGTGGGGAT
TCCTGCGGACCCGGAACCGGCCGAATCCGCCGGGATCTTCGTGCCGTTCTTCGCCACCCAGGCCCTGACCAGCAAGTTCG
TGCCGAACATGCTCGCCGGCGGCAAAGCCGTCGGGGTGTTCCTGCATGCCCTGCGTCTGCCGGACGGTTCCGGCTACAAG
GTGATCCTCGAAGCGGCGCCGGAAGCGATGTACAGCACCGACACCGAAACCTCCTGCGCAGCGATGAGTAAAGTCGTCGA
GCGTTACGTGGCGGCTTATCCGAGCCAGTACATGTGGAGCATGAAGCGCTTCAAGAAGCGTCCGCCGGGTGAGGCGCGCT
GGTACTGA

Upstream 100 bases:

>100_bases
ATGGTCATGGATCACACCCAGGACTGCGACCGCTACGCGCAGCTCGCCAACGGCGGTTAGAATGGCCGCCTCGCGCACAG
CACAAGATCAGGAGTGACCT

Downstream 100 bases:

>100_bases
TCGGCGATGTGCAATTGTGGATAACCCGACGATAAGGGTTATCCACAGCCGTCACGGTTTCTGCCGATCGAGCTTCTTCA
GAAACACCGTCATTTCCTTC

Product: lipid A biosynthesis lauroyl acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MEKFKGAMLVGALRLFALLPWRAVQAVGSAIGWIMWKTPNRSRDVVRINLAKCFPQMDPAERERLVGQTLKDIGKSLTES
ACAWIWPAQRSIDLVREVEGLEVLKDALASGKGVVGITSHLGNWEVLNHFYCSQCKPIIFYRPPKLKAVDELLRKQRVQL
GNKVAASTKEGILSVIKEVRKGGQVGIPADPEPAESAGIFVPFFATQALTSKFVPNMLAGGKAVGVFLHALRLPDGSGYK
VILEAAPEAMYSTDTETSCAAMSKVVERYVAAYPSQYMWSMKRFKKRPPGEARWY

Sequences:

>Translated_295_residues
MEKFKGAMLVGALRLFALLPWRAVQAVGSAIGWIMWKTPNRSRDVVRINLAKCFPQMDPAERERLVGQTLKDIGKSLTES
ACAWIWPAQRSIDLVREVEGLEVLKDALASGKGVVGITSHLGNWEVLNHFYCSQCKPIIFYRPPKLKAVDELLRKQRVQL
GNKVAASTKEGILSVIKEVRKGGQVGIPADPEPAESAGIFVPFFATQALTSKFVPNMLAGGKAVGVFLHALRLPDGSGYK
VILEAAPEAMYSTDTETSCAAMSKVVERYVAAYPSQYMWSMKRFKKRPPGEARWY
>Mature_295_residues
MEKFKGAMLVGALRLFALLPWRAVQAVGSAIGWIMWKTPNRSRDVVRINLAKCFPQMDPAERERLVGQTLKDIGKSLTES
ACAWIWPAQRSIDLVREVEGLEVLKDALASGKGVVGITSHLGNWEVLNHFYCSQCKPIIFYRPPKLKAVDELLRKQRVQL
GNKVAASTKEGILSVIKEVRKGGQVGIPADPEPAESAGIFVPFFATQALTSKFVPNMLAGGKAVGVFLHALRLPDGSGYK
VILEAAPEAMYSTDTETSCAAMSKVVERYVAAYPSQYMWSMKRFKKRPPGEARWY

Specific function: Unknown

COG id: COG1560

COG function: function code M; Lauroyl/myristoyl acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the htrB/msbB family [H]

Homologues:

Organism=Escherichia coli, GI87082094, Length=290, Percent_Identity=29.6551724137931, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1787292, Length=283, Percent_Identity=31.8021201413428, Blast_Score=130, Evalue=7e-32,
Organism=Escherichia coli, GI1788161, Length=297, Percent_Identity=24.5791245791246, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004960
- InterPro:   IPR011920 [H]

Pfam domain/function: PF03279 Lip_A_acyltrans [H]

EC number: 2.3.1.-

Molecular weight: Translated: 32643; Mature: 32643

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKFKGAMLVGALRLFALLPWRAVQAVGSAIGWIMWKTPNRSRDVVRINLAKCFPQMDPA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCEEEEEHHHHCCCCCHH
ERERLVGQTLKDIGKSLTESACAWIWPAQRSIDLVREVEGLEVLKDALASGKGVVGITSH
HHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHC
LGNWEVLNHFYCSQCKPIIFYRPPKLKAVDELLRKQRVQLGNKVAASTKEGILSVIKEVR
CCCHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
KGGQVGIPADPEPAESAGIFVPFFATQALTSKFVPNMLAGGKAVGVFLHALRLPDGSGYK
CCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCE
VILEAAPEAMYSTDTETSCAAMSKVVERYVAAYPSQYMWSMKRFKKRPPGEARWY
EEEECCCHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MEKFKGAMLVGALRLFALLPWRAVQAVGSAIGWIMWKTPNRSRDVVRINLAKCFPQMDPA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCEEEEEHHHHCCCCCHH
ERERLVGQTLKDIGKSLTESACAWIWPAQRSIDLVREVEGLEVLKDALASGKGVVGITSH
HHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHC
LGNWEVLNHFYCSQCKPIIFYRPPKLKAVDELLRKQRVQLGNKVAASTKEGILSVIKEVR
CCCHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
KGGQVGIPADPEPAESAGIFVPFFATQALTSKFVPNMLAGGKAVGVFLHALRLPDGSGYK
CCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCE
VILEAAPEAMYSTDTETSCAAMSKVVERYVAAYPSQYMWSMKRFKKRPPGEARWY
EEEECCCHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]